Paid Clinical Trials in Iowa City, IA

As of June 2026, 591 paid clinical trials are recruiting in Iowa City, Iowa. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 29, 2026.

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592 clinical trials

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A Study to Test Whether BI 3802876 is Tolerated in People With Compensated Liver Cirrhosis Due to Metabolic Dysfunction- Associated Steatohepatitis (MASH)

for Liver Cirrhosis

Drug: BI 3802876

26 locations incl. Chandler

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18 - 75

Code: NCT07325526·Phase 2·Recruiting

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A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4)

for Relapsed Refractory Multiple Myeloma

48 locations incl. Gilbert

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07391657·Phase 3·Recruiting

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Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD

for Chronic Obstructive Pulmonary Disease (COPD)

Drug: Omalizumab

23 locations incl. Birmingham

Sponsor: Johns Hopkins University

Sex: All·Age: 40+

Code: NCT07059091·Phase 2·Recruiting

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5-Azacitidine Plus PD-1/PD-L1 Inhibitor With PD-1/PD-L1 Refractory Tumors

for Solid Tumor

1 location in Iowa City

Sponsor: Mohammed Milhem

Sex: All·Age: 18 - 99

Code: NCT07404332·Phase 1·Recruiting

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A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

29 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07266441·Phase 2·Recruiting

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A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

23 locations incl. Los Angeles

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07258511·Phase 3·Recruiting

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Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)

for Hepatitis

Drug: Larsucosterol

48 locations incl. Birmingham

Sponsor: Bausch Health Americas, Inc.

Sex: All·Age: 18+

Code: NCT07428538·Phase 3·Recruiting

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A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma

for Eosinophilic Asthma

20 locations incl. Long Beach

Sponsor: Kymera Therapeutics, Inc.

Sex: All·Age: 18 - 75

Code: NCT07323654·Phase 2·Recruiting

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Delay AvoIding Primary Evaluation for ThRombectomy of Acute StrokE Patients With Large Vessel OCclusion in the Angiography SuiTe

for Stroke, Acute

6 locations incl. Iowa City

Sponsor: Santiago Ortega Gutierrez

Sex: All·Age: 18+

Code: NCT06825897·Recruiting

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Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

for Advanced Endometrial Carcinoma

Drug: Bevacizumab

221 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT07198074·Phase 3·Recruiting

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TulmiSTAR-02: A Phase I/II Open-label Study of Tulmimetostat in Combination With Darolutamide vs. Darolutamide, and Tulmimetostat With Abiraterone in Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

for Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)

Drug: Tulmimetostat

8 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18+

Code: NCT07190300·Phase 1, Phase 2·Recruiting

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A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy

for Large B-cell Lymphoma

38 locations incl. Gilbert

Sponsor: Lyell Immunopharma, Inc.

Sex: All·Age: 18+

Code: NCT07188558·Phase 3·Recruiting

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A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults

for Diabetes Mellitus, Type 1

Drug: Baricitinib

7 locations incl. Tallahassee

Sponsor: Eli Lilly and Company

Sex: All·Age: 1 - 35

Code: NCT07222137·Phase 3·Recruiting

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AB-3028, a Programmable Circuit T Cell Therapy in Patients With Castration Resistant Prostate Cancer (CRPC)

for Metastatic Castration Resistant Prostate Cancer (mCRPC)

9 locations incl. Duarte

Sponsor: Arsenal Biosciences, Inc.

Sex: Male·Age: 18+

Code: NCT07285694·Phase 1, Phase 2·Recruiting

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Beeline: A Phase 3 Study in GRIN-related Neurodevelopmental Disorder

for GRIN-related Neurodevelopmental Disorder

17 locations incl. Los Angeles

Sponsor: GRIN Therapeutics, Inc.

Sex: All·Age: 1 Month - 18

Code: NCT07224581·Phase 3·Recruiting

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Combined Local Anesthetic Blockade and Neuromodulation vs Local Anesthetic Blockade Only for Analgesia After Below-knee Amputation: RCT

for Amputation

3 locations incl. Stanford

Sponsor: Stanford University

Sex: All·Age: 18+

Code: NCT06964347·Not Yet Recruiting

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer

for Untreated, Unresectable, or Metastatic Colorectal Cancer

Drug: Bevacizumab

49 locations incl. Tucson

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07221357·Phase 2, Phase 3·Recruiting

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Aerodynamic Measurements in the Pediatric Population

for Normal Voice

2 locations incl. Iowa City

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 4 - 65·Accepts healthy volunteers

Code: NCT06975046·Recruiting

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A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

for Breast Neoplasms

118 locations incl. Anchorage

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07174336·Phase 3·Recruiting

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A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy

for Spinal Muscular Atrophy (SMA)

17 locations incl. Little Rock

Sponsor: argenx

Sex: All·Age: 5 - 17

Code: NCT07287982·Phase 2·Recruiting

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The Effects of Footplate Stiffness on Foot Loading Within Carbon Fiber Custom Dynamic Orthoses

for Trauma Injury

1 location in Iowa City

Sponsor: Jason Wilken

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07312032·Recruiting

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NV PSR INSPIRE-A Pipeline™ Vantage Post Approval Study

for Intracranial Aneurysm

7 locations incl. Jacksonville

Sponsor: Medtronic Neurovascular Clinical Affairs

Sex: All·Age: 22+

Code: NCT06604884·Recruiting

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Study of RYZ401 in Subjects With Solid Tumors Expressing SSTRs.

for GEP-NET

7 locations incl. Iowa City

Sponsor: RayzeBio, Inc.

