A Long-term Follow-up Study in Patients Who Received BEAM-101for Hemoglobinopathy17 locations incl. BirminghamSponsor: Beam Therapeutics Inc.Sex: All·Age: 14 - 37Code: NCT07373639·RecruitingApply to this trial
LMN-201 for Prevention of C. Difficile Infection Recurrencefor Clostridioides Difficile Infection16 locations incl. EscondidoSponsor: Lumen Bioscience, Inc.Sex: All·Age: 18+Code: NCT05330182·Phase 2, Phase 3·RecruitingApply to this trial
A Gaucher Disease Gene Therapy Trial With FLT201for Gaucher Disease Type 116 locations incl. Los AngelesSponsor: Spur TherapeuticsSex: All·Age: 18+Code: NCT07223944·Phase 3·RecruitingApply to this trial
A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathyfor Symptomatic Genetic Dilated Cardiomyopathy23 locations incl. BirminghamSponsor: Kardigan, Inc.Sex: All·Age: 18+Code: NCT07210723·Phase 2, Phase 3·RecruitingApply to this trial
PUL-042 Treatment in Patients With Parainfluenza Virus (PIV), Human Metapneumovirus (hMPV) or Respiratory Syncytial Virus (RSV)for Hematologic Malignancies11 locations incl. DuarteSponsor: Pulmotect, Inc.Sex: All·Age: 18+Code: NCT06665100·Phase 2·RecruitingApply to this trial
RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosusfor Systemic Lupus Erythematosus21 locations incl. OrangeSponsor: Cabaletta BioSex: All·Age: 18 - 65Code: NCT06121297·Phase 1, Phase 2·RecruitingApply to this trial
A Study of JNJ-87189401 Combined With JNJ-78278343 for Advanced Prostate Cancerfor Prostatic Neoplasms11 locations incl. AuroraSponsor: Janssen Research & Development, LLCSex: Male·Age: 18+Code: NCT06095089·Phase 1·RecruitingApply to this trial
The Ailliance Post-Market Clinical Studyfor Spinal Deformity23 locations incl. TucsonSponsor: Medtronic Spinal and BiologicsSex: All·Age: 18+Code: NCT05856370·RecruitingApply to this trial
Dose-escalation and Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Participants With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)for Non-Hodgkin Lymphoma18 locations incl. GilbertSponsor: Imugene LimitedSex: All·Age: 18+Code: NCT03666000·Phase 1·RecruitingApply to this trial
Blue Light Cystoscopy With Cysview® Registryfor Bladder Cancer23 locations incl. BirminghamSponsor: PhotocureSex: All·Age: 18+Code: NCT02660645·RecruitingApply to this trial
A Study to Find Out Whether BI 765423 Has an Effect on Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF) With or Without Standard Treatmentfor Idiopathic Pulmonary FibrosisDrug: BI 76542315 locations incl. BirminghamSponsor: Boehringer IngelheimSex: All·Age: 40+Code: NCT07036523·Phase 2·RecruitingApply to this trial
Study to Evaluate Subcutaneous (SC) VGA039 in Patients With Von Willebrand Disease (VWD)for Von Willebrand Disease (VWD)11 locations incl. Little RockSponsor: Vega Therapeutics, IncSex: All·Age: 12 - 75Code: NCT07115004·Phase 3·RecruitingApply to this trial
A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis.for Candidemia23 locations incl. BirminghamSponsor: Basilea PharmaceuticaSex: All·Age: 18+Code: NCT05421858·Phase 3·RecruitingApply to this trial
A Study to Assess the Efficacy and Safety of Efgartigimod IV in Adult Participants With Primary Immune Thrombocytopeniafor Primary Immune Thrombocytopenia (ITP)18 locations incl. PhoenixSponsor: argenxSex: All·Age: 18+Code: NCT06544499·Phase 3·RecruitingApply to this trial
