Paid Clinical Trials in Massachusetts

Massachusetts has 3,586 paid clinical trials enrolling now across cities including Boston, Worcester and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Massachusetts include Mass General Hospital, Dana-Farber and Brigham and Women's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

Filter results

Filter results

State

City

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

3,586 clinical trials

↓ Download CSV

A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis

for Secondary Progressive Multiple Sclerosis

12 locations incl. Phoenix

Sponsor: Zenas BioPharma (USA), LLC

Sex: All·Age: 18 - 60

Code: NCT07299019·Phase 3·Recruiting

Apply to this trial

Extension Study for Participants in Studies That Include Belzutifan (MK-6482-043/LITESPARK-043)

for Von Hippel-Lindau Disease

4 locations incl. Boston

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07405164·Phase 3·Recruiting

Apply to this trial

Cardiac Effects of Mineralocorticoid Receptor Antagonism After Preeclampsia

for Hypertension

2 locations incl. Boston

Sponsor: Massachusetts General Hospital

Sex: Female·Age: 18 - 65

Code: NCT07238400·Phase 2·Recruiting

Apply to this trial

Study in Advanced Solid Tumor Patients

for Advanced Solid Tumor

5 locations incl. Boston

Sponsor: Callio Therapeutics

Sex: All·Age: 18+

Code: NCT07300943·Phase 1, Phase 2·Recruiting

Apply to this trial

A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1

for HIV

8 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07390955·Phase 1·Recruiting

Apply to this trial

Reversal of Spinal Anesthesia Residual Motor Block Via Intrathecal Catheter

for Joint Replacement Surgery

1 location in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: All ages

Code: NCT07404982·Phase 2·Recruiting

Apply to this trial

Dose Ranging Study of ORKA-002 in Patients With Moderate-to-Severe Plaque Psoriasis

for Plaque Psoriasis

22 locations incl. Birmingham

Sponsor: Oruka Therapeutics, Inc.

Sex: All·Age: 18 - 79

Code: NCT07474792·Phase 2·Recruiting

Apply to this trial

Phase 2/3 Clinical Study of QRX003 Lotion in Subjects With Netherton Syndrome

for Netherton Syndrome

5 locations incl. Fremont

Sponsor: Quoin Pharmaceuticals

Sex: All·Age: 4+

Code: NCT07538583·Phase 2, Phase 3·Recruiting

Apply to this trial

Assessment of Microvascular Circulation in the Pediatric Cardiac Surgery Patient

for Tetrology of Fallot

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 1 Day - 17

Code: NCT07184476·Recruiting

Apply to this trial

Neurocognitive Function Changes With Extended-Release Tacrolimus Among Older Kidney Transplant Recipients

for Kidney Transplant Recipients

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 65+

Code: NCT06751992·Phase 4·Recruiting

Apply to this trial

A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT

for Adenovirus Infections

26 locations incl. Phoenix

Sponsor: SymBio Pharmaceuticals

Sex: All·Age: 2 Months+

Code: NCT07387367·Phase 3·Recruiting

Apply to this trial

Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention

for HIV Infections

17 locations incl. Beverly Hills

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT07473778·Recruiting

Apply to this trial

CAIX PET/CT for Residual or Recurrent Post-ablative ccRCC

for Clear Cell Renal Cell Carcinoma (ccRCC)

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07077083·Phase 2·Not Yet Recruiting

The Use of p48/64 MW HPC Flow Modulation Device in the Treatment of Wide-necked Intracranial Aneurysms

for Hemorrhagic Stroke

17 locations incl. Phoenix

Sponsor: phenox Inc.

Sex: All·Age: 18+

Code: NCT07143019·Recruiting

Apply to this trial

Tacrolimus Ophthalmic Solution for the Treatment of Non-infectious Anterior Uveitis

for Non-infectious Anterior Uveitis

5 locations incl. Miami

Sponsor: Novaliq GmbH

Sex: All·Age: 18+

Code: NCT07285070·Phase 2·Recruiting

Apply to this trial

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

for Obesity or Overweight

Drug: Enicepatide

25 locations incl. Anniston

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07351045·Phase 3·Recruiting

Apply to this trial

A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)

for Non-small Cell Lung Cancer (NSCLC)

Drug: Durvalumab

38 locations incl. Daphne

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07361497·Phase 3·Recruiting

Apply to this trial

Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine Use (Pilot Study)

for Nicotine Dependence

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 65

Code: NCT07145866·Phase 4·Not Yet Recruiting

Assessing MB-Spirit for Psychological Well-being

for Stress

2 locations incl. Boston

Sponsor: Sara W Lazar

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT07325448·Recruiting

Apply to this trial

Stepped Care for Posttraumatic Stress Disorder Study

for Post Traumatic Stress Disorder

1 location in Boston

Sponsor: Boston Medical Center

Sex: All·Age: 18+

Code: NCT06947538·Recruiting

Apply to this trial

Yoga for Persistent Post-Surgical Pain (PPSP)

for Persistent Post-surgical Pain

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT06949007·Recruiting

Apply to this trial

Delirium in Neurodegenerative Disease Patients: A Music Therapy Intervention for Hospital Care

for Delirium

1 location in Boston

Sponsor: Boston Medical Center

Sex: All·Age: 60+

Code: NCT07137949·Recruiting

Apply to this trial

On-Trac: An Online Intervention for Cancer Survivors Managing Anxiety

for Cancer

1 location in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT07305740·Recruiting

