A Study to Evaluate Solrikitug in Participants With COPD (ZION)

Part of paid clinical trials in Birmingham, Alabama.

Sponsor
Uniquity One (UNI)
Study ID
NCT06496620
Phase
PHASE2
Status
Active Not Recruiting

Conditions

Eligibility Criteria

Sex
ALL
Age
40 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • Biological: Solrikitug low dose — BIOLOGICAL
    Solrikitug subcutaneous injection
  • Biological: Solrikitug high dose — BIOLOGICAL
    Solrikitug subcutaneous injection
  • Placebo — OTHER
    Placebo subcutaneous injection

Study Details

A Randomized, Double-blind, Placebo-controlled, Multiple Dose-Ranging Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Solrikitug in Participants with Chronic Obstructive Pulmonary Disease (COPD).

Key Dates

First listed
Jul 11, 2024
Start date
Aug 14, 2024
Status verified
Aug 2026
Primary completion
Sep 30, 2026
Completion
Feb 1, 2027

Study Design

Enrollment
182 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Biological: Solrikitug High Dose
    Solrikitug
  • Other: Placebo
    Placebo
  • Experimental: Biological: Solrikitug Low Dose
    Solrikitug

Primary Outcome Measure

Change from baseline in blood eosinophil counts [ Time Frame: Through week 12 ]

Locations (94)

