Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,654 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 9, 2026.

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3,654 clinical trials

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The Effects of Healthy Diets With Plant Oils on Heart and Metabolic Health

for Cardiovascular Diseases

1 location in University Park

Sponsor: Penn State University

Sex: All·Age: 25 - 60·Accepts healthy volunteers

Code: NCT06216678·Recruiting

Apply to this trial

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

for Melanoma

104 locations incl. Chandler

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06246916·Phase 3·Recruiting

Apply to this trial

Safety and Effectiveness of Mechanical Thrombectomy Using the Anaconda ANA Funnel Catheter

for Acute Ischemic Stroke From Large Vessel Occlusion

11 locations incl. Jacksonville

Sponsor: Anaconda Biomed S.L.

Sex: All·Age: 22 - 85

Code: NCT06370182·Recruiting

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RevCore for In Stent Thrombosis

for In-stent Thrombosis

16 locations incl. New Haven

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT06394739·Recruiting

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Refer2Quit: Evaluating a Proactive, Tailored, Population Health Approach for Tobacco Treatment for Household Smokers Through a Pediatric Care Network

for Smoking

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 18+

Code: NCT06582693·Recruiting

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A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

for NASH - Nonalcoholic Steatohepatitis

Drug: Efruxifermin

168 locations incl. Birmingham

Sponsor: Akero Therapeutics, Inc

Sex: All·Age: 18 - 80

Code: NCT06528314·Phase 3·Recruiting

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Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease

for Crohn's Disease

64 locations incl. Dothan

Sponsor: AbbVie

Sex: All·Age: 18 - 75

Code: NCT06548542·Phase 2·Recruiting

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A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (the APEX Study)

for Pulmonary Hypertension

31 locations incl. Phoenix

Sponsor: Tectonic Therapeutic

Sex: All·Age: 18 - 83

Code: NCT06616974·Phase 2·Recruiting

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Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes

for Lung Transplant

18 locations incl. Los Angeles

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06399302·Recruiting

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PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm

for Coronary Artery Disease

18 locations incl. Chandler

Sponsor: Kardion Inc

Sex: All·Age: 18 - 90

Code: NCT06445608·Recruiting

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First-in-human Study of DB-1419 for Advanced/Metastatic Solid Tumors

for Solid Tumor, Adult

9 locations incl. Los Angeles

Sponsor: DualityBio Inc.

Sex: All·Age: 18+

Code: NCT06554795·Phase 1, Phase 2·Recruiting

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Frequency of Selected Single Nucleotide Polymorphisms in Huntington Disease Gene Expansion Carriers

for Huntington Disease

13 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 25 - 60

Code: NCT06667414·Recruiting

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Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes

for Gestational Diabetes

2 locations incl. Rochester

Sponsor: Thomas Jefferson University

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06419777·Recruiting

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Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes (START 2)

for Gestational Diabetes

2 locations incl. Rochester

Sponsor: Thomas Jefferson University

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06419803·Recruiting

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Pilot Trial of the RUBI Program for Autistic Adults

for Autism Spectrum Disorder

3 locations incl. Jupiter

Sponsor: Seattle Children's Hospital

Sex: All·Age: 18+

Code: NCT06593613·Recruiting

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Timing Impact of Early vs. Late Cranioplasty on Hemicraniectomy Outcomes

for Craniocerebral Trauma

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06632587·Recruiting

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Taking Action for College Students

for Major Depressive Disorder

1 location in Philadelphia

Sponsor: Temple University

Sex: All·Age: 18+

Code: NCT06700902·Recruiting

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CRS Questionnaire Validation Project

for Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps

5 locations incl. Santa Monica

Sponsor: The European Forum for Research and Education in Allergy and Airway Diseases

Sex: All·Age: 18+

Code: NCT06970977·Recruiting

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MILC: A Comprehensive Mobile Application That Addresses the Breastfeeding Challenges of Low-income Hispanic Mothers

for Breastfeeding, Exclusive

3 locations incl. Farmington

Sponsor: Benten Technologies, Inc.

