Paid Clinical Trials in Illinois

Illinois has 2,846 paid clinical trials enrolling now across cities including Chicago, Peoria and Evanston. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Illinois include Northwestern Medicine, University of Chicago Medicine and Rush, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

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2,519 clinical trials

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A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

for Metastatic Uveal Melanoma

Drug: Nivolumab

Sites in Chicago +28 more locations

Sponsor: Replimune, Inc.

Sex: All·Age: All ages

Code: NCT06581406·Phase 2, Phase 3·Recruiting·Listed Sep 2024

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GEMINI-NSCLC: NSCLC Biomarker Study

for Non-Small Cell Lung Cancer

Sites in Evanston, Decatur +54 more locations

Sponsor: Tempus AI

Sex: All·Age: 18+

Code: NCT05236114·Recruiting·Listed Feb 2022

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A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer

for Gastroesophageal-junction Cancer

Sites in Chicago +28 more locations

Sponsor: Shanghai Henlius Biotech

Sex: All·Age: 18+

Code: NCT06532006·Phase 3·Recruiting·Listed Aug 2024

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Registry for Stage 2 Type 1 Diabetes

for Type 1 Diabetes

Sites in Chicago +36 more locations

Sponsor: Sanofi

Sex: All·Age: All ages

Code: NCT06481904·Recruiting·Listed Jul 2024

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Zenith® Fenestrated+ Clinical Study

for Aortic Aneurysm, Abdominal

Sites in Chicago, Glenview +28 more locations

Sponsor: Cook Research Incorporated

Sex: All·Age: 18+

Code: NCT04875429·Recruiting·Listed May 2021

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Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare

for Acute Gout Flare

Sites in Orland Park +15 more locations

Sponsor: Olatec Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05658575·Phase 2, Phase 3·Recruiting·Listed Dec 2022

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A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)

for Gastrointestinal Stromal Tumor (GIST)

Sites in Chicago +31 more locations

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06655246·Phase 1·Recruiting·Listed Oct 2024

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Endovascular AAA Intervention Using the GORE® EXCLUDER® Conformable AAA Endoprosthesis or Iliac Branch Endoprosthesis

for AAA - Abdominal Aortic Aneurysm

Sites in Chicago, Evanston +54 more locations

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT06218875·Recruiting·Listed Jan 2024

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A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Chicago, Maywood +42 more locations

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT05735184·Phase 1·Recruiting·Listed Feb 2023

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A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

for Hypothyroidism

Sites in Chicago +129 more locations

Sponsor: AbbVie

Sex: All·Age: 18 - 75

Code: NCT06345339·Phase 2, Phase 3·Recruiting·Listed Apr 2024

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A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Pediatric Participants With Nonsegmental Vitiligo

for NonSegmental Vitiligo

Drug: Ruxolitinib

Sites in Chicago, Skokie +67 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 2 - 11

Code: NCT06548360·Phase 3·Recruiting·Listed Aug 2024

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TEMPUS ARIES: A Biobank Registry Platform Study in Oncology

for Cancer

Sites in Peoria, O'Fallon +22 more locations

Sponsor: Tempus AI

Sex: All·Age: 18 - 99

Code: NCT06207032·Recruiting·Listed Jan 2024

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J-Valve Transfemoral Pivotal Study

for Aortic Valve Regurgitation

Sites in Chicago, Glenview +32 more locations

Sponsor: JC Medical, Inc., an affiliate of Edwards Lifesciences LLC

Sex: All·Age: 18+

Code: NCT06455787·Recruiting·Listed Jun 2024

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MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles

for Breast Cancer

Sites in Chicago, Oak Lawn +111 more locations

Sponsor: Agendia

Sex: All·Age: 18+

Code: NCT03053193·Recruiting·Listed Feb 2017

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A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03)

for Extensive Stage-small Cell Lung Cancer

Drug: Atezolizumab

Sites in Chicago +24 more locations

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06362252·Phase 1, Phase 2·Recruiting·Listed Apr 2024

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A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab

for Atopic Dermatitis

Drug: Upadacitinib

Sites in Chicago +65 more locations

Sponsor: AbbVie

Sex: All·Age: 18 - 63

Code: NCT06389136·Phase 3·Recruiting·Listed Apr 2024

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EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)

for Breast Cancer

Sites in Chicago +52 more locations

Sponsor: Exact Sciences Corporation

Sex: All·Age: 18+

Code: NCT06401421·Recruiting·Listed May 2024

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Trial to Evaluate the Safety and Effectiveness of Treatment With COMS One Device in Subjects With Diabetic Foot Ulcers

for Diabetic Foot Ulcer

Sites in Chicago, O'Fallon +24 more locations

Sponsor: Piomic Medical

Sex: All·Age: 22 - 90

Code: NCT05758545·Recruiting·Listed Mar 2023

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Study to Evaluate the Efficacy and Safety of Deuruxolitinib in Adolescents With Severe Alopecia Areata

for Alopecia Areata

Sites in Chicago +53 more locations

Sponsor: Sun Pharmaceutical Industries, Inc.

Sex: All·Age: 12 - 17

Code: NCT07133308·Phase 3·Recruiting·Listed Aug 2025

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A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease

for Inflammatory Bowel Disease (IBD)

Sites in Glenview, Gurnee +44 more locations

Sponsor: Mirador Therapeutics, Inc.

