Non-invasive Prediction of EArly Cardiac rEjection
for Heart Transplant
Sites in Little Rock +21 more locations
Sponsor: Vanderbilt University Medical Center
Sex: All·Age: 6 - 25
Code: NCT07770659·Recruiting·Listed Aug 18, 2026
Clinical Trials at Arkansas Children's Hospital
As of September 2026, 87 paid clinical trials are recruiting at Arkansas Children's Hospital, located at 1 CHILDRENS WAY, SLOT 664, LITTLE ROCK, AR 72202-3500, phone (501) 364-2526 in Little Rock, Arkansas. Active studies at this site cover conditions such as Schizophrenia, Acute Myeloid Leukemia and Duchenne Muscular Dystrophy. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Little Rock
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
88 clinical trials at Arkansas Children's Hospital
·Clear filters· Get a weekly email when new trials open in Little Rock, AR.
A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease
for Sickle Cell Disease
Drug: Etavopivat
Sites in Little Rock +43 more locations
Sponsor: Novo Nordisk A/S
Sex: All·Age: 12+
Code: NCT06612268·Phase 3·Recruiting·Listed Sep 2024
A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome
for Dravet Syndrome
Sites in Little Rock +20 more locations
Sponsor: Epygenix
Sex: All·Age: 2+
Code: NCT04462770·Phase 3·Recruiting·Listed Jul 2020
Pompe Disease Registry Protocol
for Glycogen Storage Disease Type II
Sites in Little Rock +73 more locations
Sponsor: Genzyme, a Sanofi Company
Sex: All·Age: All ages
Code: NCT00231400·Recruiting·Listed Oct 2005
Fabry Disease Registry & Pregnancy Sub-registry
for Fabry Disease
Sites in Little Rock +73 more locations
Sponsor: Genzyme, a Sanofi Company
Sex: All·Age: All ages
Code: NCT00196742·Recruiting·Listed Sep 2005
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction
for Complex Congenital Heart Defect
Sites in Little Rock +20 more locations
Sponsor: Edwards Lifesciences
Sex: All·Age: All ages
Code: NCT02744677·Recruiting·Listed Apr 2016
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry
for Gaucher Disease
Sites in Little Rock +69 more locations
Sponsor: Genzyme, a Sanofi Company
Sex: All·Age: All ages
Code: NCT00358943·Recruiting·Listed Aug 2006
Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)
for Spinal Muscular Atrophy (SMA)
Sites in Little Rock +41 more locations
Sponsor: Novartis Pharmaceuticals
Sex: All·Age: All ages
Code: NCT04174157·Recruiting·Listed Nov 2019
A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy
for Spinal Muscular Atrophy (SMA)
Sites in Little Rock +14 more locations
Sponsor: argenx
Sex: All·Age: 5 - 17
Code: NCT07287982·Phase 2·Recruiting·Listed Dec 2025
A Phase 2 Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation (The ReInspire Study)
for PIK3CA-Related Overgrowth Spectrum (PROS)
Sites in Little Rock +21 more locations
Sponsor: Relay Therapeutics, Inc.
Sex: All·Age: 2+
Code: NCT06789913·Phase 2·Recruiting·Listed Jan 2025
A Study of SGT-003 Gene Therapy in Duchenne Muscular Dystrophy (INSPIRE DUCHENNE)
for Duchenne Muscular Dystrophy
Sites in Little Rock +11 more locations
Sponsor: Solid Biosciences Inc.
Sex: Male·Age: 0 - 17
Code: NCT06138639·Phase 1, Phase 2·Recruiting·Listed Nov 2023
A Study to Assess Adverse Events, Change in Disease Activity, and How the Drug Moves Through the Body in Children With Juvenile Psoriatic Arthritis (jPsA) Receiving Subcutaneously Injected Risankizumab or Adalimumab
for Juvenile Psoriatic Arthritis
Drug: Risankizumab
Sites in Little Rock +11 more locations
Sponsor: AbbVie
Sex: All·Age: 5 - 17
Code: NCT06100744·Phase 3·Recruiting·Listed Oct 2023
A Study Assessing HMB-002 in Participants With Von Willebrand Disease
