A Study of MZE782 in Adults With PKU
for Phenylketonuria (PKU)
Sites in Indianapolis +1 more location
Sponsor: Maze Therapeutics
Sex: All·Age: 18 - 75
Code: NCT07694440·Phase 2·Recruiting·Listed Jul 10, 2026
Clinical Trials at Indiana University School of Medicine
As of August 2026, 36 paid clinical trials are recruiting at Indiana University School of Medicine, located at 545 BARNHILL DR, EMERSON HALL 203, INDIANAPOLIS, IN 46202-5112, phone (317) 274-5000 in Indianapolis, Indiana. Active studies at this site cover conditions such as Heart Failure, Obesity and Prostate Cancer. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
View the full facility profile →
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Filter results
Filter results
Newly added in Indianapolis
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
37 clinical trials at Indiana University School of Medicine
·Clear filters·A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition
for Metabolic Dysfunction-Associated SteatoHepatitis (MASH)
Sites in Indianapolis +36 more locations
Sponsor: Regeneron Pharmaceuticals
Sex: All·Age: 18 - 75
Code: NCT05519475·Phase 2·Recruiting·Listed Aug 2022
Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy
for Prostate Cancer
Sites in Indianapolis +26 more locations
Sponsor: Clarity Pharmaceuticals Ltd
Sex: Male·Age: 18+
Code: NCT06056830·Phase 3·Recruiting·Listed Sep 2023
A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Pediatric Participants With Nonsegmental Vitiligo
for NonSegmental Vitiligo
Drug: Ruxolitinib
Sites in Indianapolis +68 more locations
Sponsor: Incyte Corporation
Sex: All·Age: 2 - 11
Code: NCT06548360·Phase 3·Recruiting·Listed Aug 2024
Immune Modulation During Palynziq® Treatment in Adults (IMPALA)
for Phenylketonuria
Drug: Palynziq
Sites in Indianapolis +11 more locations
Sponsor: BioMarin Pharmaceutical
Sex: All·Age: 18 - 65
Code: NCT07477691·Phase 4·Recruiting·Listed Mar 2026
Long-term Characterization of GORE® TAG® Conformable Thoracic Stent Graft With ACTIVE CONTROL System Performance
for Vascular Disease
Sites in Indianapolis +23 more locations
Sponsor: W.L.Gore & Associates
Sex: All·Age: 18+
Code: NCT06658730·Recruiting·Listed Oct 2024
A Long-term, Post-marketing Safety Study of Palynziq in Patients With PKU (PALace)
for Phenylketonuria (PKU)
Drug: Palynziq
Sites in Indianapolis +11 more locations
Sponsor: BioMarin Pharmaceutical
Sex: All·Age: All ages
Code: NCT05813678·Recruiting·Listed Apr 2023
Blue Light Cystoscopy With Cysview® Registry
for Bladder Cancer
Sites in Indianapolis +20 more locations
Sponsor: Photocure
Sex: All·Age: 18+
Code: NCT02660645·Recruiting·Listed Jan 2016
A Study of Sepiapterin in Participants With Phenylketonuria (PKU)
for Phenylketonuria
1 location in Indianapolis
Sponsor: PTC Therapeutics
Sex: All·Age: Up to 9
Code: NCT06302348·Phase 3·Recruiting·Listed Mar 2024
Clinical Evaluation of BCDx for Monitoring of Recurrence in Non-Muscle Invasive Bladder Cancer
for Bladder Cancer
Sites in Indianapolis +2 more locations
Sponsor: Early is Good Inc.
