Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,479 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 4, 2026.

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3,012 clinical trials

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Subcortical Arousal in Perceptual Awareness

for Epilepsy

Sites in Pittsburgh +7 more locations

Sponsor: Yale University

Sex: All·Age: 13+

Code: NCT06934356·Recruiting·Listed Apr 2025

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Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

for Metastatic Colorectal Carcinoma

Sites in Philadelphia, Pittsburgh +52 more locations

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT05863195·Phase 3·Recruiting·Listed May 2023

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Functional Assessment in Liver Transplantation

for End Stage Liver Disease

Sites in Pittsburgh +7 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT03228290·Recruiting·Listed Jul 2017

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A RCT of Spectacles With Aspherical Lenslets or 0.05% Atropine for Myopia Control

for Myopia

Sites in Philadelphia +16 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 5 - 11

Code: NCT07095894·Phase 3·Recruiting·Listed Jul 2025

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Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis

for Systemic Sclerosis

3 locations in Pittsburgh

Sponsor: Paul Szabolcs

Sex: All·Age: 8 - 60

Code: NCT03630211·Phase 2·Recruiting·Listed Aug 2018

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Cortical Excitability in Cyclic Vomiting Syndrome

for Cyclic Vomiting Syndrome

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT05256160·Recruiting·Listed Feb 2022

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Inflammatory Bowel Disease (IBD) Research Registry

for Inflamatory Bowel Disease (Crohn's and Ulcerative Colitis)

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT04243525·Recruiting·Listed Jan 2020

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Cord Clamping Among Neonates With Congenital Heart Disease

for Congenital Heart Disease (CHD)

Sites in Philadelphia +17 more locations

Sponsor: Carl Backes, MD

Sex: All·Age: 37 Weeks - 42 Weeks

Code: NCT06153459·Recruiting·Listed Dec 2023

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Using the EHR to Advance Genomic Medicine Across a Diverse Health System

for Genetic Predisposition

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06377033·Recruiting·Listed Apr 2024

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Interferon-γ (IFN-γ) With Donor Leukocyte Infusion to Treat Relapsed Acute Myeloid Leukemia and Myelodysplastic Syndromes Post Allogeneic Hematopoietic Stem Cell Transplantation

for Acute Myeloid Leukemia

Sites in Pittsburgh +2 more locations

Sponsor: Sawa Ito, MD

Sex: All·Age: 18+

Code: NCT06529731·Phase 2·Recruiting·Listed Jul 2024

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Individualized Treatment Plan in Children and Young Adults With Relapsed Medulloblastoma and Ependymoma

for Medulloblastoma

Sites in Philadelphia +8 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 12 Months - 39

Code: NCT05057702·Recruiting·Listed Sep 2021

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Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight

for 16P11.2 Deletion Syndrome

Sites in Lewisburg +1 more location

Sponsor: Simons Searchlight

Sex: All·Age: All ages

Code: NCT01238250·Recruiting·Listed Nov 2010

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Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants

for Inherited Retinal Degeneration

Sites in Philadelphia, Pittsburgh +17 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 4+

Code: NCT05589714·Recruiting·Listed Oct 2022

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From Screening to Support: A Multi-Method Analysis of HRSN Integration in Cancer Care

for Cancer

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07352579·Recruiting·Listed Jan 2026

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Belumosudil to Block Chronic Lung Allograft Dysfunction (CLAD) in High Risk Lung Transplant Recipients

for Lung Transplant

Sites in Philadelphia +10 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 12+

Code: NCT06476132·Phase 2·Recruiting·Listed Jun 2024

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Fast In-Bed Tracking (FIT) System Lifestyle Intervention is a Clinical Trial of a Bed Scale Device. Overweight Wheelchair Users Will Complete a Weight Loss Program, Half Get Scales at Baseline, Half at Month 6 Those Who Receive the Bed Scales at Baseline Are Expected to Have Increased Weight Loss

for Disability Physical

1 location in Pittsburgh

Sponsor: Jonathan Pearlman

Sex: All·Age: 18+

Code: NCT07141342·Recruiting·Listed Aug 2025

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Tocilizumab Discontinuation Versus Dose Reduction for Patients With Well-Controlled Giant Cell Arteritis

for Giant Cell Arteritis (GCA)

Drug: Tocilizumab

Sites in Pittsburgh +6 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 50+

Code: NCT07108387·Phase 2·Recruiting·Listed Aug 2025

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Testing the Addition of Abemaciclib to Olaparib for Women With Recurrent Ovarian Cancer

for Recurrent Ovarian High Grade Serous Adenocarcinoma

Sites in Philadelphia +11 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT04633239·Phase 1·Recruiting·Listed Nov 2020

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De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

for Stage I Breast Cancer

Sites in Philadelphia, Pittsburgh +705 more locations

Sponsor: NRG Oncology

Sex: All·Age: 50 - 70

Code: NCT04852887·Phase 3·Recruiting·Listed Apr 2021

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Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Drug: Tremelimumab

Sites in Pittsburgh +22 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03606967·Phase 2·Recruiting·Listed Jul 2018

