Non-invasive Prediction of EArly Cardiac rEjection
for Heart Transplant
Sites in Houston +21 more locations
Sponsor: Vanderbilt University Medical Center
Sex: All·Age: 6 - 25
Code: NCT07770659·Recruiting·Listed Aug 18, 2026
Clinical Trials at Texas Children's Hospital
As of September 2026, 99 paid clinical trials are recruiting at Texas Children's Hospital, located at 1 BAYLOR PLZ, BCM 286, N1319, HOUSTON, TX 77030-3411, phone (713) 798-8918 in Houston, Texas. Active studies at this site cover conditions such as Breast Cancer, Acute Myeloid Leukemia and Advanced Solid Tumor. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Houston
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
100 clinical trials at Texas Children's Hospital
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A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis
for Colitis, Ulcerative
Sites in Houston, Fort Worth +16 more locations
Sponsor: Bristol-Myers Squibb
Sex: All·Age: 2 - 17
Code: NCT05076175·Phase 2, Phase 3·Recruiting·Listed Oct 2021
Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)
for Spinal Muscular Atrophy (SMA)
Sites in Houston, San Antonio +40 more locations
Sponsor: Novartis Pharmaceuticals
Sex: All·Age: All ages
Code: NCT04174157·Recruiting·Listed Nov 2019
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2
for Single Ventricle Heart Disease
Sites in Houston, Dallas +35 more locations
Sponsor: Mezzion Pharma Co. Ltd
Sex: All·Age: 12 - 18
Code: NCT05918211·Phase 3·Recruiting·Listed Jun 2023
EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease
for COVID-19
Sites in Houston, Shavano Park +22 more locations
Sponsor: Pfizer
Sex: All·Age: 0 - 17
Code: NCT05261139·Phase 3·Recruiting·Listed Mar 2022
A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy
for Spinal Muscular Atrophy (SMA)
Sites in Houston, Flower Mound +13 more locations
Sponsor: argenx
Sex: All·Age: 5 - 17
Code: NCT07287982·Phase 2·Recruiting·Listed Dec 2025
Phase 2b Study of RPT904 as Monotherapy in Participants With IgE-Mediated Food Allergy
for Ig-E Mediated Food Allergy
Drug: RPT904
Sites in Houston, Austin +20 more locations
Sponsor: RAPT Therapeutics, Inc., a member of the GSK plc group of companies
Sex: All·Age: 12 - 55
Code: NCT07220811·Phase 2·Recruiting·Listed Oct 2025
A Study of Pitolisant in Patients With Prader-Willi Syndrome
for Prader-Willi Syndrome
Sites in Houston, San Antonio +17 more locations
Sponsor: Harmony Biosciences Management, Inc.
Sex: All·Age: 6+
Code: NCT06366464·Phase 3·Recruiting·Listed Apr 2024
A Phase 2 Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation (The ReInspire Study)
for PIK3CA-Related Overgrowth Spectrum (PROS)
Sites in Houston +21 more locations
Sponsor: Relay Therapeutics, Inc.
Sex: All·Age: 2+
Code: NCT06789913·Phase 2·Recruiting·Listed Jan 2025
Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy
for Spinal Muscular Atrophy
Sites in Houston +14 more locations
Sponsor: Alcyone Therapeutics, Inc
Sex: All·Age: 3+
Code: NCT05866419·Recruiting·Listed May 2023
REVEAL: A Phase 3 Study of Obudanersen (ION582) in Angelman Syndrome
for Angelman Syndrome
Sites in Houston +17 more locations
Sponsor: Ionis Pharmaceuticals, Inc.
Sex: All·Age: 2 - 50
Code: NCT06914609·Phase 3·Recruiting·Listed Apr 2025
Study of Olutasidenib and Temozolomide in HGG
for High Grade Glioma
Sites in Houston +10 more locations
Sponsor: Rigel Pharmaceuticals
Sex: All·Age: 12 - 39
Code: NCT06161974·Phase 2·Recruiting·Listed Dec 2023
Open-label Study of ELA026 in Participants With Secondary Hemophagocytic Lymphohistiocytosis (sHLH)
for Secondary Hemophagocytic Lymphohistiocytosis (sHLH)
Sites in Houston +15 more locations
Sponsor: Electra Therapeutics Inc.
Sex: All·Age: 6+
Code: NCT05416307·Phase 2, Phase 3·Recruiting·Listed Jun 2022
Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases
for Focal Segmental Glomerulosclerosis
Drug: Sparsentan
Sites in Houston +16 more locations
Sponsor: Travere Therapeutics, Inc.
