Paid Clinical Trials in Des Moines, IA
As of August 2026, 139 paid clinical trials are recruiting in Des Moines, Iowa. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Des Moines offers studies at sites including Iowa Methodist Medical Center for conditions such as Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8, Acute Myeloid Leukemia, Breast Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Des Moines
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Researchers run research studies in Des Moines, IA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Iowa Methodist Medical Center | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Chronic Lymphocytic Leukemia | 77 |
| UI Health Care Mission Cancer and Blood - Laurel Clinic | Anatomic Stage II Breast Cancer AJCC v8, Malignant Solid Neoplasm, Stage III Laryngeal Cancer AJCC v8 | 75 |
| UI Health Care Mission Cancer and Blood - Des Moines Clinic | Anatomic Stage II Breast Cancer AJCC v8, Malignant Solid Neoplasm, Stage III Laryngeal Cancer AJCC v8 | 74 |
| Mercy Medical Center - Des Moines | Anatomic Stage II Breast Cancer AJCC v8, Stage III Laryngeal Cancer AJCC v8, Stage III Lip and Oral Cavity Cancer AJCC v8 | 68 |
| Broadlawns Medical Center | Anatomic Stage II Breast Cancer AJCC v8, Lung Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8 | 40 |
| Blank Children's Hospital | B Acute Lymphoblastic Leukemia, Malignant Solid Neoplasm, Acute Myeloid Leukemia | 24 |
| Iowa Lutheran Hospital | Acral Lentiginous Melanoma, Clinical Stage IV Cutaneous Melanoma AJCC v8, Malignant Digestive System Neoplasm | 7 |
| Mission Cancer and Blood - Laurel | Anatomic Stage IV Breast Cancer AJCC v8, Cardiotoxicity, Elevated CA15-3 or CEA or CA27-29 | 4 |
| Medical Oncology and Hematology Associates-Des Moines | Acral Lentiginous Melanoma, Cancer, Clinical Stage IV Cutaneous Melanoma AJCC v8 | 3 |
| MercyOne Des Moines Medical Center | Lumbar Spinal Stenosis, Mitral Valve Regurgitation | 2 |
| Mission Cancer + Blood - IMMC | Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer, KRAS G12C Lung Cancer, Non-Small Cell Lung Cancer | 2 |
| Mission Cancer and Blood - Des Moines | Cancer, Hodgkin Lymphoma, Non-Hodgkin Lymphoma | 2 |
| University of Iowa Health Care | Follicular Lymphoma (FL), Chronic Lymphocytic Leukemia | 2 |
| ACCOMPLISH-2 Research Site | Chronic Weight Management, Obesity, Overweight | 1 |
| Central Iowa Hospital Corp - UnityPoint Health | COPD | 1 |
| Department of Health and Human Services | Mental Health Disorder | 1 |
| Exinia Research | Acute Gout Flare, Acute Gouty Arthritis, Gout Flare | 1 |
| Harbor View Medical | Orthopedic Disorder | 1 |
| Home-based telemedicine | Chronic Granulomatous Disease (CGD) | 1 |
| John Stoddard Cancer Center | Ovarian Cancer | 1 |
| MercyOne Iowa Heart Center | Aortic Stenosis | 1 |
| Mission Cancer & Blood - John Stoddard Cancer Center | Triple Negative Breast Cancer | 1 |
| Mission Cancer + Blood | MF, Myelofibrosis, Post-ET Myelofibrosis | 1 |
| Mission Cancer + Blood (Exigent Network) | Gastric Cancer, Gastroesophageal-junction Cancer, HER2-positive Gastric Cancer | 1 |
| Mission Cancer + Blood - Mission Cancer Foundation | Non-small Cell Lung Cancer | 1 |
Active & Upcoming Studies in Des Moines (2026)
Recruiting trials in Des Moines grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (104 active studies)
- Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial · Phase 3 · National Cancer Institute (NCI)
- Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations · Phase 3 · SWOG Cancer Research Network
Mental health & behavior (2 active studies)
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
- Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program · Phase 3 · Alliance for Clinical Trials in Oncology
Diabetes & metabolic (1 active study)
- A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2) · Phase 3 · Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Common conditions studied in Des Moines
- Malignant Solid Neoplasm (6 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (5 active studies)
- Acute Myeloid Leukemia (4 active studies)
- Breast Cancer (4 active studies)
- Chronic Lymphocytic Leukemia (4 active studies)
- Stage III Laryngeal Cancer AJCC v8 (4 active studies)
Leading research sponsors in Des Moines
- National Cancer Institute (NCI)
- SWOG Cancer Research Network
- Alliance for Clinical Trials in Oncology
- Children's Oncology Group
- NRG Oncology
Frequently asked questions
How many paid clinical trials are currently recruiting in Des Moines?
There are approximately 139 recruiting clinical trials in Des Moines, Iowa listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Des Moines pay participants?
Most recruiting trials in Des Moines compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Des Moines?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Des Moines?
The most common conditions under active study in Des Moines include Malignant Solid Neoplasm (6), Anatomic Stage II Breast Cancer AJCC v8 (5), Acute Myeloid Leukemia (4), Breast Cancer (4), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Des Moines?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Des Moines on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Des Moines?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Des Moines?
Recruiting research sites in Des Moines include Iowa Methodist Medical Center, UI Health Care Mission Cancer and Blood - Laurel Clinic, UI Health Care Mission Cancer and Blood - Des Moines Clinic, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Des Moines right now?
The largest active categories in Des Moines are Cancer & tumors (104), Mental health & behavior (2), Diabetes & metabolic (1). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.