Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,479 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 4, 2026.

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3,012 clinical trials

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Ruxolitinib vs Prednisone as First-line Therapy for cGVHD Needing Systemic Therapy

for Chronic Graft-versus-host Disease (cGVHD)

Drug: Ruxolitinib

Sites in Philadelphia +5 more locations

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06660355·Phase 2·Recruiting·Listed Oct 2024

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Virtual Mindful After Cancer (MAC) Intervention to Promote Sexual Health for Breast and Gynecologic Cancer Survivors

for Gynecologic Cancers

Sites in Philadelphia +2 more locations

Sponsor: Oregon State University

Sex: Female·Age: 18+

Code: NCT07055854·Phase 1·Recruiting·Listed Jul 2025

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Catalyzing Cigarette Smoking Cessation Through Harm Reduction Sampling Among People Unmotivated to Quit

for Cigarette Smoking

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT07199517·Recruiting·Listed Sep 2025

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Adapting the Penny Chatbot for Perinatal OUD Patients: COPILOT

for Perinatal Opioid Use Disorder

2 locations in Philadelphia

Sponsor: University of Pennsylvania

Sex: Female·Age: All ages

Code: NCT06969261·Recruiting·Listed May 2025

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PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation

for Infections

Sites in Hershey +12 more locations

Sponsor: Major Extremity Trauma Research Consortium

Sex: All·Age: 18+

Code: NCT05699174·Phase 3·Recruiting·Listed Jan 2023

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MicroRNAs as Biomarkers for Obstructive Sleep Apnea

for Obstructive Sleep Apnea

Sites in Philadelphia +1 more location

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 75

Code: NCT06189755·Recruiting·Listed Jan 2024

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Childhood Cancer Survivor Study

for Cancer

Sites in Philadelphia, Pittsburgh +25 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01120353·Recruiting·Listed May 2010

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Maintenance Combinatorial Myeloid Immunotherapy for Unresectable Pancreatic Cancer

for Pancreatic Ductal Adenocarcinoma

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07199764·Phase 2·Recruiting·Listed Sep 2025

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Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

for Lung Non-Small Cell Carcinoma

Sites in Danville, York +241 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06116682·Phase 2·Recruiting·Listed Nov 2023

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Effect of Music Therapy on Infants With Neonatal Abstinence Syndrome

for NAS

Sites in Philadelphia +5 more locations

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 28 Weeks+

Code: NCT03533985·Recruiting·Listed May 2018

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Testing the Safety and Efficacy of the Addition of a New Anti-cancer Drug, ZEN003694, to Chemotherapy Treatment (Cisplatin and Etoposide or Carboplatin and Paclitaxel) for Adult and Pediatric Patients (12-17 Years) With NUT Carcinoma

for Advanced NUT Carcinoma

Sites in Pittsburgh +4 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12+

Code: NCT05019716·Phase 1, Phase 2·Recruiting·Listed Aug 2021

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Enhancing Memory in Cognitive Processing Therapy for PTSD

for Stress Disorders, Post-Traumatic

1 location in Philadelphia

Sponsor: VA Office of Research and Development

Sex: All·Age: 60+

Code: NCT06000475·Recruiting·Listed Aug 2023

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BLOCK-SAH - PPF-Block for Post-SAH Headache

for Subarachnoid Hemorrhage, Aneurysmal

Sites in Philadelphia +12 more locations

Sponsor: University of Florida

Sex: All·Age: 18 - 85

Code: NCT06008795·Phase 2·Recruiting·Listed Aug 2023

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Multidimensional Phenotype Classification in Grade 3 Bronchopulmonary Dysplasia

for Bronchopulmonary Dysplasia

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 1 Month - 1

Code: NCT06475976·Recruiting·Listed Jun 2024

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Trial of an Alternative Cabozantinib Dosing Schedule in Metastatic Renal Cell Carcinoma and Neuroendocrine Tumors

for Metastatic Renal Cell Carcinoma

Drug: Cabozantinib

1 location in Philadelphia

Sponsor: Fox Chase Cancer Center

Sex: All·Age: 18+

Code: NCT05263050·Phase 2·Recruiting·Listed Mar 2022

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Advanced SPinal Innovations With Robotics and Enabling Technology Registry

for Spine Deformity

Sites in Bethlehem +9 more locations

Sponsor: Boston Children's Hospital

Sex: All·Age: 0 - 21·Accepts healthy volunteers

Code: NCT05071144·Recruiting·Listed Oct 2021

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Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors

for Anatomic Stage III Breast Cancer AJCC v8

Sites in Pittsburgh +6 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12+

Code: NCT05372640·Phase 1·Recruiting·Listed May 2022

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Pharmacogenetics of Response to GLP1R Agonists

for Obesity

1 location in Lancaster

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 89·Accepts healthy volunteers

Code: NCT05071898·Phase 1·Recruiting·Listed Oct 2021

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Offset Mechanisms in Evaluation of Lumbar Medial Branch Blocks

for Pain, Chronic

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT05961800·Recruiting·Listed Jul 2023

