Oncology Clinical Trials in Gainesville, FL

As of August 2026, 81 paid clinical trials are recruiting for Oncology in Gainesville, Florida. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 31, 2026.

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81 clinical trials for Oncology

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Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity

for Gastric Adenocarcinoma

Sites in Gainesville +77 more locations

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT07001748·Phase 2, Phase 3·Recruiting·Listed Jun 2025

Apply to this trial

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for Hematologic Malignancies

Sites in Gainesville, Jacksonville +111 more locations

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01351545·Recruiting·Listed May 2011

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Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma

for Neuroblastoma

Sites in Gainesville, Orlando +18 more locations

Sponsor: Giselle Sholler

Sex: All·Age: 12 Months - 21

Code: NCT05489887·Phase 2·Recruiting·Listed Aug 2022

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Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

for Atypical Teratoid/Rhabdoid Tumor

Sites in Gainesville, Orlando +12 more locations

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: Up to 26

Code: NCT06465199·Phase 1, Phase 2·Recruiting·Listed Jun 2024

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Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

for Neuroblastoma

Drug: CX-4945

Sites in Gainesville, Orlando +19 more locations

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: Up to 30

Code: NCT06541262·Phase 1, Phase 2·Recruiting·Listed Aug 2024

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Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

for Metastatic Colorectal Carcinoma

Sites in Gainesville +12 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05803382·Phase 1·Recruiting·Listed Apr 2023

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Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)

for Advanced Malignant Solid Neoplasm

Sites in Gainesville +26 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06311214·Phase 2·Recruiting·Listed Mar 2024

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The Florida ASCENT Study

for Cancer

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 100

Code: NCT07042243·Recruiting·Listed Jun 2025

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Novel RNA-lipid Particle (RNA-LP) Vaccine for Anti-PD-1 Antibody Therapy Sensitization

for Melanoma

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 99

Code: NCT05264974·Phase 1·Recruiting·Listed Mar 2022

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TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer

for Breast Carcinoma

Sites in Gainesville & Jacksonville

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT05507879·Recruiting·Listed Aug 2022

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AD HOC Trial: Artificial Intelligence-Based Drug Dosing In Hepatocellular Carcinoma

for Hepatocellular Carcinoma

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 99

Code: NCT05669339·Phase 2·Recruiting·Listed Dec 2022

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Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types

for Bile Duct Cancer

Drug: Atezolizumab

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 99

Code: NCT05000294·Phase 1, Phase 2·Recruiting·Listed Aug 2021

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Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

for Lung Non-Small Cell Carcinoma

Sites in Gainesville +242 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06116682·Phase 2·Recruiting·Listed Nov 2023

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Transdiagnostic Intervention to Reduce Internalized Health-Related Stigma

for Obesity

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18+

Code: NCT05561595·Recruiting·Listed Sep 2022

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PEACH TRIAL- Precision Medicine and Adoptive Cellular Therapy

for Neuroblastoma

Sites in Gainesville +1 more location

Sponsor: University of Florida

Sex: All·Age: 1 - 30

Code: NCT04837547·Phase 1·Recruiting·Listed Apr 2021

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Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

for Neuroblastoma

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 6 Months - 25

Code: NCT06625190·Phase 1, Phase 2·Recruiting·Listed Oct 2024

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Preoperative Nicotine Cessation for Women With Breast Cancer Recommended for Reconstruction

for Breast Cancer

1 location in Gainesville

Sponsor: University of Florida

Sex: Female·Age: 18 - 80

Code: NCT06461650·Recruiting·Listed Jun 2024

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Testing A New Anti-cancer Drug Combination, Entinostat and ZEN003694, for Advanced and Refractory Solid Tumors

for Advanced Malignant Solid Neoplasm

Sites in Gainesville +2 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05053971·Phase 1, Phase 2·Recruiting·Listed Sep 2021

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High Intensity Focused Ultrasound in Prostate Cancer

for Prostate Cancer

1 location in Gainesville

Sponsor: University of Florida

Sex: Male·Age: 18+

Code: NCT06402357·Phase 2·Recruiting·Listed May 2024

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Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases

for Acute Lymphoblastic Leukemia

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 6 Months - 39

Code: NCT05800210·Phase 2·Recruiting·Listed Apr 2023

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A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)

for Adult Glioblastoma

Sites in Gainesville +1 more location

Sponsor: University of Florida

Sex: All·Age: 4+

Code: NCT04573140·Phase 1·Recruiting·Listed Oct 2020

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RNA-Lipid Particle (RNA-LP) Vaccines for Recurrent Adult Glioblastoma (GBM)

for Recurrent Glioblastoma

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 80

Code: NCT06389591·Phase 1·Recruiting·Listed Apr 2024

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IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Adult Glioblastoma

for Glioblastoma Multiforme

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 80

Code: NCT05353530·Phase 1·Recruiting·Listed Apr 2022

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Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

for Diffuse Large B-Cell Lymphoma

Sites in Gainesville +82 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05633615·Phase 2·Recruiting·Listed Dec 2022

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Using Plasma Human Papillomavirus (HPV)-Related Deoxyribonucleic Acid (DNA) and Ribonucleic Acid (RNA) to Follow Response of Cervical Cancer to Surgery, Radiation, and Chemotherapy

for Cervical Cancer

1 location in Gainesville

Sponsor: University of Florida

Sex: Female·Age: 18 - 89

Code: NCT07214584·Recruiting·Listed Oct 2025

Apply to this trial

A Multilevel Approach to Connecting Underrepresented Populations to Clinical Trials

for Cancer

Sites in Gainesville, Jacksonville & Miami

Sponsor: University of Florida

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT05655494·Recruiting·Listed Dec 2022

