Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,654 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 9, 2026.

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3,654 clinical trials

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A Study to Investigate the Long-term Safety and Efficacy of Belimumab in Adults With Interstitial Lung Disease (ILD) Associated With Systemic Sclerosis (SSc) and Other Connective Tissue Diseases (CTD) (BLISSconneCTD-OLE)

for Connective Tissue Diseases

1 location in Philadelphia

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06716606·Phase 3·Recruiting

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A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

for Colorectal Neoplasms

Drug: Amivantamab

70 locations incl. Chandler

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06750094·Phase 3·Recruiting

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Imaging Assessments of ARPKD Kidney Disease Progression

for Autosomal Recessive Polycystic Kidney Disease

2 locations incl. Cleveland

Sponsor: The Cleveland Clinic

Sex: All·Age: 6+·Accepts healthy volunteers

Code: NCT07201025·Recruiting

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A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis.

for Candidemia

23 locations incl. Birmingham

Sponsor: Basilea Pharmaceutica

Sex: All·Age: 18+

Code: NCT05421858·Phase 3·Recruiting

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Centering Gender Affirming Resources in Higher Education

for Sexual Violence

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06390332·Recruiting

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A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis

for Moderately to Severely Active Ulcerative Colitis

Drug: Afimkibart

71 locations incl. Dothan

Sponsor: Hoffmann-La Roche

Sex: All·Age: 16 - 80

Code: NCT06588855·Phase 3·Recruiting

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Study to Evaluate Ultevursen in Subjects With Retinitis Pigmentosa (RP) Due to Mutations in Exon 13 of the USH2A Gene

for Retinitis Pigmentosa (RP)

11 locations incl. San Francisco

Sponsor: Laboratoires Thea

Sex: All·Age: 8+

Code: NCT06627179·Phase 2·Recruiting

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Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer

for Resectable Lung Non-Small Cell Carcinoma

378 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06632327·Phase 3·Recruiting

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Support for Transgender and Non-Binary Individuals Seeking Vaginoplasty Study

for Gender Affirmation Surgery

9 locations incl. San Francisco

Sponsor: Oregon Health and Science University

Sex: Male·Age: 18+

Code: NCT06436560·Enrolling By Invitation

A Study to Investigate Efficacy and Safety of SAR441566 in Patients With Crohn's Disease.

for Crohn's Disease

19 locations incl. Sun City

Sponsor: Sanofi

Sex: All·Age: 18 - 75

Code: NCT06637631·Phase 2·Recruiting

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Detecting Change in Muscle Parameters, Pain, and Function With NMES for TTA

for Amputation

1 location in Pittsburgh

Sponsor: Sara Peterson-Snyder

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT06830876·Recruiting

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A Study to Evaluate the Efficacy and Safety of Autogene Cevumeran With Nivolumab Versus Nivolumab Alone in Participants With High-risk Muscle-invasive Urothelial Carcinoma (MIUC)

for Muscle-invasive Urothelial Carcinoma

Drug: Nivolumab

26 locations incl. Springdale

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06534983·Phase 2·Recruiting

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A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease

for COVID-19 SARS-CoV-2 Infection

84 locations incl. Little Rock

Sponsor: Pfizer

Sex: All·Age: 12+

Code: NCT06679140·Phase 3·Recruiting

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Post Marketing Study of MagnetOs Easypack Putty Standalone Compared to Demineralized Bone Matrix or Fibers Mixed With Autograft in Patients Undergoing Posterolateral Lumbar Fusion

for Degenerative Disc Disease

6 locations incl. Irvine

Sponsor: Kuros Biosurgery AG

Sex: All·Age: 18+

Code: NCT04679844·Recruiting

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Tipifarnib and Naxitamab for Relapsed/Refractory Neuroblastoma

for Neuroblastoma

12 locations incl. Little Rock

Sponsor: Giselle Sholler

Sex: All·Age: 1 - 21

Code: NCT06540963·Phase 2·Recruiting

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The Social Determinants of Health Screening and Referral Project

for Preterm Birth

7 locations incl. Denver

Sponsor: University of Massachusetts, Worcester

Sex: Female·Age: 18+

Code: NCT06582147·Enrolling By Invitation

A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)

for Carcinoma, Non-Small-Cell Lung

16 locations incl. Farmington

Sponsor: Johnson & Johnson Enterprise Innovation Inc.

Sex: All·Age: 18+

Code: NCT06667908·Phase 2·Recruiting

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Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot and Venous Leg Ulcers.

for Venous Leg Ulcer

1 location in Monroeville

Sponsor: Tiger Biosciences, LLC.

