Clinical Trials at The Ohio State University

As of September 2026, 138 paid clinical trials are recruiting at The Ohio State University, located at 3600 REED RD UNIT 22, COLUMBUS, OH 43220-4879, phone (614) 293-8000 in Columbus, Ohio. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

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Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 21, 2026.

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139 clinical trials at The Ohio State University

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A Phase 1b/2a Study of Pocenbrodib as Monotherapy and in Combination With Darolutamide in Participants With mCRPC

for mCRPC (Metastatic Castration-resistant Prostate Cancer)

Sites in Columbus, Maumee +17 more locations

Sponsor: Pathos AI, Inc.

Sex: Male·Age: 18+

Code: NCT06785636·Phase 1, Phase 2·Recruiting·Listed Jan 2025

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Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

for Myelofibrosis

Sites in Columbus, Maumee +24 more locations

Sponsor: Disc Medicine, Inc

Sex: All·Age: 18+

Code: NCT05320198·Phase 1, Phase 2·Recruiting·Listed Apr 2022

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A Study to Assess the Efficacy and Safety of Debio 4126 in Participants With Acromegaly Previously Treated With Somatostatin Analogs

for Acromegaly

Sites in Columbus, Cleveland +8 more locations

Sponsor: Debiopharm International SA

Sex: All·Age: 18+

Code: NCT06930625·Phase 3·Recruiting·Listed Apr 2025

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A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease

for Alzheimer's Disease

Sites in Columbus +23 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 50 - 85

Code: NCT07094516·Phase 2·Recruiting·Listed Jul 2025

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Safety and Efficacy of 3 Dose Levels of NMD670 in Adult Patients With Myasthenia Gravis

for Myasthenia Gravis

Sites in Columbus +8 more locations

Sponsor: NMD Pharma A/S

Sex: All·Age: 18+

Code: NCT06414954·Phase 2·Recruiting·Listed May 2024

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Study of BB-031 in Acute Ischemic Stroke Patients (RAISE)

for Acute Ischemic Stroke

Sites in Columbus, Toledo +9 more locations

Sponsor: Basking Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT06226805·Phase 2·Recruiting·Listed Jan 2024

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Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3

for COPD

Sites in Columbus, Cleveland +16 more locations

Sponsor: Apreo Health, Inc.

Sex: All·Age: 40 - 84

Code: NCT06891755·Recruiting·Listed Mar 2025

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Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma

for Peripheral T-Cell Lymphoma, Not Otherwise Specified

Drug: Soquelitinib

Sites in Columbus +20 more locations

Sponsor: Corvus Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06561048·Phase 3·Recruiting·Listed Aug 2024

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Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)

for Chronic Lymphocytic Leukemia (CLL)

Drug: Venetoclax

Sites in Columbus +10 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT04895436·Phase 2·Recruiting·Listed May 2021

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Melodi Matrix™ in Breast Reconstruction

for Breast Reconstruction

Sites in Columbus +9 more locations

Sponsor: Melodi Health, Inc.

Sex: Female·Age: 22+

Code: NCT06027996·Recruiting·Listed Sep 2023

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A Study of STM-416 Administered to Patients Undergoing TURBT for Recurrent Bladder Cancer

for Non-muscle-invasive Bladder Cancer

Sites in Columbus +18 more locations

Sponsor: SURGE Therapeutics

Sex: All·Age: 18+

Code: NCT05710848·Phase 1, Phase 2·Recruiting·Listed Feb 2023

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A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

for Solid Tumor, Adult

Sites in Columbus +9 more locations

Sponsor: A2 Biotherapeutics Inc.

