Paid Clinical Trials in North Carolina

North Carolina has 2,939 paid clinical trials enrolling now across cities including Durham, Chapel Hill and Winston-Salem. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in North Carolina include Duke University Medical Center, UNC Health and Wake Forest Baptist, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 17, 2026.

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2,944 clinical trials

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A Study to Test Whether Nerandomilast Helps People With Lungfibrosis Related to Rheumatic Diseases

for Interstitial Lung Diseases

Drug: Nerandomilast

33 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06806592·Phase 3·Recruiting

Apply to this trial

A Dose-masked Study of Intravitreal EYE103 in Participants With NVAMD or Macular Edema Following BRVO

for Neovascular Age-Related Macular Degeneration (NVAMD)

49 locations incl. Scottsdale

Sponsor: EyeBiotech Ltd.

Sex: All·Age: 18+

Code: NCT07205887·Phase 2·Recruiting

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A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

for Breast Neoplasms

46 locations incl. Hot Springs

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT06926868·Phase 2, Phase 3·Recruiting

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Bracing and Reconstruction of the Anterior Cruciate Ligament for Efficacy Trial

for Anterior Cruciate Ligament Injuries

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 14 - 39

Code: NCT06942754·Recruiting

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Once Daily Intrapleural Enzyme Therapy in Complicated Parapneumonic Effusion or Empyema

for Pleural Infection Bacterial

6 locations incl. New Haven

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18+

Code: NCT07095361·Phase 4·Recruiting

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Caring for the Carer

for Care Burden

1 location in Chapel Hill

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT07167641·Recruiting

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pH1N1 Blinded Challenge Study

for Influenza

2 locations incl. Baltimore

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07110532·Phase 1·Recruiting

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A Phase 2 Open-label Study to Evaluate the Safety of Laruparetigene Zovaparvovec Administered Bilaterally in Male Participants With X-Linked Retinitis Pigmentosa

for X-Linked Retinitis Pigmentosa (XLRP)

6 locations incl. Jacksonville

Sponsor: Beacon Therapeutics

Sex: Male·Age: 12 - 50

Code: NCT07174726·Phase 2·Recruiting

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Developing and Testing Drone-Delivered AEDs for Cardiac Arrests In Rural America

for Cardiac Arrest

1 location in Clemmons

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06229418·Recruiting

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Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

for Metastatic Clear Cell Renal Cell Carcinoma

Drug: Cabozantinib

40 locations incl. Gilbert

Sponsor: Arcus Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT07011719·Phase 3·Recruiting

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Education & Mentorship of Advanced Practice Providers to Increase Community-based Research Within the NCORP Network, COACH-APP Trial

for Other

31 locations incl. Newark

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06904391·Recruiting

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A Study to Evaluate the Safety and Efficacy of BGB-16673 Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

for Chronic Lymphocytic Leukemia

36 locations incl. Phoenix

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06973187·Phase 3·Recruiting

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A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases

for Refractory Autoimmune Diseases

2 locations incl. Boston

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT07115745·Phase 1·Recruiting

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Mobile Intervention for Suicidal Thoughts

for Suicide

1 location in Durham

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT06593379·Recruiting

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A Study of GNTI-122 in Adults Recently Diagnosed With T1D

for Type 1 Diabetes (T1D)

10 locations incl. Duarte

Sponsor: GentiBio, Inc

Sex: All·Age: 18 - 55

Code: NCT06919354·Phase 1·Recruiting

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Tenosynovial Giant Cell Tumor (TGCT) Real-World Participant Experience With Vimseltinib

for Tenosynovial Giant Cell Tumor

1 location in Wilmington

Sponsor: Deciphera Pharmaceuticals, LLC

Sex: All·Age: 18+

Code: NCT07075471·Recruiting

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Phase 2 Study of Inhaled SNG001 in Mechanically Ventilated Patients With Respiratory Viral Infection

for Viral Pneumonia

22 locations incl. Sacramento

Sponsor: Synairgen Research Ltd.

Sex: All·Age: 18+

Code: NCT06999603·Phase 2·Recruiting

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A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease

for Colorectal Cancer

22 locations incl. Huntsville

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07023289·Phase 2·Recruiting

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OPI-NXYDLD-303 Safety and Efficacy of Phentolamine Ophthalmic Solution in Keratorefractive Surgery Participants With Decreased Mesopic Visual Acuity

for Vision Loss Night

23 locations incl. Chandler

Sponsor: Ocuphire Pharma, Inc.

