SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
for Glioma
Sites in Gainesville, Jacksonville +40 more locations
Sponsor: Nuvation Bio Inc.
Sex: All·Age: 18+
Code: NCT05303519·Phase 3·Recruiting·Listed Mar 2022
Glioma Clinical Trials in Gainesville, FL
As of July 2026, 3 paid clinical trials are recruiting for Glioma in Gainesville, Florida. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Related specialties in Gainesville
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3 clinical trials for Glioma
·Clear filters·↓ Download CSVTrametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)
for Recurrent World Health Organization (WHO) Grade II Glioma
Drug: Trametinib
Sites in Gainesville +14 more locations
Sponsor: University of California, San Francisco
Sex: All·Age: 1 - 25
Code: NCT04485559·Phase 1·Recruiting·Listed Jul 2020
A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)
for Adult Glioblastoma
Sites in Gainesville +1 more location
Sponsor: University of Florida
Sex: All·Age: 4+
Code: NCT04573140·Phase 1·Recruiting·Listed Oct 2020
Top Research Study Locations in Gainesville
Researchers run research studies in Gainesville, FL at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Florida | Parkinson Disease, Breast Cancer, Cancer | 210 |
| UF Health Cancer Institute - Gainesville | Acute Myeloid Leukemia, Metastatic Malignant Solid Neoplasm, Advanced Malignant Solid Neoplasm | 45 |
| University of Florida Health | Acute Pancreatitis, Advanced Solid Tumors, Astrocytoma, Grade IV | 12 |
| North Florida/South Georgia Veterans Health System, Gainesville, FL | Alcohol Use Disorder (AUD), Atherosclerosis, Brain Injury | 9 |
| University of Florida College of Medicine | Sepsis, Septic Shock, COVID-19, Coronavirus Infections | 9 |
| Malcom Randall Veterans Administration Medical Center | Stage IV Lung Cancer AJCC v8, Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum | 8 |
| Vitreo Retinal Associates | Stargardt Disease, Cone Rod Dystrophy, Juvenile Macular Degeneration | 8 |
| The Cardiac and Vascular Institute | Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia, Coronary Arterial Disease (CAD) | 7 |
| UF Health | Adult Glioblastoma, Brain Metastases, Cognitive Dysfunction | 7 |
| UF Health Shands Hospital | Aneurysm of Aorta, Thoracic, Aneurysmal Disease, Aorta, Thoracic Pathologies | 6 |
| Norman Fixel Institute for Neurological Diseases | Cervical Dystonia, Essential Tremor, Multiple Sclerosis (MS) - Relapsing-remitting | 6 |
| University of Florida - Gainesville | Peripheral Arterial Disease, Acinetobacter Baumannii-calcoaceticus Complex Infection (ABC), Aneurysm Dissecting | 6 |
| University of Florida Shands Hospital | Aortic Aneurysm, Abdominal, Extent IV Thoracoabdominal, Juxtarenal Aortic Aneurysm | 6 |
| Sarkis Clinical Trials | Major Depressive Disorder, Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder | 5 |
| North Florida / South Georgia Veterans Health System | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 4 |
| UF Health at Shands Hospital | Trauma Injury, Acute Blood Loss Anemia, Chronic Anemia | 4 |
| North Florida Regional Medical Center | Coronary Artery Disease, High-Risk Percutaneous Coronary Intervention, Mitral Valve Regurgitation | 3 |
| North Florida/South Georgia Veterans Health System | Androgen Deficiency, Central Nervous System Diseases, Endocrine System Diseases | 3 |
| The Cardiac and Vascular Institute Research Foundation | Chronic Limb-Threatening Ischemia Nos of Native Arteries of Extremities, Coronary Arterial Disease (CAD), Peripheral Arterial Disease | 3 |
| UF Health at the University of Florida | GERD, Hearing Loss, Lung Transplant | 3 |
| University of Florida Clinical Research Center | Duchenne Muscular Dystrophy, Glycogen Storage Disease Type II Infantile Onset, Myotonic Dystrophy Type 1 (DM1) | 3 |
| University of Florida Health Shands Hospital | Confusion, Critical Illness, Delirium | 3 |
| Clinical and Translational Research Building | Aging, Hyperparathyroidism, Mobility | 2 |
| Florida Cancer Specialists | Advanced Non-Small Cell Lung Cancer, Breast Cancer, Breast Neoplasms | 2 |
| Integrative Cardiovasculal Physiology Laboratory, University of Florida | Breast Cancer, Breast Cancer Survivors | 2 |
Active & Upcoming Studies in Gainesville (2026)
Recruiting trials in Gainesville grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (112 active studies)
Cardiovascular (43 active studies)
- A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
- Xenon for Neuroprotection During Post-Cardiac Arrest Syndrome in Comatose Survivors of an Out of Hospital Cardiac Arrest · Phase 3 · Invero Pharma, Inc.
Neurology & pain (41 active studies)
- Kava Aging and Mobility Study · EARLY_Phase 1 · University of Florida
- Effects of Photobiomodulation on Inflammation and Chronic Pain in Knee Osteoarthritis (EPIC-KO) · University of Florida
Diabetes & metabolic (28 active studies)
- PRISE (Personalized Response and Immunologic Surveillance of Endogenous C-Peptide Preservation in New, Recent, and Established Onset Type 1 Diabetes Treated With Human Anti-Thymocyte Globulin [h-ATG]) Study · Phase 3 · University of Florida
- A Study Comparing Continuous Glucose Monitoring Augmented Nutritional Counseling and Standard of Care Treatment Strategies in a Three-Month Nutrition Intervention · University of Florida
Mental health & behavior (14 active studies)
- A Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the Treatment of Schizophrenia and Autism-Related Irritability in Adolescents, Respectively · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder · Phase 2 · AbbVie
Eye & vision (9 active studies)
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
- Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS) · Phase 3 · Adverum Biotechnologies, Inc.
Pediatric (6 active studies)
- A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
- A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
HIV / STI (3 active studies)
Vaccines (1 active study)
Common conditions studied in Gainesville
- Breast Cancer (12 active studies)
- Heart Failure (9 active studies)
- Parkinson Disease (8 active studies)
- Acute Myeloid Leukemia (6 active studies)
- Neuroblastoma (6 active studies)
- Peripheral Arterial Disease (6 active studies)
Leading research sponsors in Gainesville
- University of Florida
- National Cancer Institute (NCI)
- AstraZeneca
- Children's Oncology Group
- VA Office of Research and Development
Frequently asked questions
How many paid clinical trials are currently recruiting in Gainesville?
There are approximately 539 recruiting clinical trials in Gainesville, Florida listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Gainesville pay participants?
Most recruiting trials in Gainesville compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Gainesville?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Gainesville?
The most common conditions under active study in Gainesville include Breast Cancer (12), Heart Failure (9), Parkinson Disease (8), Acute Myeloid Leukemia (6), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Gainesville?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Gainesville on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Gainesville?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Gainesville?
Recruiting research sites in Gainesville include University of Florida, UF Health Cancer Institute - Gainesville, University of Florida Health, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Gainesville right now?
The largest active categories in Gainesville are Cancer & tumors (112), Cardiovascular (43), Neurology & pain (41). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
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