Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,659 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 4, 2026.

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3,659 clinical trials

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Care Coordination and Passive Mobile Data Monitoring to Improve Mental Health Care

for Severe Mental Illness

2 locations incl. West Los Angeles

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT07549178·Not Yet Recruiting

Prescribe to Prevent HIV: A Hybrid Trial Helping Addiction Clinics Prevent HIV & Infections Through Safer Drug Use Support

for People Who Use Opioids/People With Opioid Use Disorder (OUD)

4 locations incl. Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT07073924·Not Yet Recruiting

Lions Hearts: A Community Approach to Multigenerational Cardiovascular Disease Risk

for Cardiovascular (CV) Risk

1 location in State College

Sponsor: Penn State University

Sex: All·Age: 10+·Accepts healthy volunteers

Code: NCT07147387·Not Yet Recruiting

Testing a Mobile Health Application to Improve HIV Prevention and Substance Use Treatment Among Women Involved in the Carceral System

for Substance Abuse

1 location in Philadelphia

Sponsor: Temple University

Sex: Female·Age: 18+

Code: NCT07432555·Not Yet Recruiting

SnapChole: An International, Time-Bound Prospective Platform Study of Management Strategies and Outcomes in Acute Calculous Cholecystitis

for Cholecystitis, Acute

1 location in Philadelphia

Sponsor: European Society for Trauma and Emergency Surgery

Sex: All·Age: 18+

Code: NCT07568080·Not Yet Recruiting

Real-time Engagement for Learning to Effectively Control Type 2 Diabetes

for Diabetes Mellitus, Type 2

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 16 - 24

Code: NCT06375460·Not Yet Recruiting

Improving the Quality of Care for Asthma Patients at Risk of Exacerbations

for Asthma

6 locations incl. New Haven

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 75

Code: NCT06596512·Not Yet Recruiting

Study to Evaluate the Use of Triheptanoin in Patients With Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD)

for Medium-chain Acyl-CoA Dehydrogenase Deficiency

1 location in Pittsburgh

Sponsor: Jerry Vockley, MD, PhD

Sex: All·Age: 4+

Code: NCT07097311·Phase 2·Recruiting

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NANT 2021-02: Randomized MIBG With Vorinostat/Dinutuximab/Vorinostat + Dinutuximab

for Neuroblastoma

Drug: Vorinostat

13 locations incl. Los Angeles

Sponsor: New Approaches to Neuroblastoma Therapy Consortium

Sex: All·Age: 1 - 30

Code: NCT07261241·Phase 2·Not Yet Recruiting

Psilocybin After Trauma Surgery for Pain

for Pain Management

1 location in Pittsburgh

Sponsor: Trent Emerick

Sex: All·Age: 25 - 65

Code: NCT07406828·Phase 1·Not Yet Recruiting

CD45BE-HSPC + CART-45 Cells

for B-Cell Non-Hodgkin Lymphoma (NHL)

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07451054·Phase 1·Not Yet Recruiting

Tirzepatide Following Adrenalectomy in Mild Autonomous Cortisol Secretion

for Mild Autonomous Cortisol Secretion (MACS)

Drug: Tirzepatide

1 location in Pittsburgh

Sponsor: Alaa Sada

Sex: All·Age: 18+

Code: NCT07573163·Phase 2·Not Yet Recruiting

TCR1188-ABC Cells in KRAS-mutated Cancers

for Cholangiocarcinoma

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07594067·Phase 1·Not Yet Recruiting

Tiprelestat Versus Placebo When Added to Standard of Care for the Treatment of Pulmonary Arterial Hypertension (PAH)

for Pulmonary Arterial Hypertension (PAH)

10 locations incl. Tucson

Sponsor: Stanford University

Sex: All·Age: 18 - 75

Code: NCT07601295·Phase 2·Not Yet Recruiting

Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG

for Glioma

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 1 - 21

Code: NCT05555550·EARLY_Phase 1·Recruiting

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A Study to Find Out How Nerandomilast is Tolerated, Handled by the Body, and if it Helps Children and Adolescents With Interstitial Lung Disease (FIBRONEER-chILD)

for Fibrosing Interstitial Lung Disease

Drug: Nerandomilast

7 locations incl. Los Angeles

Sponsor: Boehringer Ingelheim

Sex: All·Age: 2 - 17

Code: NCT07366034·Phase 3·Not Yet Recruiting

A Study to Find the Highest Dose of Cedazuridine and Decitabine Combination With Filgrastim as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With High-Risk Acute Myeloid Leukemia

for Acute Myeloid Leukemia Post Cytotoxic Therapy

2 locations incl. Philadelphia

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 21

Code: NCT07012044·Phase 1·Recruiting

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Exercise-based Frailty Intervention in Lung Transplantation (XFIT)

for Frailty

4 locations incl. San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18 - 75

Code: NCT06960421·Not Yet Recruiting

Improving Heart Health in Individuals With SCI Using Home-Based Virtual Gaming

for Spinal Cord Injuries (SCI)

