Paid Clinical Trials in Honolulu, HI
As of June 2026, 220 paid clinical trials are recruiting in Honolulu, Hawaii. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Honolulu offers studies at sites including Kapiolani Medical Center for Women and Children for conditions such as Malignant Solid Neoplasm, Breast Cancer, Neuroblastoma, Acute Myeloid Leukemia. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Honolulu
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Honolulu has approximately 220 recruiting research studies across a wide range of therapeutic areas. Hawaii hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.
Top Research Study Locations in Honolulu
Researchers run research studies in Honolulu, HI at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Kapiolani Medical Center for Women and Children | Neuroblastoma, Malignant Solid Neoplasm, Acute Myeloid Leukemia | 72 |
| Queen's Medical Center | Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | 45 |
| Hawaii Cancer Care Inc - Waterfront Plaza | Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8, Acute Myeloid Leukemia | 42 |
| Queen's Cancer Center - Kuakini | Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | 40 |
| Queen's Cancer Cenrer - POB I | Stage IV Lung Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Lung Non-Small Cell Carcinoma | 38 |
| Straub Clinic and Hospital | Acute Myeloid Leukemia, Malignant Solid Neoplasm, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm | 38 |
| University of Hawaii Cancer Center | Anatomic Stage IV Breast Cancer AJCC v8, Breast Cancer, Extensive Stage Lung Small Cell Carcinoma | 37 |
| Kaiser Permanente Moanalua Medical Center | Stage IIIB Lung Cancer AJCC v8, Breast Cancer, Ovarian Carcinoma | 33 |
| The Cancer Center of Hawaii-Liliha | Breast Cancer, Extensive Stage Lung Small Cell Carcinoma, Malignant Solid Neoplasm | 25 |
| Kuakini Medical Center | Breast Cancer, Malignant Solid Neoplasm, Ovarian Carcinoma | 21 |
| Tripler Army Medical Center | Malignant Solid Neoplasm, ACDF Surgery, Adrenal Gland Pheochromocytoma | 16 |
| Hawaii Pacific Neuroscience | Focal Epilepsy, Alzheimers Disease, Lewy Body Dementia Psychosis | 14 |
| The Queen's Medical Center | Heart Failure, Intracerebral Hemorrhage, Methamphetamine Use Disorder | 13 |
| Hawaii Diagnostic Radiology Services LLC | Breast Cancer, Malignant Solid Neoplasm, Advanced Esophageal Adenocarcinoma | 10 |
| Hawaii Cancer Care Inc-Liliha | Anatomic Stage IV Breast Cancer AJCC v8, B Acute Lymphoblastic Leukemia, Cardiotoxicity | 9 |
| Island Urology | Anatomic Stage IV Breast Cancer AJCC v8, B Acute Lymphoblastic Leukemia, Cardiotoxicity | 7 |
| Pacific Diabetes & Endocrine Center | Obesity, Overweight, Cardiovascular Diseases | 4 |
| East-West Medical Research Institute | Healthy Adults, Obesity, Obesity or Overweight | 3 |
| Hawaii Cancer Care | Chemotherapy Induced Peripheral Neuropathy (CIPN), Early Breast Cancer, Non-Small Cell Lung Cancer | 3 |
| Hawaii Pacific Neuroscience LLC | Alzheimer's Disease, Generalized Myasthenia Gravis, Secondary Progressive Multiple Sclerosis (SPMS) | 3 |
| Kapi'olani Medical Center for Women & Children | Acute Respiratory Distress Syndrome, Death; Neonatal, Extracorporeal Membrane Oxygenation | 3 |
| Kapi'olani Medical Center for Women and Children | Acute Myeloid Leukemia, Glioma, H3 K27M | 3 |
| University of Hawai'i Cancer Center | Gestational Diabetes Mellitus (GDM), Health, Health Promotion | 3 |
| University of Hawaii | Contraception, Alzheimer Disease, Dementia | 3 |
| Clinical Study Site | Chronic Inflammatory Demyelinating Polyneuropathy, Multifocal Motor Neuropathy | 2 |
Active & Upcoming Studies in Honolulu (2026)
Recruiting trials in Honolulu grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (102 active studies)
- Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas · Phase 1, Phase 2 · Milton S. Hershey Medical Center
- Ipilimumab and Nivolumab With SBRT in Locally Advanced Hepatocellular Cancer · Phase 1 · University of Hawaii
Diabetes & metabolic (17 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- To Test the Effectiveness and Implementation Approach of a 3-month PILI Pasifika Program Lifestyle Program With Components of Social Determinants of Health Activities in Real-world Settings (Clinical and Non-clinical Settings) Across 3 Years · University of Hawaii
Neurology & pain (17 active studies)
- Mobile Health Dietary Intervention for Stroke Survivors With Prediabetes or Type 2 Diabetes · University of Hawaii
- A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis · Phase 3 · Novartis Pharmaceuticals
Cardiovascular (15 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- To Test the Effectiveness and Implementation Approach of a 3-month PILI Pasifika Program Lifestyle Program With Components of Social Determinants of Health Activities in Real-world Settings (Clinical and Non-clinical Settings) Across 3 Years · University of Hawaii
Pediatric (3 active studies)
- InfasurfAero™ Versus Sham Treatment in Preterm Newborns With RDS · Phase 3 · ONY
- Comparing a Team-Based Approach to Standard Well-Child Visits To Improve Preventive Care Services · Seattle Children's Hospital
HIV / STI (2 active studies)
- Effects of Tirzepatide on Weight Loss and Chronic Inflammation in People With HIV · Phase 2 · University of Hawaii
- Assessing Acceptability and Feasibiity of STI Self-swab Testing, to be Offered at the Time of Telemed Medication Abortion Provision · Queen's Medical Center
Mental health & behavior (2 active studies)
- Quit-Smoking Study for Native Hawaiians · University of Hawaii
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
Vaccines (1 active study)
Common conditions studied in Honolulu
- Malignant Solid Neoplasm (9 active studies). Recruiting Malignant Solid Neoplasm studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Breast Cancer (8 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Neuroblastoma (8 active studies). Recruiting Neuroblastoma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Acute Myeloid Leukemia (6 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Cancer (5 active studies). Recruiting Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Hypertension (5 active studies). Hypertension research tests new antihypertensive drug classes, renal denervation devices, and fixed-dose combinations for resistant disease.
Leading research sponsors in Honolulu
- National Cancer Institute (NCI)
- Children's Oncology Group
- NRG Oncology
- University of Hawaii
- SWOG Cancer Research Network
Local regulations and guidelines
Clinical trials in Hawaii are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Hawaii research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Honolulu. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Honolulu
Hipa.ai aggregates every recruiting study in Honolulu from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Honolulu?
There are approximately 220 recruiting clinical trials in Honolulu, Hawaii listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Honolulu pay participants?
Most recruiting trials in Honolulu compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Honolulu?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Honolulu?
The most common conditions under active study in Honolulu include Malignant Solid Neoplasm (9), Breast Cancer (8), Neuroblastoma (8), Acute Myeloid Leukemia (6), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Honolulu?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Honolulu on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Honolulu?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Honolulu?
Recruiting research sites in Honolulu include Kapiolani Medical Center for Women and Children, Queen's Medical Center, Hawaii Cancer Care Inc - Waterfront Plaza, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Honolulu right now?
The largest active categories in Honolulu are Cancer & tumors (102), Diabetes & metabolic (17), Neurology & pain (17). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.