Apply to this trial

Intravesical Gemcitabine and Docetaxel for Low Grade Intermediate Risk Bladder Cancer

for Bladder Cancer

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18+

Code: NCT06488222·Phase 2·Recruiting·Listed Jul 2024

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Modernizing Instructions to Improve Treatment Participation of Subjects During Their First Radiotherapy

for Cancer

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 99

Code: NCT06246409·Recruiting·Listed Feb 2024

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A Study Evaluating the Feasibility and Compliance of Manual Lymphatic Drainage Comparing Indocyanine-Green (ICG) Guided vs. Traditional Guided in Patients Undergoing Axillary Node Dissection for the Treatment of Breast Cancer

for Breast Cancer

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 99

Code: NCT06327490·Phase 2·Recruiting·Listed Mar 2024

Apply to this trial

Pharmacokinetics and Safety of Epidiferphane and Taxanes in Breast Cancer Patients

for Breast Cancer

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 99

Code: NCT05074290·Phase 1, Phase 2·Recruiting·Listed Oct 2021

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Novel Cavity Marking Technique in Breast Cancer Patients Undergoing Breast Conservation Surgery With Oncoplastic Reconstruction for the Delivery of Adjuvant Radiotherapy and Accuracy of Recommended Re-excisions

for Ductal Carcinoma in Situ

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18+

Code: NCT06903468·Recruiting·Listed Mar 2025

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OPTIMUS PRIME: Safety and Feasibility of OPTune GIO® Integrated With MRI-gUided Laser Ablation Surgery and Pembrolizumab for Recurrent GlIoblastoMa, A randomizEd Trial

for Recurrent Glioblastoma

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 90

Code: NCT06558214·Phase 2·Recruiting·Listed Aug 2024

Apply to this trial

High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers

for Metastatic Prostate Cancer

Sites in Gainesville, Orlando +15 more locations

Sponsor: VA Office of Research and Development

Sex: Male·Age: 18+

Code: NCT05011383·Phase 2·Recruiting·Listed Aug 2021

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Nephroureterectomy With and Without Lymph Node Dissection for Upper Tract Urothelial Cell Carcinoma

for Urothelial Carcinoma

Sites in Gainesville +3 more locations

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 19+

Code: NCT06262516·Recruiting·Listed Feb 2024

Apply to this trial

All-extremity Exercise During Breast Cancer Chemotherapy

for Breast Cancer

1 location in Gainesville

Sponsor: University of Florida

Sex: Female·Age: 18 - 85

Code: NCT04914663·Recruiting·Listed Jun 2021

Apply to this trial

Exercise to ReGain Stamina and Energy (The EXERGISE Study)

for Fatigue

1 location in Gainesville

Sponsor: University of Florida

Sex: Female·Age: 60 - 105

Code: NCT05684367·Recruiting·Listed Jan 2023

Apply to this trial

Clinical Orthopaedic Data Bank (Acute and Chronic)

for Osteoarthritis

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: All ages

Code: NCT00411060·Recruiting·Listed Dec 2006

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A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02)

for Biliary Tract Cancer

Drug: Rilvegostomig

Sites in Gainesville, Jacksonville +34 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07221253·Phase 3·Recruiting·Listed Oct 2025

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Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

for Metastatic Malignant Solid Neoplasm

Sites in Gainesville +17 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05372614·Phase 1·Recruiting·Listed May 2022

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A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

for Non-small Cell Lung Cancer

Drug: Rilvegostomig

Sites in Gainesville, Jacksonville +63 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06692738·Phase 3·Recruiting·Listed Nov 2024

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Conditions in Oncology (Gainesville, FL)

Solid tumor· 14 Breast cancer· 12 Non-small cell lung cancer (NSCLC)· 8 Neuroblastoma· 7 Acute myeloid leukemia (AML)· 6 Cancer (any)· 5 Prostate cancer· 4 Bladder cancer· 4 Ovarian cancer· 4 Myelodysplastic syndromes (MDS)· 4 Osteosarcoma· 4 Lung cancer· 3 Colorectal cancer· 3 Glioblastoma· 3 Non-Hodgkin lymphoma· 3 Ewing sarcoma· 3 Pancreatic cancer· 2 Gastric cancer· 2 Liver cancer· 2 Biliary tract cancer· 2 Endometrial cancer· 2 Glioma· 2 Acute lymphoblastic leukemia· 2 Leukemia (other)· 2 Hematologic malignancy· 2 Melanoma· 2 Soft tissue sarcoma· 2 Rhabdomyosarcoma· 2 Small cell lung cancer· 1 Esophageal cancer· 1 Gastroesophageal junction cancer· 1 Gastrointestinal cancer· 1 Metastatic prostate cancer· 1 Cervical cancer· 1 Gynecologic cancer· 1 Brain metastases· 1 Multiple myeloma· 1 Chronic lymphocytic leukemia (CLL)· 1 Myeloproliferative neoplasm· 1 Hodgkin lymphoma· 1 Diffuse large B-cell lymphoma (DLBCL)· 1 Skin cancer· 1 Head and neck cancer· 1 Neuroendocrine tumors· 1