Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,650 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 8, 2026.

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3,650 clinical trials

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Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

for Acute Leukemia of Ambiguous Lineage

Drug: Venetoclax

110 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 365 Days

Code: NCT06317662·Phase 2·Recruiting

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MOVE-HF MOtivating Physical Activity With BehaVioral Economics in Heart Failure With Preserved Ejection Fraction

for HFpEF - Heart Failure With Preserved Ejection Fraction

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06670001·Recruiting

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A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity

for Multiple Sclerosis Spasticity

15 locations incl. Birmingham

Sponsor: Celgene

Sex: All·Age: 18 - 70

Code: NCT06782490·Phase 2·Recruiting

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Effect of Inhaled Technosphere Insulin vs RAA Insulin on Exercise-Induced Hypoglycemia in Adults With T1D Using Automated Insulin Delivery

for Diabetes Mellitus, Type 1

3 locations incl. Louisville

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 18 - 65

Code: NCT06880835·Recruiting

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High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer

for Head and Neck Squamous Cell Carcinoma

200 locations incl. Gilbert

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06992427·Phase 3·Recruiting

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Prospective External Control Cohort In Patients With Newly Diagnosed Advanced or Metastatic EGFR Mutant Non-Small Cell Lung Cancer

for Non Small Cell Lung Cancer

6 locations incl. Monterey

Sponsor: N-Power Medicine

Sex: All·Age: 18+

Code: NCT07028489·Recruiting

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A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

for Leukemia, Myeloid, Acute

Drug: Venetoclax

50 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06852222·Phase 3·Recruiting

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Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION)

for Leber Congenital Amaurosis 10

5 locations incl. San Francisco

Sponsor: Laboratoires Thea

Sex: All·Age: 6+

Code: NCT06891443·Phase 3·Recruiting

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A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

for Cardiovascular Disease

315 locations incl. Athens

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07000357·Phase 3·Recruiting

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AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

for Solid Tumor Cancer

18 locations incl. Gilbert

Sponsor: Avenzo Therapeutics, Inc.

Sex: All·Age: 18 - 75

Code: NCT07038343·Phase 1, Phase 2·Recruiting

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Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

for Non-Muscle Invasive Bladder Urothelial Carcinoma

129 locations incl. Fayetteville

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06770582·Phase 2·Recruiting

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CTICU Device Study CRUISE

for Open Heart Surgery

1 location in Pittsburgh

Sponsor: Hernando Gomez

Sex: All·Age: 18 - 105

Code: NCT06828432·Enrolling By Invitation

A Study to Investigate Efficacy and Safety of SAR442970 in Patients With Crohn's Disease

for Crohn's Disease

20 locations incl. Tucson

Sponsor: Sanofi

Sex: All·Age: 18 - 75

Code: NCT06958536·Phase 2·Recruiting

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Depemokimab Asthma Imaging and Bronchoscopy Sub-Study

for Asthma

Drug: Depemokimab

9 locations incl. Brooksville

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06979323·Phase 3·Recruiting

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Home Blood Transfusions

for Hematologic Malignancy

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07121140·Recruiting

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Developing a Nonpharmacological Pain Intervention for Community-dwelling Older Adults With Dementia

for Pain, Chronic

1 location in Philadelphia

Sponsor: Drexel University

Sex: All·Age: 60+

Code: NCT06264362·Not Yet Recruiting

Vancomycin Reduction Practices (VRP) in the NICU

for Antibiotic Stewardship

13 locations incl. Modesto

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 18+

Code: NCT06772675·Recruiting

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Improving Prosthetic Arms for Amputee: A Better Fit and More Functionality

for Amputation, Surgical

1 location in Pittsburgh

Sponsor: VA Office of Research and Development

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT05990062·Recruiting

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Clinical Study of the inQB8 TTVR System (The MonarQ Study)

for Tricuspid Valve Regurgitation

6 locations incl. Los Angeles

Sponsor: inQB8 Medical Technologies, LLC

Sex: All·Age: 18+

Code: NCT06611579·Recruiting

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Silver Nitrate vs. Triamcinolone for Treatment of Hypergranulation Tissue

for Wound Healing

1 location in Pittsburgh

Sponsor: Francesco Egro

Sex: All·Age: 18+

Code: NCT06681194·Phase 2, Phase 3·Not Yet Recruiting

Concomitant LAAC/AF Ablation (Watchman FLX Pro)

for PFA Ablation and LAAC Procedures

11 locations incl. Birmingham

Sponsor: Heart Rhythm Clinical and Research Solutions, LLC

Sex: All·Age: 18+

Code: NCT07041125·Recruiting

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Inhaled Insulin vs Rapid-acting Injections for Post-meal Glucose Control in Women With Gestational Diabetes

