Clinical Trials at University of Pennsylvania

As of July 2026, 317 paid clinical trials are recruiting at University of Pennsylvania, located at Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Blvd, Philadelphia, PA 19104, phone (215) 898-8001 in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 1, 2026.

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317 clinical trials at University of Pennsylvania

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Prophylactic Reinforcement of Ventral Abdominal Incisions Trial

for Open Midline Laparotomy

31 locations incl. Phoenix

Sponsor: C. R. Bard

Sex: All·Age: 18+

Code: NCT03911700·Recruiting

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A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)

for Graft-versus-host Disease (GVHD)

Drug: Ruxolitinib

30 locations incl. Palo Alto

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT06615050·Phase 3·Recruiting

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Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML

for Leukemia

53 locations incl. Goodyear

Sponsor: Daiichi Sankyo

Sex: All·Age: 18 - 70

Code: NCT06578247·Phase 3·Recruiting

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The GORE VBX FORWARD Clinical Study: A Comparison of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis to Bare Metal Stenting for Patients With Complex Iliac Occlusive Disease

for Aortoiliac Occlusive Disease

26 locations incl. Little Rock

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT05811364·Recruiting

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CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.

for Epithelial Ovarian Cancer

26 locations incl. Phoenix

Sponsor: TORL Biotherapeutics, LLC

Sex: Female·Age: 18+

Code: NCT06690775·Phase 2·Recruiting

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CAR-T Long Term Follow Up (LTFU) Study

for Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program

44 locations incl. Phoenix

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 0 - 100

Code: NCT02445222·Phase 3·Recruiting

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Long-term Characterization of GORE® TAG® Conformable Thoracic Stent Graft With ACTIVE CONTROL System Performance

for Vascular Disease

24 locations incl. Tucson

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT06658730·Recruiting

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A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

for Ovarian Neoplasms

20 locations incl. Newport Beach

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07213791·Phase 1·Recruiting

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A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT1988 in Participants at Clinical High Risk for Psychosis

for Clinical High Risk for Psychosis (CHR)

15 locations incl. Irvine

Sponsor: Monument Therapeutics Limited

Sex: All·Age: 17 - 30

Code: NCT07226895·Phase 1, Phase 2·Recruiting

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Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

for Solid Tumor Malignancies

13 locations incl. Denver

Sponsor: Tasca Therapeutics

Sex: All·Age: 18+

Code: NCT07030257·Phase 1, Phase 2·Recruiting

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A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

for Advanced Solid Tumors With KRAS G12C Mutations

Drug: FMC-376

15 locations incl. La Jolla

Sponsor: Frontier Medicines Corporation

Sex: All·Age: 18+

Code: NCT06244771·Phase 1, Phase 2·Recruiting

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A Study to Evaluate Del-brax (Also Referred to as AOC 1020) in Participants With FSHD

for Facioscapulohumeral Muscular Dystrophy

14 locations incl. Orange

Sponsor: Avidity Biosciences, Inc.

Sex: All·Age: 16 - 70

Code: NCT07038200·Phase 3·Recruiting

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Diagnosing Epilepsy To EffeCT Change

for Epilepsy

18 locations incl. Phoenix

Sponsor: Epiminder America, Inc.

Sex: All·Age: 18 - 75

Code: NCT07110337·Recruiting

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A Study of JZP815 Oral Capsules in Adult Participants With Advanced or Metastatic Solid Tumors Harboring Mitogen Activated Protein Kinase (MAPK) Pathway Alterations to Investigate the Safety, Dosing, and Antitumor Activity of JZP815

for Advanced Cancer

15 locations incl. Los Angeles

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT05557045·Phase 1·Recruiting

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The MIRROR Registry: Minimally Invasive IntRaceRebral HemORrhage Evacuation

for Supratentorial Hemorrhage

20 locations incl. Burbank

Sponsor: Integra LifeSciences Corporation

Sex: All·Age: 18+

Code: NCT04494295·Recruiting

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A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

for Acute Myeloid Leukemia

Drug: Revumenib

22 locations incl. Duarte

Sponsor: Syndax Pharmaceuticals

Sex: All·Age: 30 Days+

Code: NCT04065399·Phase 1, Phase 2·Recruiting

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Tissue Reinforcement for Breast Reconstruction (TRBR) Pivotal Clinical Study (REDEFINE)

for Breast Reconstruction Surgery

20 locations incl. Scottsdale

Sponsor: W.L.Gore & Associates

Sex: Female·Age: 22+

Code: NCT06556654·Recruiting

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A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)

for Carcinoma, Non-Small-Cell Lung

16 locations incl. Farmington

Sponsor: Johnson & Johnson Enterprise Innovation Inc.

Sex: All·Age: 18+

Code: NCT06667908·Phase 2·Recruiting

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A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms

for Neoplasms

11 locations incl. Duarte

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06150157·Phase 1·Recruiting

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A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy

for Symptomatic Genetic Dilated Cardiomyopathy

18 locations incl. Birmingham

Sponsor: Kardigan, Inc.

