Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,479 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 4, 2026.

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3,012 clinical trials

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The Power Down Pilot Study: A Novel Bedtime Manipulation Protocol

for Autism

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 6 - 10

Code: NCT06386029·Recruiting·Listed Apr 2024

Apply to this trial

Clarifying the Optimal Application of SLT Therapy Trial

for Glaucoma and Ocular Hypertension

Sites in Philadelphia, Kingston +25 more locations

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT04967989·Phase 3·Recruiting·Listed Jul 2021

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Study of the ITK Inhibitor Soquelitinib to Reduce Lymphoproliferation and Improve Cytopenias in Autoimmune Lymphoproliferative Syndrome (ALPS)-FAS Patients

for Autoimmune Lymphoproliferative Syndrome

Drug: Soquelitinib

Sites in Philadelphia +2 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 16 - 120

Code: NCT06730126·Phase 2·Recruiting·Listed Dec 2024

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Cardiac Sarcoidosis Randomized Trial

for Cardiac Sarcoidosis

Sites in Pittsburgh +8 more locations

Sponsor: Ottawa Heart Institute Research Corporation

Sex: All·Age: 18+

Code: NCT03593759·Phase 3·Recruiting·Listed Jul 2018

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T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias

for Sickle Cell Anemia

1 location in Pittsburgh

Sponsor: Paul Szabolcs

Sex: All·Age: 5 - 40

Code: NCT03653338·Phase 1, Phase 2·Recruiting·Listed Aug 2018

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Evaluation of Structural and Functional Integrity of the Rotator Cuff After Total Shoulder Arthroplasty

for Osteoarthritis of Shoulder

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 45+

Code: NCT03921944·Recruiting·Listed Apr 2019

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Stress Management and Mindfulness Intervention for Patients With Sickle Cell Disease

for Sickle Cell Disease

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07316478·Recruiting·Listed Jan 2026

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Remimazolam NeuroImaging

for Anesthesia

1 location in Pittsburgh

Sponsor: Keith M Vogt

Sex: All·Age: 18 - 59·Accepts healthy volunteers

Code: NCT07290205·EARLY_Phase 1·Recruiting·Listed Dec 2025

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Frailty Phenotype Assessments to Optimize Treatment Strategies for Older Patients With Hematologic Malignancies

for Leukemia, Acute

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 60+

Code: NCT03680677·Recruiting·Listed Sep 2018

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Improving Care Transitions for Medicaid Insured Individuals With Co-occurring Serious Mental Illness

for Care Transitions

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06203509·Recruiting·Listed Jan 2024

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Systemic Oral Glucocorticoids for the Treatment of Acute Osteoarthritis Pain in the Emergency Department

for Osteoarthritis

1 location in York

Sponsor: WellSpan Health

Sex: All·Age: 18+

Code: NCT06603662·Phase 4·Recruiting·Listed Sep 2024

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How OMT Benefits Newly Diagnosed Patients With Respiratory Illness When Given Alongside Other Standard Care.

for Pneumonia

1 location in Bloomsburg

Sponsor: Geisinger Clinic

Sex: All·Age: 65 - 100

Code: NCT06495021·Recruiting·Listed Jul 2024

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Enhancing Prefrontal Oscillations and Working Memory in Early-course Schizophrenia

for Schizophrenia

1 location in Pittsburgh

Sponsor: Fabio Ferrarelli

Sex: All·Age: 18 - 40

Code: NCT05102929·Recruiting·Listed Nov 2021

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Trauma Resuscitation With Low-Titer Group O Whole Blood or Products

for Wounds and Injuries

Sites in Philadelphia +12 more locations

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 15+

Code: NCT05638581·Phase 3·Recruiting·Listed Dec 2022

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Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney)

for Hiv

Sites in Philadelphia, Pittsburgh +16 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06263426·Recruiting·Listed Feb 2024

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Effects of Operational Naps on Blood Pressure and Performance Among Night Shift Workers

for Shift Work

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07217769·Recruiting·Listed Oct 2025

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Loncastuximab Tesirine and Rituximab Following Stereotactic Radiosurgery in Patients With Central Nervous System Lymphomas (SOLAR)

for Central Nervous System Lymphoma

Drug: Rituximab

Sites in Philadelphia +2 more locations

Sponsor: University of Utah

Sex: All·Age: 18+

Code: NCT06607549·Phase 1·Recruiting·Listed Sep 2024

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Apimostinel + Automated Neurocognitive Training for Depression

for Depression

1 location in Pittsburgh

Sponsor: Rebecca Price

Sex: All·Age: 18 - 60

Code: NCT06400121·Phase 2·Recruiting·Listed May 2024

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Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma

for Barrett's Esophagus

Sites in Philadelphia +9 more locations

Sponsor: Case Western Reserve University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT00288119·Recruiting·Listed Feb 2006

