Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,479 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 4, 2026.

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3,012 clinical trials

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Letrozole in Uterine Leiomyosarcoma

for Uterine Leiomyosarcoma

Sites in Willow Grove +33 more locations

Sponsor: GOG Foundation

Sex: Female·Age: 18+

Code: NCT05649956·Phase 2·Recruiting·Listed Dec 2022

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Testing the Effectiveness of the Anti-cancer Drug, Mirdametinib, in Treating Relapsed, Refractory Chronic Lymphocytic Leukemia

for Recurrent Chronic Lymphocytic Leukemia

Drug: Mirdametinib

Sites in Pittsburgh +7 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07061951·Phase 2·Recruiting·Listed Jul 2025

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Multisite Inventory of Neonatal-Perinatal Interventions (MINI) Minimum Dataset

for Infant, Extremely Premature

Sites in Philadelphia +42 more locations

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 0 - 1

Code: NCT05685745·Recruiting·Listed Jan 2023

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Pioglitazone Versus Empagliflozin for Chronic Pancreatitis/Recurrent Acute Pancreatitis/Acute Pancreatitis Associated Diabetes Mellitus

for Pancreatitis, Chronic

Drug: Empagliflozin

Sites in Pittsburgh +2 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 80

Code: NCT06729996·Phase 2·Recruiting·Listed Dec 2024

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Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

Drug: Cemiplimab

Sites in Philadelphia, Pittsburgh +379 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06616584·Phase 2, Phase 3·Recruiting·Listed Sep 2024

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Dorzagliatin in Pancreatic Insufficient Cystic Fibrosis

for Pancreatic Insufficiency

2 locations in Philadelphia

Sponsor: Michael R. Rickels, MD, MS

Sex: All·Age: 18+

Code: NCT06995651·Phase 1·Recruiting·Listed May 2025

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Endometriosis and Microvascular Dysfunction: Role of Inflammation

for Endometriosis

1 location in University Park

Sponsor: Penn State University

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT05069740·EARLY_Phase 1·Recruiting·Listed Oct 2021

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Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

for Colorectal Carcinoma

Sites in Philadelphia, Pittsburgh +17 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 12 Months - 30

Code: NCT04851119·Phase 1, Phase 2·Recruiting·Listed Apr 2021

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Testing the Anti-cancer Drug, Glofitamab, in Patients With Mantle Cell Lymphoma (A Type of Blood Cancer) Whose Disease Returned After CAR-T Cell Therapy

for Recurrent Mantle Cell Lymphoma

Drug: Glofitamab

Sites in Pittsburgh +9 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07003295·Phase 2·Recruiting·Listed Jun 2025

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The Fourth Left Atrial Appendage Occlusion Study

for Atrial Fibrillation

Sites in Philadelphia, Pittsburgh +45 more locations

Sponsor: Hamilton Health Sciences Corporation

Sex: All·Age: 18+

Code: NCT05963698·Recruiting·Listed Jul 2023

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Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

for Locally Advanced Lung Non-Small Cell Carcinoma

Drug: Sotorasib

Sites in Pittsburgh +8 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07012031·Phase 1, Phase 2·Recruiting·Listed Jun 2025

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Expanding Liver Transplant Immunosuppression Minimization Via Everolimus

for Liver Transplant

Sites in Philadelphia, Pittsburgh +6 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+

Code: NCT06280950·Phase 2·Recruiting·Listed Feb 2024

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Technology Assisted Collaborative Care Intervention to Improve Patient-centered Outcomes in Dialysis Patients

for Chronic Kidney Disease Requiring Hemodialysis

Sites in Pittsburgh +1 more location

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06978127·Recruiting·Listed May 2025

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Pragmatic, Open-Label Study to Pilot Evaluation for Clinical Trials in Relapsing Polychondritis

for Relapsing Polychondritis

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06941376·Phase 2·Recruiting·Listed Apr 2025

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ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

for Hematologic Disorder

Sites in Philadelphia, Pittsburgh +74 more locations

Sponsor: American Thrombosis and Hemostasis Network

Sex: All·Age: All ages

Code: NCT04398628·Recruiting·Listed May 2020

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The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry

for Cesarean Delivery

Sites in Pittsburgh +32 more locations

Sponsor: Yale University

Sex: Female·Age: 15 - 55·Accepts healthy volunteers

Code: NCT06030063·Recruiting·Listed Sep 2023

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PEEL-224, Vincristine and Temozolomide in Pediatric Solid Tumors

for Refractory Solid Tumors

Sites in Philadelphia +6 more locations

Sponsor: Theodore Laetsch

Sex: All·Age: 1 - 30

Code: NCT06721689·Phase 1, Phase 2·Recruiting·Listed Dec 2024

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Pembrolizumab, Olaparib, and Temozolomide for People With Glioma

for Glioma

Sites in Allentown +9 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT05188508·Phase 2·Recruiting·Listed Jan 2022

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A Study to Find the Highest Dose of Cedazuridine and Decitabine Combination With Filgrastim as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With High-Risk Acute Myeloid Leukemia

for Acute Myeloid Leukemia Post Cytotoxic Therapy

Sites in Philadelphia, Pittsburgh +9 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 21