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Testing the Safety of Anti-Cancer Drug, CX-5461 (Pidnarulex), in Treating Lymphoma With Specific Changes in the MYC Gene

for Burkitt Lymphoma

Drug: Pidnarulex

Sites in Pittsburgh +7 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07069699·Phase 1, Phase 2·Recruiting·Listed Jul 2025

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Observational Study of Women With Endometrial Cancer Who Receive the Standard Treatment for Their Disease

for Endometrial Cancer

Sites in Allentown +11 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female·Age: 18+

Code: NCT04291612·Recruiting·Listed Mar 2020

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Penile Lengthening Pre-Penile Prosthesis Implantation

for Erectile Dysfunction

1 location in Pittsburgh

Sponsor: J. Peter Rubin, MD

Sex: Male·Age: 18+

Code: NCT07053826·Recruiting·Listed Jul 2025

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CAlcium and VAsopressin Following Injury Early Resuscitation (CAVALIER) Trial

for Trauma

Sites in Pittsburgh +15 more locations

Sponsor: Jason Sperry

Sex: All·Age: 18 - 90

Code: NCT05958342·Phase 2·Recruiting·Listed Jul 2023

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The Effects of Successful OSA Treatment on Memory and AD Biomarkers in Older Adults Study

for Obstructive Sleep Apnea

Sites in Pittsburgh +3 more locations

Sponsor: California Pacific Medical Center Research Institute

Sex: All·Age: 55 - 85

Code: NCT05988385·Recruiting·Listed Aug 2023

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Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes

for Lung Transplant

Sites in Philadelphia, Pittsburgh +16 more locations

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06399302·Recruiting·Listed May 2024

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The MIGHT Trial - An Exploratory Clinical Trial of IVIG in Anti-HMGCR Immune Mediated Necrotizing Myopathy

for Anti-3-hydroxy-3-methylglutaryl-CoA Reductase (HMGCR) Immune-Mediated Necrotizing Myopathy

Sites in Pittsburgh +3 more locations

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 16+

Code: NCT06599697·Phase 2·Recruiting·Listed Sep 2024

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Testing the Addition of an Anti-Cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (5-Fluorouracil) for Metastatic, Refractory Colorectal Cancer

for Metastatic Microsatellite Stable Colorectal Carcinoma

Sites in Pittsburgh +7 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06654037·Phase 1·Recruiting·Listed Oct 2024

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High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer

for Head and Neck Squamous Cell Carcinoma

Sites in Philadelphia, Pittsburgh +167 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06992427·Phase 3·Recruiting·Listed May 2025

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Transpyloric Versus Gastric Feeding in Bronchopulmonary Dysplasia

for Bronchopulmonary Dysplasia

Sites in Philadelphia +3 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 1 Month - 12 Months

Code: NCT06534359·Recruiting·Listed Aug 2024

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ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

for Diffuse Intrinsic Pontine Gliomas (DIPG)

Sites in Philidelphia +11 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 12 Months - 39

Code: NCT06838676·Phase 2·Recruiting·Listed Feb 2025

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Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus

for Type 1 Diabetes Mellitus

Sites in Pittsburgh +8 more locations

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 8 - 45

Code: NCT07142252·Phase 2·Recruiting·Listed Aug 2025

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Milrinone for Prevention of Post-ligation Cardiac Syndrome Trial

for Post-ligation Cardiac Syndrome

Sites in Philadelphia +18 more locations

Sponsor: NICHD Neonatal Research Network

Sex: All·Age: Up to 3 Months

Code: NCT06679855·Phase 3·Recruiting·Listed Nov 2024

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Follow-up Visit of High Risk Infants

for Infant, Newborn

Sites in Philadelphia +18 more locations

Sponsor: NICHD Neonatal Research Network

Sex: All·Age: 18 Months - 26 Months

Code: NCT00009633·Recruiting·Listed Feb 2001

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Distal Radius Interventions for Fracture Treatment

for Fracture Distal Radius

Sites in Philadelphia +23 more locations

Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All·Age: 4 - 10

Code: NCT05131685·Recruiting·Listed Nov 2021

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Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer

for Locoregional Recurrence

Drug: Ribociclib

Sites in Hershey +18 more locations

Sponsor: Oana Danciu

Sex: All·Age: 18+

Code: NCT05467891·Phase 2·Recruiting·Listed Jul 2022

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DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes

for Gestational Diabetes Mellitus

Sites in Philadelphia, Pittsburgh +19 more locations

Sponsor: Ohio State University

Sex: Female·Age: 18+

Code: NCT06445946·Phase 4·Recruiting·Listed Jun 2024

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Rett Syndrome Registry

for Rett Syndrome

Sites in Philadelphia +18 more locations

Sponsor: International Rett Syndrome Foundation

Sex: All·Age: 0 - 99

Code: NCT05432349·Recruiting·Listed Jun 2022

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Primary Sclerosing Cholangitis in Children

for Primary Sclerosing Cholangitis

Sites in Philadelphia +8 more locations

Sponsor: Arbor Research Collaborative for Health

Sex: All·Age: 2 - 25

Code: NCT04181138·Recruiting·Listed Nov 2019

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Molecular Genetics Studies of Cancer Patients and Their Relatives

for Malignant Neoplasm

Sites in West Reading, Paoli +33 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04185935·Recruiting·Listed Dec 2019

Apply to this trial