Pacritinib Effectiveness in Real-world Settings
for Myelofibrosis (MF)
Drug: Pacritinib
Sites in Columbus +2 more locations
Sponsor: Swedish Orphan Biovitrum
Sex: All·Age: 18+
Code: NCT07774455·Recruiting·Listed Aug 19, 2026
Clinical Trials at The Ohio State University
As of September 2026, 138 paid clinical trials are recruiting at The Ohio State University, located at 3600 REED RD UNIT 22, COLUMBUS, OH 43220-4879, phone (614) 293-8000 in Columbus, Ohio. Active studies at this site cover conditions such as Acute Myeloid Leukemia, Breast Cancer and Chronic Lymphocytic Leukemia. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
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Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Columbus
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
139 clinical trials at The Ohio State University
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A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
for Metastatic Castration-resistant Prostate Cancer
Sites in Columbus, Dayton +43 more locations
Sponsor: Amgen
Sex: Male·Age: 18+
Code: NCT07213674·Phase 3·Recruiting·Listed Oct 2025
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
for Age-related Macular Degeneration (AMD)
Drug: Cemdisiran
Sites in Columbus, Dublin +139 more locations
Sponsor: Regeneron Pharmaceuticals
Sex: All·Age: 50 - 85
Code: NCT06541704·Phase 3·Recruiting·Listed Aug 2024
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial
for Tricuspid Regurgitation
Sites in Columbus, Cincinnati +43 more locations
Sponsor: Edwards Lifesciences
Sex: All·Age: 18+
Code: NCT04097145·Recruiting·Listed Sep 2019
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II
for Refractory Angina
Sites in Columbus, Cincinnati +64 more locations
Sponsor: Shockwave Medical, Inc.
Sex: All·Age: 18+
Code: NCT05102019·Recruiting·Listed Nov 2021
A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease
for Parkinson Disease
Sites in Columbus +44 more locations
Sponsor: Neuron23 Inc.
Sex: All·Age: 40 - 80
Code: NCT06680830·Phase 2·Recruiting·Listed Nov 2024
Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms
for Depressive Disorder, Major
Drug: Seltorexant
Sites in Columbus, Cincinnati +42 more locations
Sponsor: Janssen Research & Development, LLC
Sex: All·Age: 18 - 74
Code: NCT06559306·Phase 3·Recruiting·Listed Aug 2024
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
for Heart Failure
Sites in Columbus +31 more locations
Sponsor: Procyrion
Sex: All·Age: 21+
Code: NCT05677100·Recruiting·Listed Jan 2023
A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy
for Geographic Atrophy
Sites in Columbus, Dayton +53 more locations
Sponsor: Astellas Pharma Global Development, Inc.
Sex: All·Age: All ages
Code: NCT06779773·Recruiting·Listed Jan 2025
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
for Primary Generalized Tonic-Clonic Seizures
Drug: XEN1101
Sites in Columbus, Akron +46 more locations
Sponsor: Xenon Pharmaceuticals Inc.
Sex: All·Age: 12+
Code: NCT05667142·Phase 3·Recruiting·Listed Dec 2022
A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis
for Antineutrophil Cytoplasmic Antibody-associated Vasculitis
Drug: Avacopan
Sites in Columbus, Miamisburg +56 more locations
Sponsor: Amgen
Sex: All·Age: 18 - 100
Code: NCT06072482·Phase 4·Recruiting·Listed Oct 2023
A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder
for Bipolar I Disorder
Drug: Icalcaprant
Sites in Columbus, Cincinnati +31 more locations
Sponsor: AbbVie
Sex: All·Age: 18 - 65
Code: NCT06696755·Phase 2·Recruiting·Listed Nov 2024
Observational Study for Patients at Risk for Chronic Graft-Versus-Host Disease
for cGVHD
Sites in Columbus +30 more locations
Sponsor: Incyte Corporation
Sex: All·Age: 18+
Code: NCT05919511·Recruiting·Listed Jun 2023
Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)
for Liver Neoplasms
Sites in Columbus, Centerville +28 more locations
Sponsor: HistoSonics, Inc.
Sex: All·Age: 22+
Code: NCT06486454·Recruiting·Listed Jul 2024
Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder
for Major Depressive Disorder
Sites in Columbus, Cincinnati +18 more locations
Sponsor: Intra-Cellular Therapies, Inc.
