Paid Clinical Trials in Buffalo, NY
As of September 2026, 417 paid clinical trials are recruiting in Buffalo, New York. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Buffalo offers studies at sites including Roswell Park Cancer Institute for conditions such as Acute Myeloid Leukemia, Breast Cancer, Malignant Solid Neoplasm, Coronary Artery Disease. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Buffalo
Trials by drug in Buffalo
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Newly added in Buffalo
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Senior Center Medication Safety and Empowerment Curriculum
A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
Pediatric Food is Medicine Study
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.
380 clinical trials
A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)
A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)
Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease
A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial
Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML
Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors
Assessment of CCM in HF With Higher Ejection Fraction
A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)
Drug-Eluting Registry: Real-World Treatment of Lesions in the Peripheral Vasculature
A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel
ELEVATE High-Risk PCI Pivotal Study
ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve
RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™
A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies
Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma
Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)
Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.
A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)
A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes
A Study of ASP3082 in Adults With Advanced Solid Tumors
CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)
LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study
VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]
Top Research Study Locations in Buffalo
Researchers run research studies in Buffalo, NY at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Roswell Park Cancer Institute | Acute Myeloid Leukemia, Malignant Solid Neoplasm, Stage II Lung Cancer AJCC v8 | 149 |
| Roswell Park Comprehensive Cancer Center | Acute Myeloid Leukemia, Leukemia, Myeloid, Acute, Non-Hodgkin Lymphoma | 49 |
| University at Buffalo | Cardiovascular Diseases, Acute Abstinence From Cigarettes vs E-cigarettes (ENDS), Acute Ischemic Stroke | 21 |
| Buffalo General Medical Center | Acute Ischemic Stroke, Aortic Insufficiency, Aortic Regurgitation | 9 |
| State University of New York at Buffalo | Acute Ischemic Stroke, Acute Myeloid Leukemia (AML), Birth-weight-for-gestational-age z Score | 9 |
| University of Buffalo | Aortic Valve Insufficiency, Aortic Valve Stenosis, Carotid Artery Calcification | 6 |
| Roswell Park | Glioma, MAPK Pathway Gene Mutation, MEK Mutation | 5 |
| UBMD Pediatrics | Idiopathic Short Stature, Obesity, Diabetes Mellitus, Type 2 | 5 |
| University at Buffalo Neurosurgery | Cerebral Aneurysms, Clinical Need for Cranioplasty, Clinical Need for Craniotomy or Craniectomy | 4 |
| VA Western New York Healthcare System, Buffalo, NY | Alcohol-Related Disorders, Brain Concussion, Comorbid Post-Traumatic Stress Disorder and OCD | 4 |
| Erie County Medical Center | Anastomosis, Surgical, Free Tissue Transfer, Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands | 3 |
| Jacobs Institute | Aneurysm, Leak, Cerebrospinal Fluid, Moyamoya Disease | 3 |
| Oishei Children's Hospital | Bronchiolitis Acute, Children, Only, Failed or Difficult Intubation, Sequela | 3 |
| Rochester Clinical Research - Buffalo | Obesity, Atherosclerosis, Cardiovascular Disease | 3 |
| University of Buffalo Neurosurgery | ALS, ALS (Amyotrophic Lateral Sclerosis), ALS - Amyotrophic Lateral Sclerosis | 3 |
| University at Buffalo / Great Lakes Cancer Care | Integrative Oncology, Medical Nutrition Therapy, Medical Oncology | 2 |
| Akero Clinical Study Site | MASH - Metabolic Dysfunction-Associated Steatohepatitis, MASH With Fibrosis, NASH - Nonalcoholic Steatohepatitis | 2 |
| Buffalo General | Diastolic Heart Failure, Heart Failure, Heart Failure With Mid Range Ejection Fraction | 2 |
| Circuit Clinical | Hematologic Malignancies, Solid Tumors, Type 1 Diabetes | 2 |
| Dent Neurological Institute | Alzheimer Disease, Dementia, Generalized Myasthenia Gravis | 2 |
| Division of Behavioral Medicine Department of Pediatrics Jacobs School of Medicine and Biomedical Sciences State University of New York at Buffalo | Breastfeeding, Childhood Obesity, Pregnancy | 2 |
