Intracept Minimally-invasive PROcedure for VErtebrogenic Back Pain
for Chronic Low-back Pain
Sites in Pittsburgh +18 more locations
Sponsor: Boston Scientific Corporation
Sex: All·Age: 18+
Code: NCT06827262·Recruiting·Listed Feb 2025
Paid Clinical Trials in Pennsylvania
Pennsylvania has 3,479 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.
Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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3,012 clinical trials
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Study of ORIC-944 in Patients With Metastatic Prostate Cancer
for Metastatic Prostate Cancer
Sites in Lancaster, Bala-Cynwyd +18 more locations
Sponsor: ORIC Pharmaceuticals
Sex: Male·Age: 18+
Code: NCT05413421·Phase 1·Recruiting·Listed Jun 2022
A Study to Find Out How Nusinersen is Processed in the Body When Given Through the ThecaFlex DRx™ System in Adult and Pediatric Participants With Spinal Muscular Atrophy (PIERRE-PK)
for Muscular Atrophy, Spinal
Sites in Philadelphia, Hershey +10 more locations
Sponsor: Biogen
Sex: All·Age: 3+
Code: NCT06555419·Phase 1·Recruiting·Listed Aug 2024
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
for B-cell Acute Lymphoblastic Leukemia
Sites in Philadelphia +16 more locations
Sponsor: Merck Sharp & Dohme LLC
Sex: All·Age: 6 Months - 25
Code: NCT06395103·Phase 1, Phase 2·Recruiting·Listed May 2024
A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)
for Thrombocytopenia, Neonatal Alloimmune
Drug: Nipocalimab
Sites in Philadelphia +11 more locations
Sponsor: Janssen Research & Development, LLC
Sex: Female·Age: 18 - 45
Code: NCT06533098·Phase 3·Recruiting·Listed Aug 2024
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
for Heart Failure
Sites in Philadelphia, Pittsburgh +18 more locations
Sponsor: Merck Sharp & Dohme LLC
Sex: All·Age: 29 Days - 17
Code: NCT05714085·Phase 2, Phase 3·Recruiting·Listed Feb 2023
A Study of JNJ-87189401 Combined With JNJ-78278343 for Advanced Prostate Cancer
for Prostatic Neoplasms
Sites in Philadelphia +11 more locations
Sponsor: Janssen Research & Development, LLC
Sex: Male·Age: 18+
Code: NCT06095089·Phase 1·Recruiting·Listed Oct 2023
RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus
for Systemic Lupus Erythematosus
Sites in Philadelphia +17 more locations
Sponsor: Cabaletta Bio
Sex: All·Age: 18 - 65
Code: NCT06121297·Phase 1, Phase 2·Recruiting·Listed Nov 2023
A Study to Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in Patients With Advanced Solid Tumors
for Solid Tumor
Sites in Philadelphia, Dallas +9 more locations
Sponsor: Genentech, Inc.
Sex: All·Age: 18+
Code: NCT06619587·Phase 1·Recruiting·Listed Oct 2024
A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease
for Crohn's Disease
Sites in Philadelphia +14 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 2 - 17
Code: NCT05509777·Phase 3·Recruiting·Listed Aug 2022
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
for Left Ventricular Systolic Dysfunction
Drug: Finerenone
Sites in Philadelphia, Pittsburgh +20 more locations
Sponsor: Bayer
Sex: All·Age: 6 Months - 17
Code: NCT07188805·Phase 3·Recruiting·Listed Sep 2025
A Follow-up Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia
for Immune Thrombocytopenic Purpura (ITP)
Sites in Philadelphia +19 more locations
Sponsor: Takeda
Sex: All·Age: 18+
Code: NCT06948318·Phase 3·Recruiting·Listed Apr 2025
A Study to Evaluate the Maintenance Effect of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
for Major Depressive Disorder
Drug: NBI-1065845
Sites in Philadelphia +21 more locations
Sponsor: Neurocrine Biosciences
Sex: All·Age: 18+
Code: NCT07196501·Phase 3·Recruiting·Listed Sep 2025
Onyx™ Liquid Embolic IDE Clinical Study
for Peripheral Arterial Hemorrhage
Sites in Pittsburgh +16 more locations
Sponsor: Medtronic Endovascular
Sex: All·Age: 22+
Code: NCT06742801·Recruiting·Listed Dec 2024
A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
for Head and Neck Squamous Cell Carcinoma (HNSCC)
Drug: Cemiplimab
Sites in Willow Grove +17 more locations
Sponsor: Regeneron Pharmaceuticals
Sex: All·Age: 18+
Code: NCT06769698·Phase 2·Recruiting·Listed Jan 2025
Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
for Non-Small Cell Lung Cancer (NSCLC)
Drug: daraxonrasib
Sites in Pittsburgh +19 more locations
Sponsor: Revolution Medicines, Inc.
