Paid Clinical Trials in Massachusetts

Massachusetts has 3,593 paid clinical trials enrolling now across cities including Boston, Worcester and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Massachusetts include Mass General Hospital, Dana-Farber and Brigham and Women's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 17, 2026.

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3,593 clinical trials

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PPDTM CorEvitasTM Obesity (OBR) Drug Effectiveness and Safety Registry

for Obesity

1 location in Waltham

Sponsor: CorEvitas

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07598981·Enrolling By Invitation

Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD

for Geographic Atrophy (GA)

27 locations incl. Gilbert

Sponsor: ONL Therapeutics

Sex: All·Age: 55+

Code: NCT06659445·Phase 2·Recruiting

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort C: Bevacizumab

for Acute Respiratory Distress Syndrome (ARDS)

Drug: Bevacizumab

40 locations incl. Birmingham

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06701656·Phase 2·Recruiting

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OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels

for Cardiac Failure

7 locations incl. Los Angeles

Sponsor: Inova Health Care Services

Sex: All·Age: 18 - 99

Code: NCT06939751·Recruiting

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ALXN2420 Versus Placebo in Combination With Somatostatin Analogs in Participants With Acromegaly

for Acromegaly

9 locations incl. Los Angeles

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: 18 - 80

Code: NCT07037420·Phase 2·Recruiting

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Balloon Inflation Time for Esophageal Strictures (BITES): A Randomized Multi-Center Study

for Esophageal Atresia With Tracheo-esophageal Fistula

2 locations incl. Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: Up to 18

Code: NCT07100379·Recruiting

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Longitudinal Real-world Clinical Outcomes Study on Symplicity Renal Denervation

for Hypertension

1 location in Boston

Sponsor: Medtronic Vascular

Sex: All·Age: 18+

Code: NCT07174622·Recruiting

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Clinical Trial of OMTX705 in Combination With Gemcitabine/Nab-Paclitaxel and Tislelizumab in Patients With Advanced/Metastatic Pancreatic Adenocarcinoma

for Pancreatic Adenocarcinoma Metastatic

1 location in Boston

Sponsor: Oncomatryx Biopharma S.L.

Sex: All·Age: 18+

Code: NCT07377045·Phase 1·Recruiting

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Outcomes Tracking in Unilateral Vocal Fold Paralysis (UVFP) and Atrophy After Medialization Laryngeal Surgery

for Unilateral Vocal Cord Paralysis

10 locations incl. La Jolla

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT07579364·Enrolling By Invitation

Extended-release Buprenorphine as a Novel Low-dose Induction Strategy

for Opioid Use Disorder

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT06441604·Phase 2·Recruiting

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Study of Oral Fluid Testing Approach

for Cannabis Use

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 18 - 30

Code: NCT06891235·Recruiting

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Microbial Cell-free Metagenomic Sequencing for Suspected Infections in Adult Immunocompromised Outpatients

for Infection

6 locations incl. San Francisco

Sponsor: Karius, Inc.

Sex: All·Age: 18+

Code: NCT07110636·Recruiting

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A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

for Non-Small Cell Lung Cancer

Drug: Divarasib

50 locations incl. Anchorage

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06793215·Phase 3·Recruiting

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Study to Evaluate the Efficacy and Safety of Oral Rilzabrutinib in Adults With Immune Thrombocytopenia (ITP) Who Failed First-line Treatment

for Immune Thrombocytopenia

9 locations incl. Clovis

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT07007962·Phase 3·Recruiting

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ALXN2350 in Adult Participants With BAG3-Associated Dilated Cardiomyopathy

for BAG3 Mutation Associated Dilated Cardiomyopathy

6 locations incl. Birmingham

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: 18 - 70

Code: NCT07218887·Phase 1, Phase 2·Recruiting

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Promoting Resilience Among Adolescents and Young Adults With Sickle Cell Disease

for Sickle Cell Disease

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 8 - 25

Code: NCT06555939·Recruiting

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Care in Multiple Sclerosis (MS)

for Multiple Sclerosis

6 locations incl. Birmingham

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT07011914·Recruiting

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A Study Evaluating the Real-World Experience of Givinostat in Patients With Duchenne Muscular Dystrophy

for Duchene Muscular Dystrophy

Drug: Givinostat

7 locations incl. Little Rock

Sponsor: ITF Therapeutics LLC

Sex: All·Age: 6+

Code: NCT07127978·Recruiting

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The Short Sleep Study

for Short Sleepers

4 locations incl. Miami

Sponsor: Danisco

Sex: All·Age: 20 - 50

Code: NCT07567560·Recruiting

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Cryocompression for CIPN

for Chemotherapy-induced Peripheral Neuropathy

1 location in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT07064798·Recruiting