Sex: All·Age: 18+

Code: NCT07165132·Phase 1·Recruiting

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Effect of Donor Diabetes and Other Factors on Corneal Transplant Endothelial Cell Loss and Success at 5 Years

for Fuchs Endothelial Corneal Dystrophy

14 locations incl. Atlanta

Sponsor: Case Western Reserve University

Sex: All·Age: 30 - 93

Code: NCT07217249·Enrolling By Invitation

A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy

for Gastrointestinal Neoplasms

36 locations incl. Phoenix

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT07218926·Phase 3·Recruiting

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Creating Health Course Study for People With Rheumatological Conditions

for Rheumatoid Arthritis

1 location in Iowa City

Sponsor: Terry L. Wahls

Sex: All·Age: 18 - 100

Code: NCT07180537·Recruiting

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Investigating Mediodorsal Thalamus Representations Underlying Human Cognitive Flexibility

for Schizophrenia

1 location in Iowa City

Sponsor: Kai Hwang

Sex: All·Age: 18 - 35·Accepts healthy volunteers

Code: NCT07217652·Recruiting

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A Study to Assess the Safety and Efficacy of LB-P8 in Patients With PSC

for Primary Sclerosing Cholangitis (PSC)

7 locations incl. Sacramento

Sponsor: LISCure Biosciences

Sex: All·Age: 18 - 75

Code: NCT06699121·Phase 2·Recruiting

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A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)

for Small-cell Lung Cancer

31 locations incl. La Jolla

Sponsor: Zai Lab (Shanghai) Co., Ltd.

Sex: All·Age: 18+

Code: NCT07218146·Phase 3·Recruiting

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Zymfentra (Infliximab-dyyb) REal World Cohort STudy

for Ulcerative Colitis (UC)

9 locations incl. New Haven

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18+

Code: NCT07237516·Recruiting

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Genetic Risk Factor for Heat Stroke

for Carrier State

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 60

Code: NCT06847256·Recruiting

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Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen

for Carcinoid Syndrome

17 locations incl. Gilbert

Sponsor: Crinetics Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT07087054·Phase 3·Recruiting

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Phase 2a Study of VX-407 in Participants With ADPKD Who Have a Subset of PKD1 Gene Variants (AGLOW)

for Autosomal Dominant Polycystic Kidney Disease (ADPKD)

26 locations incl. Alabaster

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 65

Code: NCT07161037·Phase 2·Recruiting

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A Study to Find Out Whether BI 765423 Has an Effect on Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF) With or Without Standard Treatment

for Idiopathic Pulmonary Fibrosis

Drug: BI 765423

15 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 40+

Code: NCT07036523·Phase 2·Recruiting

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A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

for Systemic Lupus Erythematosus (With and Without Nephritis)

13 locations incl. Phoenix

Sponsor: Allogene Therapeutics

Sex: All·Age: 18 - 69

Code: NCT07085104·Phase 1·Recruiting

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A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

for Ovarian Cancer

Drug: INCB123667

42 locations incl. Mobile

Sponsor: Incyte Corporation

Sex: Female·Age: 18 - 99

Code: NCT07023627·Phase 2·Recruiting

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Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia

for B-cell Acute Lymphoblastic Leukemia (B-ALL)

6 locations incl. Duarte

Sponsor: AstraZeneca

Sex: All·Age: 12+

Code: NCT07109219·Phase 1, Phase 2·Recruiting

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Impact of Anatomy-Based Cochlear Implant Programming on Early Performance

for Hearing Loss, Unilateral

6 locations incl. Iowa City

Sponsor: Med-El Corporation

Sex: All·Age: 18+

Code: NCT06734039·Enrolling By Invitation

A Long-Term Study of Bivamelagon in Participants With Hypothalamic Obesity (HO)

for Hypothalamic Obesity

6 locations incl. Aurora

Sponsor: Rhythm Pharmaceuticals, Inc.

Sex: All·Age: 12+

Code: NCT07156578·Phase 2·Enrolling By Invitation

Ketorolac Use and Fresh Embryo Transfer Outcomes

for Infertility (IVF Patients)

1 location in Iowa City

Sponsor: Jessica D. Kresowik

Sex: Female·Age: 18 - 37

Code: NCT07185724·Phase 4·Recruiting

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