Sex: All·Age: 18+
Code: NCT06128551·Phase 1, Phase 2·Recruiting·Listed Nov 2023
PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches
for Aneurysm
Sites in Philadelphia, Allentown +8 more locations
Sponsor: Vascutek Ltd.
Sex: All·Age: 18+
Code: NCT04545502·Recruiting·Listed Sep 2020
A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)
for Sickle Cell Disease
Sites in Philadelphia, Easton +14 more locations
Sponsor: Novartis Pharmaceuticals
Sex: All·Age: 12 - 100
Code: NCT06439082·Phase 3·Recruiting·Listed Jun 2024
A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)
for Relapsed or Refractory Multiple Myeloma (RRMM)
Sites in Pittsburgh +16 more locations
Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
Sex: All·Age: 18+
Code: NCT06615479·Phase 3·Recruiting·Listed Sep 2024
A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease
for Anemia, Sickle Cell
Sites in Philadelphia, Pittsburgh +16 more locations
Sponsor: Bristol-Myers Squibb
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT06481306·Phase 1, Phase 2·Recruiting·Listed Jul 2024
A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma
for Multiple Myeloma
Sites in Philadelphia +16 more locations
Sponsor: K36 Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT05651932·Phase 1·Recruiting·Listed Dec 2022
A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors
for Metastatic Solid Tumor
Sites in Pittsburgh +17 more locations
Sponsor: Coherus Oncology, Inc.
Sex: All·Age: 18+
Code: NCT06657144·Phase 1·Recruiting·Listed Oct 2024
A Study of Nipocalimab in Children Aged 2 to Less Than 18 Years With Generalized Myasthenia Gravis
for Myasthenia Gravis
Drug: Nipocalimab
Sites in Philadelphia, Hershey +6 more locations
Sponsor: Janssen Research & Development, LLC
Sex: All·Age: 2 - 17
Code: NCT05265273·Phase 2, Phase 3·Recruiting·Listed Mar 2022
A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms
for Neoplasms
Sites in Philadelphia +12 more locations
Sponsor: Janssen Research & Development, LLC
Sex: All·Age: 18+
Code: NCT06150157·Phase 1·Recruiting·Listed Nov 2023
Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis
for Sickle Cell Disease Vaso-occlusive Crisis
Sites in Pittsburgh +18 more locations
Sponsor: CSL Behring
Sex: All·Age: 12+
Code: NCT06699849·Phase 2·Recruiting·Listed Nov 2024
A Study of the Efficacy and Safety of Lisocabtagene Maraleucel (Liso-cel) as First-Line Therapy in Adults With Transplant-Ineligible Primary Central Nervous System Lymphoma
for Lymphoma
Sites in Philadelphia +13 more locations
Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
Sex: All·Age: 18+
Code: NCT07015242·Phase 2·Recruiting·Listed Jun 2025
Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer
for Extensive Stage Small Cell Lung Cancer (ES-SCLC)
Sites in Easton +22 more locations
Sponsor: Gilead Sciences
Sex: All·Age: 18+
Code: NCT06801834·Phase 3·Recruiting·Listed Jan 2025
Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer
for Ovarian Cancer
Sites in Pittsburgh +20 more locations
Sponsor: Regeneron Pharmaceuticals
Sex: Female·Age: 18+
Code: NCT06787612·Phase 2·Recruiting·Listed Jan 2025
A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1
for Neurofibromatosis Type 1
Sites in Philadelphia +13 more locations
Sponsor: Healx Limited
Sex: All·Age: 12+
Code: NCT06541847·Phase 2·Recruiting·Listed Aug 2024
A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia
for Immune Thrombocytopenic Purpura (ITP)
Sites in Philadelphia +23 more locations
Sponsor: Takeda
Sex: All·Age: 18+
Code: NCT06722235·Phase 3·Recruiting·Listed Dec 2024
Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen
for Carcinoid Syndrome
Sites in Philadelphia +16 more locations
Sponsor: Crinetics Pharmaceuticals Inc.
