Paid Clinical Trials in Massachusetts

Massachusetts has 3,446 paid clinical trials enrolling now across cities including Boston, Worcester and Burlington. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Massachusetts include Mass General Hospital, Dana-Farber and Brigham and Women's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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Healthy volunteers only

2,953 clinical trials

Dose-escalation and Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Participants With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)

for Non-Hodgkin Lymphoma

Sites in Boston +9 more locations

Sponsor: Imugene Limited

Sex: All·Age: 18+

Code: NCT03666000·Phase 1·Recruiting·Listed Sep 2018

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A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease

for End Stage Renal Disease (ESRD)

Sites in Boston +19 more locations

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18 - 90

Code: NCT04671771·Recruiting·Listed Dec 2020

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Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years

for Motor Function

Sites in Boston +7 more locations

Sponsor: Guerbet

Sex: All·Age: 18 - 64

Code: NCT04373564·Phase 4·Recruiting·Listed May 2020

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A Phase 1/3 Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation

for AML

Sites in Boston +20 more locations

Sponsor: TScan Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05473910·Phase 1·Recruiting·Listed Jul 2022

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A Prospective Sub-Study of the Global Hypophosphatasia Registry

for Hypophosphatasia

Sites in Boston +11 more locations

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: All ages

Code: NCT05234567·Recruiting·Listed Feb 2022

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A Phase 1 Study of LNCB74 in Advanced Solid Tumors

for Ovarian Cancer

Sites in Boston +12 more locations

Sponsor: NextCure, Inc.

Sex: All·Age: 18+

Code: NCT06774963·Phase 1·Recruiting·Listed Jan 2025

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Study to Evaluate ACDN-01 in ABCA4-related Stargardt Retinopathy (STELLAR)

for Stargardt Disease

Sites in Boston +9 more locations

Sponsor: Ascidian Therapeutics, Inc

Sex: All·Age: 12+

Code: NCT06467344·Phase 1, Phase 2·Recruiting·Listed Jun 2024

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A Study of STM-416 Administered to Patients Undergoing TURBT for Recurrent Bladder Cancer

for Non-muscle-invasive Bladder Cancer

Sites in Boston +18 more locations

Sponsor: SURGE Therapeutics

Sex: All·Age: 18+

Code: NCT05710848·Phase 1, Phase 2·Recruiting·Listed Feb 2023

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A Master Protocol to Evaluate DCC-3009 in Gastrointestinal Stromal Tumor (GIST)

for Gastrointestinal Stromal Tumor (GIST)

Sites in Boston +9 more locations

Sponsor: Deciphera Pharmaceuticals, LLC

Sex: All·Age: 18+

Code: NCT06630234·Phase 1, Phase 2·Recruiting·Listed Oct 2024

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Minima Stent System Post- Approval Study (PAS)

for Pulmonary Artery Stenosis

Sites in Boston +14 more locations

Sponsor: Renata Medical

Sex: All·Age: All ages

Code: NCT06828770·Recruiting·Listed Feb 2025

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A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease

for Autoimmune Diseases

Sites in Waltham +10 more locations

Sponsor: TScan Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06587828·Recruiting·Listed Sep 2024

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First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer

for PIK3CA Mutation

Sites in Boston +22 more locations

Sponsor: Relay Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05216432·Phase 1·Recruiting·Listed Jan 2022

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A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

for Locally Advanced Solid Tumors

Drug: Repotrectinib

Sites in Boston +11 more locations

Sponsor: Turning Point Therapeutics, Inc.

Sex: All·Age: Up to 25

Code: NCT04094610·Phase 1, Phase 2·Recruiting·Listed Sep 2019

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Efficacy in Controlling Myopia in Young Children Using a Novel Spectacle Lens

for Myopia

Sites in Boston +13 more locations

Sponsor: SightGlass Vision, Inc.

Sex: All·Age: 6 - 8·Accepts healthy volunteers

Code: NCT06034327·Recruiting·Listed Sep 2023

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Safety and Effectiveness of Mechanical Thrombectomy Using the Anaconda ANA Funnel Catheter

for Acute Ischemic Stroke From Large Vessel Occlusion

Sites in Boston +10 more locations

Sponsor: Anaconda Biomed S.L.

Sex: All·Age: 22 - 85

Code: NCT06370182·Recruiting·Listed Apr 2024

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Extension Study to Evaluate Safety and Tolerability of Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)

for EPP

Sites in Boston, Brighton +13 more locations

Sponsor: Tanabe Pharma America, Inc.

Sex: All·Age: 12 - 75

Code: NCT05005975·Phase 3·Recruiting·Listed Aug 2021

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Eganelisib as Monotherapy and in Combination With Cytarabine in Relapsed/Refractory AML

for AML, Adult

Sites in Boston +10 more locations

Sponsor: Stelexis BioSciences

Sex: All·Age: 18+

Code: NCT06533761·Phase 1·Recruiting·Listed Aug 2024

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Phase 1b Study of OP-1250 (Palazestrant) in Combination With Ribociclib, Alpelisib, Everolimus, or Atirmociclib in ER+, HER2- Breast Cancer

for Metastatic Breast Cancer

Drug: Palazestrant

Sites in Boston +13 more locations

Sponsor: Olema Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT05508906·Phase 1·Recruiting·Listed Aug 2022

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AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma

for B-cell Malignancy

Sites in Worcester +12 more locations

Sponsor: Carna Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT05602363·Phase 1·Recruiting·Listed Nov 2022

