Paid Clinical Trials in Massachusetts

Massachusetts has 3,586 paid clinical trials enrolling now across cities including Boston, Worcester and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Massachusetts include Mass General Hospital, Dana-Farber and Brigham and Women's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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3,586 clinical trials

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Efficacy of Tezepelumab in Peanut Oral Immunotherapy

for Peanut Allergy

10 locations incl. Little Rock

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 12 - 55

Code: NCT07015996·Phase 2·Not Yet Recruiting

Time Restricted Eating (TRE) in Bipolar Disorder

for Bipolar Disorder (BD)

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 65

Code: NCT07211217·Recruiting

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Digital Health Technologies for Progressive Supranuclear Palsy and Dementia With Lewy Bodies

for Progressive Supranuclear Palsy(PSP)

2 locations incl. Lutherville

Sponsor: BioSensics

Sex: All·Age: 40 - 89

Code: NCT07240805·Not Yet Recruiting

Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder

for Alcohol Use Disorder

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 65

Code: NCT07296094·Phase 2·Not Yet Recruiting

Teenthrive 2: Treatments for Improving Mood in Teens

for Depression in Adolescence

2 locations incl. Boston

Sponsor: Butler Hospital

Sex: All·Age: 12 - 18

Code: NCT07475845·Recruiting

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DAREON®-NEC-1: A Study in People With Advanced Extrapulmonary Neuroendocrine Cancer to Compare Obrixtamig Plus Carboplatin and Etoposide Treatment With Standard Chemotherapy

for Extrapulmonary Neuroendocrine Cancer

Drug: Obrixtamig

21 locations incl. Scottsdale

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07544654·Phase 3·Not Yet Recruiting

LEGACY: Lung Cancer Screening in Individuals With a Lung Cancer Family History-Protocol B

for Family History of Lung Cancer

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07600801·Not Yet Recruiting

Study of Zola-cel (BMS-986353), in Participants With Autoimmune Cytopenia (Breakfree-AiCE)

for Chronic Immune Thrombocytopenia

Drug: BMS-986353

3 locations incl. Boston

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT07603557·Phase 2·Not Yet Recruiting

Wearable Spine Assessment in Adults With and Without Low Back or Neck Pain

for Low Back Pain

1 location in Newton

Sponsor: Ashkan Vaziri

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07643207·Recruiting

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Statins to Prevent Cancer Associated Blood Clots

for Venous Thromboembolism

2 locations incl. Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT07303816·Phase 4·Recruiting

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Sparsentan for the Treatment of VEGF Signaling Pathway Inhibitor-Associated Proteinuria

for Proteinuric Renal Disease

Drug: Sparsentan

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT07224776·Phase 1·Not Yet Recruiting

Testing the Impact of Pre-visit Priming for Medications

for Deprescribing

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 65+

Code: NCT07281131·Enrolling By Invitation

A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications

for Parkinson's Disease

26 locations incl. Phoenix

Sponsor: Bayer

Sex: All·Age: 45 - 75

Code: NCT07330258·Recruiting

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A Pilot Trial of One-Day Accelerated TMS and D-cycloserine in Suicidal Patients With Borderline Personality Disorder

for Borderline Personality Disorder (BPD)

1 location in Belmont

Sponsor: Mclean Hospital

Sex: All·Age: 18+

Code: NCT07460947·Phase 1, Phase 2·Recruiting

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Determination 2 - Isatuximab, Iberdomide, Bortezomib and Dexamethasone Induction, Followed by Risk- and Response-Adapted Consolidation and Maintenance Therapy, in Transplant-Eligible Patients With Newly Diagnosed Multiple Myeloma

for Multiple Myeloma

Drug: Iberdomide

3 locations incl. Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18 - 75

Code: NCT07624513·Phase 3·Not Yet Recruiting

Adding Biotherapy or Placebo to Standard Treatment for Advanced Kidney Cancer

for Advanced Clear Cell Renal Cell Carcinoma

41 locations incl. Fayetteville

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT07383441·Phase 3·Recruiting

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A Study of Lirafugratinib in Non-CCA Solid Tumors With FGFR2 Fusion or Rearrangement

for FGFR2 Gene Fusion/Rearrangement

Drug: Lirafugratinib

7 locations incl. Phoenix

Sponsor: Elevar Therapeutics

Sex: All·Age: 18+

Code: NCT07359820·Phase 2·Recruiting

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GBPDC: Gut-Brain in PD Consortium Master Protocol

for Parkinson Disease (PD)