for Von Willebrand Disease (VWD)
Sites in Little Rock +12 more locations
Sponsor: Hemab ApS
Sex: All·Age: 16 - 69
Code: NCT06754852·Phase 1, Phase 2·Recruiting·Listed Jan 2025
A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's Disease
for Crohn's Disease
Drug: Risankizumab
Sites in Little Rock +10 more locations
Sponsor: AbbVie
Sex: All·Age: 2 - 17
Code: NCT05995353·Phase 3·Recruiting·Listed Aug 2023
Study to Evaluate Subcutaneous (SC) VGA039 in Patients With Von Willebrand Disease (VWD)
for Von Willebrand Disease (VWD)
Sites in Little Rock +10 more locations
Sponsor: Vega Therapeutics, Inc
Sex: All·Age: 12 - 75
Code: NCT07115004·Phase 3·Recruiting·Listed Aug 2025
A Study of Bleeding and Treatment in Participants With Von Willebrand Disease
for Von Willebrand Disease (VWD)
Sites in Little Rock +12 more locations
Sponsor: Hemab ApS
Sex: All·Age: 16+
Code: NCT06610201·Recruiting·Listed Sep 2024
A Study to Learn About the Study Medicine Called Zavegepant (PF-07930207) in Children With a History of Migraine
for Acute Treatment of Migraine
Sites in Little Rock +12 more locations
Sponsor: Pfizer
Sex: All·Age: 6 - 11
Code: NCT06995729·Phase 1·Recruiting·Listed May 2025
Safety and Efficacy of Tideglusib in Congenital or Childhood Onset Myotonic Dystrophy
for Congenital Myotonic Dystrophy
Sites in Little Rock +7 more locations
Sponsor: AMO Pharma Limited
Sex: All·Age: 6 - 45
Code: NCT05004129·Phase 2, Phase 3·Recruiting·Listed Aug 2021
Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy
for Cardiomyopathy
Sites in Little Rock +20 more locations
Sponsor: Tenaya Therapeutics
Sex: All·Age: 0 - 18
Code: NCT05112237·Recruiting·Listed Nov 2021
PBGENE-DMD Phase 1/2a Safety and Preliminary Efficacy Study in Duchenne Muscular Dystrophy (FUNCTION-DMD)
for Duchenne Muscular Dystrophy With Mutations Amenable to PBGENE-DMD
Sites in Little Rock +1 more location
Sponsor: Precision BioSciences, Inc.
Sex: Male·Age: 2 - 7
Code: NCT07429240·Phase 1, Phase 2·Recruiting·Listed Feb 2026
A Study of SGT-003 Gene Therapy in Ambulant Males With Duchenne Muscular Dystrophy (IMPACT DUCHENNE)
for Duchenne Muscular Dystrophy
Sites in Little Rock +2 more locations
Sponsor: Solid Biosciences Inc.
Sex: Male·Age: 7 - 11
Code: NCT07160634·Phase 3·Recruiting·Listed Sep 2025
A Gene Transfer Therapy Study to Evaluate the Safety of and Expression From Delandistrogene Moxeparvovec (SRP-9001) in Participants With Duchenne Muscular Dystrophy (DMD) - Non-Ambulatory Cohort
for Duchenne Muscular Dystrophy
Sites in Little Rock +5 more locations
Sponsor: Sarepta Therapeutics, Inc.
Sex: Male·Age: 2+
Code: NCT04626674·Phase 1·Recruiting·Listed Nov 2020
A Study of Patients With Fabry Disease (US Specific)
for Fabry Disease
Sites in Little Rock +7 more locations
Sponsor: Amicus Therapeutics
Sex: All·Age: 18+
Code: NCT06906367·Recruiting·Listed Apr 2025
Study to Assess the Safety, Tolerability, and Preliminary Efficacy of ST266 in Infants With Necrotizing Enterocolitis (NEC)
for Necrotizing Enterocolitis
Sites in Little Rock +7 more locations
Sponsor: Noveome Biotherapeutics, formerly Stemnion
Sex: All·Age: 2 Weeks - 8 Weeks
Code: NCT06315738·Phase 1, Phase 2·Recruiting·Listed Mar 2024
A Study to Evaluate Ferumoxytol for the Treatment of Iron Deficiency Anemia (IDA) in Pediatric Subjects
for Iron Deficiency Anemia
Sites in Little Rock +5 more locations
Sponsor: AMAG Pharmaceuticals, Inc.
Sex: All·Age: 2 - 17
Code: NCT03893045·Phase 3·Recruiting·Listed Mar 2019
Open-label Study of WVE-N531 in Patients With Duchenne Muscular Dystrophy (FORWARD-53)
for Duchenne Muscular Dystrophy
Sites in Little Rock +1 more location
Sponsor: Wave Life Sciences USA, Inc.