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CEUS Evaluation of Hydrocephalus in Neonates and Infants

for Hydrocephalus in Infants

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 1 Minute - 18 Months

Code: NCT06693752·Phase 2·Recruiting·Listed Nov 2024

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Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE)

for Differentiated Thyroid Cancer

Sites in Philadelphia +3 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 2 - 25

Code: NCT06458036·Phase 2·Recruiting·Listed Jun 2024

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Improving Prosthetic Arms for Amputee: A Better Fit and More Functionality

for Amputation, Surgical

1 location in Pittsburgh

Sponsor: VA Office of Research and Development

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT05990062·Recruiting·Listed Aug 2023

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Chronic Subdural Hematoma Treatment With Embolization Versus Surgery Study

for Chronic Subdural Hematoma

Sites in Philadelphia, Upland +27 more locations

Sponsor: The University of Texas Medical Branch, Galveston

Sex: All·Age: 40 - 90

Code: NCT06347796·Recruiting·Listed Apr 2024

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CTSN Embolic Protection Trial

for Delirium

Sites in Philadelphia +18 more locations

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 60+

Code: NCT06027788·Recruiting·Listed Sep 2023

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Safety and Efficacy of FETO in CDH: A Phase III Trial

for Congenital Diaphragmatic Hernia

1 location in Philadelphia

Sponsor: Holly L Hedrick, MD

Sex: Female·Age: 18+

Code: NCT06884423·Recruiting·Listed Mar 2025

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Evaluation of Analgesia for Cardiac Elective Surgery in Children

for Pediatric Cardiac Surgery

Sites in Pittsburgh +2 more locations

Sponsor: Senthil Sadhasivam

Sex: All·Age: 3 - 18

Code: NCT06626035·Phase 3·Recruiting·Listed Oct 2024

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Evaluating Verbal Communication in Structured Interactions: Theoretical and Clinical Implications

for Amyotrophic Lateral Sclerosis

1 location in University Park

Sponsor: Penn State University

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT06266403·Recruiting·Listed Feb 2024

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PEACH TRIAL- Precision Medicine and Adoptive Cellular Therapy

for Neuroblastoma

Sites in Hershey +1 more location

Sponsor: University of Florida

Sex: All·Age: 1 - 30

Code: NCT04837547·Phase 1·Recruiting·Listed Apr 2021

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Evaluation of Grief Therapy Approaches for Bereaved Parents

for Grief

Sites in Philadelphia +4 more locations

Sponsor: University of Miami

Sex: All·Age: 18+

Code: NCT05142605·Recruiting·Listed Dec 2021

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Biomechanical Validation of the Caregiver Assisted Transfer Technique Instrument

for Informal Caregivers

1 location in Pittsburgh

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT06013878·Recruiting·Listed Aug 2023

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Nephrotic Syndrome Study Network

for Minimal Change Disease (MCD)

Sites in Philadelphia +33 more locations

Sponsor: University of Michigan

Sex: All·Age: Up to 80

Code: NCT01209000·Recruiting·Listed Sep 2010

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Acceptance and Commitment Therapy Integrated Vestibular Rehabilitation (ACTIVE) RCT

for Concussion, Mild

Sites in Pittsburgh +1 more location

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 49

Code: NCT06819904·Recruiting·Listed Feb 2025

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Impact of Brief Daily Functional Resistance Training on Lower Extremity Physical Performance

for Mobility Limitation

Sites in Pittsburgh & Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 65+

Code: NCT06396247·Phase 2, Phase 3·Recruiting·Listed May 2024

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Risk Factors That Increase the Chance of Developing Primary Graft Dysfunction After Lung Transplantation

for Primary Graft Dysfunction

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 13 - 68

Code: NCT00552357·Recruiting·Listed Nov 2007

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How Hormones and Exposure and Response Prevention (EX/RP) Affect the Brain of People With OCD

for OCD

Sites in Philadelphia +1 more location

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 45

Code: NCT05359562·Recruiting·Listed May 2022

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Randomized Trial Comparing Immediate vs. Deferred Surgery for Symptomatic ERM

for Epiretinal Membrane

Sites in Philadelphia, Monroeville +45 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 50+

Code: NCT05145491·Recruiting·Listed Dec 2021

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Tebentafusp-tebn With LDT in Metastatic UM

for Metastatic Uveal Melanoma

Drug: Tebentafusp

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT06626516·Phase 1, Phase 2·Recruiting·Listed Oct 2024

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Belimumab With Rituximab for Primary Membranous Nephropathy

for Membranous Nephropathy

Drug: Rituximab

Sites in Philadelphia +19 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 75

Code: NCT03949855·Phase 2·Recruiting·Listed May 2019

Apply to this trial

Community Resiliency Collective Efficacy Intervention

for Violence, Physical

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 13+·Accepts healthy volunteers

Code: NCT05768217·Recruiting·Listed Mar 2023

Apply to this trial

CGM for Management of Type 2 Diabetes in Pregnancy

for Type 2 Diabetes Mellitus (T2DM)

Sites in Philadelphia +6 more locations

Sponsor: University of Alabama at Birmingham

Sex: Female·Age: 18 - 50

Code: NCT06628453·Recruiting·Listed Oct 2024

Apply to this trial