Clinical Trials at University of Minnesota

As of August 2026, 268 paid clinical trials are recruiting at University of Minnesota, located at MINNEAPOLIS VA MEDICAL CENTER, ONE VETERANS DRIVE, MINNEAPOLIS, MN 55417, phone (612) 725-2230 in Minneapolis, Minnesota. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 27, 2026.

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269 clinical trials at University of Minnesota

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Study of Efficacy and Safety of Iptacopan in Participants With IC-MPGN

for IC-MPGN

Drug: Iptacopan

Sites in Minneapolis +21 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 60

Code: NCT05755386·Phase 3·Recruiting·Listed Mar 2023

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Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Diffuse Cutaneous Systemic Sclerosis

for Scleroderma, Diffuse

Sites in Minneapolis +13 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 70

Code: NCT06655896·Phase 2·Recruiting·Listed Oct 2024

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Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Severe Active GPA or MPA

for ANCA Associated Vasculitis (AAV)

Sites in Minneapolis, Rochester +9 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT06868290·Phase 2·Recruiting·Listed Mar 2025

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A Study to Assess the Efficacy and Safety of Efgartigimod IV in Adult Participants With Primary Immune Thrombocytopenia

for Primary Immune Thrombocytopenia (ITP)

Sites in Minneapolis +16 more locations

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT06544499·Phase 3·Recruiting·Listed Aug 2024

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Study to Evaluate Subcutaneous (SC) VGA039 in Patients With Von Willebrand Disease (VWD)

for Von Willebrand Disease (VWD)

Sites in Minneapolis +10 more locations

Sponsor: Vega Therapeutics, Inc

Sex: All·Age: 12 - 75

Code: NCT07115004·Phase 3·Recruiting·Listed Aug 2025

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A Long-Term Follow-Up Observational Study to Evaluate Safety in Subjects Who Have Received a Gene-Modified Regulatory T Cell (Treg) Therapeutic

for Rheumatoid Arthritis (RA)

Sites in Minneapolis +9 more locations

Sponsor: Sonoma Biotherapeutics, Inc.

Sex: All·Age: 18 - 71

Code: NCT07123038·Recruiting·Listed Aug 2025

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Dose-escalation and Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Participants With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)

for Non-Hodgkin Lymphoma

Sites in Minneapolis +9 more locations

Sponsor: Imugene Limited

Sex: All·Age: 18+

Code: NCT03666000·Phase 1·Recruiting·Listed Sep 2018

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Blue Light Cystoscopy With Cysview® Registry

for Bladder Cancer

Sites in Minneapolis +20 more locations

Sponsor: Photocure

Sex: All·Age: 18+

Code: NCT02660645·Recruiting·Listed Jan 2016

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Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System

for Pulmonary Arterial Hypertension

Sites in Minneapolis, Rochester +7 more locations

Sponsor: Aria CV, Inc

Sex: All·Age: 18+

Code: NCT04555161·Recruiting·Listed Sep 2020

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IDP-023 as a Single Agent and in Combination With Antibody Therapies in Patients With Advanced Hematologic Cancers

for NHL

Sites in Minneapolis +8 more locations

Sponsor: Indapta Therapeutics, INC.

Sex: All·Age: 18+

Code: NCT06119685·Phase 1, Phase 2·Recruiting·Listed Nov 2023

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Post Approval Study of Liposorber LA-15 System for the Treatment of Focal Segmental Glomerulosclerosis in Children

for Focal Segmental Glomerulosclerosis

Sites in Minneapolis +9 more locations

Sponsor: Kaneka Medical America LLC

Sex: All·Age: Up to 21

Code: NCT02235857·Recruiting·Listed Sep 2014

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EXACT Study: A Blinded Study in Patients With Alport Syndrome to Evaluate Exaluren Efficacy and Safety

for Alport Syndrome, X-Linked

Sites in Minneapolis +7 more locations

Sponsor: Eloxx Pharmaceuticals, Inc.

Sex: All·Age: 12+

Code: NCT07523581·Phase 2·Recruiting·Listed Apr 2026

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AB-3028, a Programmable Circuit T Cell Therapy in Patients With Castration Resistant Prostate Cancer (CRPC)

for Metastatic Castration Resistant Prostate Cancer (mCRPC)

Sites in Minneapolis +8 more locations

Sponsor: Arsenal Biosciences, Inc.

