Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,659 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 4, 2026.

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3,659 clinical trials

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Novel Self-charging, Medical-Grade Smart Insoles With AI/ML Edge Computing to Monitor Biometrics.

for No Applicable Condition

1 location in Williamsport

Sponsor: Spectrum Ergonomics and Occupational Health Services

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT07273422·Recruiting

Apply to this trial

Investigating Real-Time Immunotherapy Symptoms Study

for Cancer

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT07280715·Not Yet Recruiting

A Trial to Evaluate Ovarian Suppression Following Subcutaneous ZOLADEX 10.8 mg in Premenopausal Women With HR+, HER2- Advanced Breast Cancer

for Advanced Breast Cancer

11 locations incl. Hot Springs

Sponsor: TerSera Therapeutics LLC

Sex: Female·Age: 18 - 55

Code: NCT07310420·Phase 1·Recruiting

Apply to this trial

A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications

for Parkinson's Disease

26 locations incl. Phoenix

Sponsor: Bayer

Sex: All·Age: 45 - 75

Code: NCT07330258·Recruiting

Apply to this trial

A Study of CDX-622 in Participants With Mild to Moderate Asthma

for Mild to Moderate Asthma

4 locations incl. San Francisco

Sponsor: Celldex Therapeutics

Sex: All·Age: 18+

Code: NCT07330778·Phase 1·Recruiting

Apply to this trial

Topical Cryotherapy and Keloid/Hypertrophic Scars

for Keloid Scars

1 location in Pittsburgh

Sponsor: Sonal Choudhary

Sex: All·Age: 18+

Code: NCT07336368·Phase 3·Recruiting

Apply to this trial

Sleep and Circadian Interventions for College Students at High Risk of Suicide

for Sleep Disturbance

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 25

Code: NCT07346014·Not Yet Recruiting

Study of ALK-001 on the Progression of Stargardt Disease

for Stargardt Disease

4 locations incl. Phoenix

Sponsor: Alkeus Pharmaceuticals, Inc.

Sex: All·Age: 8 - 45

Code: NCT07419334·Phase 3·Recruiting

Apply to this trial

T4/T3 Therapy in Hypothyroidism

for Hypothyroidism Primary

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 70

Code: NCT07424183·Phase 2·Not Yet Recruiting

NeuroCuple to Mitigate Post-Wisdom Teeth Extraction Opioid Risks

for Wisdom Teeth

1 location in Pittsburgh

Sponsor: nCap Medical

Sex: All·Age: 18 - 50

Code: NCT07461506·Not Yet Recruiting

H&N NEO-COMBAT XL: Neoadjuvant XL-092 (Zanzalintinib) and Pembrolizumab (Keytruda) in Surgically Resectable, HPV Negative Oral Cavity Squamous Cell Carcinoma (OCSCC)

for Oral Cavity Squamous Cell Carcinoma

3 locations incl. Atlanta

Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07484139·Phase 2·Not Yet Recruiting

Pharmacokinetics, Pharmacodynamics, Safety and Tolerability Evaluation of CTAP101 Extended-release Capsules in Pediatric Participants

for CKD Stage 3

5 locations incl. Kansas City

Sponsor: OPKO Health, Inc.

Sex: All·Age: 1 Month - 17

Code: NCT07494045·Phase 2·Not Yet Recruiting

Nanozymes in Endodontics

for Apical Periodontitis

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07518901·Phase 4·Not Yet Recruiting

Impact of Loss Aversion Messaging and Anticipated Regret for Inaction on Exercise Adherence in Older Adults

for Mobility Disability

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 65+

Code: NCT07540052·Not Yet Recruiting

Bilevel Positive Airway Pressure (BPAP) for Severe Asthma

for Pediatric Asthma

3 locations incl. New York

Sponsor: Columbia University

Sex: All·Age: 5 - 17

Code: NCT07582211·Not Yet Recruiting

Safety And Tolerability Of Gamma Glutamylcysteine (GGC) Oral Supplementation In MCI Patients

for Mild Cognitive Impairment (MCI)

1 location in Pittsburgh

Sponsor: Pravat Mandal

Sex: All·Age: 55 - 80

Code: NCT07583251·Phase 1·Recruiting

Apply to this trial

Automated IADL Sensing to Refine Measurement of Older Adult Daily Activity

for Cognitive Ability General

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Female·Age: 75+·Accepts healthy volunteers

Code: NCT07585864·Not Yet Recruiting

Periprosthetic Joint Infection Bubble Study

for Periprosthetic Joint Infection (PJI)

2 locations incl. Pittsburgh

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07599865·Phase 2·Not Yet Recruiting

A Study in Adults With Geographic Atrophy

for Geographic Atrophy

20 locations incl. Bakersfield

Sponsor: Sitala Bio LTD

Sex: All·Age: 60+

Code: NCT07606365·Phase 2·Not Yet Recruiting

A Study to Evaluate the Efficacy and Safety of Concomitant Use of Eplontersen and ALXN2220 Compared With Eplontersen and Placebo for Adults Participants With ATTR-CM.

for Transthyretin Amyloid Cardiomyopathy (ATTR-CM)

24 locations incl. La Jolla

Sponsor: AstraZeneca

Sex: All·Age: 18 - 85

Code: NCT07608354·Phase 2·Not Yet Recruiting

FG001 Near-Infrared Fluorescence Imaging During Tumor Resection in Newly Diagnosed High-Grade Glioma

for High-Grade Glioma (WHO III-IV)

