Paid Clinical Trials in Massachusetts

Massachusetts has 3,586 paid clinical trials enrolling now across cities including Boston, Worcester and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Massachusetts include Mass General Hospital, Dana-Farber and Brigham and Women's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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3,586 clinical trials

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Effects of Estrogen on Heart Health in Women With Primary Ovarian Insufficiency

for Primary Ovarian Insufficiency

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: Female·Age: 30 - 40·Accepts healthy volunteers

Code: NCT06866119·Not Yet Recruiting

Finding Links Between Hot flASHes and CardioVascular Disease

for Menopause-related Hot Flashes

2 locations incl. Boston

Sponsor: Massachusetts General Hospital

Sex: Female·Age: 40 - 65

Code: NCT07077395·Phase 2·Recruiting

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Real-World Study of Foslevodopa/Foscarbidopa to Assess Quality of Life Outcomes in Adult Participants Earlier Within Advanced Parkinson Disease

for Parkinson's Disease

1 location in Boston

Sponsor: AbbVie

Sex: All·Age: 18 - 80

Code: NCT07227896·Not Yet Recruiting

Hoffa's Fat Pad Impingement (HFPI)

for Hoffa's Fat Pad Impingement

1 location in Norwood

Sponsor: Boston Children's Hospital

Sex: Female·Age: 12 - 18

Code: NCT07255248·Phase 4·Recruiting

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Resilient Families Feasibility Trial

for Parents

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07383948·Not Yet Recruiting

Balancing Emotions and Electronics: A Pilot Intervention for Preschoolers

for Screen Media Use

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 30 Months - 54 Months·Accepts healthy volunteers

Code: NCT07394166·Recruiting

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Robotic Opioid-free Prostatectomy Enhanced Strategy (ROPES)

for Opioid Consumption, Postoperative

2 locations incl. Boston

Sponsor: Brigham and Women's Hospital

Sex: Male·Age: 45+

Code: NCT07427043·Phase 3·Recruiting

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Plasma and Radiologic Biomarkers of Response to ECP in Lung Transplant Recipients With CLAD

for Lung Transplant Failure and Rejection

3 locations incl. Boston

Sponsor: Brian Keller

Sex: All·Age: 7+

Code: NCT07434869·Not Yet Recruiting

KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases

for Mitochondrial Diseases

3 locations incl. Boston

Sponsor: Khondrion BV

Sex: All·Age: 18+

Code: NCT06451757·Phase 3·Recruiting

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Mindfulness Meditation for Insomnia

for Sleep Initiation and Maintenance Disorders

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT06972303·Phase 1, Phase 2·Recruiting

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Treating Young Children With Attention Deficit Hyperactivity Disorder

for Attention-Deficit/Hyperactivity Disorder (ADHD)

5 locations incl. Palo Alto

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 3 - 5

Code: NCT07300956·Phase 4·Not Yet Recruiting

Optimal Timing of Ketamine Initiation for SCD Pain

for Sickle Cell Disease

1 location in Brookline

Sponsor: Boston Children's Hospital

Sex: All·Age: 6 - 24

Code: NCT07450430·Phase 3·Not Yet Recruiting

Brain Stimulation for Foot-sole Sensation in Older Adults With Foot-sole Somatosensory Deficits

for Somatosensory Function

1 location in Roslindale

Sponsor: Hebrew SeniorLife

Sex: All·Age: 65+

Code: NCT06771531·Recruiting

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Mindfulness ADHD Intervention

for Attention Deficit Hyperactivity Disorder (ADHD)

1 location in Brookline

Sponsor: Boston Children's Hospital

Sex: All·Age: 7 - 11

Code: NCT07037030·Enrolling By Invitation

LiverSleep: A Behavioral Sleep Intervention for Patients With Cirrhosis and Insomnia

for Cirrhosis

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07417163·Recruiting

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Comparison of the Effects of Oral Hygiene Regimens on Clinical, Immunomodulatory, and Microbial Outcomes and Oral Tolerance in People With Gingivitis

for Microbiome

1 location in Somerville

Sponsor: Kenvue Brands LLC

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT07501455·Recruiting

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Oncoplastic Surgery Outcomes Database

for Breast Cancer

2 locations incl. Boston

Sponsor: Tufts Medical Center

Sex: Female·Age: 18+

Code: NCT07597837·Recruiting

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Testing Effectiveness of a Stochastic Noise Stimulator to Immediately Improve Balance and Gait

for Vestibular Disorder

2 locations incl. Baltimore

Sponsor: Massachusetts Eye and Ear Infirmary

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT06688578·Recruiting

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Intravascular Neuro OCT Imaging System for Aneurysm Treatment Evaluation

for Intracranial Aneurysm

6 locations incl. Jacksonville

Sponsor: Spryte Medical

Sex: All·Age: 18 - 75

Code: NCT07214220·Recruiting

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A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations

for Parkinson Disease

25 locations incl. Little Rock

Sponsor: Appello Pharmaceuticals, Inc.