Sex: All·Age: 18 - 65
Code: NCT05850689·Phase 3·Recruiting·Listed May 2023
Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)
for Prostate Cancer
Drug: JANX007
Sites in Columbus, Cincinnati +31 more locations
Sponsor: Janux Therapeutics
Sex: Male·Age: 18 - 100
Code: NCT05519449·Phase 1·Recruiting·Listed Aug 2022
A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes
for Type 1 Diabetes Mellitus
Sites in Columbus, Cincinnati +31 more locations
Sponsor: Sanofi
Sex: All·Age: 1 - 25
Code: NCT07088068·Phase 3·Recruiting·Listed Jul 2025
Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease
for Crohn's Disease
Sites in Columbus, Cincinnati +54 more locations
Sponsor: AbbVie
Sex: All·Age: 18 - 75
Code: NCT06548542·Phase 2·Recruiting·Listed Aug 2024
Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder
for Generalized Anxiety Disorder (GAD)
Sites in Columbus, Cincinnati +45 more locations
Sponsor: AbbVie
Sex: All·Age: 18 - 65
Code: NCT06846320·Phase 2·Recruiting·Listed Feb 2025
Study of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety Disorder
for Generalized Anxiety Disorder
Sites in Columbus +22 more locations
Sponsor: Intra-Cellular Therapies, Inc.
Sex: All·Age: 18+
Code: NCT06701903·Phase 2·Recruiting·Listed Nov 2024
A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
for Treatment Resistant Depression
Sites in Columbus, Garfield Heights +51 more locations
Sponsor: LivaNova
Sex: All·Age: 18+
Code: NCT03887715·Recruiting·Listed Mar 2019
A Study to Test How Effective Belumosudil Tablets Are for Treating Adult Participants With Chronic Lung Allograft Dysfunction
for Lung Transplant Rejection
Sites in Columbus, Cleveland +30 more locations
Sponsor: Sanofi
Sex: All·Age: 18+
Code: NCT06082037·Phase 3·Recruiting·Listed Oct 2023
The PREDICT Registry:
for DCIS
Sites in Columbus, Akron +28 more locations
Sponsor: PreludeDx
Sex: Female·Age: 30 - 85
Code: NCT03448926·Recruiting·Listed Feb 2018
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
for Functional Mitral Regurgitation
Sites in Columbus, Dayton +49 more locations
Sponsor: Cardiac Dimensions, Inc.
Sex: All·Age: 18+
Code: NCT03142152·Recruiting·Listed May 2017
IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)
for Advanced Melanoma
Drug: Nivolumab
Sites in Columbus +32 more locations
Sponsor: Immunocore Ltd
Sex: All·Age: 18+
Code: NCT06112314·Phase 3·Recruiting·Listed Nov 2023
A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma
for Metastatic Uveal Melanoma
Drug: Nivolumab
Sites in Columbus +28 more locations
Sponsor: Replimune, Inc.
Sex: All·Age: All ages
Code: NCT06581406·Phase 2, Phase 3·Recruiting·Listed Sep 2024
Registry for Stage 2 Type 1 Diabetes
for Type 1 Diabetes
Sites in Columbus, Cincinnati +35 more locations
Sponsor: Sanofi
Sex: All·Age: All ages
Code: NCT06481904·Recruiting·Listed Jul 2024
Trial to Evaluate the Safety and Effectiveness of Treatment With COMS One Device in Subjects With Diabetic Foot Ulcers
for Diabetic Foot Ulcer
Sites in Columbus +25 more locations
Sponsor: Piomic Medical
Sex: All·Age: 22 - 90
Code: NCT05758545·Recruiting·Listed Mar 2023
A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
for Treatment Resistant Depression
Sites in Columbus, North Canton +32 more locations
Sponsor: atai Therapeutics, Inc.
