Paid Clinical Trials in Honolulu, HI
As of August 2026, 186 paid clinical trials are recruiting in Honolulu, Hawaii. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Honolulu offers studies at sites including Kapiolani Medical Center for Women and Children for conditions such as Malignant Solid Neoplasm, Neuroblastoma, Acute Myeloid Leukemia, Obesity. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Honolulu
Trials by drug in Honolulu
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Newly added in Honolulu
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
163 clinical trials
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis
A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
Phase IIIb Study of Ribociclib + ET in Early Breast Cancer
A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Episodic Migraine
A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic Migraine
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer
Phase 2, Efficacy and Safety Study of ACP-204 in Lewy Body Dementia Psychosis
A Study to Test the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures
A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy
A Study to Evaluate the Efficacy and Safety of DNTH103 in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CAPTIVATE)
GEMINI-NSCLC: NSCLC Biomarker Study
A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants
A Phase 2 Study to Evaluate Povetacicept in Adults With Generalized Myasthenia Gravis
A Study to Learn About mRNA Vaccines Against Influenza in Adults
A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease
Study of Trastuzumab Deruxtecan, Pembrolizumab, and Platinum-based Chemotherapy in First-line HER2 Overexpressing Non-small Cell Lung Cancer
The Lilac Device Trial - IMPACT: A Clinical Investigation on IMproving Peripheral Neuropathy Induced by Chemotherapy With Advanced Compression Technology - A Safety and Efficacy Study
Assessment of Support With Impella® Best Practices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics And Pharmacodynamics of SIF001 in Healthy Subjects and in Epilepsy Patients
A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer
Top Research Study Locations in Honolulu
Researchers run research studies in Honolulu, HI at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Kapiolani Medical Center for Women and Children | Neuroblastoma, Malignant Solid Neoplasm, Acute Myeloid Leukemia | 60 |
| Hawaii Cancer Care Inc - Waterfront Plaza | Lung Non-Small Cell Carcinoma, Acute Myeloid Leukemia, Anatomic Stage IV Breast Cancer AJCC v8 | 29 |
| Queen's Medical Center | Lung Non-Small Cell Carcinoma, Anatomic Stage IV Breast Cancer AJCC v8, Stage IV Lung Cancer AJCC v8 | 28 |
| Kaiser Permanente Moanalua Medical Center | Lung Non-Small Cell Carcinoma, Ovarian Carcinoma, Stage IIIB Lung Cancer AJCC v8 | 28 |
| Straub Clinic and Hospital | Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy | 27 |
| Queen's Cancer Center - Kuakini | Lung Non-Small Cell Carcinoma, Anatomic Stage IV Breast Cancer AJCC v8, Stage IV Lung Cancer AJCC v8 | 26 |
| Queen's Cancer Cenrer - POB I | Anatomic Stage IV Breast Cancer AJCC v8, Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8 | 25 |
| University of Hawaii Cancer Center | Anatomic Stage IV Breast Cancer AJCC v8, Breast Cancer, Metastatic Malignant Solid Neoplasm | 23 |
| Tripler Army Medical Center | Malignant Solid Neoplasm, ACDF Surgery, Anatomic Stage I Breast Cancer AJCC v8 | 13 |
| Hawaii Pacific Neuroscience | Focal Epilepsy, Alzheimers Disease, Lewy Body Dementia Psychosis | 12 |
| Kuakini Medical Center | Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma | 10 |
| The Queen's Medical Center | Intracerebral Hemorrhage, Methamphetamine Use Disorder, Aortic Valve Disease | 10 |
| Hawaii Diagnostic Radiology Services LLC | Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma | 7 |
| East-West Medical Research Institute | COVID-19 Vaccines, Healthy Adults, Hypercholesterolemia | 5 |
| The Cancer Center of Hawaii-Liliha | Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 5 |
| Hawaii Cancer Care | Chemotherapy Induced Peripheral Neuropathy (CIPN), Early Breast Cancer, Non-Small Cell Lung Cancer | 3 |