Apply to this trial

Virtual Reality for Caregiver Assembly, Relief, Empowerment, and Support (VR-CARES)

for Direct Care Workers

6 locations incl. San Diego

Sponsor: Rendever, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07430371·Recruiting

Apply to this trial

Synaptic Mechanisms of Continuous Theta Burst Stimulation in Depression

for Major Depression

1 location in Belmont

Sponsor: Mclean Hospital

Sex: All·Age: 18+

Code: NCT07560878·EARLY_Phase 1·Recruiting

Apply to this trial

Kisspeptin to Quantify GnRH Neuronal Function in Health and Disease

for Reproductive Disorder

1 location in Boston

Sponsor: Stephanie B. Seminara, MD

Sex: All·Age: 18 - 60

Code: NCT07224490·Phase 1·Recruiting

Apply to this trial

BILe Acid-gut Microbiome Axis MODification Through Diet Education for Colorectal Cancer Prevention

for Colorectal Cancer Prevention

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 80

Code: NCT07162337·Recruiting

Apply to this trial

PDT For Induction Therapy For Head And Neck Cancer

for Squamous Cell Carcinoma

2 locations incl. Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07214987·Phase 2·Not Yet Recruiting

Pre-NEOSHIFT-RCC: Neoadjuvant HIF-Inhibitor Immunotherapy in RCC

for Renal Cell Carcinoma

3 locations incl. Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT07397611·Phase 2·Recruiting

Apply to this trial

A Study to Investigate Efficacy and Safety of FWY003 Compared With Placebo in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration

for Geographic Atrophy Secondary to Age-related Macular Degeneration

Drug: FWY003

12 locations incl. Huntington Beach

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 50+

Code: NCT07441642·Phase 2·Recruiting

Apply to this trial

Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

for Pancreatic Cancer

Drug: daraxonrasib

5 locations incl. Baltimore

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT07491445·Phase 3·Recruiting

Apply to this trial

A Study to Evaluate Safety and Efficacy of TP-05 in Healthy Participants With Tick Exposure

for Lyme Disease

19 locations incl. Pikesville

Sponsor: Tarsus Pharmaceuticals, Inc.

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT07562087·Phase 2·Recruiting

Apply to this trial

A First-in-human Study of RLY-8161 in Advanced NRAS-Mutant Solid Tumors

for Advanced NRAS-Mutant Melanoma

6 locations incl. Los Angeles

Sponsor: Relay Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07584226·Phase 1·Recruiting

Apply to this trial

Ketamine add-on Therapy for Established Status Epilepticus Treatment Trial (KESETT)

for Status Epilepticus

52 locations incl. Tucson

Sponsor: University of Virginia

Sex: All·Age: 1+

Code: NCT06907173·Phase 3·Recruiting

Apply to this trial

Delivering tAN to Reduce HMB: The LUNA Study

for Heavy Menstrual Bleeding

1 location in Boston

Sponsor: Spark Biomedical, Inc.

Sex: Female·Age: 14 - 45

Code: NCT07326722·Recruiting

Apply to this trial

Exploring the Effects of Brief Mindfulness Training With Vagal Nerve Stimulation on Alcohol Cue Reactivity Among Young Adult Heavy Drinkers

for Heavy Drinking

1 location in Malden

Sponsor: Cambridge Health Alliance

Sex: All·Age: 21 - 29

Code: NCT07516873·Recruiting

Apply to this trial

Self-Help Cognitive Processing Therapy (CPT)/Women Veterans Network (WoVeN) Study

for Posttraumatic Stress Disorder

1 location in Boston

Sponsor: Boston University

Sex: Female·Age: 18+

Code: NCT07250061·Recruiting

Apply to this trial

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

for CRC (Colorectal Cancer)

Drug: Bevacizumab

80 locations incl. Chandler

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07284849·Phase 3·Recruiting

Apply to this trial

A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT1988 in Participants at Clinical High Risk for Psychosis

for Clinical High Risk for Psychosis (CHR)

15 locations incl. Irvine

Sponsor: Monument Therapeutics Limited

Sex: All·Age: 17 - 30

Code: NCT07226895·Phase 1, Phase 2·Recruiting

Apply to this trial

Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)

for Open Angle Glaucoma (OAG)

4 locations incl. Glendale

Sponsor: Life Biosciences Inc.

Sex: All·Age: 40 - 85

Code: NCT07290244·Phase 1·Recruiting

Apply to this trial