| Golisano Children's Hospital of Buffalo | Infant Safe Sleep Practices, Infant, Extremely Premature, Intensive Care Units, Neonatal | 2 |
| Research Foundation SUNY Buffalo | Aortoiliac Occlusive Disease, PFO - Patent Foramen Ovale, Stroke | 2 |
| Ross Eye Institute, University of Buffalo, Med School Dept Ophthalmology | Amblyopia | 2 |
| Sisters of Charity Hospital | Death; Neonatal, Intubation Complication, Percutaneous Coronary Intervention | 2 |
Active & Upcoming Studies in Buffalo (2026)
Recruiting trials in Buffalo grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (190 active studies)
- Testing an Experimental Approach to Treat Patients With Plasma Cell Leukemia, The QUANTUM Trial · Phase 2 · National Cancer Institute (NCI)
- Comparing Different Treatment Lengths for Venetoclax in Older People With Newly Diagnosed Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial) · Phase 2 · National Cancer Institute (NCI)
Neurology & pain (26 active studies)
- Infant Safe Sleep in Pediatric Emergency Depratment · State University of New York at Buffalo
- OsseoFit Stemless Shoulder System (Anatomic) · Zimmer Biomet
Diabetes & metabolic (23 active studies)
- Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS) · Phase 3 · Eli Lilly and Company
- A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event · Phase 2 · Eli Lilly and Company
Cardiovascular (23 active studies)
- A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event · Phase 2 · Eli Lilly and Company
- A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF · Phase 3 · AstraZeneca
Pediatric (15 active studies)
- Infant Safe Sleep in Pediatric Emergency Depratment · State University of New York at Buffalo
- Pediatric Food is Medicine Study · State University of New York at Buffalo
Mental health & behavior (13 active studies)
- Understanding Tobacco and Cannabis Co-Use Practices: Initiation, Escalation, and Maintenance · Roswell Park Cancer Institute
- Influence of Authorized Smokeless Tobacco Product Modified Risk Claims II: Laboratory Assessment of Sensory and Subjective Effects · Roswell Park Cancer Institute
Eye & vision (3 active studies)
- Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial · University of Pennsylvania
- Comparison of Intraocular Pressure Measurement With the Novel TonoVera Device With Other Commonly Used Devices · State University of New York at Buffalo
Vaccines (2 active studies)
- EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease · Phase 3 · Pfizer
- SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry · Massive Bio, Inc.
HIV / STI (2 active studies)
- Examining Migration, Social Bonds, Transnationalism, and HIV Prevention Pathways Among African Immigrants. · State University of New York at Buffalo
- Blood Collection Biorepository for Liver Disease Research · State University of New York at Buffalo
Common conditions studied in Buffalo
- Acute Myeloid Leukemia (13 active studies)
- Breast Cancer (7 active studies)
- Malignant Solid Neoplasm (7 active studies)
- Coronary Artery Disease (6 active studies)
- Endometrial Cancer (6 active studies)
- Obesity (6 active studies)
Leading research sponsors in Buffalo
- Roswell Park Cancer Institute
- State University of New York at Buffalo
- National Cancer Institute (NCI)
- Children's Oncology Group
- Alliance for Clinical Trials in Oncology
Frequently asked questions
How many paid clinical trials are currently recruiting in Buffalo?
There are approximately 417 recruiting clinical trials in Buffalo, New York listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Buffalo pay participants?
Most recruiting trials in Buffalo compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Buffalo?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Buffalo?
The most common conditions under active study in Buffalo include Acute Myeloid Leukemia (13), Breast Cancer (7), Malignant Solid Neoplasm (7), Coronary Artery Disease (6), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Buffalo?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Buffalo on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Buffalo?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Buffalo?
Recruiting research sites in Buffalo include Roswell Park Cancer Institute, Roswell Park Comprehensive Cancer Center, University at Buffalo, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Buffalo right now?
The largest active categories in Buffalo are Cancer & tumors (190), Neurology & pain (26), Diabetes & metabolic (23). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.