| University of Hawai'i Cancer Center | Gestational Diabetes Mellitus (GDM), Health, Health Promotion | 3 |
| University of Hawaii | Alzheimer Disease, Contraception, Dementia | 3 |
| Clinical Study Site | Chronic Inflammatory Demyelinating Polyneuropathy, Multifocal Motor Neuropathy | 2 |
| Clinical Trial Site | Breast Cancer, ER Positive Breast Cancer, HER2 Negative Breast Carcinoma | 2 |
| Hawaii Pacific Neuroscience LLC | Alzheimer's Disease, Secondary Progressive Multiple Sclerosis (SPMS) | 2 |
| Hawaii Pacific Neuroscience, Comprehensive Epilepsy Center | Epilepsy, Healthy Volunteer, Primary Generalized Tonic-Clonic Seizures | 2 |
| Hawaii Pacific Neuroscience, Merz Investigational | Chronic Migraine, Episodic Migraine | 2 |
| Kapi'olani Medical Center for Women & Children | Death; Neonatal, Intubation Complication, Relapsed/Refractory Locally Advanced or Metastatic Breast Cancer and Triple Negative Breast Cancer | 2 |
| Kula no nā Po'e Hawai'i | Dyslipidemias, Hypertension, Overweight and Obesity | 2 |
Active & Upcoming Studies in Honolulu (2026)
Recruiting trials in Honolulu grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (79 active studies)
- Study of Izalontamab Brengitecan (BMS-986507) in Combination With Osimertinib Versus Osimertinib Monotherapy or Osimertinib in Combination With Platinum-based Chemotherapy for EGFRmt Non-small Cell Lung Cancer (IZABRIGHT-Lung02) · Phase 3 · Bristol-Myers Squibb
- Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas · Phase 1, Phase 2 · Milton S. Hershey Medical Center
Diabetes & metabolic (17 active studies)
Neurology & pain (14 active studies)
- A Study to Evaluate the Safety and Efficacy of JZP926 Capsule for the Treatment of Juvenile Myoclonic Epilepsy · Phase 2, Phase 3 · Jazz Pharmaceuticals
- Mobile Health Dietary Intervention for Stroke Survivors With Prediabetes or Type 2 Diabetes · University of Hawaii
Cardiovascular (12 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- To Test the Effectiveness and Implementation Approach of a 3-month PILI Pasifika Program Lifestyle Program With Components of Social Determinants of Health Activities in Real-world Settings (Clinical and Non-clinical Settings) Across 3 Years · University of Hawaii
Mental health & behavior (3 active studies)
- Quit-Smoking Study for Native Hawaiians · University of Hawaii
- The Development and Evaluation of a Culturally Grounded ENDS Intervention for Rural Hawaiian Youth · University of Hawaii
Vaccines (2 active studies)
Pediatric (2 active studies)
HIV / STI (1 active study)
Common conditions studied in Honolulu
- Malignant Solid Neoplasm (9 active studies)
- Neuroblastoma (7 active studies)
- Acute Myeloid Leukemia (6 active studies)
- Obesity (6 active studies)
- Breast Cancer (5 active studies)
- Cancer (5 active studies)
Leading research sponsors in Honolulu
- National Cancer Institute (NCI)
- Children's Oncology Group
- University of Hawaii
- NRG Oncology
- SWOG Cancer Research Network
Frequently asked questions
How many paid clinical trials are currently recruiting in Honolulu?
There are approximately 186 recruiting clinical trials in Honolulu, Hawaii listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Honolulu pay participants?
Most recruiting trials in Honolulu compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Honolulu?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Honolulu?
The most common conditions under active study in Honolulu include Malignant Solid Neoplasm (9), Neuroblastoma (7), Acute Myeloid Leukemia (6), Obesity (6), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Honolulu?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Honolulu on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Honolulu?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Honolulu?
Recruiting research sites in Honolulu include Kapiolani Medical Center for Women and Children, Hawaii Cancer Care Inc - Waterfront Plaza, Queen's Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Honolulu right now?
The largest active categories in Honolulu are Cancer & tumors (79), Diabetes & metabolic (17), Neurology & pain (14). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.