Sex: All·Age: 1 - 17
Code: NCT05003986·Phase 2·Recruiting·Listed Aug 2021
A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)
for Crohn's Disease (CD)
Sites in Houston +14 more locations
Sponsor: Takeda
Sex: All·Age: 2 - 17
Code: NCT04779320·Phase 3·Recruiting·Listed Mar 2021
52 Week Study + 24-Month Long-Term Extension of Safety, PK, & Efficacy of XYOSTED® for Testosterone Replacement in Male Adolescents With Hypogonadism
for Hypogonadism, Male
Sites in Houston, El Paso +18 more locations
Sponsor: Halozyme Therapeutics
Sex: Male·Age: 12 - 17
Code: NCT06689085·Phase 3·Recruiting·Listed Nov 2024
Open-Label Study of mRNA-3927 in Participants With Propionic Acidemia
for Propionic Acidemia
Sites in Houston +10 more locations
Sponsor: ModernaTX, Inc.
Sex: All·Age: All ages
Code: NCT04159103·Phase 1, Phase 2·Recruiting·Listed Nov 2019
A Study to Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors
for Low-grade Glioma
Sites in Houston +11 more locations
Sponsor: Day One Biopharmaceuticals, Inc.
Sex: All·Age: 6 Months - 25
Code: NCT04775485·Phase 2·Recruiting·Listed Mar 2021
QUELIMMUNE (SCD-PED) PediAtric SurVeillance REgistry
for Acute Kidney Injury
Sites in Houston, Dallas +13 more locations
Sponsor: SeaStar Medical
Sex: All·Age: Up to 22
Code: NCT06517810·Recruiting·Listed Jul 2024
First-in-human Study of a New Treatment (4A10) for Patients With Relapsed or Hard-to-treat Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma, Focused on Safety and How the Drug Behaves in the Body and Early Signs of Effect.
for Lymphoblastic Lymphoma
Sites in Houston, Fort Worth +5 more locations
Sponsor: Allterum Therapeutics, Inc
Sex: All·Age: 18+
Code: NCT07586618·Phase 1·Recruiting·Listed May 2026
Danon Disease Natural History Study
for Danon Disease
Sites in Houston, Dallas +7 more locations
Sponsor: Rocket Pharmaceuticals Inc.
Sex: All·Age: 8+
Code: NCT06214507·Recruiting·Listed Jan 2024
AERA Pediatrics Registry
for Dysfunction of Eustachian Tube
Sites in Houston, Fort Worth +7 more locations
Sponsor: Integra LifeSciences Corporation
Sex: All·Age: Up to 18
Code: NCT07071298·Recruiting·Listed Jul 2025
A Feasibility Safety Study of Benign Centrally-Located Intracranial Tumors in Pediatric and Young Adult Subjects
for Benign Centrally-Located Intracranial Tumors
Sites in Houston +2 more locations
Sponsor: InSightec
Sex: All·Age: 5 - 22
Code: NCT03028246·Recruiting·Listed Jan 2017
A Study to Assess the Long-term Safety and Clinical Activity of mRNA-3927 in Participants Previously Enrolled in the mRNA-3927-P101 Study
for Propionic Acidemia
Sites in Houston +6 more locations
Sponsor: ModernaTX, Inc.
Sex: All·Age: 1+
Code: NCT05130437·Phase 1, Phase 2·Recruiting·Listed Nov 2021
A Study of Participants with Β-Thalassemia Treated with Betibeglogene Autotemcel
for Beta-Thalassemia
Sites in Houston +5 more locations
Sponsor: Genetix Biotherapeutics Inc.
Sex: All·Age: All ages
Code: NCT06271512·Recruiting·Listed Feb 2024
Bowel Continence Across the Lifespan in People With Spina Bifida
for Spina Bifida
Sites in Houston, Dallas +22 more locations
Sponsor: David Chu
Sex: All·Age: 5+
Code: NCT07390318·Recruiting·Listed Feb 2026
Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)
for Acute Myeloid Leukemia
Drug: Venetoclax
Sites in Houston, Dallas +43 more locations
Sponsor: PedAL BCU, LLC
Sex: All·Age: 29 Days - 21
Code: NCT05183035·Phase 3·Recruiting·Listed Jan 2022
Electrophysiologic Sleep Phenotyping and Sleep-Dependent Neuro-maturation in Clinical and Healthy Pediatric Populations
for Healthy Children
Sites in Houston +4 more locations
Sponsor: National Institute of Mental Health (NIMH)
Sex: All·Age: 6 Months - 8·Accepts healthy volunteers
Code: NCT04639830·Recruiting·Listed Nov 2020
Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study
for Chronic Pancreatitis
Sites in Houston, San Antonio +20 more locations
Sponsor: M.D. Anderson Cancer Center
Sex: All·Age: Up to 17
Code: NCT06651580·Recruiting·Listed Oct 2024
Targeted Pediatric High-Grade Glioma Therapy
for High Grade Glioma
Sites in Houston +11 more locations
Sponsor: Nationwide Children's Hospital
Sex: All·Age: 12 Months - 39
Code: NCT05839379·Recruiting·Listed May 2023
ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas
for Diffuse Intrinsic Pontine Gliomas (DIPG)
Sites in Houston +11 more locations
Sponsor: Nationwide Children's Hospital
Sex: All·Age: 12 Months - 39
Code: NCT06838676·Phase 2·Recruiting·Listed Feb 2025
Optimal Pediatric Heart Transplant Immunosuppression With MicroRNAs
for Cardiac Failure