Code: NCT07012044·Phase 1·Recruiting·Listed Jun 2025

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Transoral Surgical Resection Followed by De-escalated Adjuvant IMRT in Resectable p16+ Locally Advanced Oropharynx Cancer

for Oropharynx Cancer

1 location in Pittsburgh

Sponsor: Heath Skinner

Sex: All·Age: 18+

Code: NCT05388773·Phase 2·Recruiting·Listed May 2022

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A Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal Mesothelioma

for Malignant Peritoneal Mesothelioma

Sites in Pittsburgh +12 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06057935·Phase 2·Recruiting·Listed Sep 2023

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Massive Transfusion in Children-2: A Trial Examining Life Threatening Hemorrhage in Children

for Hemorrhagic Shock

Sites in Pittsburgh +19 more locations

Sponsor: Philip Spinella

Sex: All·Age: Up to 17

Code: NCT06070350·Phase 3·Recruiting·Listed Oct 2023

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Remote Sputum Collection in Cystic Fibrosis

for Cystic Fibrosis

Sites in Philadelphia +3 more locations

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06950892·Recruiting·Listed Apr 2025

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Dental Implant Healing With TNF-Alpha Inhibitors

for Edentulism

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06538870·Recruiting·Listed Aug 2024

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Neurocognition in Congenital Central Hypoventilation Syndrome (CCHS)

for Congenital Central Hypoventilation Syndrome

Sites in Philadelphia +3 more locations

Sponsor: Ilya Khaytin

Sex: All·Age: 3 - 85

Code: NCT03568669·Recruiting·Listed Jun 2018

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Time Restricted Eating for the Improvement of Outcomes in Patients With Stage I-III Breast Cancer Receiving Chemotherapy Before Surgery

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Philadelphia, Willow Grove +3 more locations

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT05327608·Recruiting·Listed Apr 2022

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Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

for High Grade Glioma

Sites in Philadelphia +2 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 4 - 39

Code: NCT05278208·Phase 1, Phase 2·Recruiting·Listed Mar 2022

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Zinc Oxide Versus Petrolatum Following Skin Surgery

for Surgical Incision

1 location in Pittsburgh, PA

Sponsor: Melissa Pugliano-Mauro

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT03561376·EARLY_Phase 1·Recruiting·Listed Jun 2018

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SPENDD: Quantitative Sensory Testing and Analgesic Response for Painful Peripheral Neuropathy.

for Painful Peripheral Neuropathy

Sites in Pittsburgh +6 more locations

Sponsor: University of Rochester

Sex: All·Age: 18 - 80

Code: NCT06614322·Phase 2·Recruiting·Listed Sep 2024

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Speech Signals in Stuttering

for Stuttering, Childhood

Sites in Pittsburgh +1 more location

Sponsor: University of Pittsburgh

Sex: All·Age: 5 - 17·Accepts healthy volunteers

Code: NCT05668923·Recruiting·Listed Dec 2022

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Mobile Health Self-Management and Support System for Chronic and Complex Health Conditions

for Spinal Cord Injuries

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 12+·Accepts healthy volunteers

Code: NCT02592291·Recruiting·Listed Oct 2015

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Trial of Pre-operative Neratinib and Endocrine Therapy With Trastuzumab in ER-Positive, HER-2 Positive Breast Cancers

for Breast Cancer

Sites in Hershey +3 more locations

Sponsor: Ruth O'Regan

Sex: All·Age: 18+

Code: NCT04886531·Phase 2·Recruiting·Listed May 2021

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Decoding and Modulating Affective Brain States

for Rumination

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 65

Code: NCT05437705·Recruiting·Listed Jun 2022

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Patient Navigation Program to Improve Clinical Trial Enrollment in Cancer Patients

for Prostate Cancer

Sites in Chambersburg +1 more location

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT06138067·Recruiting·Listed Nov 2023

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Safety and Efficacy of AGN-INM176 in Prostate Patients With Rising PSA

for Prostate Cancer

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: Male·Age: 40+

Code: NCT06600698·Phase 1, Phase 2·Recruiting·Listed Sep 2024

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Genetic Polymorphisms in Idiopathic Pulmonary Fibrosis (IPF)

for Pulmonary Fibrosis

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT00258570·Recruiting·Listed Nov 2005

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Deep Brain Stimulation Effects In Patients With Opioid Use Disorder

for Opioid-use Disorder

1 location in Pittsburgh

Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sex: All·Age: 22 - 65

Code: NCT04354077·Recruiting·Listed Apr 2020

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ACDF Using Structural Allograft vs. Tritanium C

for Degenerative Disc Disease

1 location in Pittsburgh

Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sex: All·Age: 18 - 80

Code: NCT04388332·Recruiting·Listed May 2020

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Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

for Clinical Stage III Cutaneous Melanoma AJCC v8

Sites in Pittsburgh +24 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05896839·Phase 1, Phase 2·Recruiting·Listed Jun 2023

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Lurbinectedin in FET-Fused Tumors

for Ewing Sarcoma

Drug: Lurbinectedin

Sites in Philadelphia +5 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 10+

Code: NCT05918640·Phase 1, Phase 2·Recruiting·Listed Jun 2023

Apply to this trial