Paid Clinical Trials in Gainesville, FL
As of August 2026, 546 paid clinical trials are recruiting in Gainesville, Florida. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Gainesville offers studies at sites including University of Florida for conditions such as Breast Cancer, Heart Failure, Parkinson Disease, Acute Myeloid Leukemia. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Gainesville
Trials by drug in Gainesville
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Newly added in Gainesville
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
A Study to Investigate the Efficacy and Safety of Apraglutide Compared With Placebo in Adult Participants With Short Bowel Syndrome Associated With Intestinal Failure (SBS-IF)
Cross-System Effects of Acute Intermittent Hypercapnia-Based Interventions in PD
488 clinical trials
A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)
Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
Phase 2 Study to Assess the Safety and Efficacy of ANG003
Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)
A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-1)
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis
LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer
A Study to Evaluate the Optimization of the Cytokine Release Syndrome Profile for Glofitamab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed/Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.
AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions
A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis
BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum Disorder
A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
A Study of ASP3082 in Adults With Advanced Solid Tumors
A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer
Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial
Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder in Pediatric Patients
RELIEF - A Global Prospective Observational Post-Market Study to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain
Pompe Disease Registry Protocol
Fabry Disease Registry & Pregnancy Sub-registry
Top Research Study Locations in Gainesville
Researchers run research studies in Gainesville, FL at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Florida | Parkinson Disease, Breast Cancer, Cancer | 210 |
| UF Health Cancer Institute - Gainesville | Acute Myeloid Leukemia, Metastatic Malignant Solid Neoplasm, Advanced Malignant Solid Neoplasm | 45 |
| University of Florida Health | Acute Pancreatitis, Advanced Solid Tumors, Astrocytoma, Grade IV | 13 |
| North Florida/South Georgia Veterans Health System, Gainesville, FL | Alcohol Use Disorder (AUD), Atherosclerosis, Brain Injury | 11 |
| Malcom Randall Veterans Administration Medical Center | Stage IV Lung Cancer AJCC v8, Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum | 9 |
| University of Florida College of Medicine | Sepsis, Septic Shock, COVID-19, Coronavirus Infections | 9 |
| UF Health | Adult Glioblastoma, Brain Metastases, Cognitive Dysfunction | 7 |
| Vitreo Retinal Associates | Stargardt Disease, Cone Rod Dystrophy, Juvenile Macular Degeneration | 7 |
| UF Health Shands Hospital | Aneurysm of Aorta, Thoracic, Aneurysmal Disease, Aorta, Thoracic Pathologies | 6 |
| Norman Fixel Institute for Neurological Diseases | Cervical Dystonia, Essential Tremor, Essential Tremor (ET) | 6 |
| The Cardiac and Vascular Institute | Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia, Coronary Arterial Disease (CAD) | 6 |
| University of Florida - Gainesville | Peripheral Arterial Disease, Acinetobacter Baumannii-calcoaceticus Complex Infection (ABC), Aneurysm Dissecting | 6 |
| University of Florida Shands Hospital | Aortic Aneurysm, Abdominal, Extent IV Thoracoabdominal, Juxtarenal Aortic Aneurysm | 6 |
| Sarkis Clinical Trials | Major Depressive Disorder, Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder | 5 |
| North Florida / South Georgia Veterans Health System | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 4 |
| UF Health at Shands Hospital | Trauma Injury, Acute Blood Loss Anemia, Chronic Anemia | 4 |
| North Florida Regional Medical Center | Coronary Artery Disease, High-Risk Percutaneous Coronary Intervention, Mitral Valve Regurgitation | 3 |
| North Florida/South Georgia Veterans Health System | Androgen Deficiency, Central Nervous System Diseases, Endocrine System Diseases | 3 |
| The Cardiac and Vascular Institute Research Foundation | Chronic Limb-Threatening Ischemia Nos of Native Arteries of Extremities, Coronary Arterial Disease (CAD), Peripheral Arterial Disease | 3 |
| UF Health at the University of Florida | GERD, Hearing Loss, Lung Transplant | 3 |
| University of Florida Clinical Research Center | Duchenne Muscular Dystrophy, Glycogen Storage Disease Type II Infantile Onset, Myotonic Dystrophy Type 1 (DM1) | 3 |
| University of Florida Gainesville | Femoral Neck Fractures, Hip Fractures, Intertrochanteric Fractures | 3 |
| University of Florida Health Shands Hospital | Confusion, Critical Illness, Delirium | 3 |
| Clinical and Translational Research Building | Aging, Hyperparathyroidism, Mobility | 2 |
| Florida Cancer Specialists | Advanced Non-Small Cell Lung Cancer, Breast Cancer, Breast Neoplasms | 2 |
Active & Upcoming Studies in Gainesville (2026)
Recruiting trials in Gainesville grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (115 active studies)
Cardiovascular (45 active studies)
- CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA) · VA Office of Research and Development
- A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
Neurology & pain (42 active studies)
- Kava Aging and Mobility Study · EARLY_Phase 1 · University of Florida
- Effects of Photobiomodulation on Inflammation and Chronic Pain in Knee Osteoarthritis (EPIC-KO) · University of Florida
Diabetes & metabolic (28 active studies)
- PRISE (Personalized Response and Immunologic Surveillance of Endogenous C-Peptide Preservation in New, Recent, and Established Onset Type 1 Diabetes Treated With Human Anti-Thymocyte Globulin [h-ATG]) Study · Phase 3 · University of Florida
- A Study Comparing Continuous Glucose Monitoring Augmented Nutritional Counseling and Standard of Care Treatment Strategies in a Three-Month Nutrition Intervention · University of Florida
Mental health & behavior (15 active studies)
- A Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the Treatment of Schizophrenia and Autism-Related Irritability in Adolescents, Respectively · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder · Phase 2 · AbbVie
Eye & vision (9 active studies)
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
- Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS) · Phase 3 · Adverum Biotechnologies, Inc.
Pediatric (6 active studies)
- A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
- A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
HIV / STI (3 active studies)
Vaccines (1 active study)
Common conditions studied in Gainesville
- Breast Cancer (12 active studies)
- Heart Failure (10 active studies)
- Parkinson Disease (10 active studies)
- Acute Myeloid Leukemia (6 active studies)
- Neuroblastoma (6 active studies)
- Peripheral Arterial Disease (6 active studies)
Leading research sponsors in Gainesville
- University of Florida
- National Cancer Institute (NCI)
- AstraZeneca
- VA Office of Research and Development
- Children's Oncology Group
Frequently asked questions
How many paid clinical trials are currently recruiting in Gainesville?
There are approximately 546 recruiting clinical trials in Gainesville, Florida listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Gainesville pay participants?
Most recruiting trials in Gainesville compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Gainesville?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Gainesville?
The most common conditions under active study in Gainesville include Breast Cancer (12), Heart Failure (10), Parkinson Disease (10), Acute Myeloid Leukemia (6), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Gainesville?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Gainesville on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Gainesville?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Gainesville?
Recruiting research sites in Gainesville include University of Florida, UF Health Cancer Institute - Gainesville, University of Florida Health, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Gainesville right now?
The largest active categories in Gainesville are Cancer & tumors (115), Cardiovascular (45), Neurology & pain (42). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.