Study of Efficacy and Safety of Iptacopan in Participants With IC-MPGNfor IC-MPGNDrug: Iptacopan22 locations incl. Los AngelesSponsor: Novartis PharmaceuticalsSex: All·Age: 12 - 60Code: NCT05755386·Phase 3·RecruitingApply to this trial
IDP-023 as a Single Agent and in Combination With Antibody Therapies in Patients With Advanced Hematologic Cancersfor NHL12 locations incl. Los AngelesSponsor: Indapta Therapeutics, INC.Sex: All·Age: 18+Code: NCT06119685·Phase 1, Phase 2·RecruitingApply to this trial
A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary Fibrosisfor Familial Pulmonary FibrosisDrug: Nerandomilast13 locations incl. Los AngelesSponsor: Boehringer IngelheimSex: All·Age: 40+Code: NCT07201922·Phase 3·RecruitingApply to this trial
Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension Systemfor Pulmonary Arterial Hypertension12 locations incl. La JollaSponsor: Aria CV, IncSex: All·Age: 18+Code: NCT04555161·RecruitingApply to this trial
A Long-Term Follow-Up Observational Study to Evaluate Safety in Subjects Who Have Received a Gene-Modified Regulatory T Cell (Treg) Therapeuticfor Rheumatoid Arthritis (RA)10 locations incl. San FranciscoSponsor: Sonoma Biotherapeutics, Inc.Sex: All·Age: 18 - 71Code: NCT07123038·RecruitingApply to this trial
Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Severe Active GPA or MPAfor ANCA Associated Vasculitis (AAV)11 locations incl. AuroraSponsor: Novartis PharmaceuticalsSex: All·Age: 18 - 75Code: NCT06868290·Phase 2·RecruitingApply to this trial
Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Diffuse Cutaneous Systemic Sclerosisfor Scleroderma, Diffuse14 locations incl. Los AngelesSponsor: Novartis PharmaceuticalsSex: All·Age: 18 - 70Code: NCT06655896·Phase 2·RecruitingApply to this trial
Post Approval Study of Liposorber LA-15 System for the Treatment of Focal Segmental Glomerulosclerosis in Childrenfor Focal Segmental Glomerulosclerosis12 locations incl. Loma LindaSponsor: Kaneka Medical America LLCSex: All·Age: Up to 21Code: NCT02235857·RecruitingApply to this trial
Study Evaluating the Safety, Tolerability, and Efficacy of Xaluritamig in Combination With Androgen Receptor Pathway Inhibitors in Participants With Metastatic Hormone-sensitive Prostate Cancerfor Metastatic Hormone-sensitive Prostate Cancer (mHSPC)8 locations incl. San FranciscoSponsor: AmgenSex: Male·Age: 18+Code: NCT07140900·Phase 1·RecruitingApply to this trial
Renal Pelvic Denervation Pilot Trialfor Uncontrolled Hypertension5 locations incl. BirminghamSponsor: Verve Medical, IncSex: All·Age: 21 - 80Code: NCT07005050·RecruitingApply to this trial
First in Human Study of TORL-1-23 in Participants With Advanced Cancerfor Advanced Solid Tumor9 locations incl. FullertonSponsor: TORL Biotherapeutics, LLCSex: All·Age: 18+Code: NCT05103683·Phase 1·RecruitingApply to this trial
US National TOP Registryfor Lung Transplant7 locations incl. PhoenixSponsor: TransMedicsSex: All·Age: All agesCode: NCT06513091·RecruitingApply to this trial
Study of EN-374 Gene Therapy in Participants With X-Linked Chronic Granulomatous Diseasefor X-Linked Chronic Granulomatous Disease8 locations incl. Los AngelesSponsor: EnsomaSex: Male·Age: 3 Months+Code: NCT06876363·Phase 1, Phase 2·RecruitingApply to this trial
