Paid Clinical Trials in Iowa

Iowa has 757 paid clinical trials enrolling now across cities including Iowa City, Des Moines and Waukee. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

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700 clinical trials

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Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy.

for Kidney Diseases

Sites in Iowa City +8 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT06858319·Phase 3·Recruiting·Listed Mar 2025

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A Study to Learn About the Safety and Effects of the Study Drug PRX-102 in Children and Adolescents With Fabry Disease

for Fabry Disease

Sites in Iowa City +5 more locations

Sponsor: Chiesi Farmaceutici S.p.A.

Sex: All·Age: 2 - 17

Code: NCT06328608·Phase 2, Phase 3·Recruiting·Listed Mar 2024

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NV PSR INSPIRE-A Pipeline™ Vantage Post Approval Study

for Intracranial Aneurysm

Sites in Iowa City +7 more locations

Sponsor: Medtronic Neurovascular Clinical Affairs

Sex: All·Age: 22+

Code: NCT06604884·Recruiting·Listed Sep 2024

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Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGN

for C3 Glomerulopathy

Drug: Iptacopan

Sites in Iowa City +4 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 100

Code: NCT03955445·Phase 3·Recruiting·Listed May 2019

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TulmiSTAR-02: A Phase I/II Open-label Study of Tulmimetostat in Combination With Darolutamide vs. Darolutamide, and Tulmimetostat With Abiraterone in Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

for Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)

Drug: Tulmimetostat

Sites in Iowa City +7 more locations

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18+

Code: NCT07190300·Phase 1, Phase 2·Recruiting·Listed Sep 2025

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Closed Loop Oxygen Control in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Nasal High Flow in the Hospital

for COPD

Sites in Des Moines +3 more locations

Sponsor: Fisher and Paykel Healthcare

Sex: All·Age: 22+

Code: NCT07222410·Recruiting·Listed Oct 2025

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Long-term Follow-up of a Cochlear Implant With Dexamethasone Eluting Electrode Array

for Sensorineural Hearing Loss

Sites in Iowa City +2 more locations

Sponsor: Cochlear

Sex: All·Age: 18+

Code: NCT06936449·Recruiting·Listed Apr 2025

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Study of RYZ401 in Subjects With Solid Tumors Expressing SSTRs.

for GEP-NET

Sites in Iowa City +6 more locations

Sponsor: RayzeBio, Inc.

Sex: All·Age: 18+

Code: NCT07165132·Phase 1·Recruiting·Listed Sep 2025

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Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

for Cervical Cancer

Sites in Iowa City +6 more locations

Sponsor: Orano Med Theranostics, SAS

Sex: All·Age: 18+

Code: NCT05283330·Phase 1·Recruiting·Listed Mar 2022

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A First-in-human, Dose Escalation and Dose Expansion Study of SAR445877 in Adult Participants With Advanced Solid Tumors

for Solid Tumor

Sites in Iowa City +8 more locations

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT05584670·Phase 1, Phase 2·Recruiting·Listed Oct 2022

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SPI-1005 in Adults Receiving Cochlear Implant

for Hearing Loss

Sites in Iowa City +5 more locations

Sponsor: Sound Pharmaceuticals, Incorporated

Sex: All·Age: 18+

Code: NCT06340633·Phase 2·Recruiting·Listed Apr 2024

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Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION)

for Leber Congenital Amaurosis 10

Sites in Iowa City +4 more locations

Sponsor: Laboratoires Thea

Sex: All·Age: 6+

Code: NCT06891443·Phase 3·Recruiting·Listed Mar 2025

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BGB-21447 (Bcl-2 Inhibitor) Combinations for Adults With Hormone-Receptor Positive (HR+)/Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Metastatic Breast Cancer

for Hormone-receptor-positive Breast Cancer

Sites in Iowa City +2 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06756932·Phase 1·Recruiting·Listed Jan 2025

