Clinical Trials at Vanderbilt University Medical Center

As of July 2026, 332 paid clinical trials are recruiting at Vanderbilt University Medical Center, located at Vanderbilt University Medical Center, 1211 Medical Center Dr, Nashville, TN 37232, phone (615) 322-5000 in Nashville, Tennessee. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 16, 2026.

Filter results

Filter results

State

City

Facility

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

332 clinical trials at Vanderbilt University Medical Center

·Clear filters·↓ Download CSV

Safety Study to Evaluate the Occurrence of EFAD in Pediatric Patients With PNAC Who Require More Than Eight Weeks of Omegaven Treatment

for Parenteral Nutrition Associated Liver Disease (PNALD)

10 locations incl. Fountain Valley

Sponsor: Fresenius Kabi

Sex: All·Age: 1 Day - 17

Code: NCT06274788·Recruiting

Apply to this trial

Validation of Donor-Derived Cell-Free DNA (Dd-cfDNA) for Kidney Transplant Monitoring

for Kidney Transplant Rejection

8 locations incl. Los Angeles

Sponsor: Insight Molecular Diagnostics

Sex: All·Age: 18+

Code: NCT07060716·Recruiting

Apply to this trial

ATTUNE: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION440 in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome (MDS)

for Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome

8 locations incl. San Diego

Sponsor: Ionis Pharmaceuticals, Inc.

Sex: Male·Age: 2 - 65

Code: NCT06430385·Phase 1, Phase 2·Recruiting

Apply to this trial

Multicenter Symphony IL-6 Monitoring Sepsis ICU Validation Study

for Sepsis, Septic Shock

5 locations incl. Gainesville

Sponsor: Bluejay Diagnostics, Inc.

Sex: All·Age: 22+

Code: NCT06654895·Recruiting

Apply to this trial

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

for Diffuse Astrocytoma, IDH-Mutant

6 locations incl. Beverly Hills

Sponsor: Neonc Technologies, Inc.

Sex: All·Age: 18+

Code: NCT06047379·Phase 1, Phase 2·Recruiting

Apply to this trial

A Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients With Refractory Advanced/Metastatic Colorectal Cancer

for Colorectal Cancer

9 locations incl. New Haven

Sponsor: Criterium, Inc.

Sex: All·Age: 18+

Code: NCT06992258·Phase 2·Recruiting

Apply to this trial

Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

for Ventricular Tachycardia (VT)

6 locations incl. Boston

Sponsor: Medtronic Cardiac Ablation Solutions

Sex: All·Age: 18 - 85

Code: NCT06703489·Recruiting

Apply to this trial

Clinical Outcome Measure at Stryker Spine

for Degenerative Disc Disease

7 locations incl. Jacksonville

Sponsor: VB Spine, LLC

Sex: All·Age: 18+

Code: NCT06226272·Recruiting

Apply to this trial

Use of CereGate Therapy for Freezing of Gait in PD

for Parkinson Disease

7 locations incl. Redwood City

Sponsor: CereGate Inc.

Sex: All·Age: 21 - 80

Code: NCT05292794·Recruiting

Apply to this trial

Saline Enhanced Radiofrequency (SERF) Needle Ablation for Refractory VT

for Refractory Ventricular Tachycardia

5 locations incl. Birmingham

Sponsor: Thermedical, Inc.

Sex: All·Age: 18+

Code: NCT05337241·Recruiting

Apply to this trial

Investigation of the Delve Detect Cerebrospinal Fluid (CSF) Metagenomic Next-generation Sequencing (mNGS) Test When Used for the Initial Diagnostic Workup of Patients With Suspected Central Nervous System (CNS) Infection

for Central Nervous System Infection

3 locations incl. San Francisco

Sponsor: Delve Bio, Inc.

Sex: All·Age: All ages

Code: NCT07435649·Recruiting

Apply to this trial

A Study of CSTI-500 in Patients With Prader-Willi Syndrome

for Prader-Willi Syndrome

1 location in Nashville

Sponsor: ConSynance Therapeutics

Sex: All·Age: 13 - 50

Code: NCT07348601·Phase 2·Recruiting

Apply to this trial

EEG Abnormalities in Adult ICU Patients With High Risk of Delirium

for Delirium in the Intensive Care Unit

1 location in Nashville

Sponsor: Ceribell Inc.

Sex: All·Age: 18+

Code: NCT07485244·Recruiting

Apply to this trial

Efficacy And Safety Evaluation of Glepaglutide in Treatment of SBS

for Short Bowel Syndrome

4 locations incl. St Louis

Sponsor: Zealand Pharma

Sex: All·Age: 18 - 90

Code: NCT07197944·Phase 3·Recruiting

Apply to this trial

A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures

for Focal Epilepsy

7 locations incl. Boise

Sponsor: Rapport Therapeutics Inc.

Sex: All·Age: 18 - 70

Code: NCT07219407·Phase 2·Recruiting

Apply to this trial

Registry Study for the Evaluation of High-risk Cardiac Patients by WILLEM AI-based ECG Platform

for High-risk Cardiac Patients

1 location in Nashville

Sponsor: Idoven 1903 S.L.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07333547·Recruiting

Apply to this trial

Substudy 03C: A Study of Combination Therapies in Participants With Renal Cell Carcinoma With Recurrent Disease During or After Anti-PD-(L)1 Therapy (MK-3475-03C/KEYMAKER-U03)

for Renal Cell Carcinoma

7 locations incl. San Francisco

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18 - 120

Code: NCT07049926·Phase 1, Phase 2·Recruiting

Apply to this trial

Early Feasibility Study (EFS) Laplace Transcatheter Tricuspid Valve Replacement (TTVR) System

for Tricuspid Regurgitation

6 locations incl. Tucson

Sponsor: Laplace Interventional, Inc

Sex: All·Age: 22 - 90

Code: NCT06183684·Recruiting

Apply to this trial

A First-in-human Study of KK8123 in Adults With X-linked Hypophosphatemia

for X-linked Hypophosphatemia

5 locations incl. San Francisco

Sponsor: Kyowa Kirin Co., Ltd.