Sex: All·Age: 18+

Code: NCT06682793·Phase 1, Phase 2·Recruiting·Listed Nov 2024

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Cardiac RADIoablation Versus Repeat Catheter Ablation: a Pivotal Randomized Clinical Trial Evaluating Safety and Efficacy for Patients With High-risk Refractory Ventricular Tachycardia (RADIATE-VT)

for Tachycardia, Ventricular

Sites in Columbus +10 more locations

Sponsor: Varian, a Siemens Healthineers Company

Sex: All·Age: 18+

Code: NCT05765175·Recruiting·Listed Mar 2023

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Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated or Spliceosome Mutated Relapsed or Refractory Acute Myeloid Leukemia

for AML With Gene Mutations

Sites in Columbus, Cincinnati +10 more locations

Sponsor: Lomond Therapeutics Holdings, Inc.

Sex: All·Age: 18+

Code: NCT06366789·Phase 1·Recruiting·Listed Apr 2024

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A Study With NVC-001 in Patients With LMNA-related Dilated Cardiomyopathy (SUNBEAM-LMNA)

for LMNA-Related Dilated Cardiomyopathy

Sites in Columbus, Cincinnati +6 more locations

Sponsor: Nuevocor Pte. Ltd.

Sex: All·Age: 18+

Code: NCT07606274·Phase 1, Phase 2·Recruiting·Listed May 2026

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A Study of Amicidin-β Topical Solution for Patients With Surgical or Traumatic Wound Infections

for Surgical Wound Infection

Sites in Columbus +4 more locations

Sponsor: Macro Biologics, Inc.

Sex: All·Age: 18 - 79

Code: NCT07379684·Phase 1·Recruiting·Listed Jan 2026

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A Study of SGT-212 Gene Therapy in Friedreich's Ataxia

for Friedreich's Ataxia (FA)

Sites in Columbus +2 more locations

Sponsor: Solid Biosciences Inc.

Sex: All·Age: 18 - 40

Code: NCT07180355·Phase 1·Recruiting·Listed Sep 2025

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Investigational Trial to Evaluate XC001 Delivered Via an Cardiac Catheter in Subjects With Chronic Angina.

for Refractory Angina

Sites in Columbus, Cincinnati +12 more locations

Sponsor: XyloCor Therapeutics, Inc.

Sex: All·Age: 18 - 85

Code: NCT07048808·Phase 2·Recruiting·Listed Jul 2025

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Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors

for Head and Neck Squamous Cell Carcinoma (HNSCC)

Sites in Columbus +5 more locations

Sponsor: Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT05985655·Phase 1, Phase 2·Recruiting·Listed Aug 2023

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A Study of Lonitoclax (ZE50-0134) in Relapsed or Refractory B-cell Malignancies

for CLL / SLL

Sites in Columbus, Cincinnati +3 more locations

Sponsor: Lomond Therapeutics Holdings, Inc.

Sex: All·Age: 18+

Code: NCT06708897·Phase 1·Recruiting·Listed Nov 2024

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Evaluation of Neoadjuvant Xaluritamig in Localized Prostate Cancer

for Prostate Cancer

Sites in Columbus +6 more locations

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT06613100·Phase 1·Recruiting·Listed Sep 2024

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MagnetOs Flex Matrix Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion

for Degenerative Disc Disease

Sites in Columbus +7 more locations

Sponsor: Kuros Biosurgery AG

Sex: All·Age: 18+

Code: NCT05037968·Recruiting·Listed Sep 2021

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A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving T Cell Engaging Bi/Tri-specific Antibodies Intravenously (IV)/Subcutaneously (SC) Alone or in Combinations

for Multiple Myeloma

Sites in Columbus, Cincinnati +12 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06892522·Phase 1, Phase 2·Recruiting·Listed Mar 2025

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Isatuximab in Combination With Novel Agents in RRMM - Master Protocol

for Plasma Cell Myeloma Refractory

Sites in Columbus +3 more locations

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT04643002·Phase 1, Phase 2·Recruiting·Listed Nov 2020

