Clinical Trials at East Tennessee Childrens Hospital
As of August 2026, 26 paid clinical trials are recruiting at East Tennessee Childrens Hospital, located at 137 E BLOUNT AVE, KNOXVILLE, TN 37920-1601, phone (865) 632-5011 in Knoxville, Tennessee. Active studies at this site cover conditions such as Acute Myeloid Leukemia, Obesity and Breast Cancer. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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26 clinical trials at East Tennessee Childrens Hospital
·Clear filters·A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations
A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)
Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia
Project: Every Child for Younger Patients With Cancer
A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis
A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)
A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT
A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)
A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma
The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study
Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma
A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma
Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma
Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)
A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT
Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia
A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia
A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss
A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma
Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma
A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)
A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study
A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS)
Common conditions studied in Knoxville
- Acute Myeloid Leukemia (8 active studies)
- Obesity (7 active studies)
- Breast Cancer (6 active studies)
- Carcinoma, Non-Small-Cell Lung (5 active studies)
- Hypertension (5 active studies)
- Overweight (4 active studies)
Leading research sponsors in Knoxville
- Children's Oncology Group
- National Cancer Institute (NCI)
- Merck Sharp & Dohme LLC
- University of Tennessee Graduate School of Medicine
- AstraZeneca
Frequently asked questions
How many paid clinical trials are currently recruiting in Knoxville?
There are approximately 220 recruiting clinical trials in Knoxville, Tennessee listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Knoxville pay participants?
Most recruiting trials in Knoxville compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Knoxville?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Knoxville?
The most common conditions under active study in Knoxville include Acute Myeloid Leukemia (8), Obesity (7), Breast Cancer (6), Carcinoma, Non-Small-Cell Lung (5), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Knoxville?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Knoxville on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Knoxville?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Knoxville?
Recruiting research sites in Knoxville include University of Tennessee Medical Center, East Tennessee Childrens Hospital, University of Tennessee - Knoxville, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Knoxville right now?
The largest active categories in Knoxville are Cancer & tumors (92), Cardiovascular (17), Diabetes & metabolic (15). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of East Tennessee Childrens Hospital?
East Tennessee Childrens Hospital is located at 137 E BLOUNT AVE, KNOXVILLE, TN 37920-1601. Use the Google Maps link in the intro above to get directions.
How do I contact East Tennessee Childrens Hospital?
You can reach East Tennessee Childrens Hospital by phone at (865) 632-5011. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.