A Study of Participants with Β-Thalassemia Treated with Betibeglogene Autotemcelfor Beta-Thalassemia6 locations incl. OaklandSponsor: Genetix Biotherapeutics Inc.Sex: All·Age: All agesCode: NCT06271512·RecruitingApply to this trial
AAV Gene Therapy Clinical Study in Adult Classic PKU (PHEdom)for Phenylketonurias5 locations incl. OrangeSponsor: NGGT INC.Sex: All·Age: 18 - 55Code: NCT06332807·Phase 1, Phase 2·RecruitingApply to this trial
BAFFR-targeting CAR T Cells for Patients With Relapsed or Refractory B-NHLfor Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma6 locations incl. DuarteSponsor: PeproMene Bio, Inc.Sex: All·Age: 18+Code: NCT05370430·Phase 1·RecruitingApply to this trial
An Observational Extension Study for Adult Patients Treated in Study R5459-RT-1944 Who Receive a Kidney Transplantfor Chronic Kidney Disease (CKD)9 locations incl. Los AngelesSponsor: Regeneron PharmaceuticalsSex: All·Age: 18 - 70Code: NCT05106387·RecruitingApply to this trial
A Study to Investigate the Safety of DSP-3077 After a Unilateral Eye Injection in Male and Female Participants 18 Years of Age or Older With Retinitis Pigmentosafor Retinitis Pigmentosa2 locations incl. BostonSponsor: Sumitomo Pharma America, Inc.Sex: All·Age: 18+Code: NCT06891885·Phase 1, Phase 2·RecruitingApply to this trial
A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH)for Congenital Adrenal Hyperplasia8 locations incl. San FranciscoSponsor: Crinetics Pharmaceuticals Inc.Sex: All·Age: 1 - 17Code: NCT07159841·Phase 2, Phase 3·RecruitingApply to this trial
AB-3028, a Programmable Circuit T Cell Therapy in Patients With Castration Resistant Prostate Cancer (CRPC)for Metastatic Castration Resistant Prostate Cancer (mCRPC)9 locations incl. DuarteSponsor: Arsenal Biosciences, Inc.Sex: Male·Age: 18+Code: NCT07285694·Phase 1, Phase 2·RecruitingApply to this trial
A Study to Evaluate the Safety and Efficacy of OPB-101 in Platinum-resistant Ovarian Cancerfor Ovarian Cancer Recurrent4 locations incl. DetroitSponsor: Outpace Bio, Inc.Sex: Female·Age: 18+Code: NCT07030907·Phase 1·RecruitingApply to this trial
A proof-of Concept Study to Assess Safety and Tolerability of HM15421/GC1134A in Patients With Fabry Diseasefor Fabry Disesase6 locations incl. Los AngelesSponsor: GC Biopharma CorpSex: All·Age: 18+Code: NCT06858397·Phase 1, Phase 2·RecruitingApply to this trial
Study of SX-682 Plus Enzalutamide in Men With ARPI-Resistant Metastatic Castration Resistant Prostate Cancerfor Metastatic Castration-resistant Prostate Cancer6 locations incl. Los AngelesSponsor: Syntrix Biosystems, Inc.Sex: Male·Age: 18+Code: NCT06228053·Phase 2·RecruitingApply to this trial
Reducing Fluid Overload in Heart Failure Patients Using a Non-invasive, Renal Independent Systemfor Chronic Heart Failure8 locations incl. La JollaSponsor: AquaPass Medical Ltd.Sex: All·Age: 21 - 79Code: NCT06360380·RecruitingApply to this trial
BSB-1001 in Patients Undergoing HLA-Matched Allogenic Hematopoietic Stem Cell Transplant for AML, ALL or MDSfor AML, Adult Recurrent6 locations incl. DuarteSponsor: BlueSphere Bio, IncSex: All·Age: 18 - 70Code: NCT06704152·Phase 1, Phase 2·RecruitingApply to this trial
Phase 1 Study of GC1130A in Patients With Sanfilippo Syndrome Type A (MPS IIIA)for Sanfilippo Syndrome Type A2 locations incl. OaklandSponsor: GC Biopharma CorpSex: All·Age: 12 Months - 18Code: NCT06567769·Phase 1·RecruitingApply to this trial