Paid Clinical Trials in North Carolina

North Carolina has 2,939 paid clinical trials enrolling now across cities including Durham, Chapel Hill and Winston-Salem. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in North Carolina include Duke University Medical Center, UNC Health and Wake Forest Baptist, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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2,939 clinical trials

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Occlutech AFR Fontan Study

for Failure of Fontan Type Circulation

7 locations incl. Birmingham

Sponsor: Occlutech International AB

Sex: All·Age: All ages

Code: NCT07532369·Not Yet Recruiting

Reducing Post-Operative Opioid Prescribing in Southeastern North Carolina

for Opioid Prescribing

2 locations incl. Chapel Hill

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18+

Code: NCT07566182·Not Yet Recruiting

Trial Comparing the Safety and Efficacy of Two Different Oral VPV Doses With Placebo as Treatment for RV in Participants With COPD

for Rhinovirus Infection

14 locations incl. Tempe

Sponsor: Altesa Biosciences, Inc.

Sex: All·Age: 40 - 85

Code: NCT07610395·Phase 2·Recruiting

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Collaboration for Down Syndrome Progress (CDP)

for Down Syndrome

16 locations incl. Orange

Sponsor: RTI International

Sex: All·Age: All ages

Code: NCT07625579·Recruiting

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Evaluating the Efficacy of Platelet-rich Plasma Therapy in the Treatment of Androgenic Alopecia

for Androgenic Alopecia

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: Female·Age: 18+

Code: NCT03474718·EARLY_Phase 1·Not Yet Recruiting

BRiTE - Bispecific T Cell Engager for Patients With Glioblastoma

for Newly Diagnosed Glioblastoma

1 location in Durham

Sponsor: Mustafa Khasraw, MBChB, MD, FRCP, FRACP

Sex: All·Age: 18+

Code: NCT04903795·Phase 1·Not Yet Recruiting

Dental-Child Interaction Training

for Behavior and Behavior Mechanisms

4 locations incl. Fayetteville

Sponsor: University of Florida

Sex: All·Age: 18 - 99

Code: NCT06138405·Recruiting

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Utility of a Mobile Application for Young Women With Breast Cancer

for Breast Cancer

1 location in Charlotte

Sponsor: Wake Forest University Health Sciences

Sex: Female·Age: 18 - 45

Code: NCT07009093·Recruiting

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Horizon Two: HR NDMM (MMRC-100)

for High Risk Newly Diagnosed Multiple Myeloma

7 locations incl. Atlanta

Sponsor: Multiple Myeloma Research Consortium

Sex: All·Age: 18+

Code: NCT07053436·Phase 2·Recruiting

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Recovering Sleep After Trauma

for Post-traumatic Stress Disorder

1 location in Chapel Hill

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18 - 65

Code: NCT07196332·Recruiting

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Implementing a Group Physical Therapy Program for Veterans (GroupPT): Function QUERI 3.0

for Knee Osteoarthritis

1 location in Durham

Sponsor: VA Office of Research and Development

Sex: All·Age: All ages

Code: NCT07215572·Recruiting

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Implementing Cognitive Behavioral Therapy for Insomnia (SWELL): Function QUERI 3.0

for Chronic Insomnia

1 location in Durham

Sponsor: VA Office of Research and Development

Sex: All·Age: 60+

Code: NCT07216261·Recruiting

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Implementing a Mobile Health Application for Women Veterans With Urinary Incontinence (MyHealtheBladder): Function QUERI 3.0

for Urinary Incontinence

1 location in Durham

Sponsor: VA Office of Research and Development

Sex: Female·Age: All ages

Code: NCT07219433·Recruiting

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Assessment of Topical Minoxidil on Intraoperative Flap Perfusion and Cutaneous Flap Viability in Breast Recon

for Breast Reconstruction

1 location in Durham

Sponsor: Duke University

Sex: Female·Age: 18+

Code: NCT07264790·Phase 1·Recruiting

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Study of Oral Food Challenge Biomarkers (SAFER)

for Allergy

10 locations incl. Little Rock

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 12 Months - 17

Code: NCT07279467·Not Yet Recruiting

Studies of Insulin and Glucagon Action in the Liver

for Diabetes (DM)

1 location in Durham

Sponsor: Duke University

Sex: All·Age: 18 - 45·Accepts healthy volunteers

Code: NCT07300982·Phase 1, Phase 2·Not Yet Recruiting

Efficacy, Safety, and Tolerability of Zeleciment Basivarsen (DYNE-101) in Participants With Myotonic Dystrophy Type 1

for Myotonic Dystrophy Type 1 (DM1)

