Clinical Trials at University of Chicago

As of August 2026, 171 paid clinical trials are recruiting at University of Chicago, located at 5841 S MARYLAND AVE # 2115, CHICAGO, IL 60637-1447, phone (773) 702-4601 in Chicago, Illinois. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 27, 2026.

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174 clinical trials at University of Chicago

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MRI Screening in Men at High Risk of Developing Prostate Cancer

for Prostate Cancer Screening

Sites in Chicago & Glenview

Sponsor: University of Chicago

Sex: Male·Age: 18+

Code: NCT05608694·Recruiting·Listed Nov 2022

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Aspirin and Hemocompatibility Events in Chronic Advanced Heart Failure Patients With Assist Device

for Bleeding

Sites in Chicago +2 more locations

Sponsor: Columbia University

Sex: All·Age: 18+

Code: NCT06655376·Phase 4·Recruiting·Listed Oct 2024

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American Lung Association (ALA) Lung Health Cohort

for Lung Diseases

Sites in Chicago +29 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 25 - 35·Accepts healthy volunteers

Code: NCT04543461·Recruiting·Listed Sep 2020

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Hemodynamic ABI Monitor

for Traumatic Brain Injury (TBI)

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 80

Code: NCT06725108·Recruiting·Listed Dec 2024

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Detecting HPV DNA in Anal and Cervical Cancers

for Cervical Cancer

2 locations in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT04857528·Recruiting·Listed Apr 2021

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Left vs Left Randomized Clinical Trial

for Heart Failure

Sites in Chicago, Evanston +55 more locations

Sponsor: Baylor College of Medicine

Sex: All·Age: 18+

Code: NCT05650658·Recruiting·Listed Dec 2022

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Lung Cancer Screening in High-risk Black Individuals

for Lung Cancer

Sites in Chicago +1 more location

Sponsor: Massachusetts General Hospital

Sex: All·Age: 50 - 80·Accepts healthy volunteers

Code: NCT05898594·Recruiting·Listed Jun 2023

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Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future

for LVAD

Sites in Chicago +3 more locations

Sponsor: International Consortium of Circulatory Assist Clinicians

Sex: All·Age: 18 - 100

Code: NCT06039176·Recruiting·Listed Sep 2023

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Women Informed to Screen Depending on Measures of Risk (Wisdom Study)

for Breast Cancer Screening

Sites in Chicago +8 more locations

Sponsor: University of California, San Francisco

Sex: Female·Age: 30 - 74·Accepts healthy volunteers

Code: NCT02620852·Recruiting·Listed Dec 2015

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Percutaneous Nerve Evaluation Trial Time

for Urge Incontinence

1 location in Chicago

Sponsor: University of Chicago

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06226220·Recruiting·Listed Jan 2024

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Genicular Nerve Block After Open Reduction Internal Fixation of Tibial Plateau

for Tibial Plateau Fractures

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT06639503·Phase 1·Recruiting·Listed Oct 2024

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SGLT2i in Kidney Stones

for Kidney Stones

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 70

Code: NCT07055282·EARLY_Phase 1·Recruiting·Listed Jul 2025

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Training for Urinary Leakage Improvement After Pregnancy

for Urinary Incontinence

Sites in Chicago +6 more locations

Sponsor: NICHD Pelvic Floor Disorders Network

Sex: Female·Age: 18+

Code: NCT06411158·Recruiting·Listed May 2024

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Study of Biomarker-Based Treatment of Acute Myeloid Leukemia

for Previously Untreated Relapsed Refractory Acute Myeloid Leukemia

Sites in Chicago +12 more locations

Sponsor: Beat AML, LLC

Sex: All·Age: 18+

Code: NCT03013998·Phase 1, Phase 2·Recruiting·Listed Jan 2017

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PiMZ Longitudinal Cohort (PiMZ Logic)

for Alpha 1-Antitrypsin Deficiency

Sites in Chicago +4 more locations

Sponsor: Columbia University

Sex: All·Age: 18+

Code: NCT06505603·Recruiting·Listed Jul 2024

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Type 1 Diabetes and Obstructive Sleep Apnea

for Sleep Apnea, Obstructive

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 50

Code: NCT06915831·Recruiting·Listed Apr 2025

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Frameless Stereotactic Radiosurgery for Intact Brain Metastases

for Brain Metastases

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT02747303·Phase 2·Recruiting·Listed Apr 2016