1 location in Philadelphia

Sponsor: Drexel University

Sex: All·Age: 18+

Code: NCT06690372·Recruiting

Apply to this trial

Behavioral and/or Mirabegron to Treat Urinary Symptoms in Parkinson Disease

for Overactive Bladder

3 locations incl. Decatur

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT07187466·Phase 4·Not Yet Recruiting

Transition From Acute to Chronic Opioid Use and Chronic Pain

for Opioid Use Disorder

1 location in Pittsburgh

Sponsor: Jacques E. Chelly

Sex: All·Age: 18+

Code: NCT07211399·EARLY_Phase 1·Not Yet Recruiting

Cessation or Reduction of Alcohol Consumption in Veterans: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial to Evaluate the Efficacy and Safety of a GLP-1 Receptor Agonist Semaglutide in U.S. Veterans With Alcohol Use Disorder

for Alcohol Use Disorder

Drug: Semaglutide

1 location in Philadelphia

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT07218354·Phase 3·Not Yet Recruiting

Development of an Eating Behavior Risk Score

for Obesity

1 location in State College

Sponsor: Penn State University

Sex: All·Age: 7 - 9·Accepts healthy volunteers

Code: NCT07266506·Not Yet Recruiting

COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE"

for New Onset Refractory Status Epilepticus

Drug: Tocilizumab

25 locations incl. Phoenix

Sponsor: Yale University

Sex: All·Age: 2+

Code: NCT07281027·Phase 3·Not Yet Recruiting

Testing the Use of VA Peer Specialists to Prevent Veteran Suicide

for Suicide Risk

3 locations incl. Baltimore

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT07286383·Phase 3·Not Yet Recruiting

Effect of cTBS on Startle and TMS-evoked BOLD

for Anxiety

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT07415772·Not Yet Recruiting

Validation of NAD+ Measurements for Human Clinical Studies

for Healthy Adults

2 locations incl. Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 110·Accepts healthy volunteers

Code: NCT07416786·Not Yet Recruiting

Efficacy of Integrating Next Generation Sequencing for Treatment of Surgical Site Infection After Fracture Fixation:

for Next Generation Sequencing (NGS)

18 locations incl. Tuscaloosa

Sponsor: Johns Hopkins Bloomberg School of Public Health

Sex: All·Age: 18 - 84

Code: NCT07458230·Phase 3·Not Yet Recruiting

DaxibotulinumtoxinA for Blepharospasm

for Blepharospasm of Both Eyelids

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07489430·Phase 2·Not Yet Recruiting

Testing an Adaptive Intervention for Peer-Supported Mobile Health for Primary Care Veterans With Psychological Distress

for Psychological Distress

5 locations incl. Palo Alto

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT07507747·Not Yet Recruiting

Optimizing Stimulation Parameters for Electroconvulsive Therapy

for Depression - Major Depressive Disorder

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: All ages

Code: NCT07561307·Not Yet Recruiting

The Effects of Timolol On Healing and Cosmesis of Mohs Scalp Wounds: An Open Label Trial

for Surgical Wounds

1 location in Danville

Sponsor: Geisinger Clinic

Sex: All·Age: 18+

Code: NCT07583862·Phase 2·Not Yet Recruiting

A Widely Inclusive, Hybrid-Decentralized Pilot Trial Utilizing β-hydroxy-β-methylbutyrate to Lower IGFBP7 Levels in People With ALS

for Amyotrophic Lateral Sclerosis ALS

2 locations incl. Durham

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT07589764·Phase 1·Not Yet Recruiting

mHealth Service Linkage for Young Adults Impacted by the Criminal Legal System

for HIV Prevention

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 29·Accepts healthy volunteers

Code: NCT07599722·Not Yet Recruiting

TRACK-TBI Precision Medicine Part 3 - Option II

for Traumatic Brain Injury

2 locations incl. San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18 - 65

Code: NCT06790095·Phase 2·Enrolling By Invitation

Effects of Ketones on Brain Energetics and Alcohol Consumption in Alcohol Use Disorder

for Alcohol Use Disorder

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 21 - 65

Code: NCT06807918·Phase 2, Phase 3·Not Yet Recruiting

The Effect of SPecialty cAre on Recovery From Cardiac Arrest Trial (the SPARC Trial)

for Cardiac Arrest (CA)

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT07002294·Not Yet Recruiting

A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 )

for Lymphoma, Non-Hodgkin

23 locations incl. Duarte

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07101328·Phase 1·Not Yet Recruiting

Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up

for Epilepsy

12 locations incl. Phoenix

Sponsor: Epiminder America, Inc.

Sex: All·Age: 18 - 75

Code: NCT07110454·Recruiting

Apply to this trial

Plasma Resuscitation Early for Evaluating Volume and Endotheliopathy of Thermal Injury (PREEVEnT) Trial

for Burn Injury

1 location in Pittsburgh

Sponsor: Jason Sperry

Sex: All·Age: 18 - 75

Code: NCT07212998·Phase 3·Not Yet Recruiting