Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,650 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 8, 2026.

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3,650 clinical trials

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A Study to Evaluate Atumelnant in Adults With Congenital Adrenal Hyperplasia

for Congenital Adrenal Hyperplasia

9 locations incl. Los Angeles

Sponsor: Crinetics Pharmaceuticals Inc.

Sex: All·Age: 18 - 74

Code: NCT07144163·Phase 3·Recruiting

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The Erector Spinae Plane Block For Gastrointestinal Malignancy Pain Treatment (EGIPT)

for Gastrointestinal Malignancy

4 locations incl. Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT07211386·Recruiting

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Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Pancreatic Ductal Adenocarcinoma (PDAC)

for Pancreatic Ductal Adenocarcinoma (PDAC)

14 locations incl. Cerritos

Sponsor: SOFIE

Sex: All·Age: 18+

Code: NCT07217717·Phase 3·Recruiting

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From Screening to Support: A Multi-Method Analysis of HRSN Integration in Cancer Care

for Cancer

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07352579·Recruiting

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Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans

for Osteoarthritis, Knee

5 locations incl. Birmingham

Sponsor: VA Office of Research and Development

Sex: All·Age: 40 - 90

Code: NCT06488144·Phase 3·Recruiting

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A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

for Major Depressive Disorder (MDD)

32 locations incl. Birmingham

Sponsor: Cybin IRL Limited

Sex: All·Age: 18 - 85

Code: NCT06793397·Phase 3·Recruiting

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Neurophysiology of the Basal Ganglia, Thalamus, and Cerebellum in Patients With Movement Disorders

for Movement Disorders

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06848530·Recruiting

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Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of Care

for Glioblastoma

5 locations incl. Scottsdale

Sponsor: GT Medical Technologies, Inc.

Sex: All·Age: 18+

Code: NCT07195591·Phase 3·Recruiting

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A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older

for Clostridioides Difficile Associated Disease

135 locations incl. Athens

Sponsor: Pfizer

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT07282665·Phase 3·Recruiting

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Prevention of Recurrent C. Difficile Infection Study With AZD5148 Monoclonal Antibody

for Clostridioides Difficile Infection

42 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07285213·Phase 2·Recruiting

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A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults

for Psoriatic Arthritis

Drug: Bimekizumab

28 locations incl. Peoria

Sponsor: UCB Biopharma SRL

Sex: All·Age: 18+

Code: NCT07290036·Phase 1·Recruiting

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A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)

for Chronic Kidney Disease

Drug: Empagliflozin

30 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 2 - 17

Code: NCT07107945·Phase 3·Recruiting

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How the Method of Bladder Emptying After Epidural Placement in Labor Affects Postpartum Voiding

for Urinary Retention

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT07125326·Recruiting

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Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

for Ovarian Cancer

Drug: INCB123667

29 locations incl. Anchorage

Sponsor: Incyte Corporation

Sex: Female·Age: 18+

Code: NCT07214779·Phase 3·Recruiting

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Target Trial Emulation for Pharmacologic Treatment of Neonatal Opioid Withdrawal Syndrome

for Neonatal Opioid Withdrawal Syndrome

22 locations incl. Birmingham

Sponsor: HELP for NOWS Consortium

Sex: All·Age: 0 Minutes+

Code: NCT07278375·Recruiting

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Kaempferol Absorption and Pharmacokinetics Evaluation

for No Disease

3 locations incl. New York

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT07322406·Recruiting

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Efficacy and Safety of a Single Dose of LS301-IT for Fluorescence Intraoperative Molecular Imaging (IMI) for Patients Undergoing Lung Cancer Resection for Non Small Cell Lung Cancer

for Non Small Cell Lung Cancer (NSCLC)

2 locations incl. Philadelphia

Sponsor: Integro Theranostics

Sex: All·Age: 18+

Code: NCT07276789·Phase 2·Recruiting

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Evaluating the Implementation and Impact of an Enhanced SNAP-Ed Delivered Curriculum in Low-income Preschools

for Vegetable Acceptance in Early Childhood

1 location in Altoona

Sponsor: Penn State University

Sex: All·Age: 3+·Accepts healthy volunteers

Code: NCT07366437·Enrolling By Invitation

Study on Home Obstructive Respiratory Exacerbations

for COPD Exacerbation

1 location in Philadelphia

Sponsor: Strados Labs, Inc.

