Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,654 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 9, 2026.

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3,654 clinical trials

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Evaluating Verbal Communication in Structured Interactions: Theoretical and Clinical Implications

for Amyotrophic Lateral Sclerosis

1 location in University Park

Sponsor: Penn State University

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT06266403·Recruiting

Apply to this trial

FIH Study to Evaluate the Tolerability of PF-07832837 in Healthy Adults and Patients

for Healthy Participants

Drug: PF-07832837

3 locations incl. Anaheim

Sponsor: Pfizer

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT06564389·Phase 1·Recruiting

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Targeted EHR-based Communication of Diagnostic Uncertainty in the ED

for Diagnostic Uncertainty

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT06638021·Recruiting

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PULSED AF Post-Approval Study

for Atrial Fibrillation

18 locations incl. Tampa

Sponsor: Medtronic Cardiac Ablation Solutions

Sex: All·Age: 18+

Code: NCT06578104·Recruiting

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Glycogen Storage Disease Type Ia (GSDIa) Disease Monitoring Program

for Glycogen Storage Disease Type Ia

9 locations incl. Orange

Sponsor: Ultragenyx Pharmaceutical Inc

Sex: All·Age: 2+

Code: NCT06636383·Recruiting

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Conduit Cages and Fibergraft BG Putty

for Degenerative Disc Disease

1 location in Pittsburgh

Sponsor: Nitin Agarwal

Sex: All·Age: 18+

Code: NCT06704919·Recruiting

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Massive Transfusion in Children-2: A Trial Examining Life Threatening Hemorrhage in Children

for Hemorrhagic Shock

23 locations incl. Tucson

Sponsor: Philip Spinella

Sex: All·Age: Up to 17

Code: NCT06070350·Phase 3·Recruiting

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Transition to Cardiac Rehabilitation (T2CR) to Address Barriers of Multimorbidity and Frailty

for Cardiovascular Diseases

2 locations incl. Boston

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT06244199·Recruiting

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Chronic Subdural Hematoma Treatment With Embolization Versus Surgery Study

for Chronic Subdural Hematoma

31 locations incl. Phoenix

Sponsor: The University of Texas Medical Branch, Galveston

Sex: All·Age: 40 - 90

Code: NCT06347796·Recruiting

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A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal Cancer

for Nasopharyngeal Cancer Recurrent

12 locations incl. Little Rock

Sponsor: Coherus Oncology, Inc.

Sex: All·Age: 12+

Code: NCT06457503·Phase 4·Recruiting

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SynKIR-310 for Relapsed/Refractory B-NHL

for B Cell Lymphoma

5 locations incl. Denver

Sponsor: Verismo Therapeutics

Sex: All·Age: 18+

Code: NCT06544265·Phase 1·Recruiting

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Environmental and Sensory Intervention for Nursing Home Residents With Dementia Who Exhibit Persistent Vocalizations

for Dementia

1 location in Philadelphia

Sponsor: Drexel University

Sex: All·Age: 50+

Code: NCT06568107·Recruiting

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Adult Trauma Centers RE-AIM at Gun Safety

for Firearm Injury

3 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06302452·Enrolling By Invitation

Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease

for Moderately to Severely Active Crohn Disease

43 locations incl. Fairhope

Sponsor: Abivax S.A.

Sex: All·Age: 18 - 75

Code: NCT06456593·Phase 2·Recruiting

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Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

for Neuroblastoma

20 locations incl. Birmingham

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: Up to 30

Code: NCT06541262·Phase 1, Phase 2·Recruiting

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A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy

for Age-related Macular Degeneration (AMD)

Drug: Cemdisiran

152 locations incl. West Jordan

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 50 - 85

Code: NCT06541704·Phase 3·Recruiting

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A Study to Investigate the Safety and Efficacy of SAR446523 Injected Subcutaneously in Adult Participants With Relapsed/Refractory Myeloma

for Plasma Cell Myeloma Refractory

5 locations incl. Phoenix

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06630806·Phase 1·Recruiting

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A Study of Valemetostat Tosylate Plus Pembrolizumab Versus Pembrolizumab Alone in First-Line NSCLC Without Actionable Genomic Alterations

for Non-small Cell Lung Cancer

12 locations incl. La Jolla

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06644768·Phase 1, Phase 2·Recruiting

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The THOR IDE Study

for Peripheral Artery Disease

29 locations incl. St. Helena

Sponsor: Philips Clinical & Medical Affairs Global

Sex: All·Age: 18+

Code: NCT05916950·Recruiting

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The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study

for Metastatic Breast Cancer

73 locations incl. Chandler

Sponsor: American Society of Clinical Oncology

Sex: All·Age: 65+

Code: NCT06377852·Phase 3·Recruiting

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A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Endometrial Cancer.

for Endometrial Cancer

Drug: Lifileucel

12 locations incl. Phoenix

Sponsor: Iovance Biotherapeutics, Inc.