Sex: All·Age: 18+
Code: NCT05982561·Recruiting·Listed Aug 2023
Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-101 in Participants With Myotonic Dystrophy Type 1
for Myotonic Dystrophy Type 1 (DM1)
Sites in Indianapolis +7 more locations
Sponsor: Dyne Therapeutics
Sex: All·Age: 18 - 65
Code: NCT05481879·Phase 1, Phase 2·Recruiting·Listed Aug 2022
A Single-arm, Pivotal Study to Evaluate Acute Device and Technical Success of the CGuard Prime Carotid Stent System When Used in Conjunction to the ENROUTE Transcarotid Neuroprotection System in Patients Undergoing Carotid Artery Stenting Via the Transcarotid Artery Revascularization Approach
for Carotid Artery Diseases
Sites in Indianapolis +7 more locations
Sponsor: InspireMD
Sex: All·Age: 18 - 79
Code: NCT06653387·Recruiting·Listed Oct 2024
Study to Assess the Use of Tezampanel for Opioid Withdrawal Syndrome in Treatment-Seeking Patients With Opioid Use Disorder
for Opioid Use Disorder
1 location in Indianapolis
Sponsor: Proniras Corporation
Sex: All·Age: 18 - 65
Code: NCT06538558·Phase 1·Recruiting·Listed Aug 2024
Neuroimaging of Adolescent Cannabis Use Treatment
for Cannabis Use
1 location in Indianapolis
Sponsor: Indiana University
Sex: All·Age: 14 - 17
Code: NCT07340554·Recruiting·Listed Jan 2026
Increasing Germline Genetic Testing for Patients With Cancer
for Hereditary Pancreatic Cancer
Sites in Indianapolis +9 more locations
Sponsor: Josh Peterson
Sex: All·Age: All ages·Accepts healthy volunteers
Code: NCT07307664·Recruiting·Listed Dec 2025
Measuring Patient Reported Needs in Outpatient Liver Disease Management
for Chronic Liver Disease
1 location in Indianapolis
Sponsor: Indiana University
Sex: All·Age: 18+
Code: NCT07191886·Recruiting·Listed Sep 2025
The New Empowerment After eXposure to Trauma (NEXT) Study
for PTSD - Post Traumatic Stress Disorder
1 location in Indianapolis
Sponsor: Indiana University
Sex: Female·Age: 18 - 50
Code: NCT07175025·Recruiting·Listed Sep 2025
A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
for Alzheimers Disease
Sites in Indianapolis +12 more locations
Sponsor: Washington University School of Medicine
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT06647498·Phase 2, Phase 3·Recruiting·Listed Oct 2024
A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
for Alzheimers Disease
Sites in Indianapolis +12 more locations
Sponsor: Washington University School of Medicine
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT05552157·Phase 2, Phase 3·Recruiting·Listed Sep 2022
Bionic Pancreas in CFRD
for Cystic Fibrosis-related Diabetes
Sites in Indianapolis +14 more locations
Sponsor: Jaeb Center for Health Research
Sex: All·Age: 14+
Code: NCT06449677·Phase 3·Recruiting·Listed Jun 2024
The Prevalence of Neuropathic Pain Pathophysiology Associated With Ankle Fracture
for Neuropathic Pain
1 location in Indianapolis
Sponsor: Indiana University
Sex: All·Age: 18 - 85·Accepts healthy volunteers
Code: NCT06420141·Recruiting·Listed May 2024
Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)
for Acute Myeloid Leukemia
Drug: Venetoclax
Sites in Indianapolis +44 more locations
Sponsor: PedAL BCU, LLC
Sex: All·Age: 29 Days - 21
Code: NCT05183035·Phase 3·Recruiting·Listed Jan 2022
Survivorship Plan HEalth REcord (SPHERE) Implementation Trial
for Cancer
1 location in Indianapolis
Sponsor: Indiana University
Sex: All·Age: 18 - 99·Accepts healthy volunteers
Code: NCT05346796·Recruiting·Listed Apr 2022
Molecular Genetics of Heterotaxy and Related Congenital Heart Defects
for Heterotaxy Syndrome
1 location in Indianapolis
Sponsor: Indiana University
Sex: All·Age: All ages
Code: NCT02432079·Recruiting·Listed May 2015
Effect of the HCC Liver-Link Intervention
for HCC
Sites in Indianapolis +1 more location
Sponsor: Indiana University
Sex: All·Age: 18 - 75
Code: NCT06728293·Recruiting·Listed Dec 2024
Adapted CBT-I for Adolescents With Insomnia : The DREAM-IT Study
for Insomnia
1 location in Indianapolis
Sponsor: Indiana University
Sex: All·Age: 13 - 18
Code: NCT06541886·Recruiting·Listed Aug 2024
Campath/Fludarabine/Melphalan Transplant Conditioning for Non-Malignant Diseases
for Metabolic Disorders
Sites in Indianapolis +11 more locations
Sponsor: Washington University School of Medicine
Sex: All·Age: Up to 20
Code: NCT00920972·Phase 1, Phase 2·Recruiting·Listed Jun 2009
Family Support Protocol for Adolescent Internalizing Disorders
for Internalizing Disorders
Sites in Indianapolis +3 more locations
Sponsor: The National Center on Addiction and Substance Abuse at Columbia University
Sex: All·Age: 13 - 21
Code: NCT06413979·Recruiting·Listed May 2024
Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil Disorders
for Periodic Fever, Aphthous Stomatitis, Pharyngitis, And Cervical Adenitis (Pfapa)
Sites in Indianapolis +2 more locations
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Sex: All·Age: 1 Month - 99
Code: NCT05656365·Recruiting·Listed Dec 2022
Fecal Microbiota Transplant National Registry