Sex: Male·Age: 18+

Code: NCT07285694·Phase 1, Phase 2·Recruiting·Listed Dec 2025

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Study Evaluating the Safety, Tolerability, and Efficacy of Xaluritamig in Combination With Androgen Receptor Pathway Inhibitors in Participants With Metastatic Hormone-sensitive Prostate Cancer

for Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

Sites in Minneapolis +7 more locations

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT07140900·Phase 1·Recruiting·Listed Aug 2025

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A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH)

for Congenital Adrenal Hyperplasia

Sites in Minneapolis +8 more locations

Sponsor: Crinetics Pharmaceuticals Inc.

Sex: All·Age: 1 - 17

Code: NCT07159841·Phase 2, Phase 3·Recruiting·Listed Sep 2025

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AAV Gene Therapy Clinical Study in Adult Classic PKU (PHEdom)

for Phenylketonurias

Sites in Minneapolis +4 more locations

Sponsor: NGGT INC.

Sex: All·Age: 18 - 55

Code: NCT06332807·Phase 1, Phase 2·Recruiting·Listed Mar 2024

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An Observational Extension Study for Adult Patients Treated in Study R5459-RT-1944 Who Receive a Kidney Transplant

for Chronic Kidney Disease (CKD)

Sites in Minneapolis +6 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18 - 70

Code: NCT05106387·Recruiting·Listed Nov 2021

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Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGN

for C3 Glomerulopathy

Drug: Iptacopan

Sites in Minneapolis +4 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 100

Code: NCT03955445·Phase 3·Recruiting·Listed May 2019

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ISP-001: Sleeping Beauty Transposon-Engineered B Cells for MPS I

for Mucopolysaccharidosis IH/S

Sites in Minneapolis +1 more location

Sponsor: Immusoft of CA, Inc.

Sex: All·Age: 10+

Code: NCT05682144·Phase 1·Recruiting·Listed Jan 2023

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Reducing Fluid Overload in Heart Failure Patients Using a Non-invasive, Renal Independent System

for Chronic Heart Failure

Sites in Minneapolis +7 more locations

Sponsor: AquaPass Medical Ltd.

Sex: All·Age: 21 - 79

Code: NCT06360380·Recruiting·Listed Apr 2024

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Study of SX-682 Plus Enzalutamide in Men With ARPI-Resistant Metastatic Castration Resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

Sites in Minneapolis +5 more locations

Sponsor: Syntrix Biosystems, Inc.

Sex: Male·Age: 18+

Code: NCT06228053·Phase 2·Recruiting·Listed Jan 2024

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A Study to Investigate the Safety of DSP-3077 After a Unilateral Eye Injection in Male and Female Participants 18 Years of Age or Older With Retinitis Pigmentosa

for Retinitis Pigmentosa

Sites in Minneapolis +1 more location

Sponsor: Sumitomo Pharma America, Inc.

Sex: All·Age: 18+

Code: NCT06891885·Phase 1, Phase 2·Recruiting·Listed Mar 2025

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Renal Pelvic Denervation Pilot Trial

for Uncontrolled Hypertension

Sites in Minneapolis, Rochester +3 more locations

Sponsor: Verve Medical, Inc

Sex: All·Age: 21 - 80

Code: NCT07005050·Recruiting·Listed Jun 2025

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First in Human Study of TORL-1-23 in Participants With Advanced Cancer

for Advanced Solid Tumor

Sites in Minneapolis, Rochester +7 more locations

Sponsor: TORL Biotherapeutics, LLC

Sex: All·Age: 18+

Code: NCT05103683·Phase 1·Recruiting·Listed Nov 2021

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A Study to Evaluate the Safety and Efficacy of OPB-101 in Platinum-resistant Ovarian Cancer

for Ovarian Cancer Recurrent

Sites in Minneapolis +3 more locations

Sponsor: Outpace Bio, Inc.

Sex: Female·Age: 18+

Code: NCT07030907·Phase 1·Recruiting·Listed Jun 2025

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BAFFR-targeting CAR T Cells for Patients With Relapsed or Refractory B-NHL

for Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma

Sites in Minneapolis +5 more locations

Sponsor: PeproMene Bio, Inc.

