Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,654 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 9, 2026.

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3,654 clinical trials

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Diabetes RElated to Acute Pancreatitis and Its Mechanisms: Metabolic Outcomes Using Novel CGM Metrics

for Acute Pancreatitis

13 locations incl. Los Angeles

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 75

Code: NCT06401577·Recruiting

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Clinical Outcomes of Patients with LAL+ in At Least One Eye

for IOL, Cataract

1 location in Wilkes-Barre

Sponsor: Frank A. Bucci, Jr., M.D.

Sex: All·Age: All ages

Code: NCT06650358·Enrolling By Invitation

Enhancing Memory in CPT for PTSD

for Stress Disorders, Post-Traumatic

1 location in Philadelphia

Sponsor: VA Office of Research and Development

Sex: All·Age: 60+

Code: NCT06000475·Recruiting

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Criterion-learning Based Naming Treatment in Aphasia

for Aphasia

1 location in Elkins Park

Sponsor: Albert Einstein Healthcare Network

Sex: All·Age: 18 - 89

Code: NCT06364709·Enrolling By Invitation

A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study

for Hematopoietic and Lymphatic System Neoplasm

76 locations incl. Mesa

Sponsor: Children's Oncology Group

Sex: All·Age: 15 - 20

Code: NCT06410209·Phase 2·Recruiting

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Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response

for Arthritis, Psoriatic

44 locations incl. Avondale

Sponsor: MoonLake Immunotherapeutics AG

Sex: All·Age: 18+

Code: NCT06641089·Phase 3·Recruiting

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Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

for Liver Neoplasms

30 locations incl. Fullerton

Sponsor: HistoSonics, Inc.

Sex: All·Age: 22+

Code: NCT06486454·Recruiting

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Open-label Extension Study to Evaluate Metreleptin in Patients With Partial Lipodystrophy

for Familial Partial Lipodystrophy

7 locations incl. Birmingham

Sponsor: Amryt Pharma

Sex: All·Age: 13+

Code: NCT06679270·Phase 3·Recruiting

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A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia

for Leukemia, Juvenile Myelomonocytic

Drug: Trametinib

19 locations incl. Phoenix

Sponsor: Therapeutic Advances in Childhood Leukemia Consortium

Sex: All·Age: 1 Month - 21

Code: NCT05849662·Phase 1, Phase 2·Recruiting

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Beamion PANTUMOR-1: A Study to Test Whether Zongertinib Helps People With Advanced Cancers With HER2 Alterations

for Solid Tumours

20 locations incl. Anchorage

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06581432·Phase 2·Recruiting

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QuantifyHER: Quantitative Immunofluorescence and/or RT-qPCR for Measuring HER2 in HER2-low Metastatic Breast Cancer

for HER2-positive Metastatic Breast Cancer

37 locations incl. San Francisco

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT06551116·Recruiting

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A Study to Evaluate IPN10200 Safety and Efficacy in the Prevention of Episodic or Chronic Migraine in Adults

for Episodic Migraine

71 locations incl. Birmingham

Sponsor: Ipsen

Sex: All·Age: 18 - 80

Code: NCT06625060·Phase 2·Recruiting

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Need to be Needed (N2BN) Intervention

for Loneliness

1 location in Philadelphia

Sponsor: Temple University

Sex: All·Age: 18 - 99

Code: NCT06510439·Recruiting

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A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%

for Non-small Cell Lung Cancer

Drug: Relatlimab

45 locations incl. Mobile

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT06561386·Phase 3·Recruiting

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A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer

for Metastatic Non-small Cell Lung Cancer

Drug: Osimertinib

34 locations incl. Fayetteville

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06417814·Phase 3·Recruiting

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CD5-deleted Chimeric Antigen Receptor Cells (Senza5 CART5) for T Cell Non-Hodgkin Lymphoma (NHL)

for T Cell Non-Hodgkin Lymphoma

2 locations incl. New York

Sponsor: Vittoria Biotherapeutics

Sex: All·Age: 18+

Code: NCT06420089·Phase 1·Recruiting

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Imaging Retinal Vasculature in Infant Eyes

for Retinopathy of Prematurity

2 locations incl. Durham

Sponsor: Duke University

Sex: All·Age: Up to 2 Months

Code: NCT05558059·Recruiting

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Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS)

for Acute Respiratory Distress Syndrome

15 locations incl. Irvine

Sponsor: BioAegis Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT05947955·Phase 2·Recruiting

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THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension

for Hypertension

33 locations incl. Birmingham

Sponsor: SoniVie Inc.