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Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

for Heart Failure - NYHA II - IV

32 locations incl. Huntsville

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07069738·Recruiting

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Adapting Psychosocial Resiliency Intervention for Parents of Adolescents and Young Adults With Cancer

for Caregiving for Cancer

1 location in Boston

Sponsor: Zeba Ahmad, Ph.D.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07139769·Recruiting

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A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

for Ovarian Neoplasms

20 locations incl. Newport Beach

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07213791·Phase 1·Recruiting

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A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

for Ovarian Neoplasms

83 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07213804·Phase 3·Recruiting

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A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma

for Asthma

Drug: Brenipatide

17 locations incl. Tempe

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT07219173·Phase 2·Recruiting

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Phase 2b Study of RPT904 as Monotherapy in Participants With IgE-Mediated Food Allergy

for Ig-E Mediated Food Allergy

Drug: RPT904

17 locations incl. Little Rock

Sponsor: RAPT Therapeutics, Inc.

Sex: All·Age: 12 - 55

Code: NCT07220811·Phase 2·Recruiting

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Testing "Doula Link", a Multi-Component Intervention to Improve Perinatal Mental Health

for Perinatal Depression

1 location in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT07217561·Recruiting

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Evaluation of a Powered Ankle Prosthesis Capable of Bidirectional Control Via Neural Recording and Cutaneous Stimulation in Free-Space and Walking Tasks

for Amputation

1 location in Cambridge

Sponsor: Massachusetts Institute of Technology

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT07645729·Recruiting

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Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation

for Atrial Fibrillation (AF)

35 locations incl. Dothan

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07175428·Phase 2·Recruiting

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A Trial of Self-Adjusted Nitrous Versus Placebo During Office Vasectomy

for Vasectomy

1 location in Boston

Sponsor: Alexandra J. Berger Eberhardt, MD

Sex: Male·Age: 18 - 85

Code: NCT07245628·EARLY_Phase 1·Recruiting

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Pilot Study of "Bottarga" Supplementation: A Little-known, Sustainable "Blue" Food

for Prediabetes

1 location in Sommerville

Sponsor: Cambridge Health Alliance

Sex: All·Age: 18 - 60

Code: NCT06988462·Recruiting

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Mind-body Resilience Program for Cardiac Arrest Survivors and Their Caregivers: Recovering Together After Cardiac Arrest

for Emotional Distress

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07143357·Recruiting

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ARC-IM System to Manage Symptomatic Blood Pressure Instability Secondary to Chronic Spinal Cord Injury

for Spinal Cord Injuries

12 locations incl. Little Rock

Sponsor: ONWARD Medical, Inc.

Sex: All·Age: 18 - 75

Code: NCT07147296·Recruiting

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Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors

for Small Cell Lung Carcinoma

4 locations incl. Iowa City

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT07006727·Phase 1·Recruiting

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A Study of ASP2138 Given Before Surgery, Then Chemotherapy After Surgery, in People With Pancreatic Ductal Cancer

for Pancreatic Ductal Adenocarcinoma

3 locations incl. Boston

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT07024615·Phase 1·Recruiting

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Spironolactone to Improve Pregnancy-Associated Hypertension Trajectories

for Preeclampsia

3 locations incl. Boston

Sponsor: Massachusetts General Hospital

Sex: Female·Age: 18+

Code: NCT07041281·Phase 2·Recruiting

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A Study of Brenipatide in Participants With Alcohol Use Disorder

for Alcohol Use Disorder

Drug: Brenipatide

29 locations incl. Scottsdale

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT07219953·Phase 3·Recruiting

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Identifying and Addressing Barriers to Retention in the Cervical Cancer Treatment Cascade Among Women With HIV in South Africa: Part 2

for Cervical Cancer

2 locations incl. Boston

Sponsor: Boston University Charles River Campus

Sex: Female·Age: 18+

Code: NCT06182241·Not Yet Recruiting

Stress Dynamics and Familial Risk for Depression in Female Adolescents

for Major Depressive Disorder

1 location in Belmont

Sponsor: Mclean Hospital

Sex: Female·Age: 13 - 15·Accepts healthy volunteers

Code: NCT06816329·Recruiting

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Cognitive Rehabilitation for Refugees With Traumatic Brain Injury and Cognitive Impairment

for TBI (Traumatic Brain Injury)

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 65

Code: NCT06839079·Recruiting

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