Paid Clinical Trials in Colorado

Colorado has 1,971 paid clinical trials enrolling now across cities including Aurora, Denver and Colorado Springs. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Colorado include University of Colorado Anschutz and National Jewish Health, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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1,971 clinical trials

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An Open-label Extension Safety Study of MELAS Patients Who Completed TIS6463-203 (PRIZM)

for Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome)

9 locations incl. La Jolla

Sponsor: Tisento Therapeutics

Sex: All·Age: All ages

Code: NCT06961344·Phase 2·Enrolling By Invitation

A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etoposide in First-line Extensive Stage Small-Cell Lung Cancer (ES-SCLC)

for Small-cell Lung Cancer

Drug: Durvalumab

44 locations incl. Casa Grande

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07005128·Phase 3·Recruiting

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A Follow-up Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

for Immune Thrombocytopenic Purpura (ITP)

17 locations incl. Los Angeles

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06948318·Phase 3·Recruiting

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Pain Reprocessing Therapy in Post-Operative Knee Pain

for Pain, Chronic

2 locations incl. Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: 18+

Code: NCT06800209·Phase 2·Recruiting

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A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety

for Epileptic Encephalopathy

6 locations incl. San Diego

Sponsor: Praxis Precision Medicines

Sex: All·Age: 1 Day - 18

Code: NCT07019922·Phase 3·Recruiting

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Type 1 Diabetes REst for Metabolic Health

for Type 1 Diabetes (T1D)

1 location in Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: 14 - 19

Code: NCT06627504·Recruiting

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Rademikibart Add-on Treatment of an Acute COPD Exacerbation (Seabreeze STAT COPD)

for COPD Acute Exacerbation

22 locations incl. Birmingham

Sponsor: Connect Biopharm LLC

Sex: All·Age: 40 - 80

Code: NCT06940154·Phase 2·Recruiting

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A Dose Randomization Study of Bulumtatug Fuvedotin in TNBC Patients Previously Treated With ADCs

for Triple Negative Breast Cancer

6 locations incl. Duarte

Sponsor: Mabwell (Shanghai) Bioscience Co., Ltd.

Sex: All·Age: 18+

Code: NCT06908928·Phase 1·Recruiting

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Real-world Experience on Using Nemolizumab in the Treatment of Moderate-to- Severe Prurigo Nodularis in Adults

for Prurigo Nodularis

Drug: Nemolizumab

39 locations incl. Birmingham

Sponsor: Galderma R&D

Sex: All·Age: 18+

Code: NCT06988618·Recruiting

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A Research Study to See How a Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine, Both in Combination With Insulin Aspart, in Adults With Type 1 Diabetes

for Diabetes Mellitus, Type 1

109 locations incl. Cullman

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07076199·Phase 3·Recruiting

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Study of Large Channel Digital Pancreaticobiliary Scope (DPS) With Compatible Accessories

for Bile Duct Adenocarcinoma

1 location in Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: 21+

Code: NCT07120295·Phase 4·Recruiting

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Frontline T-cell Engager vs Autologous Stem Cell Transplant (ASCT) and Measurable Residual Disease (MRD)-Guided Sequential Intensification thERapy in Multiple Myeloma

for Multiple Myeloma, Newly Diagnosed

11 locations incl. Birmingham

Sponsor: SCRI Development Innovations, LLC

Sex: All·Age: 19+

Code: NCT06974786·Phase 2·Recruiting

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Study of Intravenously (IV) Infused Etentamig in Combination With an Oral Cereblon E3 Ligase Modulatory Drug (CELMoD) Agent Assessing Adverse Events and Change in Disease Activity in Adult Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

Drug: Etentamig

7 locations incl. Beverly Hills

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06896916·Phase 1·Recruiting

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A Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory Melanoma

for Melanoma (Skin Cancer)

9 locations incl. Newport Beach

Sponsor: Linnaeus Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06624644·Phase 2, Phase 3·Recruiting

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Pivotal, Prospective, Multi-centre, Single-arm Study to Evaluate the Safety and Effectiveness of Oli for Identification of Patients, During the Intrapartum Period, Who Are at Higher Risk of Developing Abnormal Postpartum Uterine Bleeding, Including Postpartum Haemorrhage

for Post Partum Haemorrhage

5 locations incl. Denver

Sponsor: Baymatob Operations Pty Ltd

Sex: Female·Age: 18+

Code: NCT06655207·Recruiting

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A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

for Prostate Cancer

Drug: Saruparib

42 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: Male·Age: 18+

Code: NCT06952803·Phase 3·Recruiting

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A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes

for Type 1 Diabetes Mellitus

32 locations incl. Scottsdale

Sponsor: Sanofi

Sex: All·Age: 1 - 25

Code: NCT07088068·Phase 3·Recruiting

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A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.

for Breast Cancer

102 locations incl. Chandler

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07062965·Phase 3·Recruiting

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Study to Evaluate the Efficacy and Safety of Deuruxolitinib in Adolescents With Severe Alopecia Areata

for Alopecia Areata

54 locations incl. Birmingham

Sponsor: Sun Pharmaceutical Industries, Inc.

