Clinical Trials at Texas Children's Hospital

As of September 2026, 99 paid clinical trials are recruiting at Texas Children's Hospital, located at 1 BAYLOR PLZ, BCM 286, N1319, HOUSTON, TX 77030-3411, phone (713) 798-8918 in Houston, Texas. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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100 clinical trials at Texas Children's Hospital

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Distal Radius Interventions for Fracture Treatment

for Fracture Distal Radius

Sites in Houston, Dallas +22 more locations

Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All·Age: 4 - 10

Code: NCT05131685·Recruiting·Listed Nov 2021

Apply to this trial

Rett Syndrome Registry

for Rett Syndrome

Sites in Houston, Dallas +17 more locations

Sponsor: International Rett Syndrome Foundation

Sex: All·Age: 0 - 99

Code: NCT05432349·Recruiting·Listed Jun 2022

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PEEL-224, Vincristine and Temozolomide in Pediatric Solid Tumors

for Refractory Solid Tumors

Sites in Houston +6 more locations

Sponsor: Theodore Laetsch

Sex: All·Age: 1 - 30

Code: NCT06721689·Phase 1, Phase 2·Recruiting·Listed Dec 2024

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Multisite Inventory of Neonatal-Perinatal Interventions (MINI) Minimum Dataset

for Infant, Extremely Premature

Sites in Houston, San Antonio +41 more locations

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 0 - 1

Code: NCT05685745·Recruiting·Listed Jan 2023

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Autologous T-Cells Expressing a Second Generation CAR for Treatment of T-Cell Malignancies Expressing CD5 Antigen

for T-cell Acute Lymphoblastic Lymphoma

2 locations in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: Up to 75

Code: NCT03081910·Phase 1·Recruiting·Listed Mar 2017

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Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

for Liver Cancer

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 1 - 21

Code: NCT04715191·Phase 1·Recruiting·Listed Jan 2021

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C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)

for Diffuse Intrinsic Pontine Glioma

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 12 Months - 25

Code: NCT04099797·Phase 1·Recruiting·Listed Sep 2019

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Childhood Cancer Survivor Study

for Cancer

Sites in Houston, Fort Worth +25 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01120353·Recruiting·Listed May 2010

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Constitutive IL7R (C7R) Modified Banked Allogeneic CD30.CAR EBVSTS for CD30-Positive Lymphomas

for CD30-Positive Diffuse Large B-Cell Lymphoma

2 locations in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 12 - 75

Code: NCT06176690·Phase 1·Recruiting·Listed Dec 2023

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Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

for High Grade Glioma

Sites in Houston +9 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 1 - 21·Accepts healthy volunteers

Code: NCT06333899·EARLY_Phase 1·Recruiting·Listed Mar 2024

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EBV Specific T-Lymphocytes for Treatment of EBV-Positive Lymphoma

for EBV-Related Hodgkin Lymphoma

4 locations in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: All ages

Code: NCT04664179·Phase 1·Recruiting·Listed Dec 2020

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Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

for Hematologic Malignancy

Drug: Venetoclax

Sites in Houston +4 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 0 - 38

Code: NCT06131801·Recruiting·Listed Nov 2023

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Novel Unedited Allo Cell Therapy For High Risk T-Cell Malignancies Using CD7-Specific Car T Cells

for T-cell Acute Lymphoblastic Lymphoma

2 locations in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: Up to 75

Code: NCT07220993·Phase 1·Recruiting·Listed Oct 2025

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VITAS: Atezolizumab in Combination With Chemotherapy for Pediatric Relapsed/Refractory Solid Tumors

for Solid Tumor

Drug: Atezolizumab

Sites in Houston, Dallas +5 more locations

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 6 Months - 30

Code: NCT04796012·Phase 1, Phase 2·Recruiting·Listed Mar 2021

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TETRAVI Multivirus CTL for Treatment of EBV, CMV, Adenovirus, and BK Infections Post Allogeneic SCT.

for Viral Infection

2 locations in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: All ages

Code: NCT04013802·Phase 1·Recruiting·Listed Jul 2019

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CD30 CAR T Cells, Relapsed CD30 Expressing Lymphoma (RELY-30)

for Hodgkin's Lymphoma

2 locations in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 12 - 75

Code: NCT02917083·Phase 1·Recruiting·Listed Sep 2016

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Clinical and Molecular Biomarker Studies in RAI1 (Retinoic Acid-Induced 1) -Related Disorders

for RAI1 Gene 17P11.2 Deletion+Duplication

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 1 Month - 80·Accepts healthy volunteers

Code: NCT06274164·Recruiting·Listed Feb 2024

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HCRN Core Data Project: Characterizing Patient Populations in the Hydrocephalus Clinical Research Network (HCRN)

for Pediatric Hydrocephalus

Sites in Houston +10 more locations

Sponsor: University of Utah

Sex: All·Age: Up to 18

Code: NCT00670735·Recruiting·Listed May 2008

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A Study of Treatment of Inflammation Before Stem Cell Transplant in People With a Primary Immune Regulatory Disorder (PIRD) and/or an Autoinflammatory Condition

for Primary Immune Regulatory Disorder

Sites in Houston +5 more locations

Sponsor: Joseph Oved

Sex: All·Age: All ages

Code: NCT05787574·Phase 2·Recruiting·Listed Mar 2023

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High vs.Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant (SOT) Recipients

for Immunization

Sites in Houston +7 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 3 - 17

Code: NCT05947071·Phase 2·Recruiting·Listed Jul 2023

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Supraglottic Airway for Resuscitation Trial

for Neonatal Resuscitation

Sites in Houston, Dallas +28 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 0 Days+