Sex: Female·Age: 18 - 70

Code: NCT06481592·Phase 2·Recruiting

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Safety Study of SMOFlipid to Evaluate the Risk of Developing EFAD and/or PNAC in Pediatric and Adult Patients

for Malnutrition, Child

5 locations incl. Atlanta

Sponsor: Fresenius Kabi

Sex: All·Age: 1 Month - 17

Code: NCT06049680·Phase 4·Recruiting

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Apimostinel + Automated Neurocognitive Training for Depression

for Depression

1 location in Pittsburgh

Sponsor: Rebecca Price

Sex: All·Age: 18 - 60

Code: NCT06400121·Phase 2·Recruiting

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Bright Light Therapy for OSA

for Obstructive Sleep Apnea

1 location in Pittsburgh

Sponsor: VA Office of Research and Development

Sex: All·Age: 40 - 65

Code: NCT05917119·Recruiting

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Simvastatin Treatment to Improve Patient-reported Outcomes in Patients With Chronic Pancreatitis

for Recurrent Acute Pancreatitis

5 locations incl. Los Angeles

Sponsor: Cedars-Sinai Medical Center

Sex: All·Age: 18 - 75

Code: NCT05771675·EARLY_Phase 1·Recruiting

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A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

for Sickle Cell Disease

14 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 100

Code: NCT06439082·Phase 3·Recruiting

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A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)

for Healthy Volunteers, Pulmonary Arterial Hypertension

19 locations incl. Scottsdale

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT06649110·Phase 1, Phase 2·Recruiting

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Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma

for Classic Follicular Lymphoma

Drug: Mosunetuzumab

267 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06337318·Phase 3·Recruiting

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Blue Light as an Anti-inflammatory and Analgesic Strategy in Thoracic Trauma

for Rib Fractures

1 location in Pittsburgh

Sponsor: Rebecca E Kotcher, MD

Sex: All·Age: 18+

Code: NCT06626334·Recruiting

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Study to Evaluate Avacopan in Combination With a Rituximab or Cyclophosphamide-containing Regimen, in Children From 6 Years to < 18 Years of Age With AAV.

for Vasculitis

Drug: Rituximab

10 locations incl. Atlanta

Sponsor: Amgen

Sex: All·Age: 6 - 17

Code: NCT06321601·Phase 3·Recruiting

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A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

for Basal Ganglia Germinoma

92 locations incl. Mobile

Sponsor: Children's Oncology Group

Sex: All·Age: 3 - 29

Code: NCT06368817·Phase 2·Recruiting

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Sacral Neuromodulation for Male Overactive Bladder (MOAB)

for Overactive Bladder

20 locations incl. Birmingham

Sponsor: Axonics, Inc.

Sex: Male·Age: 18+

Code: NCT06511141·Recruiting

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Dichoptic Treatment for Amblyopia in Children 8 to 12 Years of Age

for Amblyopia

58 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 8 - 12

Code: NCT06524882·Phase 3·Recruiting

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Dyadic Sleep Study

for Gastrointestinal Cancer

2 locations incl. Coral Gables

Sponsor: University of Miami

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06569693·Recruiting

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ATTUNE: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION440 in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome (MDS)

for Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome

8 locations incl. San Diego

Sponsor: Ionis Pharmaceuticals, Inc.

Sex: Male·Age: 2 - 65

Code: NCT06430385·Phase 1, Phase 2·Recruiting

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Open-Label Extension Study of Setmelanotide

for Obesity Associated With Defects in Leptin-melanocortin Pathway

13 locations incl. Scottsdale

Sponsor: Rhythm Pharmaceuticals, Inc.

Sex: All·Age: 2+

Code: NCT06596135·Phase 3·Enrolling By Invitation

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

for Carcinoma, Non-Small-Cell Lung

Drug: Intismeran autogene

48 locations incl. Gilbert

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06623422·Phase 3·Recruiting

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Characterization and Natural History of Williams Syndrome and Other Chromosome 7q11.23 Variants

for Williams Beuren Syndrome

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06930417·Recruiting

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Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL

for Hypertensive Disorders of Pregnancy

16 locations incl. Birmingham

Sponsor: Ohio State University

Sex: Female·Age: 14 - 35

Code: NCT06468202·Phase 4·Recruiting

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A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

for Colorectal Neoplasms

Drug: Amivantamab

79 locations incl. Gilbert

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06662786·Phase 3·Recruiting

Apply to this trial