Sex: All·Age: 18 - 80

Code: NCT07113522·Phase 2·Recruiting·Listed Aug 2025

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Masupirdine for the Treatment of Agitation in Dementia of the Alzheimer's Type

for Agitation

Sites in Chicago +26 more locations

Sponsor: Suven Life Sciences Limited

Sex: All·Age: 50 - 90

Code: NCT05397639·Phase 3·Recruiting·Listed May 2022

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Caris Biorepository Research Protocol

for Cancer

Sites in Hinsdale +37 more locations

Sponsor: Caris Science, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT01499394·Recruiting·Listed Dec 2011

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A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)

for Chronic Graft-Versus-Host Disease (cGVHD)

Sites in Chicago +25 more locations

Sponsor: Deciphera Pharmaceuticals, LLC

Sex: All·Age: 18+

Code: NCT06619561·Phase 2·Recruiting·Listed Oct 2024

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PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR

for Aortic Stenosis, Calcific

Sites in Chicago, Lisle +48 more locations

Sponsor: Edwards Lifesciences

Sex: All·Age: 65+

Code: NCT04889872·Recruiting·Listed May 2021

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Autologous Hair Follicle Derived Secretome as Adjunct to Aesthetic Procedures

for Post Procedural Erythema

Sites in Chicago +19 more locations

Sponsor: Acorn Biolabs Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06477172·Recruiting·Listed Jun 2024

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US National OCS Heart Perfusion (OHP) Registry

for Heart Transplant

Sites in Chicago +36 more locations

Sponsor: TransMedics

Sex: All·Age: All ages

Code: NCT05915299·Recruiting·Listed Jun 2023

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Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)

for Acute Decompensated Heart Failure

Sites in Oak Lawn +36 more locations

Sponsor: Reprieve Cardiovascular, Inc

Sex: All·Age: 22+

Code: NCT06898515·Phase 3·Recruiting·Listed Mar 2025

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Real-world Experience Using Nemolizumab in the Treatment of Moderate-to-Severe Atopic Dermatitis in Adolescents & Adults

for Atopic Dermatitis

Drug: Nemolizumab

Sites in Chicago +57 more locations

Sponsor: Galderma R&D

Sex: All·Age: 12+

Code: NCT06988605·Recruiting·Listed May 2025

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A Study of Axatilimab at 3 Different Doses in Participants With Chronic Graft Versus Host Disease (cGVHD)

for Chronic Graft-versus-host-disease

Sites in Chicago +12 more locations

Sponsor: Syndax Pharmaceuticals

Sex: All·Age: 2+

Code: NCT04710576·Phase 2·Recruiting·Listed Jan 2021

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CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.

for Epithelial Ovarian Cancer

Sites in Chicago +25 more locations

Sponsor: TORL Biotherapeutics, LLC

Sex: Female·Age: 18+

Code: NCT06690775·Phase 2·Recruiting·Listed Nov 2024

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Metastatic Castrate-Resistant Prostate Cancer Subjects Treated With PROVENGE® + One Infusion of Sipuleucel-T

for Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Sites in Glenview, New Lenox +28 more locations

Sponsor: Dendreon

Sex: Male·Age: 18+

Code: NCT06134232·Phase 2·Recruiting·Listed Nov 2023

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(Peak) A Phase 3 Randomized Trial of CGT9486+Sunitinib vs. Sunitinib in Subjects With Gastrointestinal Stromal Tumors

for Advanced Gastrointestinal Stromal Tumors

Sites in Chicago +7 more locations

Sponsor: Cogent Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT05208047·Phase 3·Recruiting·Listed Jan 2022

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Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Esophagus

for Esophageal Stricture

Sites in Chicago +33 more locations

Sponsor: GIE Medical

Sex: All·Age: 22+

Code: NCT05561114·Phase 3·Recruiting·Listed Sep 2022

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Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Bowel

for Bowel

Sites in Chicago +32 more locations

Sponsor: GIE Medical

Sex: All·Age: 22+

Code: NCT05561127·Phase 3·Recruiting·Listed Sep 2022

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CAR-T Long Term Follow Up (LTFU) Study

for Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program

Sites in Chicago +40 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 0 - 100

Code: NCT02445222·Phase 3·Recruiting·Listed May 2015

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Tissue Repair Gel in Venous Leg Ulcers (US)

for Venous Leg Ulcer

Sites in Chicago, Springfield +25 more locations

Sponsor: TR Therapeutics

Sex: All·Age: 18+

Code: NCT06707090·Phase 3·Recruiting·Listed Nov 2024

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A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

for Treatment Resistant Depression

Sites in Chicago +33 more locations

Sponsor: atai Therapeutics, Inc.

Sex: All·Age: 18 - 65

Code: NCT06524830·Phase 2·Recruiting·Listed Jul 2024

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SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

for Cancer, Metastatic

Sites in Chicago +66 more locations

Sponsor: Massive Bio, Inc.

Sex: All·Age: All ages

Code: NCT03452774·Recruiting·Listed Mar 2018

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PARTNER 3 Trial - Aortic Valve-in-Valve

for Aortic Stenosis

Sites in Chicago +28 more locations

Sponsor: Edwards Lifesciences

Sex: All·Age: All ages

Code: NCT03003299·Recruiting·Listed Dec 2016

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A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis

for Uterine Fibroids

Drug: Relugolix

Sites in Chicago, Schaumburg +118 more locations

Sponsor: Sumitomo Pharma Switzerland GmbH

Sex: Female·Age: 18 - 50

Code: NCT05862272·Phase 3·Recruiting·Listed May 2023

Apply to this trial