Sex: All·Age: 18 - 65
Code: NCT06524830·Phase 2·Recruiting·Listed Jul 2024
AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM
for Heart Failure
Sites in Columbus, Cincinnati +35 more locations
Sponsor: Cordio Medical
Sex: All·Age: 22+
Code: NCT06378632·Recruiting·Listed Apr 2024
Non-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous Administration in Adult Participants With Multiple Sclerosis
for Multiple Sclerosis
Drug: Frexalimab
Sites in Columbus +22 more locations
Sponsor: Sanofi
Sex: All·Age: 18 - 60
Code: NCT07325292·Phase 3·Recruiting·Listed Jan 2026
A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton's Tyrosine Kinase Inhibitor and a B-cell Lymphoma-2 Inhibitor (DAYBreak CLL-201)
for Chronic Lymphocytic Leukemia (CLL)
Sites in Columbus, Fairfield +25 more locations
Sponsor: Nurix Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT07221500·Phase 2·Recruiting·Listed Oct 2025
A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062)
for Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Sites in Columbus +22 more locations
Sponsor: Merck Sharp & Dohme LLC
Sex: All·Age: 18+
Code: NCT07266831·Phase 2, Phase 3·Recruiting·Listed Dec 2025
A Study to Learn About the Effects of Felzartamab Infusions in Adults With Kidney Transplants Who Have Late Isolated Microvascular Inflammation
for Microvascular Inflammation
Sites in Columbus, Cleveland +21 more locations
Sponsor: Biogen
Sex: All·Age: 18 - 74
Code: NCT07219043·Phase 2·Recruiting·Listed Oct 2025
Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC
for Non-small Cell Lung Cancer
Sites in Columbus, Cincinnati +20 more locations
Sponsor: Nuvalent Inc.
Sex: All·Age: 18+
Code: NCT06765109·Phase 3·Recruiting·Listed Jan 2025
Onyx™ Liquid Embolic IDE Clinical Study
for Peripheral Arterial Hemorrhage
Sites in Columbus, Cleveland +16 more locations
Sponsor: Medtronic Endovascular
Sex: All·Age: 22+
Code: NCT06742801·Recruiting·Listed Dec 2024
Post-market Safety and Effectiveness of the CORUS-LX System in Improving Lumbar Interbody Fusion Outcomes
for Radiculopathy Lumbar
Sites in Columbus +10 more locations
Sponsor: Providence Medical Technology, Inc.
Sex: All·Age: 18 - 80
Code: NCT07222787·Recruiting·Listed Oct 2025
Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors
for Ovarian Cancer
Sites in Columbus +16 more locations
Sponsor: Xencor, Inc.
Sex: All·Age: 15+
Code: NCT06276491·Phase 1·Recruiting·Listed Feb 2024
Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
for Treatment Resistant Depression
Sites in Columbus, Cleveland +23 more locations
Sponsor: Abbott Medical Devices
Sex: All·Age: 22 - 70
Code: NCT06423430·Recruiting·Listed May 2024
Investigations of Reproductive Cancers in Women
for Uterine Cancer
Sites in Columbus, Akron +11 more locations
Sponsor: PinkDx, Inc.
Sex: Female·Age: 45 - 100
Code: NCT06527157·Recruiting·Listed Jul 2024
Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis
for Sickle Cell Disease Vaso-occlusive Crisis
Sites in Columbus, Cincinnati +17 more locations
Sponsor: CSL Behring
Sex: All·Age: 12+
Code: NCT06699849·Phase 2·Recruiting·Listed Nov 2024
Common conditions studied in Columbus
- Acute Myeloid Leukemia (20 active studies)
- Breast Cancer (19 active studies)
- Chronic Lymphocytic Leukemia (18 active studies)
- Ovarian Cancer (17 active studies)
- Endometrial Cancer (16 active studies)
- Malignant Solid Neoplasm (14 active studies)
Leading research sponsors in Columbus
- Ohio State University
- Ohio State University Comprehensive Cancer Center
- National Cancer Institute (NCI)
- Nationwide Children's Hospital
- AstraZeneca
Frequently asked questions
How many paid clinical trials are currently recruiting in Columbus?
There are approximately 1,375 recruiting clinical trials in Columbus, Ohio listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Columbus pay participants?
Most recruiting trials in Columbus compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Columbus?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Columbus?
The most common conditions under active study in Columbus include Acute Myeloid Leukemia (20), Breast Cancer (19), Chronic Lymphocytic Leukemia (18), Ovarian Cancer (17), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Columbus?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Columbus on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Columbus?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Columbus?
Recruiting research sites in Columbus include Ohio State University Comprehensive Cancer Center, Nationwide Children's Hospital, The Ohio State University, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Columbus right now?
The largest active categories in Columbus are Cancer & tumors (492), Cardiovascular (81), Neurology & pain (70). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of The Ohio State University?
The Ohio State University is located at 3600 REED RD UNIT 22, COLUMBUS, OH 43220-4879. Use the Google Maps link in the intro above to get directions.
How do I contact The Ohio State University?
You can reach The Ohio State University by phone at (614) 293-8000. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.
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