7 locations incl. Stanford

Sponsor: Duke University

Sex: All·Age: 21 - 80·Accepts healthy volunteers

Code: NCT07567794·Not Yet Recruiting

An Efficacy and Safety Study of Cenegermin Ophthalmic Solution Compared With Vehicle in the Treatment of PCED

for Persistent Corneal Epithelial Defect

18 locations incl. Huntington Beach

Sponsor: Dompé Farmaceutici S.p.A

Sex: All·Age: 18+

Code: NCT07519902·Phase 3·Recruiting

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A Trial to Evaluate the Safety and Tolerability of DV700P-RNA and DV701B1.1-RNA Immunization in Combination With Antiretroviral Analytical Treatment Interruption (ATI) in People Living With HIV for Elicitation of V3-glycan Antibodies

for HIV

4 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 60

Code: NCT07569029·Phase 1·Not Yet Recruiting

Effects of taVNS on Fibromyalgia Pain

for Fibromyalgia, Pain

1 location in Cambridge

Sponsor: Spaulding Rehabilitation Hospital

Sex: All·Age: 18+

Code: NCT06193317·Not Yet Recruiting

Impact of a Virtual Reality-based Mindfulness Program on Clinician Wellness

for Wellness, Psychological

1 location in Worcester

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06246539·Not Yet Recruiting

Prediction Augmented Screening Initiative

for Lung Cancer

4 locations incl. Bedford

Sponsor: VA Office of Research and Development

Sex: All·Age: 50 - 80

Code: NCT06538636·Not Yet Recruiting

Subconjunctival Humira for Boston Keratoprosthesis

for Penetrating Keratoplasty

1 location in Boston

Sponsor: Massachusetts Eye and Ear Infirmary

Sex: All·Age: 18+

Code: NCT06926478·Phase 1·Not Yet Recruiting

Comparing the Safety and Efficacy of Apixaban and Rivaroxaban

for Atrial Fibrillation

1 location in Boston

Sponsor: VA Office of Research and Development

Sex: All·Age: 65+

Code: NCT06953726·Phase 4·Not Yet Recruiting

A RCT of Spectacles With Aspherical Lenslets or 0.05% Atropine for Myopia Control

for Myopia

12 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 5 - 11

Code: NCT07095894·Phase 3·Recruiting

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A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

for Left Ventricular Systolic Dysfunction

Drug: Finerenone

22 locations incl. Aurora

Sponsor: Bayer

Sex: All·Age: Up to 18

Code: NCT07192952·Phase 3·Recruiting

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Large Language Model-Generated Messages to Improve Guideline-Directed Medical Therapy in Heart Failure

for Heart Failure

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 85

Code: NCT07337577·Not Yet Recruiting

Do Video Recordings of Multidisciplinary Clinics Improve Quality of Life for People With ALS and Their Caregivers?

for Amyotrophic Lateral Sclerosis (ALS)

7 locations incl. Scottsdale

Sponsor: Trustees of Dartmouth College

Sex: All·Age: 18+

Code: NCT07454733·Not Yet Recruiting

Readiness Outcomes Affecting Return to Sport 3.0

for ACL Reconstruction

1 location in Waltham

Sponsor: Boston Children's Hospital

Sex: All·Age: 8 - 25

Code: NCT07476430·Not Yet Recruiting

Extracorporeal Shockwave Therapy and Platelet-Rich Plasma for Midportion Achilles Tendinopathy

for Achilles Injuries Tendon

1 location in Cambridge

Sponsor: Spaulding Rehabilitation Hospital

Sex: All·Age: 18 - 65

Code: NCT07483320·Not Yet Recruiting

A Study of JZP3507 (ONC206) in Recurrent Grade 2 or 3 Meningioma

for Meningioma

Drug: JZP3507

5 locations incl. San Francisco

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07533942·Phase 2·Not Yet Recruiting

PET Imaging Study Using Evuzamitide to Detect Cardiac Amyloidosis in Patients With Inconclusive Nuclear Scans and Elevated TAD1 Levels

for Amyloidogenic Transthyretin (ATTR) Amyloidosis

3 locations incl. Boston

Sponsor: Lorena Saelices

Sex: All·Age: All ages

Code: NCT07538518·Not Yet Recruiting

Impact of a Produce Prescription Program and Nutrition Education Intervention on Cardiovascular Health in Youth

for Dyslipidemia

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 2 - 17

Code: NCT07545005·Not Yet Recruiting

Impact of Fluciclovine (18F) PET (Positron Emission Tomography) on the Management of Prostate Cancer Following Negative or Equivocal PSMA (Prostate-Specific Membrane Antigen) PET Imaging at the Time of Biochemical Recurrence

for Prostate Cancer

6 locations incl. San Diego

Sponsor: Blue Earth Diagnostics

Sex: Male·Age: 18+

Code: NCT07569926·Phase 4·Not Yet Recruiting

Combination Upper-Airway Electrical and Pharmacological Stimulation for Obstructive Sleep Apnea

for Obstructive Sleep Apnea

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 79

Code: NCT07577661·Phase 1, Phase 2·Not Yet Recruiting

HIPS Feasibility Randomized Controlled Trial

for Hip Pain Chronic

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07586397·Not Yet Recruiting

Transcutaneous Auricular Vagus Nerve Stimulation Treatment for Rosacea

for Rosacea

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT07600424·Not Yet Recruiting

PROspect Registry :Post Market Clinical Follow-up Study

for Breast Surgery

1 location in Boston

Sponsor: Stryker Endoscopy

Sex: All·Age: 18+

Code: NCT07631468·Not Yet Recruiting

PPD™ CorEvitas™ Psoriasis (PSO) Early Treatment Response Non-Interventional Study

for Psoriasis

2 locations incl. Waltham

Sponsor: CorEvitas

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07648602·Recruiting

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