Methotrexate Clinical Trials in New York, NY
As of August 2026, 16 paid clinical trials are testing Methotrexate in New York, New York. Trials typically compensate participants for time, travel, and study visits, and many also provide study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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16 clinical trials testing Methotrexate
A Study of Gefitinib, Trametinib, Disulfiram, and Sunitinib in Addition to Standard Chemotherapy in People With Osteosarcoma
Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy
A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations
Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Primary CNS Lymphoma
Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia
Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia
A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy
A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)
Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder Arthroplasty
Cardiac Sarcoidosis Randomized Trial
TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II
Asparaginase Erwinia Chrysanthemi With Chemotherapy for the Treatment of High-Risk Adults With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma
Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies
Top Research Study Locations in New York
Researchers run research studies in New York, NY at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Memorial Sloan Kettering Cancer Center | Breast Cancer, Prostate Cancer, Endometrial Cancer | 461 |
| NYU Langone Health | Prostate Cancer, Lung Cancer, Major Depressive Disorder | 318 |
| Icahn School of Medicine at Mount Sinai | Crohn's Disease, Myelofibrosis, Prostate Cancer | 252 |
| Columbia University Irving Medical Center | Obesity, Insulin Resistance, Alzheimer Disease | 176 |
| Memorial Sloan Kettering Cancer Center (All Protocol Activities) | Breast Cancer, Multiple Myeloma, Lung Cancer | 155 |
| Weill Cornell Medicine | Depression, Heart Failure, Prostate Cancer | 139 |
| Mount Sinai Hospital | Heart Failure, Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8 | 121 |
| Columbia University Medical Center | Breast Cancer, Advanced Solid Tumor, Coronary Artery Disease | 119 |
| Columbia University | Amyotrophic Lateral Sclerosis, Obstetrical Complications, Colorectal Cancer | 110 |
| Hospital for Special Surgery | Systemic Lupus Erythematosus, Opioid Use, Rheumatoid Arthritis | 64 |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone | Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8 | 51 |
| Lenox Hill Hospital | Atrial Fibrillation, Anatomic Stage II Breast Cancer AJCC v8, Head and Neck Squamous Cell Carcinoma | 46 |
| Mount Sinai West | Anatomic Stage II Breast Cancer AJCC v8, Breast Cancer, Intracerebral Hemorrhage | 45 |
| Mount Sinai | Ovarian Cancer, AML, Advanced Solid Tumors | 44 |
| NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center | Malignant Solid Neoplasm, Acute Myeloid Leukemia, Neuroblastoma | 44 |
| Weill Cornell Medical College | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 43 |
| Memorial Sloan Kettering Cancer Center (All Protocol Activites) | Breast Cancer, Prostate Cancer, Pancreatic Cancer | 40 |
| NYP/Weill Cornell Medical Center | B Acute Lymphoblastic Leukemia, Malignant Solid Neoplasm, Anatomic Stage IV Breast Cancer AJCC v8 | 35 |
| New York University | Inflammatory Bowel Disease (IBD), Acute or Chronic Coronary Artery Disease, Adenine Phosphoribosyltransferase Deficiency | 29 |
| Memorial Sloan-Kettering Cancer Center | Advanced Solid Tumor, Breast Cancer, Colorectal Cancer (CRC) | 23 |
| Mount Sinai Chelsea | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | 22 |
| Manhattan Eye Ear and Throat Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8 | 21 |
| NYU Langone | Acute Gastrointestinal Bleeding, Advanced Breast Cancer, Advanced Cancer | 21 |
| Montefiore Medical Center | Mitral Regurgitation, Coronary Artery Disease, AML, Adult | 20 |
| The Mount Sinai Hospital | Homocystinuria, Intracerebral Hemorrhage, Ischemic Stroke | 18 |
Active & Upcoming Studies in New York (2026)
Recruiting trials in New York grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (1,132 active studies)
- Improving Affordability in Cancer Care Through Economic Screening and Support (I-ACCESS) · UNC Lineberger Comprehensive Cancer Center
- A Study to Evaluate Adverse Events and Change in Disease Activity With Injected Etentamig Plus Oral Pomalidomide Versus Standard Therapies in Adults With Relapsed or Refractory Multiple Myeloma · Phase 3 · AbbVie
Neurology & pain (198 active studies)
- Neuronavigation-guided FUS-induced BBB Opening in Alzheimer's Disease Patients and Its Effects on Brain Amyloid and Tau · Phase 1 · Columbia University
- Optimal Dosing of High-Intensity Locomotor Training for Step Attainment and Locomotor Outcomes in Stroke Patients Undergoing Acute Inpatient Rehabilitation · NYU Langone Health
Cardiovascular (195 active studies)
- Know Your Pressures NYC · Columbia University
- Optimizing Care For Management Of Hard To Control Hypertension In Low-Income Patients Across Family Health Centers In New York City · NYU Langone Health
Mental health & behavior (112 active studies)
- Whole-Body Hyperthermia for Mood and Anxiety Disorders · Weill Medical College of Cornell University
- Permanent Supportive Housing Overdose Prevention+ Study · NYU Langone Health
Diabetes & metabolic (106 active studies)
- South Asians With Type 2 Diabetes at Risk for Depression · NYU Langone Health
- Adaptive Dietary Intervention (ADI) for Asian Americans With Type 2 Diabetes · NYU Langone Health
HIV / STI (44 active studies)
- A Social Network Approach to Improve HIV Prevention and Substance Use Treatment For People Who Use Drugs · NYU Langone Health
- Expanding HOPE Liver · National Institute of Allergy and Infectious Diseases (NIAID)
Pediatric (34 active studies)
- Bilevel Positive Airway Pressure (BPAP) for Severe Asthma · Columbia University
- Neonatal Neurological Observation With Video AI · Artemis AI Labs
Vaccines (19 active studies)
- A Safety, Reactogenicity and Immunogenicity Trial of RVX-sCPD9 Booster Intranasal COVID-19 Vaccine · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- SARS-CoV-2 and Herpesvirus Inhibition for Ending Long COVID Dysfunction · Phase 2 · Icahn School of Medicine at Mount Sinai
Eye & vision (15 active studies)
- Know Your Pressures NYC · Columbia University
- TRYPTYR as a Treatment for Patients With Dry Eye Disease (DED) · Phase 4 · NYU Langone Health
Common conditions studied in New York
- Breast Cancer (92 active studies)
- Prostate Cancer (74 active studies)
- Multiple Myeloma (44 active studies)
- Colorectal Cancer (42 active studies)
- Ovarian Cancer (41 active studies)
- Endometrial Cancer (37 active studies)
Leading research sponsors in New York
- Memorial Sloan Kettering Cancer Center
- NYU Langone Health
- Columbia University
- Icahn School of Medicine at Mount Sinai
- Weill Medical College of Cornell University
Frequently asked questions
How many paid clinical trials are currently recruiting in New York?
There are approximately 3,383 recruiting clinical trials in New York, New York listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in New York pay participants?
Most recruiting trials in New York compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in New York?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in New York?
The most common conditions under active study in New York include Breast Cancer (92), Prostate Cancer (74), Multiple Myeloma (44), Colorectal Cancer (42), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in New York?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in New York on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in New York?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in New York?
Recruiting research sites in New York include Memorial Sloan Kettering Cancer Center, NYU Langone Health, Icahn School of Medicine at Mount Sinai, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in New York right now?
The largest active categories in New York are Cancer & tumors (1,132), Neurology & pain (198), Cardiovascular (195). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.