Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,650 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 8, 2026.

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3,650 clinical trials

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Validation of Donor-Derived Cell-Free DNA (Dd-cfDNA) for Kidney Transplant Monitoring

for Kidney Transplant Rejection

8 locations incl. Los Angeles

Sponsor: Insight Molecular Diagnostics

Sex: All·Age: 18+

Code: NCT07060716·Recruiting

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Neoadjuvant Tebentafusp for Uveal Melanoma

for Locally Advanced Unresectable Uveal Melanoma

Drug: Tebentafusp

2 locations incl. Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT06414590·Phase 2·Recruiting

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Enhancing the Organizational Social Context to Improve Viral Suppression and Retention in HIV Care

for HIV/AIDS

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06462807·Recruiting

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Vape Use Among Younger & Older Smokers

for Smoking Cigarette

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 21 - 65

Code: NCT07214168·Recruiting

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A Study to Evaluate the Safety and Efficacy of BGB-16673 Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

for Chronic Lymphocytic Leukemia

36 locations incl. Phoenix

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06973187·Phase 3·Recruiting

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Endoscopic Ultrasound Shear Wave Elastography Study

for MASLD

2 locations incl. Boston

Sponsor: Olympus Corporation of the Americas

Sex: All·Age: 18+

Code: NCT06592820·Recruiting

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SMART Implementation-Effectiveness Trial 1

for Asthma in Children

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 5 - 18

Code: NCT07137923·Recruiting

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SMART Implementation-Effectiveness Trial 2

for Asthma in Children

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 5 - 18

Code: NCT07138027·Recruiting

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Post-Approval Study of the Neuspera Sacral Neuromodulation System

for Urinary Urgency Incontinence

20 locations incl. San Diego

Sponsor: Neuspera Medical, Inc.

Sex: All·Age: 22+

Code: NCT07144813·Recruiting

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A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease

for Colorectal Cancer

22 locations incl. Huntsville

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07023289·Phase 2·Recruiting

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Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)

for Elevated Lp(a)

Drug: Muvalaplin

121 locations incl. Gilbert

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07157774·Phase 3·Recruiting

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A Study of Pasritamig Versus Placebo in Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)

for Metastatic Castration-resistant Prostate Neoplasms

Drug: Pasritamig

50 locations incl. La Jolla

Sponsor: Janssen Research & Development, LLC

Sex: Male·Age: 18+

Code: NCT07164443·Phase 3·Recruiting

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Implementation of eHealth Delivery Alternatives for Cancer Genetic Testing for Hereditary Cancer (eREACH3)

for Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07471958·Recruiting

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Prospective Validation of the Novel PVD-B65 Risk Score in Patients With Chronic Lung Disease and Pulmonary Hypertension

for Chronic Lung Disease

1 location in Philadelphia

Sponsor: Temple University

Sex: All·Age: 18 - 99

Code: NCT07151768·Recruiting

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Dyed vs. Undyed Polyglactin Sutures in Cutaneous Surgery

for Wound Closure

1 location in Waynesburg

Sponsor: West Virginia University

Sex: All·Age: 18+

Code: NCT07078669·Enrolling By Invitation

Evaluating Patient Reported Outcomes and Surgeon Satisfaction With Ziplyft™

for Blepharoplasty

5 locations incl. Miami

Sponsor: Osheru Inc.

Sex: All·Age: 35+

Code: NCT07144761·Recruiting

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The Objective of the Protocol is to Generate Real World Evidence (RWE) Supporting the Safety, Performance, and Health Economics of Using the Regulatory Approved and Commercially Available EARP Interbody System Used During Lumbar Interbody Fusion (LIF) Procedures With the EARP Nerve Cuff Electrode

for Transforaminal Lumbar Interbody Fusion Surgery

3 locations incl. Sleepy Hollow

Sponsor: Retropsoas Technologies, LLC

Sex: All·Age: 22 - 80

Code: NCT07020000·Not Yet Recruiting

STOP-HAE: A Phase 3 Study of ADX-324 in HAE

for Hereditary Angioedema

15 locations incl. Litchfield Park

Sponsor: ADARx Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06960213·Phase 3·Recruiting