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Medtronic Terminate AF Study

for Persistent Atrial Fibrillation

Sites in Boston +6 more locations

Sponsor: Medtronic Cardiac Surgery

Sex: All·Age: 18+

Code: NCT03546374·Recruiting·Listed Jun 2018

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NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

for Major Depressive Disorder

Drug: NBI-1065845

Sites in Boston +9 more locations

Sponsor: Neurocrine Biosciences

Sex: All·Age: 18+

Code: NCT06911112·Phase 3·Recruiting·Listed Apr 2025

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Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies

for Advanced Solid Tumor

Sites in Boston +9 more locations

Sponsor: Circle Pharma

Sex: All·Age: 12+

Code: NCT06577987·Phase 1·Recruiting·Listed Aug 2024

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Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

for Head and Neck Squamous Cell Carcinoma

Sites in Boston +14 more locations

Sponsor: Bicara Therapeutics

Sex: All·Age: 18+

Code: NCT04429542·Phase 1·Recruiting·Listed Jun 2020

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CERAMENT™| Bone Void Filler Device Registry

for Orthopedic Disorder

Sites in Boston +10 more locations

Sponsor: BONESUPPORT AB

Sex: All·Age: 18+

Code: NCT04244942·Recruiting·Listed Jan 2020

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A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)

for Locally Advanced Solid Tumor

Sites in Boston +18 more locations

Sponsor: Nuvalent Inc.

Sex: All·Age: 12+

Code: NCT05118789·Phase 1, Phase 2·Recruiting·Listed Nov 2021

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Study to Assess Safety and Tolerability of OPN-6602 in Subjects With Relapsed and/or Refractory Multiple Myeloma

for Relapsed Multiple Myeloma

Sites in Boston +11 more locations

Sponsor: Opna Bio LLC

Sex: All·Age: 18+

Code: NCT06433947·Phase 1·Recruiting·Listed May 2024

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A Study of RSLV-132 in Females With Sjögren's Disease

for Primary Sjögren Syndrome

Sites in Boston +23 more locations

Sponsor: Resolve Therapeutics

Sex: Female·Age: 18 - 75

Code: NCT06440525·Phase 2·Recruiting·Listed Jun 2024

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A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

for Advanced Solid Tumors

Sites in Boston +17 more locations

Sponsor: Marengo Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05592626·Phase 1, Phase 2·Recruiting·Listed Oct 2022

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Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

for Major Depressive Disorder

Drug: NBI-1065845

Sites in Boston +12 more locations

Sponsor: Neurocrine Biosciences

Sex: All·Age: 18+

Code: NCT06786624·Phase 3·Recruiting·Listed Jan 2025

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Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors

for Locally Advanced Solid Tumor

Sites in Boston +13 more locations

Sponsor: Tango Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05732831·Phase 1, Phase 2·Recruiting·Listed Feb 2023

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Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration

for Solid Tumors

Sites in Boston +16 more locations

Sponsor: ORIC Pharmaceuticals

Sex: All·Age: 18+

Code: NCT05315700·Phase 1, Phase 2·Recruiting·Listed Apr 2022

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(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

for Advanced Systemic Mastocytosis (AdvSM)

Sites in Boston +8 more locations

Sponsor: Cogent Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT04996875·Phase 2·Recruiting·Listed Aug 2021

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A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies

for Solid Tumor, Adult

Sites in Boston +12 more locations

Sponsor: GV20 Therapeutics

Sex: All·Age: 18+

Code: NCT05669430·Phase 1, Phase 2·Recruiting·Listed Dec 2022

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MB-105 in Patients With CD5 Positive T-cell Lymphoma

for Lymphoma, T-Cell

Sites in Boston +11 more locations

Sponsor: March Biosciences Inc

Sex: All·Age: 18+

Code: NCT06534060·Phase 2·Recruiting·Listed Aug 2024

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Desara ® One Single Incision Sling 522 Study

for Stress Urinary Incontinence

Sites in Cambridge +14 more locations

Sponsor: Caldera Medical, Inc.

Sex: Female·Age: 18+

Code: NCT04772131·Recruiting·Listed Feb 2021

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A Study to Find Out How Safe REGN5668 is and How Well it Works In Adult Women When Given With Either Cemiplimab, or Cemiplimab + Fianlimab, or Ubamatamab

for Ovarian Cancer

Drug: Cemiplimab

Sites in Boston +11 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: Female·Age: 18+

Code: NCT04590326·Phase 1, Phase 2·Recruiting·Listed Oct 2020

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A Multicenter Multinational Observational Study of Children With Hypochondroplasia

for Hypochondroplasia

Sites in Boston +15 more locations

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: Up to 15

Code: NCT06212947·Recruiting·Listed Jan 2024

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An Observational Study in Subjects to Follow the Progression of Stargardt Disease Type 1 (STGD1) Caused by Bi-Allelic Autosomal Recessive Mutations in the ABCA4 Gene

for Stargardt

Sites in Boston +13 more locations

Sponsor: Splice Bio

Sex: All·Age: 12 - 65

Code: NCT06435000·Recruiting·Listed May 2024

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Cardiac RADIoablation Versus Repeat Catheter Ablation: a Pivotal Randomized Clinical Trial Evaluating Safety and Efficacy for Patients With High-risk Refractory Ventricular Tachycardia (RADIATE-VT)

for Tachycardia, Ventricular

Sites in Boston +10 more locations

Sponsor: Varian, a Siemens Healthineers Company

Sex: All·Age: 18+

Code: NCT05765175·Recruiting·Listed Mar 2023

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US National OCS Liver Perfusion (OLP) Registry

for Liver Transplant

Sites in Boston, Burlington +20 more locations

Sponsor: TransMedics

Sex: All·Age: All ages

Code: NCT05940857·Recruiting·Listed Jul 2023

Apply to this trial