Sex: All·Age: 12 - 17

Code: NCT07133308·Phase 3·Recruiting

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A Study of Dotinurad Versus Allopurinol in Tophaceous Gout

for Tophaceous Gout

Drug: Dotinurad

86 locations incl. Birmingham

Sponsor: Crystalys Therapeutics

Sex: All·Age: 18 - 75

Code: NCT07089888·Phase 3·Recruiting

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Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

for High Grade Glioma

10 locations incl. Aurora

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 1 - 21·Accepts healthy volunteers

Code: NCT06333899·EARLY_Phase 1·Recruiting

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A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

for Non-Squamous Non-Small Cell Lung Cancer

Drug: Osimertinib

14 locations incl. Chandler

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07005102·Phase 2, Phase 3·Recruiting

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Use of an Educational Video to Improve Adherence to Treatment in Voiding Dysfunction

for Dysfunctional Voiding

1 location in Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: 5 - 18

Code: NCT06909552·Not Yet Recruiting

A Phase 1 Study of BMS-986500 as Monotherapy or Combination Therapy in Advanced Solid Tumors

for Advanced Solid Tumor

15 locations incl. Birmingham

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT06997029·Phase 1·Recruiting

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Individualizing Treatment for Asthma in Primary Care (Full Study)

for Asthma

13 locations incl. Aurora

Sponsor: DARTNet Institute

Sex: All·Age: 13 - 75

Code: NCT07052942·Phase 4·Recruiting

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A Study of Dotinurad Versus Allopurinol in Participants With Gout

for Gout

Drug: Dotinurad

80 locations incl. Birmingham

Sponsor: Crystalys Therapeutics

Sex: All·Age: 18 - 75

Code: NCT07089875·Phase 3·Recruiting

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Right Ventricular Response to Exercise Among Patients With Chronic Obstructive Pulmonary Disease

for COPD

1 location in Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: 40+

Code: NCT07576894·Recruiting

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NightWare and Cardiovascular Health in Women With PTSD

for Post Traumatic Stress Disorder

2 locations incl. Aurora

Sponsor: University of Colorado, Denver

Sex: Female·Age: 22 - 40·Accepts healthy volunteers

Code: NCT07021014·Not Yet Recruiting

A Study to Learn About Medicine Called Ritlecitinib in Children Aged Between 6 to 12 Years With Severe Alopecia Areata

for Severe Alopecia Areata

Drug: Ritlecitinib

29 locations incl. Encinitas

Sponsor: Pfizer

Sex: All·Age: 6 - 11

Code: NCT07029711·Phase 3·Recruiting

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A Phase I, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Immunogenicity, Pharmacodynamics, and Preliminary Efficacy of AZD0120 in Participants With Multiple Myeloma (DURGA-2)

for Multiple Myeloma

13 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07073547·Phase 1·Recruiting

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Moderate Aerobic Exercise for Managing Menstrual Cycle Symptoms

for Premenstrual Syndrome

1 location in Colorado Springs

Sponsor: University of Colorado, Colorado Springs

Sex: Female·Age: 18 - 40

Code: NCT07084714·Recruiting

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Inspire UAS High Apnea Hypopnea Index (AHI)/High Body Mass Index (BMI) Post-Approval Study

for Obstructive Sleep Apnea (OSA)

5 locations incl. Colorado Springs

Sponsor: Inspire Medical Systems, Inc.

Sex: All·Age: 18+

Code: NCT07113288·Recruiting

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Endothelial Dysfunction After SCI

for Spinal Cord Injuries

1 location in Englewood

Sponsor: Craig Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07227727·Recruiting

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A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK

for Macular Edema Secondary to Inflammation

55 locations incl. Phoenix

Sponsor: Kodiak Sciences Inc

Sex: All·Age: 18+

Code: NCT06990399·Phase 3·Recruiting

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RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

for Adjustment Disorder

30 locations incl. Birmingham

Sponsor: Reunion Neuroscience Inc

Sex: All·Age: 18 - 80

Code: NCT07002034·Phase 2·Recruiting

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Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of BL-M05D1 in Subjects With Solid Tumors

for Gastric Adenocarcinoma

17 locations incl. Phoenix

Sponsor: SystImmune Inc.

Sex: All·Age: 18+

Code: NCT07021066·Phase 1·Recruiting

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Efficacy and Safety of 186 mcg of OPN-375 Nasal Spray Twice a Day (BID) in Adolescents With Chronic Rhinosinusitis Without Nasal Polyps

for Chronic Rhinosinusitis Without Nasal Polyps

21 locations incl. Gilbert

Sponsor: Optinose US Inc.

Sex: All·Age: 12 - 17

Code: NCT06850805·Phase 3·Recruiting

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Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy.

for Kidney Diseases

7 locations incl. Denver

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT06858319·Phase 3·Recruiting

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Maternal Left Lateral Position in Fetal Growth Restriction

for Fetal Growth Restriction

2 locations incl. Aurora

Sponsor: University of Colorado, Denver

Sex: Female·Age: 18 - 65

Code: NCT06919692·Recruiting

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Neocortical Microarchitecture of Executive Function

for Parkinson Disease

1 location in Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: 45 - 85

Code: NCT06778135·Recruiting

Apply to this trial