Sex: All·Age: 40 - 80

Code: NCT06544928·Enrolling By Invitation

Evaluating Artificial Intelligence-Based Clinical Decision Support for Sepsis and ARDS

for Sepsis

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07025096·Enrolling By Invitation

A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to Severe Rheumatoid Arthritis Who Have Not Responded to or Who Cannot Tolerate Tumor Necrosis Factor (TNF) and/or Janus Kinase (JAK Inhibitors)

for Rheumatoid Arthritis

Drug: RO7790121

12 locations incl. Peoria

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07137598·Phase 2·Recruiting

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A Study to Assess the Safety, Tolerability, Pharmacokinetic, Pharmacodynamic, Immunogenicity and Antitumour Activity of IPN60300 in Adults With Locally Advanced or Metastatic Solid Tumours

for Locally Advanced Solid Tumor

6 locations incl. New Haven

Sponsor: Ipsen

Sex: All·Age: 18+

Code: NCT07213817·Phase 1, Phase 2·Recruiting

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Evaluating the Effectiveness of the Health App Recommendation Tool

for Alzheimers Disease Related Dementias

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07216716·Recruiting

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A Phase IIb Study to Evaluate the Effect of Dapagliflozin in Combination With Baxdrostat Compared With Baxdrostat on Albuminuria in Participants With Chronic Kidney Disease and High Blood Pressure.

for Chronic Kidney Disease and Hypertension

Drug: Dapagliflozin

18 locations incl. Surprise

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07222917·Phase 2·Recruiting

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Artificial Intelligence Diagnostic Decision Support to Reduce Antimicrobial Prescriptions in Young Children With Colds

for Acute Otitis Media (AOM)

2 locations incl. Pittsburgh

Sponsor: Timothy Shope

Sex: All·Age: 6 Months - 24 Months

Code: NCT06876259·Recruiting

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Community Discussions and Social Participation

for Social Connectedness

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07013357·Enrolling By Invitation

A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02)

for Biliary Tract Cancer

Drug: Rilvegostomig

33 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07221253·Phase 3·Recruiting

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ESG in Obese Adolescents

for Obese Adolescents

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 12 - 17

Code: NCT06914765·Enrolling By Invitation

A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis

for Plaque Psoriasis

Drug: Deucravacitinib

42 locations incl. Birmingham

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 12 - 17

Code: NCT06979453·Phase 3·Recruiting

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Different Approaches for CART-EGFR-IL13Ra2 Dosing in Recurrent GBM

for Recurrent Glioblastoma

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07209241·Phase 1·Recruiting

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Effect of Donor Diabetes and Other Factors on Corneal Transplant Endothelial Cell Loss and Success at 5 Years

for Fuchs Endothelial Corneal Dystrophy

14 locations incl. Atlanta

Sponsor: Case Western Reserve University

Sex: All·Age: 30 - 93

Code: NCT07217249·Enrolling By Invitation

A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy

for Gastrointestinal Neoplasms

35 locations incl. Phoenix

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT07218926·Phase 3·Recruiting

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Dose Ranging Study of ORKA-001 in Patients With Moderate-to-Severe Plaque Psoriasis

for Plaque Psoriasis

20 locations incl. Phoenix

Sponsor: Oruka Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07290569·Phase 2·Recruiting

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A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitean-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

for Locally Advanced Urothelial Carcinoma

148 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06524544·Phase 3·Recruiting

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Impact of Circadian Rhythm on Immunotherapy

for Advanced/Metastatic NSCLC

1 location in Pittsburgh

Sponsor: Liza Villaruz, MD

Sex: All·Age: 18+

Code: NCT07224971·Phase 2·Recruiting

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A Study of DII235 in Adults With Elevated Lipoprotein(a)

for Lipoprotein Disorder

38 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 80

Code: NCT07235046·Phase 2·Recruiting

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Patient Navigation Program to Improve Clinical Trial Enrollment in Cancer Patients

for Prostate Cancer

2 locations incl. Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT06138067·Recruiting

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Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

for Castration-Sensitive Prostate Carcinoma

Drug: Apalutamide

194 locations incl. Tucson

Sponsor: Alliance for Clinical Trials in Oncology

Sex: Male·Age: 18+

Code: NCT06931340·Phase 3·Recruiting

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Allergy Delabeling in Antibiotic Stewardship - Evaluations

for Beta Lactam Allergy in Patients With a Hematologic Malignancy

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT06967467·Enrolling By Invitation

Preoperative Opioid Tapering Before Spine Surgery

for Opioid Consumption, Postoperative

1 location in Philadephia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07221786·Recruiting

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