Sex: All·Age: 18+
Code: NCT07087054·Phase 3·Recruiting·Listed Jul 2025
Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)
for Central Line Associated Blood Stream Infections (CLABSI)
Sites in Philadelphia +15 more locations
Sponsor: CorMedix Therapeutics
Sex: All·Age: 18+
Code: NCT06822426·Phase 3·Recruiting·Listed Feb 2025
Study to Evaluate ARINA-1 in the Prevention of Bronchiolitis Obliterans Progression in Participants With Bilateral Lung Transplant
for Pre-Bronchiolitis Obliterans Syndrome
Sites in Philadelphia +19 more locations
Sponsor: Renovion, Inc.
Sex: All·Age: 18 - 75
Code: NCT05654922·Phase 3·Recruiting·Listed Dec 2022
Innovations in Genicular Outcomes Registry
for Knee Osteoarthritis
Sites in DuBois, State College +13 more locations
Sponsor: Pacira Pharmaceuticals, Inc
Sex: All·Age: All ages
Code: NCT05495334·Recruiting·Listed Aug 2022
The RAPID - PE Study: RESCUE Advanced Protocol for the Treatment of Pulmonary Embolism
for Pulmonary Embolism
Sites in Philadelphia +22 more locations
Sponsor: Thrombolex, Inc.
Sex: All·Age: All ages
Code: NCT06433011·Recruiting·Listed May 2024
A Study to Evaluate the Safety and Effectiveness of the Rapidlink Device When Used in Patients Undergoing an Open Surgical Procedure to Repair the Aorta
for Aortic Aneurysm
Sites in Philadelphia, Pittsburgh +13 more locations
Sponsor: Vascutek Ltd.
Sex: All·Age: 18+
Code: NCT07078383·Recruiting·Listed Jul 2025
Non-Invasive Preeclampsia Screening and Biobank
for Preeclampsia (PE)
Sites in Philadelphia, Danville +18 more locations
Sponsor: Sequenom, Inc.
Sex: Female·Age: 18+·Accepts healthy volunteers
Code: NCT06643741·Recruiting·Listed Oct 2024
Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF)
for Idiopathic Pulmonary Fibrosis
Sites in Philadelphia +17 more locations
Sponsor: Cumberland Pharmaceuticals
Sex: All·Age: 40+
Code: NCT05571059·Phase 2·Recruiting·Listed Oct 2022
A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes
for Diabetes Mellitus, Type 1
Sites in Philadelphia, Pittsburgh +8 more locations
Sponsor: Vertex Pharmaceuticals Incorporated
Sex: All·Age: 18 - 65
Code: NCT04786262·Phase 3·Recruiting·Listed Mar 2021
Study of Olutasidenib and Temozolomide in HGG
for High Grade Glioma
Sites in Philadelphia +10 more locations
Sponsor: Rigel Pharmaceuticals
Sex: All·Age: 12 - 39
Code: NCT06161974·Phase 2·Recruiting·Listed Dec 2023