Paid Clinical Trials in Gainesville, FL

As of August 2026, 546 paid clinical trials are recruiting in Gainesville, Florida. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 10, 2026.

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488 clinical trials

A Study Assessing KB407 for the Treatment of Cystic Fibrosis

for Cystic Fibrosis

Sites in Gainesville +5 more locations

Sponsor: Krystal Biotech, Inc.

Sex: All·Age: 18+

Code: NCT05504837·Phase 1·Recruiting·Listed Aug 2022

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Safety and Tolerability of Subretinally Injected OPGx-BEST1 in Patients With Best Vitelliform Macular Dystrophy (BVMD) or Autosomal-Recessive Bestrophinopathy (ARB)

for ARB

Sites in Gainesville +3 more locations

Sponsor: Opus Genetics, Inc

Sex: All·Age: 18+

Code: NCT07185256·Phase 1, Phase 2·Recruiting·Listed Sep 2025

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A Long-Term Study of JNT-517 in Participants With Phenylketonuria

for Phenylketonuria (PKU)

Sites in Gainesville, Tampa +6 more locations

Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.

Sex: All·Age: 4+

Code: NCT06628128·Phase 3·Recruiting·Listed Oct 2024

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HLA Demographics Study in Adults With Type 1 Diabetes

for Diabetes Mellitus, Type I

Sites in Gainesville +4 more locations

Sponsor: GentiBio, Inc

Sex: All·Age: 18 - 55

Code: NCT06860516·Recruiting·Listed Mar 2025

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A Study to Learn More About the Long-Term Safety of BIIB141 (Omaveloxolone) in Participants With Friedreich's Ataxia Who Are Prescribed it by Their Own Doctors

for Friedreich Ataxia

Sites in Gainesville +3 more locations

Sponsor: Biogen

Sex: All·Age: 16+

Code: NCT06623890·Recruiting·Listed Oct 2024

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Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-101 in Participants With Myotonic Dystrophy Type 1

for Myotonic Dystrophy Type 1 (DM1)

Sites in Gainesville +7 more locations

Sponsor: Dyne Therapeutics

Sex: All·Age: 18 - 65

Code: NCT05481879·Phase 1, Phase 2·Recruiting·Listed Aug 2022

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S-531011 as Monotherapy and in Combination With an Immune Checkpoint Inhibitor in Advanced or Metastatic Solid Tumors

for Solid Tumors

Sites in Gainesville +2 more locations

Sponsor: Shionogi

Sex: All·Age: 18+

Code: NCT05101070·Phase 1, Phase 2·Recruiting·Listed Nov 2021

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Regeneration of Acutely Injured Nerves With Temporary Electrical Stimulation

for Nerve Injury

Sites in Gainesville, Orlando +2 more locations

Sponsor: Epineuron Technologies Inc.

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05721261·Recruiting·Listed Feb 2023

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Study of STM-416p Administered to Patients Undergoing Radical Prostatectomy

for Prostate Cancer

Sites in Gainesville +1 more location

Sponsor: SURGE Therapeutics

Sex: Male·Age: 18+

Code: NCT06450106·Phase 1·Recruiting·Listed Jun 2024

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Study of ATX-01 in Participants With DM1

for Myotonic Dystrophy 1

Sites in Gainesville +4 more locations

Sponsor: ARTHEx Biotech S.L.

Sex: All·Age: 18 - 64

Code: NCT06300307·Phase 1, Phase 2·Recruiting·Listed Mar 2024

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Multicenter Symphony IL-6 Monitoring Sepsis ICU Validation Study

for Sepsis, Septic Shock

Sites in Gainesville +4 more locations

Sponsor: Bluejay Diagnostics, Inc.

Sex: All·Age: 22+

Code: NCT06654895·Recruiting·Listed Oct 2024

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A Study to Evaluate the Safety, Efficacy, PK, PD and Immunogenicity of Cipaglucosidase Alfa/Miglustat in IOPD Subjects Aged 0 to <18

for Glycogen Storage Disease Type II Infantile Onset

Sites in Gainesville +5 more locations

Sponsor: Amicus Therapeutics

Sex: All·Age: Up to 17

Code: NCT04808505·Phase 3·Recruiting·Listed Mar 2021

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Prescreening Study to Identify Potential Stargardt Participants for ACDN-01 Clinical Trials (STARPATH)

for Stargardt Disease

Sites in Gainesville +7 more locations

Sponsor: Ascidian Therapeutics, Inc

Sex: All·Age: 5+

Code: NCT06445322·Recruiting·Listed Jun 2024

Apply to this trial

Atypical Hemolytic-Uremic Syndrome (aHUS) Registry

for Atypical Hemolytic-Uremic Syndrome

Sites in Gainesville +5 more locations

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: All ages

Code: NCT01522183·Recruiting·Listed Jan 2012

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A Study to Evaluate Ferumoxytol for the Treatment of Iron Deficiency Anemia (IDA) in Pediatric Subjects

for Iron Deficiency Anemia

Sites in Gainesville, Miami +4 more locations

Sponsor: AMAG Pharmaceuticals, Inc.

Sex: All·Age: 2 - 17

Code: NCT03893045·Phase 3·Recruiting·Listed Mar 2019

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Early Feasibility Study of "HyperQureTM RDN System", Laparoscopic Renal Denervation Therapy, in Patients With Resistant Hypertension

for Resistant Hypertension

Sites in Gainesville +4 more locations

Sponsor: DeepQure Inc.