Sex: All·Age: 21+

Code: NCT06826339·Phase 4·Recruiting

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A Prospective, US-based Study Assessing Mogamulizumab-associated Rash in Patients Diagnosed With Mycosis Fungoides or Sezary Syndrome and Treated With Standard of Care Mogamulizumab

for Recurrent Mycosis Fungoides

10 locations incl. Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07003100·Recruiting

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A Study to Document and to Further Describe Long-term Safety and Effectiveness of Palovarotene in Participants With Fibrodysplasia Ossificans Progressiva (FOP)

for Fibrodysplasia Ossificans Progressiva

2 locations incl. San Francisco

Sponsor: Ipsen

Sex: All·Age: 8+

Code: NCT06089616·Recruiting

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Vagal Stimulator to Reduce Nasogastric Tube Use

for Nasogastric Tube Intubation

1 location in Pittsburgh

Sponsor: Jacques E. Chelly

Sex: All·Age: 18+

Code: NCT06648759·Recruiting

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Dilated Cardiomyopathy Detection Using AI and Screening With Mobile Technology (DCM-DETECT)

for Dilated Cardiomyopathy

1 location in Lancaster

Sponsor: Lancaster General Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06688396·Recruiting

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Feasibility of Resting Intervals During Exercise Programs for Individuals With Knee Osteoarthritis

for Knee Osteoarthristis

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 45 - 79

Code: NCT06857123·Recruiting

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A Study to Evaluate the Impact of Upadacitinib on Spondyloarthritis Outcomes in Patients With Active Psoriatic Arthritis

for Psoriatic Arthritis

Drug: Upadacitinib

3 locations incl. Cleveland

Sponsor: CARE ARTHRITIS LTD.

Sex: All·Age: 18+

Code: NCT06454188·Phase 4·Recruiting

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Dose-Response to Resistance Exercise on Cardiovascular Health

for Cardiovascular Risk

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 40+

Code: NCT06619444·Recruiting

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OurSleepKit To Support CPAP Adherence

for Obstructive Sleep Apnea

2 locations incl. Boston

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 18+

Code: NCT06621511·Recruiting

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A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

for Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

24 locations incl. Phoenix

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06679946·Phase 3·Enrolling By Invitation

Impact of Obicetrapib and Obicetrapib Plus Repatha on Lp(a) Levels

for Dyslipidemias

Drug: Obicetrapib

1 location in Philadelphia

Sponsor: NewAmsterdam Pharma

Sex: All·Age: 18 - 75

Code: NCT06496243·Phase 2·Recruiting

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A Study to Evaluate the Effectiveness of Long-acting (LA) Cabotegravir (CAB) + Rilpivirine (RPV) LA When Given to Participants With Detectable HIV-1

for HIV Infections

41 locations incl. Birmingham

Sponsor: ViiV Healthcare

Sex: All·Age: 12+

Code: NCT06694805·Phase 3·Recruiting

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Assessing Perceptions of ML Explanations by Medical Oncologists

for Oncology

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: All ages

Code: NCT06699615·Enrolling By Invitation

Meditation Effects on Discomfort, Pain InTerference, and AnxieTy After urEteroscopy

for Kidney Stone

2 locations incl. Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 12+·Accepts healthy volunteers

Code: NCT06783946·Enrolling By Invitation

A Study of RSLV-132 in Females With Sjögren's Disease

for Primary Sjögren Syndrome

24 locations incl. Chula Vista

Sponsor: Resolve Therapeutics

Sex: Female·Age: 18 - 75

Code: NCT06440525·Phase 2·Recruiting

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Streamlined Treatment of Pulmonary Exacerbations in Pediatrics

for Cystic Fibrosis

31 locations incl. Birmingham

Sponsor: University of Washington, the Collaborative Health Studies Coordinating Center

Sex: All·Age: 3 - 18

Code: NCT06654752·Recruiting

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Implementation of Red Blood Cell Transfusion Recommendations in the Pediatric Intensive Care Unit

for Red Blood Cell Transfusions

2 locations incl. Palo Alto

Sponsor: Stanford University

Sex: All·Age: All ages

Code: NCT07108374·Enrolling By Invitation

Testing the Addition of Immunotherapy Before Surgery for Patients With Sarcomatoid Mesothelioma

for Pleural Biphasic Mesothelioma

132 locations incl. Anchorage

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05647265·Phase 2·Recruiting

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CoMind Early Feasibility Study

for Intracranial Pressure

14 locations incl. Sacramento

Sponsor: CoMind Technologies Limited

Sex: All·Age: 18+

Code: NCT06368648·Recruiting

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Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body

for Castration-Resistant Prostate Carcinoma

174 locations incl. Fayetteville

Sponsor: SWOG Cancer Research Network

Sex: Male·Age: 18+

Code: NCT06470243·Phase 3·Recruiting

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Surovatamig (AZD0486) as Monotherapy in Participants With Relapsed/Refractory (R/R) B-cell NHL

for B-cell Non-Hodgkin Lymphoma

23 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06526793·Phase 2·Recruiting

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A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Metastatic Non-squamous NSCLC

for Non-squamous Non-small Cell Lung Cancer

Drug: Rilvegostomig

77 locations incl. Mobile

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06627647·Phase 3·Recruiting

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A Study to Investigate Safety and Effectiveness of BGB-16673 in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies

for B-cell Malignancy

18 locations incl. Phoenix

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06634589·Phase 1, Phase 2·Recruiting

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