Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,479 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 4, 2026.

Filter results

Filter results

State

City

Recruitment status

Phase

Study type

Intervention

Condition

Sex

Age

Healthy volunteers only

3,012 clinical trials

Get a weekly email when new trials open in Philadelphia, PA.

Combined Oral Contraceptive Pill and Resistance Starch

for Metabolic Syndrome

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: Female·Age: 18 - 40

Code: NCT06852365·Phase 2·Recruiting·Listed Feb 2025

Apply to this trial

Lanreotide Versus Placebo Before Surgery to Prevent a Surgical Complication Called a Pancreatic Fistula

for Pancreatic Carcinoma

Sites in Allentown, Bethlehem +16 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06807437·Phase 3·Recruiting·Listed Feb 2025

Apply to this trial

Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

for AL Amyloidosis

Sites in Philadelphia, Danville +114 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06022939·Phase 3·Recruiting·Listed Sep 2023

Apply to this trial

Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Philadelphia, Pittsburgh +913 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05929768·Phase 3·Recruiting·Listed Jul 2023

Apply to this trial

Intralesional 5-Fluorouracil (5FU), Topical Calcipotriene Treatment for SCC

for Carcinoma, Squamous Cell

1 location in Pittsburgh

Sponsor: Melissa Pugliano-Mauro

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT03370406·Phase 1·Recruiting·Listed Dec 2017

Apply to this trial

A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma

for Plasmablastic Lymphoma

Drug: Daratumumab

Sites in Philadelphia +7 more locations

Sponsor: AIDS Malignancy Consortium

Sex: All·Age: 18+

Code: NCT04139304·EARLY_Phase 1·Recruiting·Listed Oct 2019

Apply to this trial

Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL

for Hypertensive Disorders of Pregnancy

Sites in Pittsburgh +15 more locations

Sponsor: Ohio State University

Sex: Female·Age: 14 - 35

Code: NCT06468202·Phase 4·Recruiting·Listed Jun 2024

Apply to this trial

Ketamine add-on Therapy for Established Status Epilepticus Treatment Trial (KESETT)

for Status Epilepticus

Sites in Philadelphia, Pittsburgh +50 more locations

Sponsor: University of Virginia

Sex: All·Age: 1+

Code: NCT06907173·Phase 3·Recruiting·Listed Apr 2025

Apply to this trial

Determining the Effects of Non-invasive Brain Stimulation to Improve Quadriceps Muscle Function After ACL Reconstruction

for Anterior Cruciate Ligament Reconstruction Rehabilitation

1 location in Glenside

Sponsor: Arcadia University

Sex: Female·Age: 18 - 35

Code: NCT07128602·Recruiting·Listed Aug 2025

Apply to this trial

Communication About Sexual Health in Gynecologic Cancer

for Gynecologic Cancers

1 location in Philadelphia

Sponsor: Fox Chase Cancer Center

Sex: Female·Age: 18+

Code: NCT06904339·Recruiting·Listed Apr 2025

Apply to this trial

A Socio-ecological Approach for Improving Self-management in Adolescents With SCD

for Anemia, Sickle Cell

Sites in Philadelphia +3 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 13 - 21

Code: NCT06290401·Recruiting·Listed Mar 2024

Apply to this trial

Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors

for Metastatic Malignant Neoplasm in the Liver

Sites in Philadelphia +379 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05040360·Phase 2·Recruiting·Listed Sep 2021

Apply to this trial

Tovorafenib for Treatment of Craniopharyngioma in Children and Young Adults

for Craniopharyngioma, Child

Sites in Philadelphia +14 more locations

Sponsor: Sabine Mueller, MD, PhD

Sex: All·Age: 1 - 39

Code: NCT05465174·Phase 2·Recruiting·Listed Jul 2022

Apply to this trial

Short Course Radiotherapy

for Central Nervous System Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: Up to 21

Code: NCT07147179·Recruiting·Listed Aug 2025

Apply to this trial

Integrating Telehealth to Advance Lung Cancer Screening

for Early Detection of Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 50 - 80

Code: NCT06638554·Recruiting·Listed Oct 2024

Apply to this trial

Assessment of Multi-Level Interventions to Improve Adherence to Oral Medications in Cancer Patients

for Cancer

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT03245411·Recruiting·Listed Aug 2017

Apply to this trial

Support and Outreach to Increase Screening for Lung Cancer in Patients With a History of Smoking

for Lung Carcinoma

1 location in Philadelphia

Sponsor: Ronald Myers

Sex: All·Age: 50 - 77·Accepts healthy volunteers

Code: NCT05679349·Recruiting·Listed Jan 2023

Apply to this trial

LATe Cerclage in High-risk Pregnancies (LATCH)

for Premature Birth

Sites in Philadelphia +1 more location

Sponsor: Thomas Jefferson University

Sex: Female·Age: 18 - 50·Accepts healthy volunteers

Code: NCT06036446·Recruiting·Listed Sep 2023

Apply to this trial

Validation of Clinical Outcome Measures Specific to mTBI-Related Oculomotor Disorders

for MTBI - Mild Traumatic Brain Injury

1 location in Philadelphia

Sponsor: Salus University

Sex: All·Age: 18 - 35·Accepts healthy volunteers

Code: NCT07282691·Recruiting·Listed Dec 2025

Apply to this trial

Diet and Motility in IBS

for Irritable Bowel Syndrome (IBS)

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 8 - 18·Accepts healthy volunteers