Sites in Houston +6 more locations
Sponsor: Northwestern University
Sex: All·Age: Up to 18
Code: NCT06532890·Recruiting·Listed Aug 2024
PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma
for High Grade Glioma
Sites in Houston +12 more locations
Sponsor: Nationwide Children's Hospital
Sex: All·Age: 3 - 39
Code: NCT05096481·Phase 2·Recruiting·Listed Oct 2021
Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma
for Medulloblastoma
Sites in Houston, Dallas +8 more locations
Sponsor: St. Jude Children's Research Hospital
Sex: All·Age: Up to 59 Months
Code: NCT05535166·Phase 2·Recruiting·Listed Sep 2022
Cord Clamping Among Neonates With Congenital Heart Disease
for Congenital Heart Disease (CHD)
Sites in Houston, San Antonio +16 more locations
Sponsor: Carl Backes, MD
Sex: All·Age: 37 Weeks - 42 Weeks
Code: NCT06153459·Recruiting·Listed Dec 2023
Humidity in Incubators for Tiny Infants
for Extremely Premature Infant
Sites in Houston, San Antonio +7 more locations
Sponsor: The University of Texas Health Science Center, Houston
Sex: All·Age: 0 Days - 1 Day
Code: NCT06399861·Recruiting·Listed May 2024
Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS)
for Obstructive Sleep Apnea
Sites in Houston, Dallas +4 more locations
Sponsor: Oregon Health and Science University
Sex: All·Age: 2 - 17
Code: NCT05508971·Recruiting·Listed Aug 2022
Trivalent CAR-T Cell in Acute B-Lineage Leukemia (TRICAR-ALL)
for Leukemia, B-Cell
1 location in Houston
Sponsor: Baylor College of Medicine
Sex: All·Age: 12 Months - 25
Code: NCT05010564·Phase 1·Recruiting·Listed Aug 2021
Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors
for Malignant Solid Tumors
Sites in Houston +2 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 4 Weeks+·Accepts healthy volunteers
Code: NCT03739827·Recruiting·Listed Nov 2018
Neurodevelopmental Outcomes in Children: Strengthening the Caregiver-Child Story
for Food Insecurity
1 location in Houston
Sponsor: Baylor College of Medicine
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT05809115·Recruiting·Listed Apr 2023
Study of the ITK Inhibitor Soquelitinib to Reduce Lymphoproliferation and Improve Cytopenias in Autoimmune Lymphoproliferative Syndrome (ALPS)-FAS Patients
for Autoimmune Lymphoproliferative Syndrome
Drug: Soquelitinib
Sites in Houston +2 more locations
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Sex: All·Age: 16 - 120
Code: NCT06730126·Phase 2·Recruiting·Listed Dec 2024
Common conditions studied in Houston
- Breast Cancer (76 active studies)
- Acute Myeloid Leukemia (54 active studies)
- Advanced Solid Tumor (52 active studies)
- Colorectal Cancer (47 active studies)
- Ovarian Cancer (47 active studies)
- Prostate Cancer (45 active studies)
Leading research sponsors in Houston
- M.D. Anderson Cancer Center
- The University of Texas Health Science Center, Houston
- Baylor College of Medicine
- AstraZeneca
- The Methodist Hospital Research Institute
Frequently asked questions
How many paid clinical trials are currently recruiting in Houston?
There are approximately 3,049 recruiting clinical trials in Houston, Texas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Houston pay participants?
Most recruiting trials in Houston compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Houston?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Houston?
The most common conditions under active study in Houston include Breast Cancer (76), Acute Myeloid Leukemia (54), Advanced Solid Tumor (52), Colorectal Cancer (47), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Houston?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Houston on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Houston?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Houston?
Recruiting research sites in Houston include MD Anderson Cancer Center, M D Anderson Cancer Center, Baylor College of Medicine, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Houston right now?
The largest active categories in Houston are Cancer & tumors (1,179), Neurology & pain (138), Cardiovascular (105). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of Texas Children's Hospital?
Texas Children's Hospital is located at 1 BAYLOR PLZ, BCM 286, N1319, HOUSTON, TX 77030-3411. Use the Google Maps link in the intro above to get directions.
How do I contact Texas Children's Hospital?
You can reach Texas Children's Hospital by phone at (713) 798-8918. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.
Browse more clinical trials
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