Paid Clinical Trials in Illinois

Illinois has 2,968 paid clinical trials enrolling now across cities including Chicago, Peoria and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Illinois include Northwestern Medicine, University of Chicago Medicine and Rush, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 18, 2026.

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2,968 clinical trials

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A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia

for Dystonia

37 locations incl. Birmingham

Sponsor: Vima Therapeutics

Sex: All·Age: 18 - 65

Code: NCT07304089·Phase 2·Recruiting

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Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants Undergoing Open Abdominal Ventral Hernia Repair

for Ventral Hernia

11 locations incl. Riverside

Sponsor: AbbVie

Sex: All·Age: 18 - 80

Code: NCT07226791·Phase 2·Recruiting

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A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder

for Bipolar I Disorder

Drug: Icalcaprant

31 locations incl. Huntsville

Sponsor: AbbVie

Sex: All·Age: 18 - 65

Code: NCT06696755·Phase 2·Recruiting

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Using Implementation Science to Adapt a Targeted Transportation Intervention for Patients With Diabetic Retinopathy (PRONTO-EYE)

for Diabetic Retinopathy (DR)

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18+

Code: NCT07296952·Recruiting

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Cytokine Response to Abdominal Wall Reconstruction

for Incisional Ventral Hernia

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07422584·Recruiting

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Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

for Gastric Cancer

Drug: Sonesitatug vedotin

77 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07431281·Phase 3·Recruiting

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Pharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa

for Hidradenitis Suppurativa (HS)

Drug: Povorcitinib

25 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 12 - 17

Code: NCT07213973·Phase 2·Recruiting

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GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes

for Type 1 Diabetes Mellitus

34 locations incl. Little Rock

Sponsor: Medtronic MiniMed, Inc.

Sex: All·Age: 7 - 85

Code: NCT07228117·Recruiting

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Evaluation of the Efficacy and Safety of Magnetic Resonance Angiography (MRA) Using Gadopiclenol Compared to Gadoterate Meglumine in the Assessment of Steno-occlusive Disease in Adult Patients With Suspected Vascular Disease

for Steno-occlusive Disease

6 locations incl. Los Angeles

Sponsor: Guerbet

Sex: All·Age: 18+

Code: NCT07348640·Phase 3·Not Yet Recruiting

FFP In Traumatic BRAin INjury (FIT-BRAIN) Trial

for Moderate to Severe Traumatic Brain Injury

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18 - 65

Code: NCT06062888·Phase 2, Phase 3·Recruiting

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Probiotic Supplementation in Optimizing Iron and Hematological Status Among Pregnant Females

for Iron Deficiency (ID)

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT07076849·Phase 2·Recruiting

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Estimating Insulin Sensitivity in Pregnancies With Type 1 Diabetes

for Pregnancy

2 locations incl. Chicago

Sponsor: University of Virginia

Sex: Female·Age: 18+

Code: NCT07351318·Enrolling By Invitation

Feasibility and Acceptibility of a Multi-site Trial of Time Restircted Eating During Chemotheraply for Breast Cancer.

for Breast Cancer Early Stage Breast Cancer (Stage 1-3)

2 locations incl. Chicago

Sponsor: University of Illinois at Chicago

Sex: Female·Age: 25 - 99

Code: NCT07387445·Recruiting

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BRIDGE - Blocking Receptor of IL-1β for Donor Graft Edema Reduction

for Lung Transplant Recipient

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07410312·EARLY_Phase 1·Not Yet Recruiting

Evaluating Whether Intact Fish Skin Graft Can Decrease the Need for Autograft in the Treatment of Deep Partial-Thickness Burns

for Partial-thickness Burn Wounds

1 location in Maywood

Sponsor: Kerecis Ltd.

Sex: All·Age: 18+

Code: NCT07326657·Phase 4·Enrolling By Invitation

Impact of Barostimulation on Hemodynamics in Adults With Heart Failure

for HFrEF - Heart Failure With Reduced Ejection Fraction

7 locations incl. San Francisco

Sponsor: Columbia University

Sex: All·Age: 18+

Code: NCT07335510·Not Yet Recruiting

Moving Foward With Myeloma (MFM)

for Multiple Myeloma (MM)

2 locations incl. Maywood

Sponsor: Medical College of Wisconsin

Sex: All·Age: 18+

Code: NCT07236502·Not Yet Recruiting

Increasing Germline Genetic Testing for Patients With Cancer

for Hereditary Pancreatic Cancer

10 locations incl. Los Angeles

Sponsor: Josh Peterson

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT07307664·Recruiting

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Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder

for Opioid Use Disorder

Drug: Tirzepatide

9 locations incl. Jacksonville

Sponsor: T. John Winhusen, PhD

Sex: All·Age: 18+

Code: NCT06651177·Phase 2·Recruiting

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A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (EMERGENT TEEN)

for Schizophrenia

Drug: KarXT

18 locations incl. Anaheim

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 13 - 17

Code: NCT07288567·Phase 3·Recruiting

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Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)

for Hepatitis

Drug: Larsucosterol

48 locations incl. Birmingham

Sponsor: Bausch Health Americas, Inc.