Sex: All·Age: 18 - 65

Code: NCT06525636·Phase 1, Phase 2·Recruiting

Apply to this trial

Met Non Small Cell Cancer Registry (MOMENT)

for Cancer

3 locations incl. Fort Lauderdale

Sponsor: EMD Serono Research & Development Institute, Inc.

Sex: All·Age: All ages

Code: NCT05376891·Recruiting

Apply to this trial

Prospective Clinical Assessment Study in Children With Hypochondroplasia

for Hypochondroplasia

8 locations incl. Oakland

Sponsor: QED Therapeutics, a BridgeBio company

Sex: All·Age: 30 Months - 16

Code: NCT06410976·Recruiting

Apply to this trial

Otoferlin Gene-mediated Hearing Loss Natural History Study

for Sensorineural Hearing Loss, Bilateral

4 locations incl. Iowa City

Sponsor: Akouos, Inc.

Sex: All·Age: Up to 44

Code: NCT05572073·Recruiting

Apply to this trial

A Phase 2 Study of YA-101 in Patients With Multiple System Atrophy

for Multiple System Atrophy

6 locations incl. Los Angeles

Sponsor: Dasher Neuroscience Inc.

Sex: All·Age: 30+

Code: NCT06848231·Phase 2·Recruiting

Apply to this trial

Pounce™ Thrombectomy System Retrospective Registry

for Peripheral Arterial Disease

9 locations incl. Peoria

Sponsor: SurModics, Inc.

Sex: All·Age: 18+

Code: NCT05868161·Recruiting

Apply to this trial

Trisol System EFS Study

for Tricuspid Regurgitation

7 locations incl. Los Angeles

Sponsor: Trisol Medical

Sex: All·Age: 18+

Code: NCT04905017·Recruiting

Apply to this trial

The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry

for Cesarean Delivery

34 locations incl. Little Rock

Sponsor: Yale University

Sex: Female·Age: 15 - 55·Accepts healthy volunteers

Code: NCT06030063·Recruiting

Apply to this trial

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

for Cognitive Impairment, Mild

102 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 75+·Accepts healthy volunteers

Code: NCT04262206·Phase 4·Recruiting

Apply to this trial

HEALEY ALS Platform Trial - Master Protocol

for Amyotrophic Lateral Sclerosis

81 locations incl. Phoenix

Sponsor: Merit E. Cudkowicz, MD

Sex: All·Age: 18+

Code: NCT04297683·Phase 2, Phase 3·Recruiting

Apply to this trial

Fecal Microbiota Transplant National Registry

for Fecal Microbiota Transplantation

52 locations incl. Phoenix

Sponsor: American Gastroenterological Association

Sex: All·Age: All ages

Code: NCT03325855·Recruiting

Apply to this trial

Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)

for Optic Neuritis

33 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07100990·Phase 3·Recruiting

Apply to this trial

A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

for Cystic Fibrosis

68 locations incl. Birmingham

Sponsor: Nicole Hamblett

Sex: All·Age: 12+

Code: NCT06504589·Recruiting

Apply to this trial

Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

for Huntington's Disease

62 locations incl. Birmingham

Sponsor: CHDI Foundation, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT01574053·Recruiting

Apply to this trial

Gastroschisis Outcomes of Delivery (GOOD) Study

for Gastroschisis

38 locations incl. Phoenix

Sponsor: Medical College of Wisconsin

Sex: Female·Age: 18+

Code: NCT02774746·Recruiting

Apply to this trial

Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network

for Genetic Disease

33 locations incl. Birmingham

Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All·Age: 1 Month - 100·Accepts healthy volunteers

Code: NCT02450851·Recruiting

Apply to this trial

Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT

for Post Operative Surgical Site Infection

31 locations incl. Redwood City

Sponsor: Major Extremity Trauma Research Consortium

Sex: All·Age: 18 - 64

Code: NCT04678154·Phase 3·Recruiting

Apply to this trial

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

for Breast Neoplasms

42 locations incl. Birmingham

Sponsor: QuantumLeap Healthcare Collaborative

Sex: All·Age: 18+

Code: NCT01042379·Phase 2·Recruiting

Apply to this trial

Metastatic Ewing's Trial Testing Schedule Enhancement to Improve Outcomes

for Metastatic Ewing Sarcoma

17 locations incl. Birmingham

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 1+

Code: NCT07194044·Phase 1·Recruiting

Apply to this trial

A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue

for Pediatric Sarcoma, Refractory

22 locations incl. South Birmingham

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 2 - 40

Code: NCT05634369·Phase 1, Phase 2·Recruiting

Apply to this trial

Rapid Evacuation and Access of Cerebral Hemorrhage Trial

for Stroke Hemorrhagic

21 locations incl. Little Rock

Sponsor: Emory University

Sex: All·Age: 18 - 70

Code: NCT06870812·Recruiting

Apply to this trial

Heated Intraperitoneal Chemotherapy Followed by Niraparib for Ovarian, Primary Peritoneal and Fallopian Tube Cancer

for Stage III Ovarian Cancer

Drug: Niraparib

59 locations incl. Duarte

Sponsor: GOG Foundation

Sex: Female·Age: 18+

Code: NCT05659381·Phase 3·Recruiting

Apply to this trial