Sex: All·Age: 18+

Code: NCT05370430·Phase 1·Recruiting·Listed May 2022

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A proof-of Concept Study to Assess Safety and Tolerability of HM15421/GC1134A in Patients With Fabry Disease

for Fabry Disesase

Sites in Minneapolis +5 more locations

Sponsor: GC Biopharma Corp

Sex: All·Age: 18+

Code: NCT06858397·Phase 1, Phase 2·Recruiting·Listed Mar 2025

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BSB-1001 in Patients Undergoing HLA-Matched Allogenic Hematopoietic Stem Cell Transplant for AML, ALL or MDS

for AML, Adult Recurrent

Sites in Minneapolis +5 more locations

Sponsor: BlueSphere Bio, Inc

Sex: All·Age: 18 - 70

Code: NCT06704152·Phase 1, Phase 2·Recruiting·Listed Nov 2024

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Phase 1 Study of GC1130A in Patients With Sanfilippo Syndrome Type A (MPS IIIA)

for Sanfilippo Syndrome Type A

Sites in Minneapolis +1 more location

Sponsor: GC Biopharma Corp

Sex: All·Age: 12 Months - 18

Code: NCT06567769·Phase 1·Recruiting·Listed Aug 2024

Apply to this trial

US National TOP Registry

for Lung Transplant

Sites in Minneapolis +6 more locations

Sponsor: TransMedics

Sex: All·Age: All ages

Code: NCT06513091·Recruiting·Listed Jul 2024

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A Study of Participants with Β-Thalassemia Treated with Betibeglogene Autotemcel

for Beta-Thalassemia

Sites in Minneapolis +5 more locations

Sponsor: Genetix Biotherapeutics Inc.

Sex: All·Age: All ages

Code: NCT06271512·Recruiting·Listed Feb 2024

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Phase 1b/2a Randomized Double-blind Study to Investigate Safety Tolerability PK PD Preliminary Efficacy of Oral Administration of SNIPR001 in Patients With Hematologic Malignancy Scheduled for Allogeneic Hematopoietic Stem-Cell Transplant Receiving FQ Prophylaxis & Harboring FQR Ecoli Pre-Transplant

for E Coli Infections

Sites in Minneapolis +7 more locations

Sponsor: SNIPR Biome Aps.

Sex: All·Age: 18+

Code: NCT06938867·Phase 1, Phase 2·Recruiting·Listed Apr 2025

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Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)

for Hematologic Malignancy

Sites in Minneapolis +4 more locations

Sponsor: Tr1X, Inc.

Sex: All·Age: 18+

Code: NCT06462365·Phase 1·Recruiting·Listed Jun 2024

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Feasibility of a Remotely Delivered Step Count Intervention in Chronic Stroke

for Stroke

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07649135·Recruiting·Listed Jun 2026

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MRI as Noninvasive Innovative Approach in Detection and Monitoring of Malignant Oral Lesions in Fanconi Anemia Patients

for Fanconi Anemia

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07649031·Recruiting·Listed Jun 2026

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Fast-Her: Fasting Effects on Breast Cancer Treatment

for Metastatic Breast Cancer

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07624617·Recruiting·Listed Jun 2026

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Collaboration for Down Syndrome Progress (CDP)

for Down Syndrome

Sites in Minneapolis +15 more locations

Sponsor: RTI International

Sex: All·Age: All ages

Code: NCT07625579·Recruiting·Listed Jun 2026

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Elevated Rate Pacing of Cardiac Amyloidosis

for Cardiac Amyloidosis

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07583823·Recruiting·Listed May 2026

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Glucose and Activity Tracking for Sedentary Behavior Interventions in Older People With Type 2 Diabetes (TRACK T2D)

for Diabetes Mellitus, Type 2

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 55+

Code: NCT07524205·Recruiting·Listed Apr 2026

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Evaluating Noninvasive Brain Stimulation for TMD Pain: A Feasibility Study

for Temporomandibular Disorder

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 65

Code: NCT07517172·Recruiting·Listed Apr 2026

Apply to this trial