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A Study to Evaluate the Efficacy and Safety of Sutetinib Maleate Capsule in Locally Advanced or Metastatic NSCLC

for Non-small Cell Lung Cancer

Sites in Des Moines +5 more locations

Sponsor: Teligene US

Sex: All·Age: 18+

Code: NCT06010329·Phase 2·Recruiting·Listed Aug 2023

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Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-101 in Participants With Myotonic Dystrophy Type 1

for Myotonic Dystrophy Type 1 (DM1)

Sites in Iowa City +7 more locations

Sponsor: Dyne Therapeutics

Sex: All·Age: 18 - 65

Code: NCT05481879·Phase 1, Phase 2·Recruiting·Listed Aug 2022

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Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns

for Burns

Sites in Iowa City +3 more locations

Sponsor: Skingenix, Inc.

Sex: All·Age: 18+

Code: NCT01297400·Phase 2·Recruiting·Listed Feb 2011

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Study of ATX-01 in Participants With DM1

for Myotonic Dystrophy 1

Sites in Iowa City +4 more locations

Sponsor: ARTHEx Biotech S.L.

Sex: All·Age: 18 - 64

Code: NCT06300307·Phase 1, Phase 2·Recruiting·Listed Mar 2024

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Gene Therapy Trial for Otoferlin Gene-mediated Hearing Loss

for Sensorineural Hearing Loss, Bilateral

Sites in Iowa City +5 more locations

Sponsor: Akouos, Inc.

Sex: All·Age: All ages

Code: NCT05821959·Phase 1, Phase 2·Recruiting·Listed Apr 2023

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Otoferlin Gene-mediated Hearing Loss Natural History Study

for Sensorineural Hearing Loss, Bilateral

Sites in Iowa City +3 more locations

Sponsor: Akouos, Inc.

Sex: All·Age: Up to 44

Code: NCT05572073·Recruiting·Listed Oct 2022

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A Study to Assess the Safety and Efficacy of LB-P8 in Patients With PSC

for Primary Sclerosing Cholangitis (PSC)

Sites in Iowa City +6 more locations

Sponsor: LISCure Biosciences

Sex: All·Age: 18 - 75

Code: NCT06699121·Phase 2·Recruiting·Listed Nov 2024

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Efanesoctocog Alfa Prophylaxis in Patients With Hemophilia A With Synovial Hypertrophy

for Factor VIII Deficiency

Sites in Iowa City +3 more locations

Sponsor: Sanofi

Sex: All·Age: 12+

Code: NCT06941870·Phase 4·Recruiting·Listed Apr 2025

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Single-Sided Deafness and Asymmetric Hearing Loss

for Hearing Loss, Unilateral

Sites in Iowa City +2 more locations

Sponsor: Med-El Corporation

Sex: All·Age: 5+

Code: NCT04506853·Recruiting·Listed Aug 2020

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Investigation to Evaluate the Safety and Effectiveness of Cochlear Implantation in Children and Adults With Unilateral Hearing Loss/Single-sided Deafness

for Hearing Loss, Unilateral

Sites in Iowa City +5 more locations

Sponsor: Cochlear

Sex: All·Age: 5+

Code: NCT05318417·Recruiting·Listed Apr 2022

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Outcomes Following Combined Adductoplasty™ and Lapiplasty® (MTA3D)

for Metatarsus Adductus

Sites in Ankeny +8 more locations

Sponsor: Treace Medical Concepts, Inc.

Sex: All·Age: 14 - 65·Accepts healthy volunteers

Code: NCT05587569·Recruiting·Listed Oct 2022

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A Multi-Country Observational Study of Safety and Effectiveness of Elfabrio® in Fabry Patients

for Fabry Disease

Sites in Iowa City +5 more locations

Sponsor: Chiesi Farmaceutici S.p.A.

