Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,650 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 8, 2026.

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3,650 clinical trials

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Evaluation of Gadolinium Based Contrast Agents for Portable MR Imaging Systems

for Intra-axial Tumors

4 locations incl. Amherst

Sponsor: Hyperfine

Sex: All·Age: 18+

Code: NCT07296263·Enrolling By Invitation

Better Social, Emotional Communication, Healthy Relationship and ASD Accommodation Skills: Emotional Intelligence ("EQ") Training for Autistic People and ASD Accommodation Training for People Who Care

for Autism

1 location in Wexford

Sponsor: Kairon Connect, PBC

Sex: All·Age: 18+

Code: NCT07315867·Recruiting

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Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal Resections

for Colorectal Anastomosis

8 locations incl. New Haven

Sponsor: Medtronic - MITG

Sex: All·Age: 18+

Code: NCT07351071·Recruiting

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Optimizing Pain Treatment in Children On Mechanical Ventilation

for Mechanical Ventilation

15 locations incl. Little Rock

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 2 Months - 17

Code: NCT06994442·Phase 3·Recruiting

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A Dose-ranging Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Galvokimig in Adult Study Participants With Atopic Dermatitis

for Atopic Dermatitis

20 locations incl. Oceanside

Sponsor: UCB Biopharma SRL

Sex: All·Age: 18+

Code: NCT07277660·Phase 2·Recruiting

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Diagnosing Epilepsy To EffeCT Change

for Epilepsy

18 locations incl. Phoenix

Sponsor: Epiminder America, Inc.

Sex: All·Age: 18 - 75

Code: NCT07110337·Recruiting

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Evaluation of a Peer Recovery Support Program Adapted to Target Retention in Clinic-based Medication for Opioid Use Disorder Treatment

for Opioid Use Disorder

1 location in Danville

Sponsor: Geisinger Clinic

Sex: All·Age: 18 - 89

Code: NCT07197801·Recruiting

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Clinical Trial to Evaluate Post-Operative Outcomes of Ureteral Stent vs Ureteral Stent Free Radical Cystectomy

for Bladder Cancer

2 locations incl. Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18 - 85

Code: NCT07234968·Recruiting

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Psilocybin on Brain Mechanisms of Motivation in OUD

for Opioid Use Disorder

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 60

Code: NCT06810310·Phase 2·Recruiting

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A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

for Breast Neoplasms

117 locations incl. Anchorage

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07174336·Phase 3·Recruiting

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A Study to Investigate the Clinical Effect and the Safety of PRX-115 Infused Intravenously at Different Dosing Regimens, With and Without Methotrexate, Versus Placebo in Adults Gout Patients (RELEASE)

for Gout

18 locations incl. Little Rock

Sponsor: Protalix

Sex: All·Age: 18+

Code: NCT07280156·Phase 2·Recruiting

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Study of ENV-294 in Adults With Moderate-to-Severe Atopic Dermatitis

for Atopic Dermatitis (AD)

23 locations incl. Birmingham

Sponsor: Enveda Therapeutics

Sex: All·Age: 18 - 75

Code: NCT07298395·Phase 2·Recruiting

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A Study to Evaluate the Safety and Effectiveness of the Rapidlink Device When Used in Patients Undergoing an Open Surgical Procedure to Repair the Aorta

for Aortic Aneurysm

16 locations incl. Los Angeles

Sponsor: Vascutek Ltd.

Sex: All·Age: 18+

Code: NCT07078383·Recruiting

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A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer

for Prostatic Neoplasms, Castration-Resistant

Drug: Pasritamig

49 locations incl. Chandler

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07225946·Phase 3·Recruiting

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Study is to Assess the Safety and Tolerability of VTx-002 in Participants With ALS

for Amyotrophic Lateral Sclerosis

7 locations incl. Phoenix

Sponsor: Vector Y Therapeutics

Sex: All·Age: 18+

Code: NCT07287397·Phase 1, Phase 2·Recruiting

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A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy

for Spinal Muscular Atrophy (SMA)

17 locations incl. Little Rock

Sponsor: argenx

Sex: All·Age: 5 - 17

Code: NCT07287982·Phase 2·Recruiting

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NEXUS Study: A Study to Test Single and Multiple Doses of MER511 Given to Adults With Graves' Disease

for Graves Disease

8 locations incl. Phoenix

Sponsor: Merida Biosciences

Sex: All·Age: 18 - 55

Code: NCT07305818·Phase 1·Recruiting

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Intervascular Post-Market Clinical Follow-Up (PMCF) Registry

for Carotid Artery Diseases

1 location in Pittsburgh

Sponsor: Intervascular

Sex: All·Age: 18+

Code: NCT07322913·Recruiting

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Ruxolitinib in Previously Treated Idiopathic Multicentric Castleman Disease

for Castleman's Disease (CD)

Drug: Ruxolitinib

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 80

Code: NCT07085039·Phase 2·Recruiting

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A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062)

for Human Immunodeficiency Virus Type 1 (HIV-1) Infection

23 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07266831·Phase 2, Phase 3·Recruiting

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Evaluation of Analgesia for Cardiac Elective Surgery in Children

for Pediatric Cardiac Surgery

1 location in Pittsburgh

Sponsor: Senthil Sadhasivam

Sex: All·Age: 3 - 18

Code: NCT06626035·Phase 3·Recruiting

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Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations

for Non-Small-Cell Lung Cancer

15 locations incl. Los Angeles

Sponsor: ArriVent BioPharma, Inc.