Sex: All·Age: 18+

Code: NCT07140783·Phase 3·Recruiting

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Provider Skill Building for Engagement and Communication in Healthcare - Hypertension Management

for Patient-centered Care

1 location in Durham

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT07147075·Enrolling By Invitation

Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)

for Elevated Lp(a)

Drug: Muvalaplin

121 locations incl. Gilbert

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07157774·Phase 3·Recruiting

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SNAPS Breast Cancer Patient Study Breast Cancer Patients

for Breast Cancer

1 location in Durham

Sponsor: Immunis.AI

Sex: Female·Age: 18+

Code: NCT05370300·Not Yet Recruiting

A Targeted Electronic Health Approach to Reduce Fear of Recurrence in Breast Cancer Survivors (FoRtitude)

for Breast Cancer Survivor

1 location in Chapel Hill

Sponsor: Eastern Cooperative Oncology Group

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT07122492·Not Yet Recruiting

Hospital-to-Home Transitional Care Interventions (H2H-TCI) Children/Youth With Special Health Care Needs (CYSHCN)

for Health Care

2 locations incl. Chapel Hill

Sponsor: Duke University

Sex: All·Age: Up to 18

Code: NCT06428175·Recruiting

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Bump the Lump - Intervention for the Treatment of Globus Pharyngeus

for Globus Pharyngeus

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06762444·Recruiting

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A Single-arm, Phase II Clinical Trial of ASPIRin to prEvent Venous Thromboembolism in Patients With Advanced Germ Cell Tumors Receiving Chemotherapy

for Germ Cell Tumor

3 locations incl. Charlotte

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18 - 70

Code: NCT06866964·Phase 2·Recruiting

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Long Term Follow-up Study for Subjects Administered CLBR001

for Long Term Follow-Up

3 locations incl. Indianapolis

Sponsor: Calibr, a division of Scripps Research

Sex: All·Age: 18+

Code: NCT06882317·Enrolling By Invitation

Clinical Evaluation of WaveLight Plus LASIK

for Myopia

1 location in Greensboro

Sponsor: Laser Defined Vision

Sex: All·Age: 18+

Code: NCT07127757·Recruiting

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An Open-Label Extension Study of Batoclimab in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

for Chronic Inflammatory Demyelinating Polyneuropathy

Drug: Batoclimab

5 locations incl. New Haven

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18+

Code: NCT07188844·Phase 2·Enrolling By Invitation

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

for Solid Tumor Malignancies

13 locations incl. Denver

Sponsor: Tasca Therapeutics

Sex: All·Age: 18+

Code: NCT07030257·Phase 1, Phase 2·Recruiting

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Optimizing Timing of Cesarean Delivery Consent on Labor and Delivery

for Pregnancy

1 location in Durham

Sponsor: Duke University

Sex: Female·Age: 18+

Code: NCT07117708·Recruiting

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A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

for Advanced Pancreatic Carcinoma

109 locations incl. Birmingham

Sponsor: Sameek Roychowdhury

Sex: All·Age: 18+

Code: NCT06906562·Phase 2·Recruiting

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A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Patients With Invasive Mold Infections.

for Invasive Mold Infections

18 locations incl. Birmingham

Sponsor: Basilea Pharmaceutica

Sex: All·Age: 18+

Code: NCT06925321·Phase 3·Recruiting

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Study to Evaluate Efficacy and Dose Response of Imapextide (STEADI)

for Postbariatric Hypoglycemia

4 locations incl. Aurora

Sponsor: MBX Biosciences

Sex: All·Age: 18 - 75

Code: NCT07029412·Phase 2·Recruiting

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Safety and Efficacy of ABP-745 in Participants With an Acute Gout Flare

for Acute Gouty Arthritis

14 locations incl. Peoria

Sponsor: Atom Therapeutics Co., Ltd

Sex: All·Age: 18 - 70

Code: NCT07145229·Phase 2·Recruiting

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855303-RNA Biomarker Validation

for Fractures, Bone

7 locations incl. Sacramento

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06872775·Enrolling By Invitation

An International Observational Study of Adults With Acute Infection

for Infectious Disease

19 locations incl. Tucson

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07069400·Recruiting

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Enhancing Resilience Among Patients With Stroke: Implementation of High Intensity Home-based Rehabilitation

for Stroke

1 location in Durham

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT07098286·Enrolling By Invitation

BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies

for Healthy

114 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 1 Day - 49·Accepts healthy volunteers

Code: NCT07160244·Phase 3·Recruiting

Apply to this trial

Telerehabilitation In The Home After Stroke

for Stroke

27 locations incl. Downey

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 80

Code: NCT06682429·Recruiting

Apply to this trial