Sex: All·Age: 18+

Code: NCT06663358·Recruiting·Listed Oct 2024

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PAVE (Parallactic Visual-Field Enhancement) System for Treatment of Chronic Visual Field Loss Due to Stroke, Traumatic Brain Injury, or Brain Surgery

for Homonymous Hemianopsia

Sites in Cedar Rapids +1 more location

Sponsor: NeuroAEye LLC

Sex: All·Age: 21 - 80

Code: NCT07185971·Recruiting·Listed Sep 2025

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Post-Market Clinical Investigation of the IotaSOFT Insertion System

for Hearing Loss, Cochlear

Sites in Iowa City +2 more locations

Sponsor: iotaMotion, Inc.

Sex: All·Age: 12+

Code: NCT06664697·Recruiting·Listed Oct 2024

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Encore PFO Closure Device - The PerFOrm Trial

for Patent Foramen Ovale

Sites in West Des Moines +7 more locations

Sponsor: Encore Medical Inc.

Sex: All·Age: 18 - 60

Code: NCT05537753·Recruiting·Listed Sep 2022

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Evaluation of the Automated Integration of a Robotics and ECochG System for Use With Cochlear Implant Surgery

for Hearing Loss, Sensorineural

1 location in Iowa City

Sponsor: iotaMotion, Inc.

Sex: All·Age: 12+

Code: NCT06664710·Recruiting·Listed Oct 2024

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Utilizing Novel Blood RNA Biomarkers as a Diagnostic Tool in the Identification of Long COVID-19

for Long COVID

Sites in Iowa City +2 more locations

Sponsor: MaxWell Clinic, PLC

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06311435·Recruiting·Listed Mar 2024

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Test-retest Evaluation of [18F]F-AraG PET

for Non-small Cell Lung Cancer

1 location in Iowa City

Sponsor: CellSight Technologies, Inc.

Sex: All·Age: 18+

Code: NCT06084806·Phase 2·Recruiting·Listed Oct 2023

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Imaging Advanced NSCLC Patients Undergoing PD-1/PD-L1 Directed Therapy Using [18F]-FARAG

for Advanced Non Small Cell Lung Cancer

1 location in Iowa City

Sponsor: CellSight Technologies, Inc.

Sex: All·Age: 18+

Code: NCT06107374·Phase 2·Recruiting·Listed Oct 2023

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Tailor VHA HH Bundle for Acute Mental Health Care

for Hand Hygiene Compliance

Sites in Iowa City +3 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 90

Code: NCT07607145·Recruiting·Listed May 2026

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Duchenne Electronic Health Record Study

for Duchenne Muscular Dystrophy (DMD)

Sites in Iowa City +9 more locations

Sponsor: The Duchenne Registry

Sex: All·Age: All ages

Code: NCT07609394·Recruiting·Listed May 2026

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CHAMP Lung Cancer Screening Program

for Lung Cancer

Sites in Iowa City & Waterloo

Sponsor: Jill Kolesar

Sex: All·Age: 50 - 77

Code: NCT07572773·Recruiting·Listed May 2026

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Sirolimus Pre-conditioning on T Cell Activity and T-cell Engaging Bispecific Antibody Efficacy in Multiple Myeloma

for Multiple Myeloma

1 location in Iowa City

Sponsor: Christopher Strouse

Sex: All·Age: 18+

Code: NCT07581704·Phase 1·Recruiting·Listed May 2026

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A Study of Methylprednisolone in People Having Liver Surgery

for Hepatectomy

Sites in Iowa City +18 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT07507643·Phase 3·Recruiting·Listed Apr 2026

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Sitagliptin in Recurrent/Progressive Grade 4 Glioma

for Glioma

1 location in Iowa City

Sponsor: Kailin Yang, MD, PhD

Sex: All·Age: 18+

Code: NCT07541781·Phase 1·Recruiting·Listed Apr 2026

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Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial

for Anatomic Stage II Breast Cancer AJCC v8

Drug: Ribociclib

Sites in Des Moines, Waukee +171 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07391774·Phase 3·Recruiting·Listed Feb 2026

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Quality of End-of-Life Care for Children With Cancer

for Childhood Hematopoietic and Lymphatic System Neoplasm

Sites in Des Moines +27 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07412002·Recruiting·Listed Feb 2026

Apply to this trial