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Study of Pelvic Hypofractionated Radiotherapy in Endometrial Cancer

for Endometrial Cancer

Sites in Chicago +3 more locations

Sponsor: University of Chicago

Sex: Female·Age: 18+

Code: NCT04683653·Phase 1, Phase 2·Recruiting·Listed Dec 2020

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Impact of Anti-inflammatory Medications in Patients With Elevated Serum Prostate-specific Antigen

for Elevated Serum PSA

Sites in Chicago +2 more locations

Sponsor: University of Chicago

Sex: Male·Age: 18 - 80

Code: NCT05512754·Phase 4·Recruiting·Listed Aug 2022

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Rare and Atypical Diabetes Network

for Diabetes Mellitus

Sites in Chicago +12 more locations

Sponsor: University of South Florida

Sex: All·Age: All ages

Code: NCT05544266·Recruiting·Listed Sep 2022

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Auricular Acupressure in Prehabilitation

for Frailty

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 50+

Code: NCT06516198·Recruiting·Listed Jul 2024

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Semaglutide for Metabolic Intervention and Adipose Loss to Treat Atrial Fibrillation

for Overweight or Obesity

Drug: Semaglutide

Sites in Chicago +1 more location

Sponsor: University of Chicago

Sex: All·Age: 18 - 75

Code: NCT06499857·Phase 3·Recruiting·Listed Jul 2024

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A Pilot Clinical Evaluation of Astepro® Nasal Spray for Management of Early SARS-CoV-2 Infection

for COVID-19

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06008860·Phase 4·Recruiting·Listed Aug 2023

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Manipulation of the Gut Microbiome by a Standardized Preoperative Diet to Prevent Colorectal Cancer Recurrence and Metastasis Following Surgery

for Colorectal Cancer

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT06349590·Phase 1, Phase 2·Recruiting·Listed Apr 2024

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Improving Mobility After Revascularization in Peripheral Artery Disease

for Peripheral Artery Disease

Sites in Chicago +6 more locations

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT06686121·Phase 3·Recruiting·Listed Nov 2024

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A Trial of Post-Discharge Transitional Care for Patients With Chronic Liver Disease

for Liver Diseases

Sites in Chicago +3 more locations

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT05733832·Recruiting·Listed Feb 2023

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Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

for Huntington's Disease

Sites in Chicago +51 more locations

Sponsor: CHDI Foundation, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT01574053·Recruiting·Listed Apr 2012

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Stereotactic Body Radiotherapy (SBRT) for Early Treatment of Oligometastatic Adenoid Cystic Carcinoma: The SOLAR Trial

for Adenoid Cystic Carcinoma

Sites in Chicago +4 more locations

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT04883671·Recruiting·Listed May 2021

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Genetics of Cardiovascular and Neuromuscular Disease

for Cardiomyopathy

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: All ages

Code: NCT00138931·Recruiting·Listed Aug 2005

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A Novel Intervention for Weight Loss in Young Adults

for Weight Loss

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT06230744·Recruiting·Listed Jan 2024

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myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home

for COPD

Sites in Chicago +24 more locations

Sponsor: Temple University

Sex: All·Age: 30+

Code: NCT05204888·Recruiting·Listed Jan 2022

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New Strategies to Enhance Smoking Cessation

for Smoking Cessation

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT06751927·Recruiting·Listed Dec 2024

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Lynch Syndrome Integrative Epidemiology and Genetics

for Lynch Syndrome

Sites in Chicago +1 more location

Sponsor: University of Colorado, Denver

Sex: All·Age: 18+

Code: NCT06582914·Recruiting·Listed Sep 2024

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Pyrimethamine, Sulfadiazine, and Leucovorin in Treating Patients With Congenital Toxoplasmosis

for Toxoplasmosis

1 location in Chicago

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: All ages

Code: NCT00004317·Phase 4·Recruiting·Listed Oct 1999

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Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial

for Acute Ischemic Stroke

Sites in Chicago, Winfield +49 more locations

Sponsor: Mercy Health Ohio

Sex: All·Age: 18 - 79

Code: NCT05611242·Phase 3·Recruiting·Listed Nov 2022

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Parkinson's Foundation PD GENEration Genetic Registry

for Parkinson's Disease

Sites in Chicago, Evanston +51 more locations

Sponsor: Parkinson's Foundation

Sex: All·Age: 18+

Code: NCT04994015·Recruiting·Listed Aug 2021

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Cardiogenic Shock Working Group Registry

for Cardiogenic Shock

Sites in Chicago +15 more locations

Sponsor: Tufts Medical Center

Sex: All·Age: 18+

Code: NCT04682483·Recruiting·Listed Dec 2020

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Piloting a Culturally Adapted Suicide Prevention for Black Students in Chicago

for Suicide

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 11 - 15·Accepts healthy volunteers

Code: NCT07125144·Recruiting·Listed Aug 2025

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Predict Severe Traumatic Brain Injury

for Traumatic Brain Injury

Sites in Chicago +1 more location

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT06966713·Recruiting·Listed May 2025

Apply to this trial

APPROVE Trial: Evaluating a Prescription Digital Therapeutic for Treatment of OAB in Women

for Overactive Bladder (OAB)

Sites in Chicago +8 more locations

Sponsor: Medstar Health Research Institute

Sex: Female·Age: 22+

Code: NCT06797245·Recruiting·Listed Jan 2025

Apply to this trial