Paid Clinical Trials in Greenville, NC

As of September 2026, 156 paid clinical trials are recruiting in Greenville, North Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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144 clinical trials

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Optimizing the AYA Survivors' Coping and Emotional Needs Toolkit

for Depression

Sites in Greenville & Winston-Salem

Sponsor: East Carolina University

Sex: All·Age: 15 - 39

Code: NCT07173205·Recruiting·Listed Sep 2025

Apply to this trial

Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)

for Sickle Cell Trait

Sites in Greenville, Durham +8 more locations

Sponsor: National Alliance for Sickle Cell Centers

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06071377·Recruiting·Listed Oct 2023

Apply to this trial

SEVENFACT® for Bleeding Events in Hemophilia With Inhibitors

for Hemophilia A With Inhibitor

Sites in Greenville +16 more locations

Sponsor: American Thrombosis and Hemostasis Network

Sex: All·Age: 12 - 100

Code: NCT04647227·Phase 4·Recruiting·Listed Nov 2020

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Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma

for Cutaneous Melanoma, Stage II

Sites in Greenville, Durham +128 more locations

Sponsor: Melanoma and Skin Cancer Trials Limited

Sex: All·Age: 18+

Code: NCT03860883·Recruiting·Listed Mar 2019

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Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain

for Pain

Sites in Greenville, Durham +12 more locations

Sponsor: University of Pittsburgh

Sex: All·Age: 16 - 30

Code: NCT06374238·Recruiting·Listed Apr 2024

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A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists

for Heart Failure

Drug: Finerenone

Sites in Greenville, Charlotte +52 more locations

Sponsor: Colorado Prevention Center

Sex: All·Age: 18+

Code: NCT06033950·Phase 3·Recruiting·Listed Sep 2023

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Developing a Digital Aid to Improve ICD Decisions

for Heart Failure and Reduced Ejection Fraction

Sites in Greenville +1 more location

Sponsor: Stanford University

Sex: All·Age: 60+

Code: NCT07084142·Recruiting·Listed Jul 2025

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Metabolic Inflexibility is Related to Elevated Muscle Anaerobic Glycolysis

for Metabolic Inflexibility

1 location in Greenville

Sponsor: East Carolina University

Sex: All·Age: 18 - 50

Code: NCT04320264·Recruiting·Listed Mar 2020

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A Study to Investigate Canvuparatide Compared With Placebo in Adult Patients With Hypoparathyroidism

for Hypoparathyroidism

Sites in Greenville +11 more locations

Sponsor: MBX Biosciences

Sex: All·Age: 18+

Code: NCT07699471·Phase 3·Recruiting·Listed Jul 2026

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Study to Determine if BHV-1300 is Effective and Safe in Adults With Graves' Disease

for Graves Disease

Sites in Greenville, Morehead City +47 more locations

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18 - 70

Code: NCT07661056·Phase 3·Recruiting·Listed Jun 2026

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A Study to Investigate Abdominal Symptoms With Camlipixant Compared With Placebo in Adults With Irritable Bowel Syndrome - Diarrhea (IBS-D) and Irritable Bowel Syndrome - Mixed (IBS-M)

for Irritable Bowel Syndrome

Sites in Greenville, Rocky Mount +112 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18 - 80

Code: NCT07519395·Phase 2·Recruiting·Listed Apr 2026

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A Phase 3 Randomized Clinical Trial to Investigate the Safety and Efficacy of Palopegteriparatide at Doses Greater Than 30 μg/Day in Adult Participants With Hypoparathyroidism

for Hypoparathyroidism

Drug: Palopegteriparatide

Sites in Greenville +6 more locations

Sponsor: Ascendis Pharma Bone Diseases A/S

Sex: All·Age: 18+

Code: NCT07081997·Phase 3·Recruiting·Listed Jul 2025

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Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

for Non-Small Cell Lung Cancer

Drug: Rilvegostomig

Sites in Greenville, Salisbury +47 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06357533·Phase 3·Recruiting·Listed Apr 2024

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Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

for Endometrial Carcinoma

Sites in Greenville, Raleigh +325 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT05256225·Phase 3·Recruiting·Listed Feb 2022

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A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)

for Heart Failure

Drug: Finerenone

Sites in Greenville, Morrisville +44 more locations

Sponsor: Colorado Prevention Center

Sex: All·Age: 18+

Code: NCT06024746·Phase 3·Recruiting·Listed Sep 2023

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A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

for Chronic Kidney Disease and Hypertension

Drug: Dapagliflozin

Sites in Greenville, Kinston +115 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06742723·Phase 3·Recruiting·Listed Dec 2024

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A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

for COPD (Chronic Obstructive Pulmonary Disease)

Sites in Greenville, Morehead City +132 more locations

Sponsor: AstraZeneca

Sex: All·Age: 40 - 80

Code: NCT06283966·Phase 3·Recruiting·Listed Feb 2024

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Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

for Endometrial Cancer

Sites in Greenville, Pinehurst +65 more locations

Sponsor: AstraZeneca

Sex: Female·Age: 18+

Code: NCT07044336·Phase 3·Recruiting·Listed Jun 2025

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Study of BHV-1300 in Graves' Disease

for Graves Disease

Sites in Greenville +9 more locations

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18 - 65

Code: NCT06980649·Phase 1·Recruiting·Listed May 2025

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Global Trial in APG2575 for Patients With CLL/SLL

for CLL/SLL

Sites in Greenville +10 more locations

Sponsor: Ascentage Pharma Group Inc.

Sex: All·Age: 18 - 99

Code: NCT06104566·Phase 3·Recruiting·Listed Oct 2023

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A Study of XTMAB-16 in Patients With Pulmonary Sarcoidosis

for Pulmonary Sarcoidosis

Sites in Greenville +13 more locations

Sponsor: Xentria, Inc.

Sex: All·Age: 18 - 80

Code: NCT05890729·Phase 1, Phase 2·Recruiting·Listed Jun 2023

Apply to this trial