Code: NCT07150923·Recruiting·Listed Sep 2025

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Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS

for Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS)

Sites in Houston, San Antonio +30 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 1 Day - 17

Code: NCT05267821·Phase 2, Phase 3·Recruiting·Listed Mar 2022

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ACTEMRA® for the Treatment of Pediatric Adamantinomatous Craniopharyngioma

for Adamantinomatous Craniopharyngioma

Sites in Houston +6 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 1 - 39

Code: NCT05233397·Phase 2·Recruiting·Listed Feb 2022

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Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

for High Grade Glioma

Drug: Ribociclib

Sites in Houston +10 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 12 Months - 39

Code: NCT05843253·Phase 2·Recruiting·Listed May 2023

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Outcomes and Health Care Resource Utilization in Pediatric Congenital Heart Disease Patients Undergoing Non-Cardiac Procedures

for Congenital Heart Disease in Children

Sites in Houston +4 more locations

Sponsor: Boston Children's Hospital

Sex: All·Age: Up to 21

Code: NCT04604418·Recruiting·Listed Oct 2020

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Uterine Transplant for Women With Absolute Uterine Factor Infertility (AUFI)

for Mayer Rokitansky Kuster Hauser Syndrome

1 location in Houston

Sponsor: John Goss

Sex: Female·Age: 20 - 65

Code: NCT05263076·Recruiting·Listed Mar 2022

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Fetal Repair of Complex Gastroschisis: A Safety and Feasibility Trial

for Gastroschisis

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: Female·Age: 18+

Code: NCT05704257·Recruiting·Listed Jan 2023

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A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

for High Grade Glioma

Sites in Houston +8 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: Up to 21

Code: NCT04655404·EARLY_Phase 1·Recruiting·Listed Dec 2020

Apply to this trial

Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease

for Aortic Aneurysm

Sites in Houston +13 more locations

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04005976·Recruiting·Listed Jul 2019

Apply to this trial

EVD Drainage Data and Intracranial Pressure (ICP) Measurements

for Hydrocephalus

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 1 - 21

Code: NCT05546996·Recruiting·Listed Sep 2022

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Cytotoxic T-Lymphocytes for EBV-positive Lymphoma, GRALE

for Hodgkin's Disease

3 locations in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: All ages

Code: NCT01555892·Phase 1·Recruiting·Listed Mar 2012

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Modernizing Perinatal Syphilis Testing

for Syphilis

Sites in Houston +8 more locations

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: Up to 45

Code: NCT06082453·Recruiting·Listed Oct 2023

Apply to this trial

Neurophysiologic Biomarkers in Rett Syndrome

for Rett Syndrome

Sites in Houston +5 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: Female·Age: 1 - 18·Accepts healthy volunteers

Code: NCT05932589·Recruiting·Listed Jul 2023

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HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma

for Sarcoma

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 1 - 25

Code: NCT04995003·Phase 1·Recruiting·Listed Aug 2021

Apply to this trial

Targeted Therapy to Increase RAI Uptake in Metastatic DTC

for Papillary Thyroid Cancer

Sites in Houston +7 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 0+

Code: NCT05024929·Recruiting·Listed Aug 2021

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The ExTINGUISH Trial of Inebilizumab in NMDAR Encephalitis

for Autoimmune Encephalitis

Drug: Inebilizumab

Sites in Houston, Dallas +33 more locations

Sponsor: University of Utah

Sex: All·Age: 12+

Code: NCT04372615·Phase 2·Recruiting·Listed May 2020

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STXBP1 and SYNGAP1 Related Disorders Natural History Study

for Genetic Disease

Sites in Houston +4 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT06555965·Recruiting·Listed Aug 2024

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Activated T-Cells Expressing 2nd or 3rd Generation CD19-Specific CAR, Advanced B-Cell NHL, ALL, and CLL (SAGAN)

for Non-Hodgkin Lymphoma

2 locations in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: Up to 75

Code: NCT01853631·Phase 1·Recruiting·Listed May 2013

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HCRN Endoscopic Versus Shunt Treatment of Hydrocephalus in Infants

for Hydrocephalus

Sites in Houston +14 more locations

Sponsor: University of Utah

Sex: All·Age: 1 Day - 104 Weeks

Code: NCT04177914·Phase 3·Recruiting·Listed Nov 2019

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Vinblastine/Prednisone Versus Single Therapy With Cytarabine for Langerhans Cell Histiocytosis (LCH)

for Langerhans Cell Histiocytosis

Sites in Houston, Austin +8 more locations

Sponsor: Baylor College of Medicine

Sex: All·Age: Up to 21

Code: NCT02670707·Phase 3·Recruiting·Listed Feb 2016

Apply to this trial