5 locations incl. Miami

Sponsor: FluoGuide A/S

Sex: All·Age: 18+

Code: NCT07609472·Phase 2·Not Yet Recruiting

Impact of Electronic Cigarette Temperature and Solvent on Biomarkers

for Oxidative Stress

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 21+

Code: NCT07612696·Not Yet Recruiting

An International Multicenter, Multivendor Evaluation of the Free-Running Framework for Cardiac Function

for Congenital Heart Diseases

9 locations incl. Los Angeles

Sponsor: Matthias Stuber

Sex: All·Age: All ages

Code: NCT07613398·Not Yet Recruiting

Decision Counseling and Follow-up for Shield+ Patients

for Colo-rectal Cancer

1 location in Philadelphia

Sponsor: Guardant Health, Inc.

Sex: All·Age: 45 - 75·Accepts healthy volunteers

Code: NCT07620535·Not Yet Recruiting

Small Trial of Alendronate Impact on the Reservoir of HIV

for HIV

5 locations incl. San Francisco

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 65

Code: NCT07216794·Phase 2·Not Yet Recruiting

A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events

for Atherosclerosis

6 locations incl. Beverly Hills

Sponsor: Genentech, Inc.

Sex: All·Age: 18 - 80

Code: NCT07448038·Phase 2·Recruiting

Apply to this trial

DAREON®-NEC-1: A Study in People With Advanced Extrapulmonary Neuroendocrine Cancer to Compare Obrixtamig Plus Carboplatin and Etoposide Treatment With Standard Chemotherapy

for Extrapulmonary Neuroendocrine Cancer

Drug: Obrixtamig

20 locations incl. Scottsdale

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07544654·Phase 3·Not Yet Recruiting

A Study to Access Activity and Safety With SAR445399 Compared With Placebo in Participants Aged 18 to 80 Years of Age With Non-Cystic Fibrosis Bronchiectasis

for Non-cystic Fibrosis Bronchiectasis

Drug: SAR445399

3 locations incl. Loxahatchee Groves

Sponsor: Sanofi

Sex: All·Age: 18 - 80

Code: NCT07547436·Phase 2·Recruiting

Apply to this trial

A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection

for HIV-1-infection

10 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 70

Code: NCT06987318·Phase 1·Not Yet Recruiting

tSCS in Children With Spina Bifida

for Spina Bifida

1 location in Pittsburgh

Sponsor: Bailey Petersen

Sex: All·Age: 4 - 17

Code: NCT07615686·Recruiting

Apply to this trial

A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis

for Systemic Sclerosis

Drug: Nerandomilast

30 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07497087·Phase 3·Not Yet Recruiting

RCT to Assess the Efficacy of Biophoton Therapy to Treat Type 2 Diabetes

for Type 2 Diabetes

2 locations incl. Tampa

Sponsor: First Institute of All Medicines

Sex: All·Age: 18 - 70

Code: NCT07124208·Not Yet Recruiting

Evaluation of the Efficacy, Safety, and Tolerability of LevoCept

for Contraception

27 locations incl. Berkeley

Sponsor: Sebela Women's Health Inc.

Sex: Female·Age: Up to 45·Accepts healthy volunteers

Code: NCT04457076·Phase 3·Not Yet Recruiting

Interpersonal Communication Training and Vaccination Workflow Training Alone and in Combination to Improve Communication and Recommendations About HPV Vaccination in Pharmacies, IMPACT HPV Trial

for Human Papillomavirus-Related Carcinoma

2 locations incl. University Park

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06926062·Not Yet Recruiting

A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

for Left Ventricular Systolic Dysfunction

Drug: Finerenone

22 locations incl. Aurora

Sponsor: Bayer

Sex: All·Age: Up to 18

Code: NCT07192952·Phase 3·Not Yet Recruiting

Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression

for Major Depression

5 locations incl. Birmingham

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75

Code: NCT07226232·Phase 3·Not Yet Recruiting

Autologous Fat Grafting Beneath Penile Split Thickness Skin Graft Placement During Penile Reconstruction

for Penis/Surgery

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Male·Age: 18+

Code: NCT07316491·Not Yet Recruiting

Do Video Recordings of Multidisciplinary Clinics Improve Quality of Life for People With ALS and Their Caregivers?

for Amyotrophic Lateral Sclerosis (ALS)

7 locations incl. Scottsdale

Sponsor: Trustees of Dartmouth College

Sex: All·Age: 18+

Code: NCT07454733·Not Yet Recruiting

Pilot and Feasibility Study of Intra-articular Anti-CD14 for the Treatment of Knee Osteoarthritis

for Knee Osteoarthritis (Knee OA)

1 location in Philadelphia

Sponsor: VA Office of Research and Development

Sex: All·Age: 50 - 80

Code: NCT07481474·Phase 1·Not Yet Recruiting

A Phase 2 Clinical Study to Evaluate the Efficacy and Safety of Frevecitinib (KN-002) in Patients With Severe Asthma

for Severe Asthma

Drug: Frevecitinib

15 locations incl. Lancaster

Sponsor: Kinaset Therapeutics Inc

Sex: All·Age: 18 - 75

Code: NCT07532265·Phase 2·Not Yet Recruiting