Sex: All·Age: 18+

Code: NCT07428538·Phase 3·Recruiting

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Effect of Early Parent Education on Children's Sleep

for Sleep

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT07515534·Recruiting

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Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

for Advanced Endometrial Carcinoma

Drug: Bevacizumab

218 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT07198074·Phase 3·Recruiting

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Study to Assess the Real-World Effectiveness of Ubrogepant in Adult Participants When Treating During the Prodrome Phase of Migraine Attacks

for Migraine

Drug: Ubrogepant

3 locations incl. Aliso Viejo

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07310290·Recruiting

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Flow Detection in Open and Closed Shunt Valve Periods

for Hydrocephalus

1 location in Peoria

Sponsor: Rhaeos, Inc.

Sex: All·Age: All ages

Code: NCT07478926·Recruiting

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Integrating MOUD in Nonmedical Community Settings (Better Together)

for Opioid Use Disorder

4 locations incl. Washington D.C.

Sponsor: Howard University

Sex: All·Age: 16+

Code: NCT06416020·Not Yet Recruiting

Evaluation of the Rigicon Infla10® Inflatable Penile Prosthesis (IPP) for Erectile Dysfunction

for Erectile Dysfunction (ED)

7 locations incl. Coral Gables

Sponsor: Rigicon, Inc.

Sex: Male·Age: 22+

Code: NCT07273773·Recruiting

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Supporting Caregivers Following Mental Health Emergency Department Visits

for Caregiver Participation

1 location in Chicago

Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All·Age: 10 - 17

Code: NCT07411300·Recruiting

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Study of ABBV-142 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Idiopathic Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis

3 locations incl. Dothan

Sponsor: AbbVie

Sex: All·Age: 40+

Code: NCT07230288·Phase 2·Recruiting

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Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE.

for Bipolar I Disorder

26 locations incl. Bentonville

Sponsor: LB Pharmaceuticals Inc.

Sex: All·Age: 18 - 65

Code: NCT07494305·Phase 2·Recruiting

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ECHO Diabetes FQHC

for Diabetes

2 locations incl. Miami

Sponsor: University of Florida

Sex: All·Age: 18+

Code: NCT07417865·Recruiting

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EVR and EPO for Liver Transplant Tolerance

for Liver Transplant

3 locations incl. San Francisco

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+

Code: NCT06832189·Phase 1·Recruiting

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A Multicenter Prospective Observational Cohort Study Evaluating the Impact of Cancer-Directed Treatment and Medication Use, Including Cannabis Use, in Multiple Myeloma Patients

for Multiple Myeloma

11 locations incl. Goodyear

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07225738·Recruiting

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A Study to Evaluate the Effect of KarXT on Urological Safety

for Schizophrenia

Drug: KarXT

13 locations incl. Little Rock

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18 - 65

Code: NCT07221877·Phase 4·Recruiting

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A Study of JNJ-95597528 in Participants With Moderate to Severe Atopic Dermatitis

for Dermatitis, Atopic

12 locations incl. Fountain Valley

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07230860·Phase 2·Recruiting

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Prospective HemorrhoIdaL EmboliSation (PILES) Registry

for Hemorrhoid

1 location in Libertyville

Sponsor: Joint & Vascular Institute

Sex: All·Age: 18+

Code: NCT07635784·Recruiting

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Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD Mutations

for Non-small Cell Lung Cancer

29 locations incl. Fresno

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07195695·Phase 3·Recruiting

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Lifestyle Interventions to Prevent Diabetes in U.S. Home Visiting Programs

for Diabetes Mellitus

3 locations incl. San Luis Obispo

Sponsor: California Polytechnic State University-San Luis Obispo

Sex: Female·Age: 18+

Code: NCT06988306·Recruiting

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Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network, STOP-VTE Study

for Malignant Digestive System Neoplasm

58 locations incl. Fort Smith

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07215624·Recruiting

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A Study to Investigate Efficacy, Safety and Tolerability of Barzolvolimab Versus Placebo in Adults With Cold Induced Urticaria and Symptomatic Dermographism Inadequately Controlled by H1-antihistamines (EMBARQ - ColdU and SD)

for Chronic Inducible Urticaria

26 locations incl. Birmingham

Sponsor: Celldex Therapeutics

Sex: All·Age: 18+

Code: NCT07266402·Phase 3·Recruiting

Apply to this trial