Sex: All·Age: 30 - 80

Code: NCT07432958·Phase 2·Recruiting

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Pathways, Risk Factors, and mOleculeS to Prevent Early-onset Colorectal Tumors

for Colorectal Cancer Prevention

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 50

Code: NCT07095517·Phase 1·Recruiting

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SARC046: A Phase II Trial of Nab-Sirolimus in Patients With Progressing or Symptomatic Epithelioid Hemangioendothelioma

for Epithelioid Hemangioendothelioma (EHE)

6 locations incl. Stanford

Sponsor: Sarcoma Alliance for Research through Collaboration

Sex: All·Age: 18+

Code: NCT07104331·Phase 2·Recruiting

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Long-acting Cabotegravir Injectable Pre-exposure Prophylaxis for People Who Inject Drugs

for HIV

2 locations incl. Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07199335·Phase 4·Recruiting

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Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use

for Depression - Major Depressive Disorder

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06878859·Recruiting

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iNO300 Therapy in Critically Ill Patients With Pneumonia

for Critical Illness

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06950294·EARLY_Phase 1·Recruiting

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PK, Safety and Preliminary Efficacy Study of Montelukast in Critically Ill Infants With Developing Bronchopulmonary Dysplasia

for Bronchopulmonary Dysplasia (BPD)

5 locations incl. Little Rock

Sponsor: Duke University

Sex: All·Age: 7 Days - 28 Days

Code: NCT07101640·Phase 1, Phase 2·Recruiting

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Momelotinib During and After HCT in Myelofibrosis

for Myelofibrosis

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07104799·Phase 1·Recruiting

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A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)

for Catecholaminergic Polymorphic Ventricular Tachycardia

4 locations incl. Boston

Sponsor: Solid Biosciences Inc.

Sex: All·Age: 7+

Code: NCT07148089·Phase 1·Recruiting

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REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool

for PTSD - Post Traumatic Stress Disorder

5 locations incl. Aurora

Sponsor: Senseye, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07280065·Phase 3·Recruiting

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A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4)

for Relapsed Refractory Multiple Myeloma

48 locations incl. Gilbert

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07391657·Phase 3·Recruiting

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An Open-Label Extension Study of ORKA-001 in Participants With Plaque Psoriasis

for Plaque Psoriasis

16 locations incl. Fountain Valley

Sponsor: Oruka Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07449702·Phase 2·Recruiting

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Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical Cancer

for Locally Advanced Adrenal Cortical Carcinoma

Drug: Cabozantinib

69 locations incl. La Jolla

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12+

Code: NCT06900595·Phase 2·Recruiting

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A Self-Directed Web-Based Education for Boston Marathon Runners With Patellofemoral Pain

for Patellofemoral Pain

1 location in Waltham

Sponsor: Boston Children's Hospital

Sex: All·Age: 18 - 45

Code: NCT07266922·Enrolling By Invitation

An Empowering Parent Training Intervention to Increase Physical Activity in Preschool Aged Children With Autism

for Autism Spectrum Disorder (ASD)

1 location in Boston

Sponsor: Northeastern University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07421830·Recruiting

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A Clinical Trial Comparing 2x/Day for 30-minutes Use of the Emanate Perio PODS Post-SRP to a Control Group Post-SRP.

for Periodontitis (Stage 3)

9 locations incl. Fullerton

Sponsor: McGuire Institute

Sex: All·Age: 30 - 75

Code: NCT06914596·Recruiting

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A Clinical Study to Evaluate the Efficacy and Safety of Ultra in Promoting Hair Regrowth

for Androgenic Alopecia

2 locations incl. Glenview

Sponsor: CynosureLutronic

Sex: All·Age: 22 - 70

Code: NCT07588243·Recruiting

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A Study to Assess the Effectiveness and Safety of IPN10200 Over Time in Adults With Moderate to Severe Wrinkle-like Lines Between the Eyebrows

for Moderate to Severe Glabellar Lines

41 locations incl. Los Angeles

Sponsor: Ipsen

Sex: All·Age: 18 - 80

Code: NCT07435428·Phase 3·Recruiting

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Investigating Subcortical Contributions to Speech Sequencing in Deep Brain Stimulator Recipients

for Parkinson's Disease (PD)

2 locations incl. Boston

Sponsor: Boston University Charles River Campus

Sex: All·Age: 18+

Code: NCT07455760·Recruiting

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A Study for the PanCystPro Assay in the Management of Pancreatic Cystic Lesions

for Pancreatic Cystic Lesions

3 locations incl. Indianapolis

Sponsor: Amplified Sciences Inc

Sex: All·Age: 18+

Code: NCT06894329·Recruiting

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A Study to Find Out if BI 764198 Helps Adults and Adolescents With a Kidney Condition Called Focal Segmental Glomerulosclerosis (FSGS)

for Focal Segmental Glomerulosclerosis

65 locations incl. Alabaster

Sponsor: Boehringer Ingelheim

Sex: All·Age: 12+

Code: NCT07220083·Phase 3·Recruiting

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