for Diabetes, Gestational

5 locations incl. Santa Barbara

Sponsor: Jaeb Center for Health Research

Sex: Female·Age: 18 - 40

Code: NCT06535789·Phase 2, Phase 3·Recruiting

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A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

for B Acute Lymphoblastic Leukemia

137 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 366 Days - 46

Code: NCT06124157·Phase 2·Recruiting

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Testing Gene PilotLX With Latinx Cancer Patients

for Cancer

4 locations incl. Camden

Sponsor: Fox Chase Cancer Center

Sex: All·Age: 18 - 80

Code: NCT06476938·Recruiting

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Real-World Data Collection of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis When Used in Covered Endovascular Reconstruction of the Aortic Bifurcation (CERAB) to Treat Aortoiliac Occlusive Disease

for Aortoiliac Occlusive Disease

19 locations incl. Fresno

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18 - 100

Code: NCT06872905·Recruiting

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NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

for Major Depressive Disorder

Drug: NBI-1065845

14 locations incl. Chino

Sponsor: Neurocrine Biosciences

Sex: All·Age: 18+

Code: NCT06963021·Phase 3·Recruiting

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A Study of SYNC-T Therapy SV-102 in Participants With Metastatic Castration-Resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

19 locations incl. Phoenix

Sponsor: Syncromune, Inc.

Sex: Male·Age: 18+

Code: NCT06533644·Phase 2·Recruiting

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Pioglitazone Versus Empagliflozin for Chronic Pancreatitis/Recurrent Acute Pancreatitis Associated Diabetes Mellitus

for Pancreatitis, Chronic

Drug: Empagliflozin

2 locations incl. Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 80

Code: NCT06729996·Phase 2·Recruiting

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CMSL Ambulatory Sensitive Condition Nudge Study 2

for Behavioral Intervention

1 location in Danville

Sponsor: Geisinger Clinic

Sex: All·Age: 30+

Code: NCT07028398·Recruiting

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A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back Pain

for Obesity

Drug: Retatrutide

25 locations incl. Chandler

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07035093·Phase 3·Recruiting

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Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

for Prostate Cancer (Adenocarcinoma)

322 locations incl. Anchorage

Sponsor: Canadian Cancer Trials Group

Sex: Male·Age: 18+

Code: NCT06592924·Phase 3·Recruiting

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A Study to Assess Adverse Events and Change in Disease Activity in Participants With Platinum-Resistant Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha Expression Treated With Intravenously (IV) Infused Mirvetuximab Soravtansine

for Advanced High-Grade Epithelial Ovarian Cancer

7 locations incl. Sarasota

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT06682988·Phase 2·Recruiting

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Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

for Ovarian Cancer

21 locations incl. Birmingham

Sponsor: Regeneron Pharmaceuticals

Sex: Female·Age: 18+

Code: NCT06787612·Phase 2·Recruiting

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STimulation to Activate RespIration

for ARDS (Moderate or Severe)

5 locations incl. La Jolla

Sponsor: Lungpacer Medical Inc.

Sex: All·Age: 18+

Code: NCT06832306·Recruiting

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Study of BLU-808 in Chronic Inducible Urticaria (CIndU) and Chronic Spontaneous Urticaria (CSU)

for Chronic Inducible Urticaria

27 locations incl. Birmingham

Sponsor: Blueprint Medicines Corporation

Sex: All·Age: 18+

Code: NCT06931405·Phase 2·Recruiting

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Imaging Speech in Neurotypical Adults and Individuals With Cerebellar Stroke

for Stroke

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06458153·Recruiting

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CGM for the Early Detection and Management of Hyperglycemia in Pregnancy

for Gestational Diabetes Mellitus in Pregnancy

8 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06957028·Recruiting

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A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)

for Malignant Neoplasm

17 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 1 Month - 17

Code: NCT06941272·Phase 1, Phase 2·Recruiting

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Virtual Histology of the Bladder Wall for Bladder Cancer Staging

for Urinary Bladder Neoplasms

1 location in Pittsburgh

Sponsor: Jodi Maranchie

Sex: All·Age: 18 - 90

Code: NCT04369560·EARLY_Phase 1·Recruiting

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Small Cell Lung Cancer Community Engagement to Eliminate Research Discepancies

for Small-cell Lung Cancer

52 locations incl. Multiple Locations

Sponsor: Addario Lung Cancer Medical Institute

Sex: All·Age: 18+

Code: NCT06486428·Recruiting

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