Brain disorders Clinical Trials in Philadelphia, PA

As of September 2026, 68 paid clinical trials are recruiting for Brain disorders in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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68 clinical trials for Brain disorders

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Central Vein Sign in Multiple Sclerosis Extension Study

for Multiple Sclerosis

Sites in Philadelphia +2 more locations

Sponsor: The Cleveland Clinic

Sex: All·Age: 18 - 65

Code: NCT07424027·Recruiting·Listed Feb 2026

Apply to this trial

tACS to Enhance Language Abilities

for Stroke

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT06092814·Recruiting·Listed Oct 2023

Apply to this trial

ASSESS ALL ALS Study

for Amyotrophic Lateral Sclerosis

Sites in Philadelphia, Hershey +34 more locations

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06578195·Recruiting·Listed Aug 2024

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Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

Sites in Philadelphia, Hershey +140 more locations

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting·Listed Apr 2019

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CTSN Embolic Protection Trial

for Delirium

Sites in Philadelphia +18 more locations

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 60+

Code: NCT06027788·Recruiting·Listed Sep 2023

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PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

for Parkinson Disease

Sites in Philadelphia, Pittsburgh +28 more locations

Sponsor: Michael J. Fox Foundation for Parkinson's Research

Sex: All·Age: 30+·Accepts healthy volunteers

Code: NCT04477785·Recruiting·Listed Jul 2020

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Electrographic Seizure Management and Neurobehavioral Outcomes in Critically Ill Children

for Seizures

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 1 Month - 18

Code: NCT03419260·Recruiting·Listed Feb 2018

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Transcranial Magnetic Stimulation + Language Therapy to Treat Subacute Aphasia

for Stroke

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 85

Code: NCT06968663·Phase 2·Recruiting·Listed May 2025

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Facilitating Access to Specialty Treatment

for Mild Traumatic Brain Injury

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 13 - 18

Code: NCT05741411·Recruiting·Listed Feb 2023

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Stroke Thrombectomy and Aneurysm Registry

for Stroke

Sites in Philadelphia, York +52 more locations

Sponsor: Medical University of South Carolina

Sex: All·Age: 1 - 120

Code: NCT04994756·Recruiting·Listed Aug 2021

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Sense4Safety Intervention

for Mild Cognitive Impairment

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 65+

Code: NCT07220668·Phase 1, Phase 2·Recruiting·Listed Oct 2025

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Longitudinal Assessment of Traumatic Microvascular Injury-2

for Traumatic Brain Injury

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05725993·Recruiting·Listed Feb 2023

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Promoting Recovery After STroke With Amantadine

for Stroke, Ischemic

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 85

Code: NCT05140148·Phase 2·Recruiting·Listed Dec 2021

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Optimizing the Prehospital Use of Stroke Systems of Care-Reacting to Changing Paradigms-Implementation (OPUS-i)

for Stroke

Sites in Philadelphia +1 more location

Sponsor: Temple University

Sex: All·Age: 18+

Code: NCT06530693·Recruiting·Listed Jul 2024

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StrokeNet Thrombectomy Endovascular Platform

for Ischemic Stroke

Sites in Philadelphia, Pittsburgh +39 more locations

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06289985·Recruiting·Listed Mar 2024

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Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

for Atrial Fibrillation

Sites in Philadelphia +34 more locations

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT04045665·Phase 3·Recruiting·Listed Aug 2019

Apply to this trial

Localizing Epileptic Networks Using MRI and iEEG

for Epilepsy

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04649008·EARLY_Phase 1·Recruiting·Listed Dec 2020

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Transcranial Direct Current Stimulation and Rehabilitation to Ameliorate Impairments in Neurocognition After Stroke

for Ischemic Stroke

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 90

Code: NCT04897334·Recruiting·Listed May 2021

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Sildenafil for Microvasculopathy in Chronic TBI

for Traumatic Brain Injury

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 70

Code: NCT05782244·Phase 2·Recruiting·Listed Mar 2023

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Surviving Daily Life

for Stress

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: Female·Age: 40+

Code: NCT07054723·Recruiting·Listed Jul 2025

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Parkinson's Disease and Movement Disorders Clinical Database

for Parkinson Disease

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT04997642·Recruiting·Listed Aug 2021

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Timing Impact of Early vs. Late Cranioplasty on Hemicraniectomy Outcomes

for Craniocerebral Trauma

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06632587·Recruiting·Listed Oct 2024

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Epilepsy Learning Healthcare System (ELHS)

for Epilepsy

Sites in Philadelphia, Hershey +11 more locations

Sponsor: Epilepsy Foundation of America

Sex: All·Age: All ages

Code: NCT06265103·Recruiting·Listed Feb 2024

Apply to this trial

Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia

for Aphasia

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 40 - 85

Code: NCT06842745·Phase 2·Recruiting·Listed Feb 2025

Apply to this trial

The ME&MG Digital Solution for Autonomous Assessment of Myasthenia Gravis

for Myasthenia Gravis

Sites in Philadelphia +9 more locations

Sponsor: Ad scientiam

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05564936·Recruiting·Listed Oct 2022

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Adaptive Neurostimulation to Restore Sleep in Parkinson's Disease (Aim 2)

for Parkinson's Disease

Sites in Philadelphia +1 more location

Sponsor: University of Nebraska

Sex: All·Age: 18 - 80

Code: NCT05070013·Recruiting·Listed Oct 2021

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Environmental and Sensory Intervention for Nursing Home Residents With Dementia Who Exhibit Persistent Vocalizations

for Dementia

1 location in Philadelphia

Sponsor: Drexel University

Sex: All·Age: 50+

Code: NCT06568107·Recruiting·Listed Aug 2024

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A Study to Investigate the Safety and Pharmacodynamics of a Single Intrathecal Injection (IT) of INS1202 in Participants With Amyotrophic Lateral Sclerosis (ALS)

for Amyotrophic Lateral Sclerosis

Sites in Philadelphia +6 more locations

Sponsor: Insmed Gene Therapy LLC

Sex: All·Age: 18 - 79

Code: NCT07290062·Phase 1·Recruiting·Listed Dec 2025

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Conditions in Brain disorders (Philadelphia, PA)

Stroke· 22 Parkinson's disease· 12 Traumatic brain injury (TBI)· 9 Epilepsy· 8 Alzheimer's disease· 7 ALS (amyotrophic lateral sclerosis)· 7 Myasthenia gravis· 6 Mild cognitive impairment (MCI)· 5 Dementia· 5 Multiple sclerosis· 4 Cognitive impairment / decline· 3 Aphasia· 3 Huntington disease· 2 Essential tremor· 1