Code: NCT07283341·Recruiting·Listed Dec 2025

Apply to this trial

Parasitic Ulcer Treatment Trial

for Acanthamoeba Keratitis

Sites in Philadelphia, Pittsburgh +11 more locations

Sponsor: Jeremy Keenan, MD, MPH

Sex: All·Age: 8+

Code: NCT06213649·Phase 3·Recruiting·Listed Jan 2024

Apply to this trial

Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone

for Giant Cell Tumor of Bone

Sites in Pittsburgh +10 more locations

Sponsor: St. Louis University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT03295981·Phase 3·Recruiting·Listed Sep 2017

Apply to this trial

Study of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and Efficacy

for Acute Myeloid Leukemia

Sites in Hershey +8 more locations

Sponsor: Norman J. Lacayo

Sex: All·Age: Up to 21

Code: NCT05101551·Phase 1·Recruiting·Listed Nov 2021

Apply to this trial

Clinical and Biomarker Effects of Depot Medroxyprogesterone Acetate in Females With Sickle Cell Disease

for Sickle Cell Disease (SCD)

Sites in Philadelphia +1 more location

Sponsor: University of Pennsylvania

Sex: Female·Age: 18 - 50

Code: NCT06665997·Phase 4·Recruiting·Listed Oct 2024

Apply to this trial

Epcoritamab-CAR T Cells for Large B-cell Lymphomas

for Lymphoma, Non-Hodgkin

Drug: Epcoritamab

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT06458439·Phase 2·Recruiting·Listed Jun 2024

Apply to this trial

Osteochondritis Dissecans of Knee Prospective Cohort

for Osteochondritis Dissecans

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: All ages

Code: NCT02771496·Recruiting·Listed May 2016

Apply to this trial

Optimizing a Mobile Health Platform for Sleep Promotion and Obesity Prevention in Children

for Insufficient Sleep

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 8 - 12·Accepts healthy volunteers

Code: NCT05703347·Recruiting·Listed Jan 2023

Apply to this trial

A Study of Targeted Radiation Therapy in People With Non-Small Cell Lung Cancer (NSCLC)

for Non Small Cell Lung Cancer

Sites in Allentown +8 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT05657873·Phase 2·Recruiting·Listed Dec 2022

Apply to this trial

ABemacicliB or Abemaciclib and HydroxYchloroquine to Target Minimal Residual Disease in Breast Cancer

for Breast Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT04523857·Phase 2·Recruiting·Listed Aug 2020

Apply to this trial

CAR-T Followed by Bispecific Antibodies

for Large B-cell Lymphoma

Sites in Philadelphia +1 more location

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT04889716·Phase 2·Recruiting·Listed May 2021

Apply to this trial

Autologous HuCART19 T Cells Manufactured Using the CliniMACS Prodigy Platform for Pediatric B-ALL (huCART19 Prodigy)

for B Cell Acute Lymphoblastic Leukemia (B-ALL)

1 location in Philadelphia

Sponsor: Stephan Grupp MD PhD

Sex: All·Age: 0 - 29

Code: NCT05480449·Phase 1, Phase 2·Recruiting·Listed Jul 2022

Apply to this trial

The Impact of Botox on Neuroimmune Interactions in Atopic Dermatitis

for Atopic Dermatitis (AD)

2 locations in Pittsburgh

Sponsor: Daniel Kaplan

Sex: All·Age: 18+

Code: NCT06928246·Phase 1·Recruiting·Listed Apr 2025

Apply to this trial

Neuromodulation of Brain and Emotional Responses to Psychological Stress

for Healthy

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 30 - 50·Accepts healthy volunteers

Code: NCT06603064·Recruiting·Listed Sep 2024

Apply to this trial

Clinical Trial to Evaluate Post-Operative Outcomes of Ureteral Stent vs Ureteral Stent Free Radical Cystectomy

for Bladder Cancer

2 locations in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18 - 85

Code: NCT07234968·Recruiting·Listed Nov 2025

Apply to this trial

CYTALUX for Intraoperative Imaging of Patients With Endometrial Cancer

for Endometrial Cancer

2 locations in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Female·Age: 18+

Code: NCT07278986·EARLY_Phase 1·Recruiting·Listed Dec 2025

Apply to this trial

Active Surveillance in Older Women With ER+ Breast Cancer

for Early Stage Estrogen Receptor (ER) Positive Breast Cancer

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Female·Age: 70+

Code: NCT07262138·Recruiting·Listed Dec 2025

Apply to this trial

Impact of Biophoton Therapy on Chronic Severe Arthritis Pain

for Arthritis

1 location in Butler

Sponsor: First Institute of All Medicines

Sex: All·Age: 18 - 80

Code: NCT06915012·Recruiting·Listed Apr 2025

Apply to this trial

DISCOVERY of Risk Factors for Type 2 Diabetes in Youth

for Diabetes Mellitus Type 2, Childhood-Onset

Sites in Philadelphia +19 more locations

Sponsor: George Washington University

Sex: All·Age: 8 - 15

Code: NCT06525259·Recruiting·Listed Jul 2024

Apply to this trial

Menopausal HT for Women Living With HIV (HoT)

for HIV Infection

Sites in Philadelphia, Pittsburgh +21 more locations

Sponsor: Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections

Sex: Female·Age: 40 - 60

Code: NCT06856174·Phase 4·Recruiting·Listed Mar 2025

Apply to this trial

Sense4Safety Intervention

for Mild Cognitive Impairment

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 65+

Code: NCT07220668·Phase 1, Phase 2·Recruiting·Listed Oct 2025

Apply to this trial