Sex: All·Age: 22 - 80

Code: NCT06526858·Recruiting·Listed Jul 2024

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A Study to Evaluate the SENSE Device's Ability to Detect TBI

for Traumatic Brain Injury

Sites in Gainesville +5 more locations

Sponsor: Sense Diagnostics, LLC

Sex: All·Age: 22+·Accepts healthy volunteers

Code: NCT06828107·Recruiting·Listed Feb 2025

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Safety and Device Performance of the Uriprene® Degradable Temporary Ureteral Stent Following Uncomplicated Ureteroscopy

for Ureteral Diseases

Sites in Gainesville +3 more locations

Sponsor: Adva-Tec

Sex: All·Age: 21 - 80

Code: NCT04565795·Recruiting·Listed Sep 2020

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A Study of KB408 for the Treatment of Alpha-1 Antitrypsin Deficiency

for Alpha 1-Antitrypsin Deficiency

Sites in Gainesville +2 more locations

Sponsor: Krystal Biotech, Inc.

Sex: All·Age: 18 - 70

Code: NCT06049082·Phase 1·Recruiting·Listed Sep 2023

Apply to this trial

ProACT Post-Approval Study

for Stress Urinary Incontinence

Sites in Gainesville +5 more locations

Sponsor: Uromedica

Sex: Male·Age: 50+·Accepts healthy volunteers

Code: NCT03767595·Recruiting·Listed Dec 2018

Apply to this trial

Hearts on Fire: Targeting Inflammation in Heart Failure With Preserved Ejection Fraction

for Heart Failure With Preserved Ejection Fraction (HFPEF)

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 85

Code: NCT07634640·EARLY_Phase 1·Recruiting·Listed Jun 2026

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uSafeUS+ App Pilot Testing

for Alcohol Consumption

Sites in Gainesville +1 more location

Sponsor: University of Florida

Sex: All·Age: 18 - 25·Accepts healthy volunteers

Code: NCT07557745·Recruiting·Listed Apr 2026

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RNA-lipid Particle (RNA-LP) Vaccines for Recurrent/Progressive Medulloblastoma (MB)

for Recurrent Medulloblastoma

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 4 - 39

Code: NCT07492316·Phase 1·Recruiting·Listed Mar 2026

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Evaluation of Circles of Safety

for Child Abuse Sexual

1 location in Gainesville

Sponsor: Center for Violence Prevention Research Inc

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07526142·Recruiting·Listed Apr 2026

Apply to this trial

Cranberry Polyphenols and Stress Resilience During Multitasking in Healthy Adults

for Stress Response

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 30 - 55·Accepts healthy volunteers

Code: NCT07453537·Recruiting·Listed Mar 2026

Apply to this trial

Supraspinatus Tendon Acute Effects After Two Exercise Exposures: a Crossover Randomized Trial.

for Shoulder Pain

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 45·Accepts healthy volunteers

Code: NCT07489937·Recruiting·Listed Mar 2026

Apply to this trial

Clinical Safety Guidelines for Managing Distal Shoe Complications

for Premature Loss of Primary Molars

2 locations in Gainesville

Sponsor: University of Florida

Sex: All·Age: 3 - 9

Code: NCT07410442·Recruiting·Listed Feb 2026

Apply to this trial

Safety and Tolerability of Patterned Stimulation for DBS in the Home Setting

for Parkinson Disease

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 80

Code: NCT07410598·Recruiting·Listed Feb 2026

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Treating Spinal Cord Injury With Early Normobaric Hyperoxia

for Traumatic Spinal Cord Injuries

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 85

Code: NCT07465302·Phase 2·Recruiting·Listed Mar 2026

Apply to this trial

Rehab and Mechanical Ventilation

for Inspiratory Strength Training (IST)

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 25 - 80·Accepts healthy volunteers

Code: NCT07427121·Recruiting·Listed Feb 2026

Apply to this trial

Magnetoencephalography (MEG) Pilot Study

for Essential Tremor

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 50 - 84

Code: NCT07446192·Recruiting·Listed Mar 2026

Apply to this trial

Project HOPEFUL: A PN-RCT With Implementation Science

for Older Adults (50-90 Years)

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT07475039·Recruiting·Listed Mar 2026

Apply to this trial

PREcision MEDicine In Achalasia (PREMEDIA) - Cohort

for Type III Achalasia

Sites in Gainesville, Orlando +13 more locations

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07293689·Recruiting·Listed Dec 2025

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PREcision MEDicine In Achalasia (PREMEDIA)

for Type I Achalasia

Sites in Gainesville, Orlando +13 more locations

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07293650·Phase 3·Recruiting·Listed Dec 2025

Apply to this trial

Telehealth-Adapted Compensatory Training and Intervention for Cognition

for MCI

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 65 - 84

Code: NCT07366346·Recruiting·Listed Jan 2026

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Interposed Nucleus aDBS for Ataxia

for Spinocerebellar Ataxia (SCA)

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 21 - 89

Code: NCT07325487·Recruiting·Listed Jan 2026

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Improving Cervical Cancer Prevention Among Women Living With Chronic Conditions.

for Diabetes

1 location in Gainesville

Sponsor: University of Florida

Sex: Female·Age: 25+·Accepts healthy volunteers

Code: NCT07351110·Recruiting·Listed Jan 2026

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Prefrontal Theta Burst Stimulation to Improve Cognitive Impairment After ICU Delirium

for Post-delirium Cognitive Impairment

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 50 - 75

Code: NCT07452939·Recruiting·Listed Mar 2026

Apply to this trial

Colorectal Cancer Prevention Research Study: Eat Right, Screen Right

for Colorectal Cancer Prevention

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07393906·Recruiting·Listed Feb 2026

Apply to this trial

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

for Stage III Colon Cancer

Sites in Gainesville, Jacksonville +913 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021

Apply to this trial