Sex: All·Age: 18+

Code: NCT07185997·Phase 3·Recruiting

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Left Atrial Strain and Cryptogenic Stroke

for Ischemic Stroke, Cryptogenic

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT07224178·Recruiting

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F-PGT - Prolonged Grief Treatment for Families Affected by Suicide

for Prolonged Grief Disorder (PGD)

2 locations incl. New York

Sponsor: University of Pittsburgh

Sex: All·Age: 8+

Code: NCT07318090·Enrolling By Invitation

Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

for Non-small Cell Lung Cancer

61 locations incl. Oak Brook

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT06686771·Phase 3·Recruiting

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Study of DONQ52 in Active Celiac Disease

for Celiac Disease

Drug: DONQ52

49 locations incl. Anniston

Sponsor: Chugai Pharmaceutical

Sex: All·Age: 18 - 75

Code: NCT07239336·Phase 2·Recruiting

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A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression

for Major Depressive Disorder (MDD)

23 locations incl. Bentonville

Sponsor: Draig Therapeutics Ltd

Sex: All·Age: 18 - 75

Code: NCT07300969·Phase 2·Recruiting

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B.Brilliant Revelation Comparision Study

for Breast Cancer Screening

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT07067788·Recruiting

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Menstrual Cycle TMS Plasticity Pilot

for Cortical Activation

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 20 - 40·Accepts healthy volunteers

Code: NCT07180654·Recruiting

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A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures

for Focal Epilepsy

7 locations incl. Boise

Sponsor: Rapport Therapeutics Inc.

Sex: All·Age: 18 - 70

Code: NCT07219407·Phase 2·Recruiting

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A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

for Overweight

Drug: Eloralintide

60 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07282600·Phase 3·Recruiting

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A Clinical Study to Evaluate the Effect and Side Effect of a New Artificial Tear Formulation (ABBV-444) Compared to Refresh Optive Unit Dose in Adult Participants With Dry Eye Disease

for Dry Eye Disease

20 locations incl. Dothan

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07284381·Phase 3·Recruiting

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A Long-term Follow-up Study in Patients Who Received BEAM-101

for Hemoglobinopathy

17 locations incl. Birmingham

Sponsor: Beam Therapeutics Inc.

Sex: All·Age: 14 - 37

Code: NCT07373639·Recruiting

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A Randomized Phase III Study of Management of Treatment Naive Primary Melanoma in Elderly Patients

for Cutaneous Melanoma

1 location in Pittsburgh

Sponsor: Eastern Cooperative Oncology Group

Sex: All·Age: 75+

Code: NCT07068074·Phase 3·Not Yet Recruiting

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

for Carcinoma, Transitional Cell

60 locations incl. Huntsville

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07218380·Phase 3·Recruiting

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Single-Arm Study of a Treatment for Dry Eye in People Who Struggle to Wear Contact Lenses

for Dry Eye

1 location in Kingston

Sponsor: Vision Innovation Centers of Pennsylvania, LLC d/b/a Eye Care Specialists

Sex: All·Age: 22+

Code: NCT07510620·Phase 4·Recruiting

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Intra-Arterial Tenecteplase to Improve the Microvascular Hemodynamics After Mechanical Thrombectomy

for Acute Ischemic Stroke From Large Vessel Occlusion

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06904911·Phase 2·Recruiting

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Placebo-Controlled Trial of IFx-Hu2.0 Followed By Pembrolizumab In Checkpoint Inhibitor Naïve Participants With Advanced Or Metastatic Merkel Cell Carcinoma

for Advanced Or Metastatic Merkel Cell Carcinoma

18 locations incl. Los Angeles

Sponsor: TuHURA Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT06947928·Phase 2, Phase 3·Recruiting

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Tocilizumab Discontinuation Versus Dose Reduction for Patients With Well-Controlled Giant Cell Arteritis

for Giant Cell Arteritis (GCA)

Drug: Tocilizumab

7 locations incl. Atlanta

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 50+

Code: NCT07108387·Phase 2·Recruiting

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Prunes Preventing Bone Loss in Perimenopause

for Perimenopausal Bone Loss

1 location in University Park

Sponsor: Penn State University

Sex: Female·Age: 44 - 55·Accepts healthy volunteers

Code: NCT07120997·Recruiting

Apply to this trial