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Technology Assisted Collaborative Care Intervention to Improve Patient-centered Outcomes in Dialysis Patients

for Chronic Kidney Disease Requiring Hemodialysis

2 locations incl. Albuquerque

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06978127·Recruiting

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Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1

for Neurofibromatosis 1

Drug: Selumetinib

15 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 1 - 8

Code: NCT06188741·Phase 2·Recruiting

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Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

for Solid Tumor Malignancies

13 locations incl. Denver

Sponsor: Tasca Therapeutics

Sex: All·Age: 18+

Code: NCT07030257·Phase 1, Phase 2·Recruiting

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A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

for Advanced Pancreatic Carcinoma

109 locations incl. Birmingham

Sponsor: Sameek Roychowdhury

Sex: All·Age: 18+

Code: NCT06906562·Phase 2·Recruiting

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Penile Lengthening Pre-Penile Prosthesis Implantation

for Erectile Dysfunction

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Male·Age: 18+

Code: NCT07053826·Recruiting

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Post-cesarean Analgesia: Comparing Effectiveness of Staggered v. Simultaneous Therapies

for Cesarean Delivery

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: Female·Age: 16+

Code: NCT07102641·Phase 4·Recruiting

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855303-RNA Biomarker Validation

for Fractures, Bone

7 locations incl. Sacramento

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06872775·Enrolling By Invitation

Virtual Mindful After Cancer (MAC) Intervention to Promote Sexual Health for Breast and Gynecologic Cancer Survivors

for Gynecologic Cancers

3 locations incl. Corvallis

Sponsor: Oregon State University

Sex: Female·Age: 18+

Code: NCT07055854·Phase 1·Recruiting

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"Opt-In" Early Intervention Program for Children Waiting to Receive an Autism Diagnosis

for Autism

1 location in Philadelphia

Sponsor: Drexel University

Sex: All·Age: 16 Months - 48 Months

Code: NCT07081724·Recruiting

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A Phase 2 Study of Budoprutug in Subjects With Primary Membranous Nephropathy

for Primary Membranous Nephropathy

8 locations incl. Denver

Sponsor: Climb Bio, Inc.

Sex: All·Age: 18 - 75

Code: NCT07096843·Phase 2·Recruiting

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SLV-324 Treatment of Metastatic Solid Tumors

for Metastatic Solid Tumors

7 locations incl. Newport Beach

Sponsor: Solve Therapeutics

Sex: All·Age: 18+

Code: NCT07108114·Phase 1·Recruiting

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BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies

for Healthy

96 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 1 Day - 49·Accepts healthy volunteers

Code: NCT07160244·Phase 3·Recruiting

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Telerehabilitation In The Home After Stroke

for Stroke

27 locations incl. Downey

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 80

Code: NCT06682429·Recruiting

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A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors

for Urothelial Carcinoma Bladder

9 locations incl. Duarte

Sponsor: Aktis Oncology, Inc.

Sex: All·Age: 18+

Code: NCT07020117·Phase 1·Recruiting

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OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

for Cardiovascular Disease

Drug: Olpasiran

204 locations incl. Alexander City

Sponsor: Amgen

Sex: All·Age: 50 - 105

Code: NCT07136012·Phase 3·Recruiting

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Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

for Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma

279 locations incl. Gilbert

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06958328·Phase 3·Recruiting

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AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions

for Coronary Arterial Disease (CAD)

42 locations incl. La Jolla

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT06959524·Recruiting

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A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Episodic Migraine

for Episodic Migraine

Drug: Xeomin

46 locations incl. Chandler

Sponsor: Merz Therapeutics GmbH

Sex: All·Age: 18+

Code: NCT07018700·Phase 3·Recruiting

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A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic Migraine

for Chronic Migraine

Drug: Xeomin

46 locations incl. Chandler

Sponsor: Merz Therapeutics GmbH

Sex: All·Age: 18+

Code: NCT07018713·Phase 3·Recruiting

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Adaptive Radiation for Locally Advanced Unresectable Pancreatic Cancer

for Locally Advanced Pancreatic Ductal Adenocarcinoma (PDA)

1 location in Philadelphia

Sponsor: Fox Chase Cancer Center

Sex: All·Age: 18+

Code: NCT06984562·Recruiting

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Autobiographical Memory in Opioid Use Disorder

for Opioid Use Disorder

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06643988·Recruiting

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Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity

for Gastric Adenocarcinoma

55 locations incl. Irvine

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT07001748·Phase 2, Phase 3·Recruiting

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