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Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

for Non Hodgkin Lymphoma

Sites in Columbus, Cincinnati +6 more locations

Sponsor: Newave Pharmaceutical Inc

Sex: All·Age: 13+

Code: NCT04771572·Phase 1·Recruiting·Listed Feb 2021

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Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-Resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass

for Acquired Antithrombin Deficiency

Sites in Columbus, Cleveland +7 more locations

Sponsor: Octapharma

Sex: All·Age: 18 - 85

Code: NCT06096116·Phase 3·Recruiting·Listed Oct 2023

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Trial to Evaluate the Safety & Tolerability of JBZ-001 in Pts With Advanced Solid and Hematological Malignancies

for Solid Tumor

Sites in Columbus +1 more location

Sponsor: Jabez Bioscience, Inc

Sex: All·Age: 18+

Code: NCT06801002·Phase 1·Recruiting·Listed Jan 2025

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Janus II Feasibility

for Sleep Apnea

Sites in Columbus +2 more locations

Sponsor: Zoll Medical Corporation

Sex: All·Age: 22+

Code: NCT06556693·Recruiting·Listed Aug 2024

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Knee Related Subchondral Bone Lesions Treated With IOBP

for Subchondral Cyst

Sites in Columbus +4 more locations

Sponsor: Arthrex, Inc.

Sex: All·Age: 18 - 60

Code: NCT05314608·Recruiting·Listed Apr 2022

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Retrospective Acute Care Appendectomy Study

for Acute Appendicitis

Sites in Columbus +2 more locations

Sponsor: Intuitive Surgical

Sex: All·Age: 22+

Code: NCT06624215·Recruiting·Listed Oct 2024

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Phase 2a Multiple Ascending Dose Study in Hospitalized Patients With Pneumonia.

for Acute Respiratory Distress Syndrome

Sites in Columbus +4 more locations

Sponsor: Vasomune Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05123755·Phase 2·Recruiting·Listed Nov 2021

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Safety and Device Performance of the Uriprene® Degradable Temporary Ureteral Stent Following Uncomplicated Ureteroscopy

for Ureteral Diseases

Sites in Columbus +3 more locations

Sponsor: Adva-Tec

Sex: All·Age: 21 - 80

Code: NCT04565795·Recruiting·Listed Sep 2020

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Determination of Resistance Training Status for Patients on Glucagon-Like Peptide-1 Receptor Agonists

for Obesity & Overweight

1 location in Columbus

Sponsor: Ohio State University

Sex: All·Age: 18+

Code: NCT07702461·Recruiting·Listed Jul 2026

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Upper vs Lower Extremity BP in Spinal Cesarean Using ClearSight

for Anesthesia

1 location in Columbus

Sponsor: Ohio State University

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT07685730·Recruiting·Listed Jul 2026

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A Pilot Study to Evaluate the Effectiveness of Focused Massage on Pain, Mobility, and Quality of Life During Radiation Treatment for Patients With Breast Cancer

for Breast Cancer

1 location in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07447700·Recruiting·Listed Mar 2026

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Reducing Parental Substance Use and Enhancing Family Resilience Among Rural Families Through Ohio START

for Substance Use Disorder (SUD)

1 location in Columbus

Sponsor: Ohio State University

Sex: All·Age: 18+

Code: NCT07278427·Recruiting·Listed Dec 2025

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Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Prospective Outcomes Registry

for Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease

Sites in Columbus, Cleveland +37 more locations

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT01915511·Recruiting·Listed Aug 2013

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Comparison of Intravesical Therapy and Surgery as Treatment Options for Bladder Cancer 2

for Bladder Cancer

Sites in Columbus +5 more locations

Sponsor: University of Washington

Sex: All·Age: 18+

Code: NCT07225127·Recruiting·Listed Nov 2025

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Pancreatic Cancer Early Detection Consortium

for Pancreas Cancer

Sites in Columbus +41 more locations

Sponsor: Arbor Research Collaborative for Health

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT04970056·Recruiting·Listed Jul 2021

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Anti-inflammatory Activities of Vitamin C Supplementation on the Gut Barrier Function in Adults With Obesity

for Adequate Vitamin C Status

1 location in Columbus

Sponsor: Ohio State University

Sex: All·Age: 18 - 50

Code: NCT07151105·Recruiting·Listed Sep 2025

Apply to this trial