4 locations incl. Atlanta

Sponsor: Dyne Therapeutics

Sex: All·Age: 16+

Code: NCT07486934·Phase 3·Recruiting

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Comparison of Performance Using MED-EL Automatic Sound Management

for Hearing Loss, Sensorineural

1 location in Chapel Hill

Sponsor: Med-El Corporation

Sex: All·Age: 18+

Code: NCT07500311·Enrolling By Invitation

System Interventions to Achieve Early and Equitable Transplants Study - Long-Term

for Chronic Kidney Diseases

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18 - 75

Code: NCT07515794·Enrolling By Invitation

Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes

for Type 2 Diabetes Mellitus

15 locations incl. Santa Barbara

Sponsor: Insulet Corporation

Sex: All·Age: 18 - 75

Code: NCT07521475·Recruiting

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Mast Cell Treatment in Post-tick Bite Illness (PTBI)

for Post-tick Bite Illness

1 location in Chapel Hill

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 21 - 65·Accepts healthy volunteers

Code: NCT07526558·Phase 2·Not Yet Recruiting

GLOW Study: Effects of Triple Protein in Women

for Healthy Women

1 location in Chapel Hill

Sponsor: University of North Carolina, Chapel Hill

Sex: Female·Age: 30 - 60·Accepts healthy volunteers

Code: NCT07526571·Recruiting

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Comparing the Effects of Front-of-Package Labeling Schemes in Indonesia

for Nutrition

1 location in Chapel Hill

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07526584·Not Yet Recruiting

Observational Study of Adults and Adolescents With Erythropoietic Protoporphyria (EPP) and X-linked Porphyria (XLP)

for Erythropoietic Protoporphyria (EPP)

5 locations incl. Boston

Sponsor: Portal Therapeutics, Inc.

Sex: All·Age: 12+

Code: NCT07567131·Recruiting

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Descartes-08 in Autoantibody Myositis

for Antisynthetase Syndrome

2 locations incl. Chapel Hill

Sponsor: Cartesian Therapeutics

Sex: All·Age: 18+

Code: NCT07391605·Phase 2·Recruiting

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Tirzepatide in Obesity-Driven Endometrial Cancer

for Endometrial Cancer

Drug: Tirzepatide

1 location in Chapel Hill

Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: Female·Age: 18+

Code: NCT07065552·EARLY_Phase 1·Recruiting

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Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer

for Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

70 locations incl. Tucson

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07195734·Phase 2·Recruiting

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Pilot Study of Communication for Dual Users of Cigarettes and E-cigarettes

for Tobacco Products

1 location in Chapel Hill

Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07599462·Recruiting

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A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIV

for MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease

10 locations incl. Birmingham

Sponsor: Naga P. Chalasani

Sex: All·Age: 18+

Code: NCT07143968·Phase 2·Recruiting

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Integrated Health Care for PTSD

for Posttraumatic Stress Disorder (PTSD)

5 locations incl. Little Rock

Sponsor: Veterans Medical Research Foundation

Sex: All·Age: 18+

Code: NCT07220681·Recruiting

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Telehealth and Remote Blood Pressure

for Hypertension

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: Female·Age: 18 - 45

Code: NCT07356518·Recruiting

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PRESERVE: LUPKYNIS in Combination With Belimumab, Obinutuzumab or Anifrolumab in Patients With Lupus Nephritis

for Lupus Nephritis

15 locations incl. La Mesa

Sponsor: Aurinia Pharmaceuticals Inc.

Sex: All·Age: 18 - 75

Code: NCT07611214·Phase 4·Recruiting

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A Study of Ozanimod in Pregnant Women With Ulcerative Colitis and Their Offspring

for Ulcerative Colitis

1 location in Wilmington

Sponsor: Bristol-Myers Squibb

Sex: Female·Age: All ages

Code: NCT05953402·Recruiting

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A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease

for Crohn Disease

Drug: Risankizumab

17 locations incl. Dothan

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07499232·Phase 3·Recruiting

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AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss

for Obesity

Drug: NNC0487-0111

13 locations incl. Anniston

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07503210·Phase 3·Recruiting

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Addressing Barriers to Anti-hypertensive Medication Adherence Among PLWH Who Have Achieved Viral Suppression

for Hypertension

1 location in Durham

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT05459077·Not Yet Recruiting

A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE)

for Systemic Lupus Erythematosus

Drug: BI 3000202

31 locations incl. Beverly Hills

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18 - 74

Code: NCT07409181·Phase 2·Recruiting

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UNC Tobacco Convenience Store

for Health Behavior

1 location in Raleigh

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 21+

Code: NCT07458607·Recruiting

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Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015)

for Psoriatic Arthritis

Drug: Tulisokibart

15 locations incl. Sun City

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18 - 80

Code: NCT07486960·Phase 2·Recruiting

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AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

for Obesity

Drug: NNC0487-0111

19 locations incl. Escondido

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07509307·Phase 3·Recruiting

Apply to this trial