Paid Clinical Trials in Iowa City, IA

As of September 2026, 549 paid clinical trials are recruiting in Iowa City, Iowa. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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505 clinical trials

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A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

for Crohn's Disease

Sites in Iowa City +25 more locations

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT06233461·Phase 2·Recruiting·Listed Jan 2024

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A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)

for Type 2 Diabetes

Drug: Dulaglutide

Sites in Iowa City +40 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 10 - 17

Code: NCT06739122·Phase 3·Recruiting·Listed Dec 2024

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A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer

for Advanced Breast Cancer

Sites in Iowa City +36 more locations

Sponsor: Stemline Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06638307·Phase 1·Recruiting·Listed Oct 2024

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Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

for Heart Failure - NYHA II - IV

Sites in Iowa City +39 more locations

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07069738·Recruiting·Listed Jul 2025

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A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis

for Non-cystic Fibrosis Bronchiectasis

Sites in Iowa City +27 more locations

Sponsor: Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA

Sex: All·Age: 18 - 80

Code: NCT06559150·Phase 2·Recruiting·Listed Aug 2024

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GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study

for Stroke

Sites in Iowa City, West Des Moines +29 more locations

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18 - 70

Code: NCT03821129·Recruiting·Listed Jan 2019

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VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

for Advanced Melanoma

Drug: Nivolumab

Sites in Iowa City +43 more locations

Sponsor: Replimune, Inc.

Sex: All·Age: 12+

Code: NCT06264180·Phase 3·Recruiting·Listed Feb 2024

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SELUTION 4 De Novo Small Vessel IDE Trial

for Coronary Artery Disease

Sites in Iowa City +63 more locations

Sponsor: M.A. Med Alliance S.A.

Sex: All·Age: 18+

Code: NCT05946629·Recruiting·Listed Jul 2023

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Neutrophil and Monocyte Deactivation Via the SeLective CytopheretIc Device - A Randomized Clinical Trial in Acute Kidney Injury

for Acute Kidney Injury

Sites in Iowa City +31 more locations

Sponsor: SeaStar Medical

Sex: All·Age: 18+

Code: NCT05758077·Recruiting·Listed Mar 2023

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Pompe Disease Registry Protocol

for Glycogen Storage Disease Type II

Sites in Iowa City +73 more locations

Sponsor: Genzyme, a Sanofi Company

Sex: All·Age: All ages

Code: NCT00231400·Recruiting·Listed Oct 2005

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First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

for Breast Cancer

Sites in Iowa City +23 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT05768139·Phase 1, Phase 2·Recruiting·Listed Mar 2023

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Study to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of a Modified Regimen of Ublituximab

for Relapsing Multiple Sclerosis

Sites in Iowa City +38 more locations

Sponsor: TG Therapeutics, Inc.

Sex: All·Age: 18 - 65

Code: NCT05877963·Phase 3·Recruiting·Listed May 2023

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Fabry Disease Registry & Pregnancy Sub-registry

for Fabry Disease

Sites in Iowa City +73 more locations

Sponsor: Genzyme, a Sanofi Company

Sex: All·Age: All ages

Code: NCT00196742·Recruiting·Listed Sep 2005

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A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus

Sites in Iowa City +61 more locations

Sponsor: UCB Biopharma SRL

Sex: All·Age: 16+

Code: NCT06617325·Phase 3·Recruiting·Listed Sep 2024

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A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

for Carcinoma, Non-Small-Cell Lung

Sites in Iowa City +24 more locations

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT05208762·Phase 1·Recruiting·Listed Jan 2022

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A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

for Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis

Sites in Iowa City +132 more locations

Sponsor: 89bio, Inc.

Sex: All·Age: 18 - 75

Code: NCT06419374·Phase 3·Recruiting·Listed May 2024

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A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis

Sites in Iowa City +137 more locations

Sponsor: 89bio, Inc.

Sex: All·Age: 18 - 80

Code: NCT06318169·Phase 3·Recruiting·Listed Mar 2024

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Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

for Heart Failure

Sites in Iowa City +56 more locations

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT06526195·Recruiting·Listed Jul 2024

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AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.

for Refractory Rheumatoid Arthritis (RA)

Drug: Rituximab

Sites in Iowa City +30 more locations

Sponsor: Artiva Biotherapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06991114·Phase 2·Recruiting·Listed May 2025