FacilityCityStateZIPSite coordinators
University of Alabama at Birmingham HospitalBirminghamAlabama35294-
Syed Research ConsultantsSheffieldAlabama35660-
Phoenix Medical GroupPeoriaArizona85381-
Epic Medical Research-SurpriseSun CityArizona85351-
Alliance for Multispecialty ResearchTempeArizona85281-
Novak Clinical ResearchTucsonArizona85741-
Antelope Valley Clinical TrialsLancasterCalifornia93534-
Ark Clinical Research - BallingerLong BeachCalifornia90815-
Downtown LA Research Center, Inc.Los AngelesCalifornia90017-
Newport Native MD, Inc.Newport BeachCalifornia92663-
OM ResearchOxnardCalifornia93036-
Prospective Research Innovations, Inc.Rancho CucamongaCalifornia91730-
Velocity Clinical Research - DenverEnglewoodColorado80110-
Access Research InstituteBrooksvilleFlorida34613-
Clinical Research of West Florida - ClearwaterClearwaterFlorida33765-
Innovative Research of West Florida, Inc.ClearwaterFlorida33756-
JY Research InstituteCutler BayFlorida33189-
Hillcrest Medical Research, LLCDeLandFlorida32720-
Direct Helper Research CenterHialeahFlorida33012-
Homestead Associates in Research Inc.HomesteadFlorida33033-
AppleMed Research Group, LLCMiamiFlorida33126-
Coral Research Clinic CorporationMiamiFlorida33186-
De La Cruz Research Center, LLCMiamiFlorida33184-
Reliant Medical Research LLCMiamiFlorida33165-
Valencia Medical & Research CenterMiamiFlorida33174-
Y&L Advanced Health Care, Inc.MiamiFlorida33144-
Pro-Care Research Center, Corp.Miami GardensFlorida33014-
San Marcus Research Clinic, Inc.Miami LakesFlorida33014-
Florida Institute for Clinical ResearchOrlandoFlorida32825-
Sarasota Clinical ResearchSarasotaFlorida34239-
TBC ResearchTamaracFlorida33321-
Clinical Research of West Florida - TampaTampaFlorida33606-
Appalachian Clinical Research, LLCAdairsvilleGeorgia30103-
Pulmonology, Sleep, Asthma, and Allergy Center - DublinDublinGeorgia31021-
CPCC - Research, LLCEast PointGeorgia30344-
Centricity ResearchRinconGeorgia31326-
Velocity Clinical Research - BoiseMeridianIdaho83642-
OSF HealthCare Saint Francis Medical CenterPeoriaIllinois61606-
Indiana Medical Research InstituteMerrillvilleIndiana46410-
The Research Group of Lexington, LLCLexingtonKentucky40503-
Tandem Clinical ResearchMetairieLouisiana70006-
Care Access - ShreveportShreveportLouisiana71105-
Mayflower ClinicalSouth DartmouthMassachusetts02747-
Revival Research Institute, LLCDearbornMichigan48126-
Henry Ford Health SystemDetroitMichigan48207-
Pulmonary Research Institute of SE MichiganFarmington HillsMichigan48336-
Revive Research InstituteSouthfieldMichigan48075-
Midwest Chest ConsultantsSaint CharlesMissouri63301-
Montana Medical Research, Inc.MissoulaMontana59808-
Henderson TrialsHendersonNevada89052-
Rutgers, The State University of New JersyNew BrunswickNew Jersey08901-
Certified Research Associates Finger Lakes Medical Research, LLCCortlandNew York13045-
Corning Center for Clinical Research Smith Allergy & Asthma SpecialistsHorseheadsNew York14845-
OnSite Clinical SolutionsCharlotteNorth Carolina28277-
Clinical Research of GastoniaGastoniaNorth Carolina28054-
Triad Clinical TrialsGreensboroNorth Carolina27410-
Peters Medical ResearchHigh PointNorth Carolina27260-
Advanced Respiratory and Sleep MedicineHuntersvilleNorth Carolina28078-
Accellacare WilmingtonWilmingtonNorth Carolina28401-
Southeastern Research CenterWinston-SalemNorth Carolina27103-
Remington DavisColumbusOhio43215-
NexGen ResearchLimaOhio45801-
OK Clinical ResearchEdmondOklahoma73034-
Velocity Clinical Research - Grants PassGrants PassOregon97257-
Velocity Clinical Research - MedfordMedfordOregon97504-
Clinical Research Associates of Central PADuBoisPennsylvania15801-
Temple UniversityPhiladelphiaPennsylvania19140-
Allergy and Clinical Immunology AssociatesPittsburghPennsylvania15241-
University of Pittsburgh/UPMCPittsburghPennsylvania15213-
AnMed HealthAndersonSouth Carolina29621-
Velocity Clinical Research - AndersonAndersonSouth Carolina29621-
Medical University of South CarolinaCharlestonSouth Carolina29245-
Velocity Clinical Research - ColumbiaColumbiaSouth Carolina29204-
Velocity Clinical Research - GaffneyGaffneySouth Carolina29340-
Velocity Clinical Research - GreenvilleGreenvilleSouth Carolina29615-
Clinical Research of Rock HillRock HillSouth Carolina29732-
Velocity Clinical Research - SpartanburgSpartanburgSouth Carolina29303-
Velocity Clinical Research - UnionUnionSouth Carolina29379-
Pulmonary & Sleep SpecialistsDicksonTennessee37055-
Premier Research Center, LLCHendersonvilleTennessee37075-
New Phase Research & DevelopmentKnoxvilleTennessee37909-
TTS ResearchBoerneTexas78006-
Proactive RGVBrownsvilleTexas78520-
Ten20 Clinical Research, LLCCarrolltonTexas75010-
IntraCare Health CenterDallasTexas75254-
IntraCare ClinicalGreenvilleTexas75401-
Axsendo Clinical ResearchHoustonTexas77030-
Gulf Coast Clinical ResearchHoustonTexas77070-
R & H Clinical ResearchKatyTexas77494-
IntraCare Health CenterMcKinneyTexas75071-
SMS Clinical ResearchMesquiteTexas75149-
ADP Clinical ResearchSplendoraTexas77372-
Alpine Research Organization, Inc.LaytonUtah84041-
Velocity Clinical Research - HamptonHamptonVirginia23666-

Find similar trials in Birmingham, AL

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By condition
COPD
By specialty
PulmonologyLung disease
By research site
University of Alabama at Birmingham Hospital· Birmingham, ALSyed Research Consultants· Sheffield, ALPhoenix Medical Group· Peoria, AZEpic Medical Research-Surprise· Sun City, AZAlliance for Multispecialty Research· Tempe, AZNovak Clinical Research· Tucson, AZ

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