Sex: Female·Age: 18 - 44·Accepts healthy volunteers

Code: NCT06520696·Not Yet Recruiting

EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)

for Kidney Disease, Chronic

Drug: Empagliflozin

39 locations incl. Huntsville

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06531824·Phase 3·Recruiting

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A Study of Bleeding and Treatment in Participants With Von Willebrand Disease

for Von Willebrand Disease (VWD)

13 locations incl. Phoenix

Sponsor: Hemab ApS

Sex: All·Age: 16+

Code: NCT06610201·Recruiting

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KYSA-6: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, in Patients With Generalized Myasthenia Gravis

for Myasthenia Gravis

8 locations incl. Orange

Sponsor: Kyverna Therapeutics

Sex: All·Age: 18 - 75

Code: NCT06193889·Phase 2, Phase 3·Recruiting

Apply to this trial

Reducing Urban Cervical Cancer Disparities

for Cervical Cancer

3 locations incl. New Brunswick

Sponsor: Fox Chase Cancer Center

Sex: Female·Age: 18 - 90·Accepts healthy volunteers

Code: NCT06416150·Recruiting

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A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

for Advanced Non-small Cell Lung Cancer

27 locations incl. Newport Beach

Sponsor: Bayer

Sex: All·Age: 18+

Code: NCT06452277·Phase 3·Recruiting

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First In Human Study of CX-801 in Advanced Solid Tumors

for Solid Tumor, Adult

3 locations incl. Englewood

Sponsor: CytomX Therapeutics

Sex: All·Age: 18+

Code: NCT06462794·Phase 1·Recruiting

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Trial of Transurethral Bulking Agent Injection Versus Single-Incision Sling for Stress Urinary Incontinence

for Stress Urinary Incontinence

7 locations incl. La Jolla

Sponsor: NICHD Pelvic Floor Disorders Network

Sex: Female·Age: 21+

Code: NCT06480227·Recruiting

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Iberdomide Versus Observation Off Therapy After Idecabtagene Vicleucel CAR-T for Multiple Myeloma

for Multiple Myeloma

Drug: Iberdomide

74 locations incl. Irvine

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06179888·Phase 2·Recruiting

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Modified Platform Trial Evaluating PpLHACM and SOC Versus SOC Alone in the Treatment of Nonhealing DFUs

for Diabetic Foot Ulcer

1 location in Monroeville

Sponsor: MiMedx Group, Inc.

Sex: All·Age: 18+

Code: NCT06600724·Recruiting

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The Role of Flavor in the Substitutability of E-cigarettes for Combustible Cigarettes Among Persistent Smokers

for Smoking

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT06264154·Recruiting

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Exparel v Dexamethasone in RCR

for Rotator Cuff Tears

1 location in Philadelphia

Sponsor: Rothman Institute Orthopaedics

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06575010·Phase 4·Enrolling By Invitation

Safety, Pharmacokinetics (PK), and Efficacy of ONC 841 in Advanced Solid Tumors

for Advanced Solid Tumor

8 locations incl. Sacramento

Sponsor: OncoC4, Inc.

Sex: All·Age: 18+

Code: NCT06352359·Phase 1·Recruiting

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Effects of Mindfulness and Yoga on Preschool Students' Emotional Regulation, Behavior, and Social Participation

for Prosocial Behavior

1 location in Elizabethtown

Sponsor: Elizabethtown College

Sex: All·Age: 4 - 6·Accepts healthy volunteers

Code: NCT06561373·Not Yet Recruiting

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

for High Grade Glioma

Drug: Ribociclib

11 locations incl. Aurora

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 12 Months - 39

Code: NCT05843253·Phase 2·Recruiting

Apply to this trial

Letrozole and Misoprostol for Early Pregnancy Loss Management

for Early Pregnancy Loss

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: Female·Age: 18+

Code: NCT06452719·Phase 2·Recruiting

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Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer

for Refractory Differentiated Thyroid Gland Carcinoma

301 locations incl. Anchorage

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT06475989·Phase 3·Recruiting

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Study of Volrustomig as Monotherapy or in Combination With Anti- Cancer Agents in Participants With Advanced/Metastatic Solid Tumors

for Sub-study 1 Cervical Cancer (Volrustomig Monotherapy)

6 locations incl. Los Angeles

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06535607·Phase 2·Recruiting

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A Study to Test the Efficacy and Safety of Riliprubart Against the Usual Treatment of Intravenous Immunoglobulin (IVIg) in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

for Chronic Inflammatory Demyelinating Polyneuropathy

Drug: riliprubart

29 locations incl. Homewood

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06290141·Phase 3·Recruiting

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School Partnered Collaborative Care (SPACE) Intervention for Children With Type 1 Diabetes

for Type 1 Diabetes

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 5 - 12

Code: NCT06420661·Enrolling By Invitation

Abbott Structural Heart Device Registry

for Heart Diseases

5 locations incl. New Brunswick

Sponsor: Abbott Medical Devices

Sex: All·Age: All ages

Code: NCT06590467·Recruiting

Apply to this trial

EMAGINE 2.0 - Electromagnetic Field Ischemic Stroke - Novel Subacute Treatment

for Ischemic Stroke

14 locations incl. Downey

Sponsor: BrainQ Technologies Ltd.

Sex: All·Age: 22 - 80

Code: NCT06386874·Recruiting

Apply to this trial