Sex: All·Age: 18+

Code: NCT07210723·Phase 2, Phase 3·Recruiting

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TVMR With the INNOVALVE System Trial - Early Feasibility Study

for Mitral Valve Regurgitation (Degenerative or Functional)

20 locations incl. Los Angeles

Sponsor: Edwards Lifesciences

Sex: All·Age: 18+

Code: NCT04919980·Recruiting

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Phase 1/2 Study of PYX-201 in Combination With Pembrolizumab in Advanced Solid Tumors

for Advanced Solid Tumors

11 locations incl. San Diego

Sponsor: Pyxis Oncology, Inc

Sex: All·Age: 18+

Code: NCT06795412·Phase 1, Phase 2·Recruiting

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A Study to Test Whether Spesolimab Helps People With a Skin Condition Called Pyoderma Gangrenosum

for Pyoderma Gangrenosum

20 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06624670·Phase 3·Recruiting

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Acellular Dermal Matrix Investigation in Breast Reconstruction

for Breast Reconstruction

13 locations incl. Little Rock

Sponsor: RTI Surgical

Sex: Female·Age: 22+·Accepts healthy volunteers

Code: NCT06456554·Recruiting

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RevCore for In Stent Thrombosis

for In-stent Thrombosis

16 locations incl. New Haven

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT06394739·Recruiting

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A Study to Evaluate the Safety of INCA33890 in Participants With Advanced or Metastatic Solid Tumors

for Solid Tumors

11 locations incl. Los Angeles

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT05836324·Phase 1·Recruiting

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Evaluate REC-4881 in Participants With Familial Adenomatous Polyposis (FAP)

for Familial Adenomatous Polyposis

17 locations incl. Scottsdale

Sponsor: Recursion Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT05552755·Phase 1, Phase 2·Recruiting

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A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma

for Multiple Myeloma

13 locations incl. San Francisco

Sponsor: K36 Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05651932·Phase 1·Recruiting

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PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches

for Aneurysm

10 locations incl. Aurora

Sponsor: Vascutek Ltd.

Sex: All·Age: 18+

Code: NCT04545502·Recruiting

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A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmoglein 3 Chimeric Autoantibody Receptor T Cells [DSG3-CAART] or CD19-specific Chimeric Antigen Receptor T Cells [CABA-201]) in Subjects With Active, Pemphigus Vulgaris (RESET-PV)

for Pemphigus Vulgaris

13 locations incl. Redwood City

Sponsor: Cabaletta Bio

Sex: All·Age: 18+

Code: NCT04422912·Phase 1, Phase 2·Recruiting

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Terumo Aortic Global Endovascular Registry

for Abdominal Aortic Aneurysm

17 locations incl. Long Beach

Sponsor: Vascutek Ltd.

Sex: All·Age: 18+

Code: NCT04246463·Recruiting

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Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up

for Epilepsy

12 locations incl. Phoenix

Sponsor: Epiminder America, Inc.

Sex: All·Age: 18 - 75

Code: NCT07110454·Recruiting

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The Use of p48/64 MW HPC Flow Modulation Device in the Treatment of Wide-necked Intracranial Aneurysms

for Hemorrhagic Stroke

21 locations incl. Phoenix

Sponsor: phenox Inc.

Sex: All·Age: 18+

Code: NCT07143019·Recruiting

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A Study of the Efficacy and Safety of Lisocabtagene Maraleucel (Liso-cel) as First-Line Therapy in Adults With Transplant-Ineligible Primary Central Nervous System Lymphoma

for Lymphoma

14 locations incl. Aurora

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT07015242·Phase 2·Recruiting

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Real-World Data Collection of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis When Used in Covered Endovascular Reconstruction of the Aortic Bifurcation (CERAB) to Treat Aortoiliac Occlusive Disease

for Aortoiliac Occlusive Disease

19 locations incl. Fresno

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18 - 100

Code: NCT06872905·Recruiting

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Cardiac RADIoablation Versus Repeat Catheter Ablation: a Pivotal Randomized Clinical Trial Evaluating Safety and Efficacy for Patients With High-risk Refractory Ventricular Tachycardia (RADIATE-VT)

for Tachycardia, Ventricular

11 locations incl. Los Angeles

Sponsor: Varian, a Siemens Healthineers Company

Sex: All·Age: 18+

Code: NCT05765175·Recruiting

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Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration

for Solid Tumors

17 locations incl. Duarte

Sponsor: ORIC Pharmaceuticals

Sex: All·Age: 18+

Code: NCT05315700·Phase 1, Phase 2·Recruiting

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Collection of Samples USOPTIVAL Study

for Colorectal Cancer (CRC)

16 locations incl. Chula Vista

Sponsor: Universal Diagnostics

Sex: All·Age: 45 - 84·Accepts healthy volunteers

Code: NCT04792684·Recruiting

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An Early Feasibility Study of the HighLife 28mm Trans-Septal Transcatheter Mitral Valve Replacement System

for Mitral Regurgitation

10 locations incl. Tucson

Sponsor: HighLife SAS

Sex: All·Age: 18+

Code: NCT04029337·Recruiting

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Study Assessing MTD, Safety, Tolerability, PK and Anti-tumor Effects of LNS8801alone and With Pembrolizumab

for Solid Tumor, Adult

10 locations incl. Los Angeles

Sponsor: Linnaeus Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT04130516·Phase 1, Phase 2·Recruiting

Apply to this trial