Sex: Male·Age: 4 - 18
Code: NCT04906460·Phase 1, Phase 2·Recruiting·Listed May 2021
ASC618 Gene Therapy in Hemophilia A Patients
for Hemophilia A
1 location in Little Rock
Sponsor: ASC Therapeutics
Sex: Male·Age: 18+
Code: NCT04676048·Phase 1, Phase 2·Recruiting·Listed Dec 2020
Duchenne Electronic Health Record Study
for Duchenne Muscular Dystrophy (DMD)
Sites in Little Rock +9 more locations
Sponsor: The Duchenne Registry
Sex: All·Age: All ages
Code: NCT07609394·Recruiting·Listed May 2026
Mitochondrial Energy Metabolism in Burns
for Burn Injury
1 location in Little Rock
Sponsor: Arkansas Children's Hospital Research Institute
Sex: All·Age: 2 - 80
Code: NCT07643545·Recruiting·Listed Jun 2026
Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
for Childhood Extracranial Germ Cell Tumor
Sites in Little Rock +381 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: All ages
Code: NCT03067181·Phase 3·Recruiting·Listed Mar 2017
A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab
for Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8
Drug: Nivolumab
Sites in Little Rock +379 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 5 - 60
Code: NCT05675410·Phase 3·Recruiting·Listed Jan 2023
Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer
for Hematopoietic and Lymphatic System Neoplasm
Sites in Little Rock, Fort Smith +189 more locations
Sponsor: Children's Oncology Group
Sex: Female·Age: Up to 39
Code: NCT06513962·Phase 3·Recruiting·Listed Jul 2024
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy
for B Acute Lymphoblastic Leukemia
Sites in Little Rock +186 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: 365 Days - 25
Code: NCT03959085·Phase 3·Recruiting·Listed May 2019
A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)
for B Acute Lymphoblastic Leukemia
Sites in Little Rock +137 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 366 Days - 46
Code: NCT06124157·Phase 2·Recruiting·Listed Nov 2023
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations
for Acute Myeloid Leukemia
Sites in Little Rock +168 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: Up to 21
Code: NCT04293562·Phase 3·Recruiting·Listed Mar 2020
Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia
for Acute Leukemia of Ambiguous Lineage
Drug: Venetoclax
Sites in Little Rock +111 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: Up to 365 Days
Code: NCT06317662·Phase 2·Recruiting·Listed Mar 2024
A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis
for Recurrent Langerhans Cell Histiocytosis
Sites in Little Rock +100 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 180 Days - 22
Code: NCT05828069·Phase 2·Recruiting·Listed Apr 2023
Project: Every Child for Younger Patients With Cancer
for Adrenal Gland Pheochromocytoma
Sites in Little Rock +226 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: Up to 25
Code: NCT02402244·Recruiting·Listed Mar 2015
A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)
for Stage I Mixed Cell Type Kidney Wilms Tumor
Sites in Little Rock +152 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: Up to 30
Code: NCT06401330·Phase 3·Recruiting·Listed May 2024
A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT
for Anaplastic Kidney Wilms Tumor
Sites in Little Rock +171 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: Up to 30
Code: NCT04322318·Phase 2·Recruiting·Listed Mar 2020
A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)
for Malignant Glioma
Drug: Selinexor
Sites in Little Rock +105 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 12 Months - 21
Code: NCT05099003·Phase 1, Phase 2·Recruiting·Listed Oct 2021
Common conditions studied in Little Rock
- Schizophrenia (16 active studies)
- Acute Myeloid Leukemia (11 active studies)
- Duchenne Muscular Dystrophy (10 active studies)
- Malignant Solid Neoplasm (8 active studies)
- Obesity (8 active studies)
- Bipolar I Disorder (7 active studies)
Leading research sponsors in Little Rock
- University of Arkansas
- National Cancer Institute (NCI)
- Arkansas Children's Hospital Research Institute
- Children's Oncology Group
- SWOG Cancer Research Network
Frequently asked questions
How many paid clinical trials are currently recruiting in Little Rock?
There are approximately 501 recruiting clinical trials in Little Rock, Arkansas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Little Rock pay participants?
Most recruiting trials in Little Rock compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Little Rock?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Little Rock?
The most common conditions under active study in Little Rock include Schizophrenia (16), Acute Myeloid Leukemia (11), Duchenne Muscular Dystrophy (10), Malignant Solid Neoplasm (8), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Little Rock?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Little Rock on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Little Rock?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Little Rock?
Recruiting research sites in Little Rock include University of Arkansas for Medical Sciences, Arkansas Children's Hospital, CARTI Cancer Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Little Rock right now?
The largest active categories in Little Rock are Cancer & tumors (133), Mental health & behavior (38), Cardiovascular (30). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of Arkansas Children's Hospital?
Arkansas Children's Hospital is located at 1 CHILDRENS WAY, SLOT 664, LITTLE ROCK, AR 72202-3500. Use the Google Maps link in the intro above to get directions.
How do I contact Arkansas Children's Hospital?
You can reach Arkansas Children's Hospital by phone at (501) 364-2526. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.
Browse more clinical trials
Other cities in Arkansas
Jonesboro, AR(83)Springdale, AR(66)Fayetteville, AR(59)Rogers, AR(52)Fort Smith, AR(51)Hot Springs, AR(22)North Little Rock, AR(19)Bryant, AR(17)Bentonville, AR(11)Arkansas City, AR(4)Conway, AR(3)Searcy, AR(3)Pine Bluff, AR(2)Sherwood, AR(2)West Memphis, AR(2)Blytheville, AR(1)Corning, AR(1)El Dorado, AR(1)Fairbanks, AR(1)Glenwood, AR(1)Harrisburg, AR(1)Harrison, AR(1)Lavaca, AR(1)Marianna, AR(1)Marshall, AR(1)Monticello, AR(1)Mountain Home, AR(1)Osceola, AR(1)Siloam Springs, AR(1)Texarkana, AR(1)Washington, AR(1)White Hall, AR(1)