Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,650 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 8, 2026.

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3,650 clinical trials

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A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)

for Hypothalamic Obesity

8 locations incl. Birmingham

Sponsor: Rhythm Pharmaceuticals, Inc.

Sex: All·Age: 4+

Code: NCT06760546·Phase 3·Recruiting

Apply to this trial

A Study of DB-1317 in Selected Advanced/Metastatic Solid Tumors

for Advanced/Metastatic Solid Tumors

5 locations incl. Los Angeles

Sponsor: DualityBio Inc.

Sex: All·Age: 18+

Code: NCT07141706·Phase 1·Recruiting

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Circulating Tumor DNA in High Risk Localized Prostate Cancer

for Prostate Cancer

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Male·Age: 18+

Code: NCT07222436·Recruiting

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GORE® Ascending Stent Graft in the Treatment of De Novo Type A Aortic Dissections

for Aortic Dissection

16 locations incl. Birmingham

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT06827990·Recruiting

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9-ING-41 Combined With Retifanlimab, Plus Modified FOLFIRINOX for Patients With Advanced Pancreatic Adenocarcinoma (RiLEY)

for Pancreatic Adenocarcinoma

Drug: Retifanlimab

1 location in Pittsburgh

Sponsor: Anwaar Saeed

Sex: All·Age: 18+

Code: NCT06896188·Phase 1·Recruiting

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A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.

for Chronic Obstructive Pulmonary Disease

Drug: Dupilumab

9 locations incl. Birmingham

Sponsor: Sanofi

Sex: All·Age: 40 - 85

Code: NCT07053423·Phase 4·Recruiting

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Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)

for Plaque Psoriasis

Drug: Deucravacitinib

122 locations incl. Birmingham

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 40+

Code: NCT07116967·Phase 3·Recruiting

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Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

for High Risk Cardiovascular Disease

Drug: Zilebesiran

247 locations incl. Birmingham

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07181109·Phase 3·Recruiting

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Study to Evaluate the Efficacy and Safety of VQW-765 for the On-Demand Treatment of Social Anxiety Disorder

for Social Anxiety Disorder (SAD)

30 locations incl. Phoenix

Sponsor: Vanda Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT07221578·Phase 3·Recruiting

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Continuous Jugular Venous Oxygen Saturation (SjO2) Measurement After Cardiac Arrest

for Cardiac Arrest

1 location in Pittsburgh

Sponsor: Byron Drumheller

Sex: All·Age: 18+

Code: NCT06511999·Recruiting

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Use of Wearables Following Cystectomy- Part II

for Bladder Cancer

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT07148765·Enrolling By Invitation

Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

for Cystic Fibrosis (CF)

18 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 12+

Code: NCT06837181·Recruiting

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DESTINY-PANTUMOUR04

for Adenocarcinoma (NOS)

17 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT07124000·Recruiting

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Non-Invasive Interventions for Respiratory Recovery in Chronic Spinal Cord Injury

for Spinal Cord Injury, Chronic

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18 - 70

Code: NCT07135583·Recruiting

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LTFU for All Cell and Gene Therapy Studies

for Hepatocellular Carcinoma

18 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06194461·Not Yet Recruiting

ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

for Anatomic Stage I Breast Cancer AJCC v8

652 locations incl. Phoenix

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06876714·Phase 3·Recruiting

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Evaluation of Potassium (K) and Ionized Calcium (iCa) Tests Using Capillary Specimens

for Hematologic Tests

3 locations incl. Albuquerque

Sponsor: Abbott Point of Care

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07287618·Recruiting

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Clinical Evaluation of Precision for the Potassium and Ionized Calcium Tests in Capillary Specimens

for Hematologic Tests

3 locations incl. Albuquerque

Sponsor: Abbott Point of Care

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07287631·Recruiting

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UnityPhilly Response App for Overdose Reversal

for Opioid Overdose

1 location in Philadelphia

Sponsor: Drexel University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06466005·Recruiting

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A Study of Tarlatamab in Combination With AB248 in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-311)

for Extensive Stage Small Cell Lung Cancer

Drug: Tarlatamab

13 locations incl. Gilbert

Sponsor: Amgen

Sex: All·Age: 18 - 90

Code: NCT07037758·Phase 1·Recruiting

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A Study to Assess the Efficacy and Safety of Empasiprubart in Adults With CIDP

for Chronic Inflammatory Demyelinating Polyneuropathy

9 locations incl. Rancho Mirage

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT07091630·Phase 3·Recruiting

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Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype

for Chronic Obstructive Pulmonary Disease

Drug: Lunsekimig

63 locations incl. Chandler

Sponsor: Sanofi

Sex: All·Age: 40 - 80

Code: NCT07190209·Phase 3·Recruiting

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RISE Versus Advocacy-based Enhanced Care as Usual for Patients Experiencing IPV

for Intimate Partner Violence (IPV)

3 locations incl. Boston

Sponsor: Boston University

Sex: All·Age: 18+

Code: NCT06906302·Recruiting

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A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy

for Spinal Muscular Atrophy

Drug: Apitegromab

14 locations incl. Phoenix

Sponsor: Scholar Rock, Inc.