Sex: All·Age: 22 - 75

Code: NCT06559891·Recruiting

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Dead Space and Inhaled Nitric Oxide in Pediatric Acute Respiratory Distress Syndrome

for Acute Respiratory Distress Syndrome

10 locations incl. Los Angeles

Sponsor: Children's Hospital Los Angeles

Sex: All·Age: 0 - 21

Code: NCT06690801·Recruiting

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Noncombustible Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers

for E-cigarette Use

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT06372899·Recruiting

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A Trial to Test if TEV-56286 is Effective for Treatment of Participants With Multiple System Atrophy

for Multiple System Atrophy

18 locations incl. La Jolla

Sponsor: Teva Branded Pharmaceutical Products R&D LLC

Sex: All·Age: 30 - 75

Code: NCT06568237·Phase 2·Recruiting

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Strategy Training and Pets to Promote Stroke Survivor's Cognitive Performance and Community Participation

for Stroke

1 location in Pittsburgh

Sponsor: University of Haifa

Sex: All·Age: 18+

Code: NCT05098730·Not Yet Recruiting

Interstitial Photodynamic Therapy Following Palliative Radiotherapy in Treating Patients With Inoperable Malignant Central Airway Obstruction

for Malignant Solid Neoplasm

2 locations incl. Buffalo

Sponsor: Roswell Park Cancer Institute

Sex: All·Age: 18+

Code: NCT06306638·Phase 1, Phase 2·Recruiting

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mindBEAGLE: Unlocking Functional Communication for Patients With Disorders of Consciousness

for Disorders of Consciousness

2 locations incl. Pittsburgh

Sponsor: Amy Wagner

Sex: All·Age: 16 - 65

Code: NCT06426602·Enrolling By Invitation

Trial of Nadofaragene Firadenovec vs. Observation in Participants With Intermediate Risk Non-Muscle Invasive Bladder Cancer

for Intermediate Risk Non-Muscle Invasive Bladder Cancer

Drug: Nadofaragene Firadenovec

49 locations incl. Mobile

Sponsor: Ferring Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06510374·Phase 3·Recruiting

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DISCOVERY of Risk Factors for Type 2 Diabetes in Youth

for Diabetes Mellitus Type 2, Childhood-Onset

20 locations incl. Birmingham

Sponsor: George Washington University

Sex: All·Age: 8 - 15

Code: NCT06525259·Recruiting

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A Trial to Evaluate Intravesical Nadofaragene Firadenovec Alone or in Combination With Chemotherapy or Immunotherapy in Participants With High-grade BCG Unresponsive Non-muscle Invasive Bladder Cancer

for Non-muscle Invasive Bladder Cancer With Carcinoma in Situ

Drug: Nadofaragene Firadenovec

38 locations incl. Tucson

Sponsor: Ferring Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06545955·Phase 3·Recruiting

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Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy

for Diabetic Peripheral Neuropathic Pain

76 locations incl. Anniston

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 80

Code: NCT06628908·Phase 3·Recruiting

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A Dose Response Study to Evaluate the Efficacy and Safety of Oral AP1189 Administered in Disease-Modifying Anti-Rheumatic Drug (DMARD) naïve Participants Participants With Early Rheumatoid Arthritis

for Rheumatoid Arthritis (RA)

3 locations incl. Cutler Bay

Sponsor: SynAct Pharma Aps

Sex: All·Age: 18+

Code: NCT06671054·Phase 2·Recruiting

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Calculating Wall Shear Stress in Infant Pulmonary Veins

for Pulmonary Vein Stenosis

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: Up to 18

Code: NCT06440408·Phase 1·Recruiting

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Supporting Evidence-based Responses to Emotional Needs in Emphysema

for COPD

2 locations incl. Detroit

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06600126·Recruiting

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Long-term Safety and Efficacy Evaluation of Lunsekimig (SAR443765) in Adult Participants With Asthma

for Asthma

Drug: Lunsekimig

27 locations incl. Chandler

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06609239·Phase 2·Enrolling By Invitation

A Multi-Site Clinical Evaluation of the LIAISON NES FLU A/B, RSV & COVID-19 Assay in Symptomatic Patients

for Influenza a

3 locations incl. Henderson

Sponsor: DiaSorin Molecular LLC

Sex: All·Age: All ages

Code: NCT06672692·Recruiting

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Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

for Acute Myeloid Leukemia

Drug: Venetoclax

220 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06317649·Phase 2·Recruiting

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Registry for Stage 2 Type 1 Diabetes

for Type 1 Diabetes

37 locations incl. Los Angeles

Sponsor: Sanofi

Sex: All·Age: All ages

Code: NCT06481904·Recruiting

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A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

for Breast Cancer

165 locations incl. Daphne

Sponsor: Stemline Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06492616·Phase 3·Recruiting

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A Study to Investigate the Safety and Efficacy of GSK4532990 Compared With Placebo in Adult Participants Aged 18 to 70 Years With Alcohol-related Liver Disease

for Liver Diseases, Alcoholic

27 locations incl. Chandler

Sponsor: GlaxoSmithKline

Sex: All·Age: 18 - 70

Code: NCT06613698·Phase 2·Recruiting

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High vs.Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant (SOT) Recipients

for Immunization

8 locations incl. Stanford

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 3 - 17

Code: NCT05947071·Phase 2·Recruiting

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Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia

for Mild Cognitive Impairment

22 locations incl. Atlantis

Sponsor: GAP Innovations, PBC

Sex: All·Age: 60 - 90·Accepts healthy volunteers

Code: NCT06584357·Recruiting

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