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REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE

for Aortic Stenosis

Sites in Iowa City, Des Moines +69 more locations

Sponsor: Medtronic Cardiovascular

Sex: All·Age: 18 - 105

Code: NCT06777368·Recruiting·Listed Jan 2025

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Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))

for Mesial Temporal Lobe Epilepsy

Sites in Iowa City +34 more locations

Sponsor: Neurona Therapeutics

Sex: All·Age: 18 - 75

Code: NCT05135091·Phase 3·Recruiting·Listed Nov 2021

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A Study to Compare the Efficacy and Safety of Golcadomide in Combination With Rituximab (Golca + R) vs Investigator's Choice in Participants With Relapsed/Refractory Follicular Lymphoma Who Have Received at Least 1 Prior Line of Systemic Therapy (GOLSEEK-4)

for Follicular Lymphoma

Drug: Golcadomide

Sites in Iowa City, Waukee +29 more locations

Sponsor: Celgene

Sex: All·Age: 18+

Code: NCT06911502·Phase 3·Recruiting·Listed Apr 2025

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Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

for Alpha1-Antitrypsin Deficiency

Sites in Iowa City +32 more locations

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT05677971·Phase 3·Recruiting·Listed Jan 2023

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Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease

for Moderately to Severely Active Crohn Disease

Sites in Iowa City +42 more locations

Sponsor: Abivax S.A.

Sex: All·Age: 18 - 75

Code: NCT06456593·Phase 2·Recruiting·Listed Jun 2024

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International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

for Gaucher Disease

Sites in Iowa City +69 more locations

Sponsor: Genzyme, a Sanofi Company

Sex: All·Age: All ages

Code: NCT00358943·Recruiting·Listed Aug 2006

Apply to this trial

GEMINI-NSCLC: NSCLC Biomarker Study

for Non-Small Cell Lung Cancer

Sites in Iowa City +55 more locations

Sponsor: Tempus AI

Sex: All·Age: 18+

Code: NCT05236114·Recruiting·Listed Feb 2022

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A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer

for Gastroesophageal-junction Cancer

Sites in Iowa City, Des Moines +27 more locations

Sponsor: Shanghai Henlius Biotech

Sex: All·Age: 18+

Code: NCT06532006·Phase 3·Recruiting·Listed Aug 2024

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A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

for Metastatic Uveal Melanoma

Drug: Nivolumab

Sites in Iowa City +28 more locations

Sponsor: Replimune, Inc.

Sex: All·Age: All ages

Code: NCT06581406·Phase 2, Phase 3·Recruiting·Listed Sep 2024

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A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)

for Gastrointestinal Stromal Tumor (GIST)

Sites in Iowa City +31 more locations

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06655246·Phase 1·Recruiting·Listed Oct 2024

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A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Iowa City +43 more locations

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT05735184·Phase 1·Recruiting·Listed Feb 2023

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Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

Sites in Iowa City +37 more locations

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT06297226·Phase 2·Recruiting·Listed Mar 2024

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Study of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy

for GEP-NET

Sites in Iowa City +12 more locations

Sponsor: RayzeBio, Inc.

Sex: All·Age: 18+

Code: NCT05477576·Phase 3·Recruiting·Listed Jul 2022

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Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs)

for Generalized Myasthenia Gravis

Sites in Iowa City +31 more locations

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT04202341·Recruiting·Listed Dec 2019

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Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

for Spinal Muscular Atrophy (SMA)

Sites in Iowa City +41 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: All ages

Code: NCT04174157·Recruiting·Listed Nov 2019

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SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

for Cancer, Metastatic

Sites in Iowa City +66 more locations

Sponsor: Massive Bio, Inc.

Sex: All·Age: All ages

Code: NCT03452774·Recruiting·Listed Mar 2018

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A Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature

for Idiopathic Short Stature

Drug: Vosoritide

Sites in Iowa City +30 more locations

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 3 - 11

Code: NCT06382155·Phase 2·Recruiting·Listed Apr 2024

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A Study Comparing JNJ-79635322 and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

Drug: Teclistamab

Sites in Iowa City, Waukee +33 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07518186·Phase 3·Recruiting·Listed Apr 2026

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KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GIST in 1st Line Setting (SynerGIST-1st Line)

for GIST - Gastrointestinal Stromal Tumor

Sites in Iowa City +16 more locations

Sponsor: Kumquat Biosciences Inc.

Sex: All·Age: 18+

Code: NCT07406633·Phase 2·Recruiting·Listed Feb 2026

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A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease

for Huntington Disease

Sites in Iowa City +39 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 21 - 70

Code: NCT07326709·Phase 3·Recruiting·Listed Jan 2026

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A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy

for Spinal Muscular Atrophy (SMA)

Sites in Iowa City +14 more locations

Sponsor: argenx

Sex: All·Age: 5 - 17

Code: NCT07287982·Phase 2·Recruiting·Listed Dec 2025

Apply to this trial