for Fecal Microbiota Transplantation
Sites in Indianapolis +27 more locations
Sponsor: American Gastroenterological Association
Sex: All·Age: All ages
Code: NCT03325855·Recruiting·Listed Oct 2017
Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry
for Rheumatic Joint Disease
Sites in Indianapolis +67 more locations
Sponsor: Duke University
Sex: All·Age: Up to 21
Code: NCT02418442·Recruiting·Listed Apr 2015
Maternal Newborn Health Registry
for Pregnancy Outcome Trends in Low-resource Geographic Areas
Sites in Indianapolis +7 more locations
Sponsor: NICHD Global Network for Women's and Children's Health
Sex: All·Age: All ages·Accepts healthy volunteers
Code: NCT01073475·Recruiting·Listed Feb 2010
Registering Genomics and Imaging of Tumors (ReGIT)
for Glioma
1 location in Indianapolis
Sponsor: Indiana University
Sex: All·Age: 18+
Code: NCT05386043·Recruiting·Listed May 2022
Interaction of CYP2B6 Genotype and Efavirenz With Methadone and Tizanidine PK
for Drug-Drug Interaction
1 location in Indianapolis
Sponsor: Indiana University
Sex: All·Age: 18 - 65·Accepts healthy volunteers
Code: NCT05789173·EARLY_Phase 1·Recruiting·Listed Mar 2023
The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action
for Type 1 Diabetes
1 location in Indianapolis
Sponsor: Heba M. Ismail
Sex: All·Age: 11 - 18
Code: NCT05414409·Phase 2·Recruiting·Listed Jun 2022
Master Protocol for Evaluating Multiple Infection Diagnostics for Ciprofloxacin-Resistant Neisseria Gonorrhoeae
for Neisseria Gonorrheae Infection
Sites in Indianapolis +7 more locations
Sponsor: Duke University
Sex: All·Age: All ages
Code: NCT06815536·Recruiting·Listed Feb 2025
Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections
for Pulmonary Invasive Fungal Infections
Sites in Indianapolis +26 more locations
Sponsor: Arkansas Children's Hospital Research Institute
Sex: All·Age: 120 Days - 21
Code: NCT03827694·Recruiting·Listed Feb 2019
Common conditions studied in Indianapolis
- Heart Failure (15 active studies)
- Obesity (14 active studies)
- Prostate Cancer (11 active studies)
- Dementia (10 active studies)
- Multiple Myeloma (10 active studies)
- Acute Myeloid Leukemia (8 active studies)
Leading research sponsors in Indianapolis
- Indiana University
- Eli Lilly and Company
- National Cancer Institute (NCI)
- Children's Oncology Group
- Janssen Research & Development, LLC
Frequently asked questions
How many paid clinical trials are currently recruiting in Indianapolis?
There are approximately 867 recruiting clinical trials in Indianapolis, Indiana listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Indianapolis pay participants?
Most recruiting trials in Indianapolis compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Indianapolis?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Indianapolis?
The most common conditions under active study in Indianapolis include Heart Failure (15), Obesity (14), Prostate Cancer (11), Dementia (10), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Indianapolis?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Indianapolis on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Indianapolis?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Indianapolis?
Recruiting research sites in Indianapolis include Indiana University, Riley Hospital for Children, Indiana University School of Medicine, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Indianapolis right now?
The largest active categories in Indianapolis are Cancer & tumors (225), Cardiovascular (66), Diabetes & metabolic (53). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of Indiana University School of Medicine?
Indiana University School of Medicine is located at 545 BARNHILL DR, EMERSON HALL 203, INDIANAPOLIS, IN 46202-5112. Use the Google Maps link in the intro above to get directions.
How do I contact Indiana University School of Medicine?
You can reach Indiana University School of Medicine by phone at (317) 274-5000. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.
Browse more clinical trials
Other cities in Indiana
Fort Wayne, IN(103)Carmel, IN(72)Crown Point, IN(50)Munster, IN(50)Bloomington, IN(48)Dyer, IN(38)New Albany, IN(38)Valparaiso, IN(34)Hobart, IN(30)Richmond, IN(30)South Bend, IN(30)Evansville, IN(27)West Lafayette, IN(27)Goshen, IN(17)Muncie, IN(16)Hammond, IN(14)Avon, IN(13)Merrillville, IN(13)Plainfield, IN(12)Newburgh, IN(11)Jeffersonville, IN(9)Elkhart, IN(8)Lafayette, IN(8)Mooresville, IN(8)Clarksville, IN(7)Greenwood, IN(7)Fishers, IN(6)Michigan City, IN(5)Mishawaka, IN(5)Noblesville, IN(5)Notre Dame, IN(5)Brownsburg, IN(3)Greenfield, IN(3)Kokomo, IN(3)Columbus, IN(2)Franklin, IN(2)Granger, IN(2)New Castle, IN(2)Westfield, IN(2)Anderson, IN(1)Ellettsville, IN(1)Forest Hill, IN(1)Frankfort, IN(1)Gary, IN(1)Indianappolis, IN(1)Indianopolis, IN(1)Indianpolis, IN(1)La Porte, IN(1)Lebanon, IN(1)Monroe, IN(1)Nationwide, IN(1)Princeton, IN(1)Royal Center, IN(1)Terre Haute, IN(1)Vincennes, IN(1)