Paid Clinical Trials in Gainesville, FL
As of September 2026, 548 paid clinical trials are recruiting in Gainesville, Florida. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Gainesville offers studies at sites including University of Florida for conditions such as Breast Cancer, Heart Failure, Parkinson Disease, Acute Myeloid Leukemia. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Gainesville
Trials by drug in Gainesville
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Newly added in Gainesville
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Evaluating VM100 Nutritional Supplement for Improving Quality of Life in Duchenne Muscular Dystrophy Patients
A Trial of the Efficacy and Safety of Fixed Doses of SEP-363856 in Adults With Generalized Anxiety Disorder
A Study to Test the Effects of Centanafadine in Adults With Attention-deficit/Hyperactivity Disorder and Emotional Dysregulation
Respiratory, Limb Muscle Properties, and Physical Performance in Adult Lung Transplant Recipients
A Study to Investigate the Efficacy and Safety of Apraglutide Compared With Placebo in Adult Participants With Short Bowel Syndrome Associated With Intestinal Failure (SBS-IF)
485 clinical trials
A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)
Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
Phase 2 Study to Assess the Safety and Efficacy of ANG003
Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)
Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease
A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia
LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression)
Evaluate Optimization of CRS Profile for Glofit Monotherapy and Glofit+GemOx in R/R Aggressive B-NHL
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Children With ADHD
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II
A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-1)
A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease
SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
RELIEF - A Global Prospective Observational Post-Market Study to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain
Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum Disorder
AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions
A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis
Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder in Pediatric Patients
Top Research Study Locations in Gainesville
Researchers run research studies in Gainesville, FL at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Florida | Parkinson Disease, Breast Cancer, Duchenne Muscular Dystrophy | 208 |
| UF Health Cancer Institute - Gainesville | Acute Myeloid Leukemia, Metastatic Malignant Solid Neoplasm, Advanced Malignant Solid Neoplasm | 44 |
| University of Florida Health | Acute Pancreatitis, Advanced Solid Tumors, Astrocytoma, Grade IV | 12 |
| North Florida/South Georgia Veterans Health System, Gainesville, FL | Alcohol Use Disorder (AUD), Atherosclerosis, Brain Injury | 11 |
| Malcom Randall Veterans Administration Medical Center | Lung Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8 | 10 |
| UF Health Shands Hospital | Aneurysm of Aorta, Thoracic, Aneurysmal Disease, Aorta, Thoracic Pathologies | 7 |
| University of Florida College of Medicine | COVID-19, Coronavirus Infections, Danon Disease | 7 |
| Vitreo Retinal Associates | Stargardt Disease, Cone Rod Dystrophy, Juvenile Macular Degeneration | 7 |
| Norman Fixel Institute for Neurological Diseases | Cervical Dystonia, Essential Tremor, Essential Tremor (ET) | 6 |
| The Cardiac and Vascular Institute | Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia, Coronary Arterial Disease (CAD) | 6 |
| UF Health | Adult Glioblastoma, Brain Metastases, Compartment Syndromes | 6 |
| University of Florida - Gainesville | Peripheral Arterial Disease, Acinetobacter Baumannii-calcoaceticus Complex Infection (ABC), Aneurysm Dissecting | 6 |
| University of Florida Shands Hospital | Aortic Aneurysm, Abdominal, Extent IV Thoracoabdominal, Juxtarenal Aortic Aneurysm | 6 |
| Sarkis Clinical Trials | Major Depressive Disorder, Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder | 5 |
| North Florida / South Georgia Veterans Health System | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 4 |
| UF Health at Shands Hospital | Trauma Injury, Acute Blood Loss Anemia, Chronic Anemia | 4 |
| University of Florida Clinical Research Center | Duchenne Muscular Dystrophy, Glycogen Storage Disease Type II Infantile Onset, Hypothyroidism | 4 |
| North Florida Regional Medical Center | Coronary Artery Disease, High-Risk Percutaneous Coronary Intervention, Mitral Valve Regurgitation | 3 |
| North Florida/South Georgia Veterans Health System | Androgen Deficiency, Central Nervous System Diseases, Endocrine System Diseases | 3 |
| The Cardiac and Vascular Institute Research Foundation | Chronic Limb-Threatening Ischemia Nos of Native Arteries of Extremities, Coronary Arterial Disease (CAD), Peripheral Arterial Disease | 3 |
| UF Health at the University of Florida | GERD, Hearing Loss, Lung Transplant | 3 |
| University of Florida Gainesville | Femoral Neck Fractures, Hip Fractures, Intertrochanteric Fractures | 3 |
| University of Florida Health Shands Hospital | Confusion, Critical Illness, Delirium | 3 |
| Clinical and Translational Research Building | Aging, Hyperparathyroidism, Mobility | 2 |
| Integrative Cardiovasculal Physiology Laboratory, University of Florida | Breast Cancer, Breast Cancer Survivors | 2 |
Active & Upcoming Studies in Gainesville (2026)
Recruiting trials in Gainesville grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (114 active studies)
Cardiovascular (47 active studies)
- CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA) · VA Office of Research and Development
- A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
Neurology & pain (43 active studies)
- Kava Aging and Mobility Study · EARLY_Phase 1 · University of Florida
- COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE" · Phase 3 · Yale University
Diabetes & metabolic (26 active studies)
- Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS) · Phase 3 · Eli Lilly and Company
- PRISE (Personalized Response and Immunologic Surveillance of Endogenous C-Peptide Preservation in New, Recent, and Established Onset Type 1 Diabetes Treated With Human Anti-Thymocyte Globulin [h-ATG]) Study · Phase 3 · University of Florida
Mental health & behavior (16 active studies)
- Deconstructing Maternal Burdens: Doulas and the Community Unite for Health · University of Florida
- A Trial of the Efficacy and Safety of Fixed Doses of SEP-363856 in Adults With Generalized Anxiety Disorder · Phase 3 · Otsuka Pharmaceutical Development & Commercialization, Inc.
Eye & vision (8 active studies)
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
- Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS) · Phase 3 · Adverum Biotechnologies, Inc.
Pediatric (8 active studies)
- Evaluating VM100 Nutritional Supplement for Improving Quality of Life in Duchenne Muscular Dystrophy Patients · University of Florida
- A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
Vaccines (1 active study)
HIV / STI (1 active study)
Common conditions studied in Gainesville
- Breast Cancer (10 active studies)
- Heart Failure (10 active studies)
- Parkinson Disease (10 active studies)
- Acute Myeloid Leukemia (7 active studies)
- Duchenne Muscular Dystrophy (7 active studies)
- Neuroblastoma (6 active studies)
Leading research sponsors in Gainesville
- University of Florida
- National Cancer Institute (NCI)
- VA Office of Research and Development
- AstraZeneca
- Children's Oncology Group
Frequently asked questions
How many paid clinical trials are currently recruiting in Gainesville?
There are approximately 548 recruiting clinical trials in Gainesville, Florida listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Gainesville pay participants?
Most recruiting trials in Gainesville compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Gainesville?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Gainesville?
The most common conditions under active study in Gainesville include Breast Cancer (10), Heart Failure (10), Parkinson Disease (10), Acute Myeloid Leukemia (7), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Gainesville?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Gainesville on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Gainesville?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Gainesville?
Recruiting research sites in Gainesville include University of Florida, UF Health Cancer Institute - Gainesville, University of Florida Health, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Gainesville right now?
The largest active categories in Gainesville are Cancer & tumors (114), Cardiovascular (47), Neurology & pain (43). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.