Sex: All·Age: Up to 2

Code: NCT07047144·Phase 2·Recruiting

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Efficacy and Safety of 4F-PCC (4-Factor Prothrombin Complex Concentrate) in Adult Patients Undergoing Complex Cardiovascular Surgery With Cardiopulmonary Bypass (CPB)

for Complex Cardiovascular Surgery With Cardiopulmonary Bypass

10 locations incl. Los Angeles

Sponsor: CSL Behring

Sex: All·Age: 18+

Code: NCT07094087·Phase 3·Recruiting

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A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee

for Osteoarthritis

Drug: Orforglipron

26 locations incl. Phoenix

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07153471·Phase 3·Recruiting

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Motivation for Daily Living Skills

for Autism Spectrum Disorder (ASD)

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 16 - 25

Code: NCT07159308·Recruiting

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Foundational Programs to Combat Clinician Stress

for Burnout, Professional

6 locations incl. Boston

Sponsor: Lancaster General Hospital

Sex: All·Age: 25 - 70·Accepts healthy volunteers

Code: NCT07220421·Recruiting

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5-Year Postoperative Outcomes of Patients Who Completed the CREST Study

for Open-angle Glaucoma (OAG)

10 locations incl. Newport Beach

Sponsor: Iantrek, Inc.

Sex: All·Age: All ages

Code: NCT07480343·Enrolling By Invitation

Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706

for HIV Infections

7 locations incl. San Francisco

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06665646·Phase 1·Recruiting

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Data Collection Using Eko Digital Devices in a Clinical Setting

for Lung Diseases

2 locations incl. Jacksonville

Sponsor: Eko Devices, Inc.

Sex: All·Age: All ages

Code: NCT07227376·Recruiting

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A Study to Test Whether Nerandomilast Helps People With Lungfibrosis Related to Rheumatic Diseases

for Interstitial Lung Diseases

Drug: Nerandomilast

33 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06806592·Phase 3·Recruiting

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A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

for Breast Neoplasms

46 locations incl. Hot Springs

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT06926868·Phase 2, Phase 3·Recruiting

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A 16-week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream 20 mg/g in Adult Participants With Mild to Severe Palmoplantar Pustulosis

for Palmoplantar Pustulosis

7 locations incl. Fountain Valley

Sponsor: LEO Pharma

Sex: All·Age: 18+

Code: NCT07013201·Phase 2·Recruiting

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Y-90 Treatment Response Using Transarterial Radioembolization

for HCC

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07145801·Phase 2·Recruiting

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A Study to Evaluate TAR-210 Versus Intravesical Chemotherapy Treatment in Participants With High Risk Non-Muscle-Invasive Bladder Cancer

for Non-Muscle Invasive Bladder Neoplasms

22 locations incl. Sun City

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06919965·Phase 3·Recruiting

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A Long-Term Study to Learn About The Study Medicine Called Ritlecitinib in Children With Severe Alopecia Areata.

for Severe Alopecia Areata

Drug: Ritlecitinib

18 locations incl. Encinitas

Sponsor: Pfizer

Sex: All·Age: 6 - 14

Code: NCT07029828·Phase 3·Recruiting

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Pembrolizumab and Odetiglucan in Liver Predominant Metastatic Colorectal Adenocarcinoma

for Colorectal Adenocarcinoma Metastatic in the Liver

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT07082439·Phase 2·Recruiting

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Comparing Antibiotic Treatment Strategies for Children With Pneumonia in Outpatient Settings: (STAMPP)

for Community Acquired Pneumonia (CAP)

4 locations incl. Atlanta

Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All·Age: 12 Months - 71 Months

Code: NCT06986148·Recruiting

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Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

for Metastatic Clear Cell Renal Cell Carcinoma

Drug: Cabozantinib

40 locations incl. Gilbert

Sponsor: Arcus Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT07011719·Phase 3·Recruiting

Apply to this trial