Paid Clinical Trials in Daphne, AL
As of July 2026, 24 paid clinical trials are recruiting in Daphne, Alabama. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Daphne offers studies at sites including Gulf Health Hospitals Inc/Infirmary Cancer Care - Malbis for conditions such as Breast Cancer, Recurrent Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8, Breast Neoplasms. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Daphne
Trials by drug in Daphne
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Newly added in Daphne
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
24 clinical trials
A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)
A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer
A Study of Alisertib in Patients With Extensive Stage Small Cell Lung Cancer
A Study to Compare the Efficacy and Safety of BMS-986489 (BMS-986012+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).
MYLUNG Consortium Part 3: Observational Study
A Safety and Efficacy Study of EIK1001 in Combination With Pembrolizumab and Chemotherapy in Participants With Stage 4 Non-Small Cell Lung Cancer.
Pembrolizumab (MK-3475) Plus Investigational Agents in Resectable Non-small Cell Lung Cancer (NSCLC) (MK-3475-01E/KEYMAKER-U01)
Pivotal Study on the NOVABLOC System for Patients Undergoing Primary Total Knee Arthroplasty
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)
Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)
Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)
BMS-986489 (Atigotatug + Nivolumab) vs Durvalumab in Limited-stage Small-cell Lung Cancer (TIGOS-LS)
A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)
Top Research Study Locations in Daphne
Researchers run research studies in Daphne, AL at 8 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Gulf Health Hospitals Inc/Infirmary Cancer Care - Malbis | Recurrent Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8, Locally Advanced Lung Non-Small Cell Carcinoma | 5 |
| Southern Cancer Center, PC | Breast Cancer, Carcinoma, Non-Small-Cell Lung, Breast Neoplasms | 5 |
| Southern Cancer Center | Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer, Limited Stage Small Cell Lung Cancer, Non-Small Cell Lung Cancer Metastatic | 4 |
| Alliance For Multispecialty Research - Daphne | Atherosclerotic Cardiovascular Disease, Cardiovascular Disease, Obesity | 2 |
| Southern Cancer Center Pc | Non-Small Cell Lung Cancer (NSCLC), Non-small Cell Lung Cancer (NSCLC) | 2 |
| Southern Cancer Center (SCC) | Breast Neoplasms, Lung Neoplasm Malignant | 2 |
| Alabama Orthopedic Sports Medicine & Baldwin County Surgery Center | Pain | 1 |
| Southern Cancer Center, P.C. | Non Small Cell Lung Cancer (Squamous or Non Squamous), Stage 4 NSCLC | 1 |
Active & Upcoming Studies in Daphne (2026)
Recruiting trials in Daphne grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (18 active studies)
- A Safety and Efficacy Study of EIK1001 in Combination With Pembrolizumab and Chemotherapy in Participants With Stage 4 Non-Small Cell Lung Cancer. · Phase 2, Phase 3 · Eikon Therapeutics
- A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201) · Phase 3 · Bristol-Myers Squibb
Diabetes & metabolic (2 active studies)
- A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Alone or in Combination With Dapagliflozin Compared With Placebo in Adults With Type 2 Diabetes Mellitus · Phase 3 · AstraZeneca
- Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity · Phase 3 · Amgen
Neurology & pain (1 active study)
Common conditions studied in Daphne
- Breast Cancer (3 active studies)
- Recurrent Lung Non-Small Cell Carcinoma (3 active studies)
- Stage IV Lung Cancer AJCC v8 (3 active studies)
- Breast Neoplasms (2 active studies)
- Carcinoma, Non-Small-Cell Lung (2 active studies)
- Atherosclerotic Cardiovascular Disease (1 active study)
Leading research sponsors in Daphne
- SWOG Cancer Research Network
- Bristol-Myers Squibb
- Amgen
- AstraZeneca
- Merck Sharp & Dohme LLC
Frequently asked questions
How many paid clinical trials are currently recruiting in Daphne?
There are approximately 24 recruiting clinical trials in Daphne, Alabama listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Daphne pay participants?
Most recruiting trials in Daphne compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Daphne?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Daphne?
The most common conditions under active study in Daphne include Breast Cancer (3), Recurrent Lung Non-Small Cell Carcinoma (3), Stage IV Lung Cancer AJCC v8 (3), Breast Neoplasms (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Daphne?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Daphne on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Daphne?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Daphne?
Recruiting research sites in Daphne include Gulf Health Hospitals Inc/Infirmary Cancer Care - Malbis, Southern Cancer Center, PC, Southern Cancer Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Daphne right now?
The largest active categories in Daphne are Cancer & tumors (18), Diabetes & metabolic (2), Neurology & pain (1). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.