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Biomarkers in Transplant Recipients to Improve Outcomes

for Solid Organ Transplantation

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: All ages

Code: NCT01163578·Recruiting·Listed Jul 2010

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Mapping Disease Pathways for Biliary Atresia

for Biliary Atresia

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: All ages

Code: NCT03273049·Recruiting·Listed Sep 2017

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Molecular Basis of Pediatric Liver Cancer

for Childhood Liver Cancer

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 0 - 99

Code: NCT03959800·Recruiting·Listed May 2019

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Tocilizumab in Lung Transplantation

for Lung Transplant

Drug: Tocilizumab

Sites in Philadelphia +16 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 12 - 75

Code: NCT06033196·Phase 2·Recruiting·Listed Sep 2023

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Practical Geriatric Assessment (PGA) Implementation Strategies and Correlative Evaluations (PACE-70)

for Geriatric Assessment

Sites in Philadelphia, Lancaster +1 more location

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 70+

Code: NCT06870617·Recruiting·Listed Mar 2025

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Optimizing Pain Treatment in Children On Mechanical Ventilation

for Mechanical Ventilation

Sites in Philadelphia, Pittsburgh +14 more locations

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 2 Months - 17

Code: NCT06994442·Phase 3·Recruiting·Listed May 2025

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ASSESS ALL ALS Study

for Amyotrophic Lateral Sclerosis

Sites in Philadelphia, Hershey +34 more locations

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06578195·Recruiting·Listed Aug 2024

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Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma

for AIDS-Related Diffuse Large B-cell Lymphoma

Sites in Philadelphia +6 more locations

Sponsor: AIDS Malignancy Consortium

Sex: All·Age: 18+

Code: NCT05077527·Phase 1·Recruiting·Listed Oct 2021

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Prospective Research Rare Kidney Stones (ProRKS)

for Hyperoxaluria

Sites in Philadelphia +7 more locations

Sponsor: Mayo Clinic

Sex: All·Age: All ages

Code: NCT02780297·Recruiting·Listed May 2016

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Refer2Quit: Evaluating a Proactive, Tailored, Population Health Approach for Tobacco Treatment for Household Smokers Through a Pediatric Care Network

for Smoking

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 18+

Code: NCT06582693·Recruiting·Listed Sep 2024

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Measuring the Effect of Dupilumab Treatment on Mucociliary Clearance (MCC) in Subjects With Moderate to Severe Asthma

for Asthma

Drug: Dupilumab

1 location in Pittsburgh

Sponsor: Sally E. Wenzel MD

Sex: All·Age: 18+

Code: NCT04743791·Phase 4·Recruiting·Listed Feb 2021

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WBSI Guided Personalized Delivery of TTFields

for GBM

2 locations in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 22+

Code: NCT05086497·Recruiting·Listed Oct 2021

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Enfortumab Vedotin Plus Pembrolizumab With Selective Bladder Sparing for Treatment of Muscle-invasive Bladder Cancer

for Muscle Invasive Bladder Urothelial Carcinoma

Sites in Philadelphia +4 more locations

Sponsor: Matthew Galsky

Sex: All·Age: 18+

Code: NCT06809140·Phase 2·Recruiting·Listed Feb 2025

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Genomic Profiling in Cancer Patients

for Solid Tumors

Sites in Allentown +17 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: All ages

Code: NCT01775072·Recruiting·Listed Jan 2013

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Testing the Combination of Anti-cancer Drugs, Tovorafenib Plus Rituximab, in Patients With Hairy Cell Leukemia

for Hairy Cell Leukemia

Drug: Rituximab

Sites in Pittsburgh +3 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06965114·Phase 1, Phase 2·Recruiting·Listed May 2025

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Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathy

for Radiation Retinopathy

Sites in Philadelphia, Monroeville +25 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 18+

Code: NCT05844982·Phase 3·Recruiting·Listed May 2023

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Calculating Wall Shear Stress in Infant Pulmonary Veins

for Pulmonary Vein Stenosis

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: Up to 18

Code: NCT06440408·Phase 1·Recruiting·Listed Jun 2024

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Platform Clinical Study for Conquering Scleroderma

for Interstitial Lung Disease Due to Systemic Disease

Sites in Philadelphia +23 more locations

Sponsor: Scleroderma Research Foundation, Inc.

Sex: All·Age: 18+

Code: NCT06195072·Phase 2·Recruiting·Listed Jan 2024

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A Prospective Natural History Study of Lymphatic Anomalies

for Lymphatic Diseases

Sites in Philadelphia +1 more location

Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Sex: All·Age: 1 Day - 100·Accepts healthy volunteers

Code: NCT05731141·Recruiting·Listed Feb 2023

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Pilot Study: Establishing Glutamatergic Changes in Rapid Antidepressant Effects of Ketamine

for Major Depressive Disorder (MDD)

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 25 - 65

Code: NCT06788249·EARLY_Phase 1·Recruiting·Listed Jan 2025

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Predicting and Preventing Adverse Maternal and Child Outcomes of Opioid Use Disorder in Pregnancy

for Opioid Use Disorder

1 location in Pittsburgh

Sponsor: Ilana Hull

Sex: Female·Age: 18+

Code: NCT05942313·Recruiting·Listed Jul 2023

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